Retraction: Epithelial Membrane Protein-2 Promotes Endometrial Tumor Formation through Activation of FAK and Src (PLoS ONE (2011) 6:5 (e19945) DOI: 10.1371/journal.pone.0019945);Epithelial membrane protein-2 promotes endometrial tumor formation through activation of FAK and SRC

PLoS ONE

Volumn 6, Issue 5, 2011, Pages

  Fu, Maoyong ^a   Rao, Rajiv ^a   Sudhakar, Deepthi ^a   Hogue, Claire P ^a   Rutta, Zach ^a   Morales, Shawn ^b   Gordon, Lynn K ^b   Braun, Jonathan ^a   Goodglick, Lee ^a   Wadehra, Madhuri ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b JULES STEIN EYE INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EPITHELIAL MEMBRANE PROTEIN 2; FOCAL ADHESION KINASE; INTEGRIN; MEMBRANE PROTEIN; PROTEIN TYROSINE KINASE; UNCLASSIFIED DRUG; EMP2 PROTEIN, HUMAN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER CELL CULTURE; CARCINOGENESIS; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; DISEASE ASSOCIATION; ENDOMETRIUM CANCER; ENZYME ACTIVATION; ENZYME LOCALIZATION; ENZYME PHOSPHORYLATION; FEMALE; HUMAN; HUMAN CELL; LIPID RAFT; MOUSE; NONHUMAN; PHENOTYPE; PROGNOSIS; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TUMOR XENOGRAFT; WOUND HEALING; ANIMAL; BAGG ALBINO MOUSE; CELL MEMBRANE; CELL MOTION; ENDOMETRIUM TUMOR; ENZYMOLOGY; METABOLISM; PATHOLOGY; PHOSPHORYLATION; PRECANCER; PROTEIN BINDING; PROTEIN TRANSPORT; TUMOR CELL LINE; TUMOR VOLUME;

ANIMALS; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; ENDOMETRIAL NEOPLASMS; ENZYME ACTIVATION; FEMALE; FOCAL ADHESION PROTEIN-TYROSINE KINASES; HUMANS; MEMBRANE GLYCOPROTEINS; MEMBRANE MICRODOMAINS; MICE; MICE, INBRED BALB C; PHOSPHORYLATION; PRECANCEROUS CONDITIONS; PROTEIN BINDING; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES; TUMOR BURDEN; WOUND HEALING;

EID: 79957625159     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0276151     Document Type: Erratum

References (43)

1. Creasman WT, Odicino F, Maisonneuve P, Beller U, Benedet JL, et al. (2001) Carcinoma of the corpus uteri. J Epidemiol Biostat 6: 47-86.
2. Denschlag D, Tan L, Patel S, Kerim-Dikeni A, Souhami L, et al. (2007) Stage III endometrial cancer: preoperative predictability, prognostic factors, and treatment outcome. Am J Obstet Gynecol 196: 546 e541-547.
3. Gossett DR, Alo P, Bristow RE, Galati M, Kyshtoobayeva A, et al. (2004) Inability of immunohistochemistry to predict clinical outcomes of endometrial cancer patients. IntJ GynecolCancer 14: 145-151.
4. Habeeb O, Goodglick L, Soslow RA, Rao RG, Gordon LK, et al. (2010) Epithelial membrane protein-2 expression is an early predictor of endometrial cancer development. Cancer 116: 4718-4726.
5. Wadehra M, Natarajan S, Seligson DB, Williams CJ, Hummer AJ, et al. (2006) Expression of epithelial membrane protein-2 is associated with endometrial adenocarcinoma of unfavorable outcome. Cancer 107: 90-98.
6. Wadehra M, Forbes A, Pushkarna N, Goodglick L, Gordon LK, et al. (2005) Epithelial membrane protein-2 regulates surface expression of alphavbeta3 integrin in the endometrium. DevBiol 287: 336-345.
7. Wadehra M, Goodglick L, Braun J, (2004) The tetraspan protein EMP2 modulates the surface expression of caveolins and glycosylphosphatidyl inositol-linked proteins. Mol Biol Cell 15: 2073-2083.
8. Wadehra M, Su H, Gordon LK, Goodglick L, Braun J, (2003) The tetraspan protein EMP2 increases surface expression of class I major histocompatibility complex proteins and susceptibility to CTL-mediated cell death Clinical Immunology 107: 129-136.
9. Lajoie P, Goetz JG, Dennis JW, Nabi IR, (2009) Lattices, rafts, and scaffolds: domain regulation of receptor signaling at the plasma membrane. J Cell Biol 185: 381-385.
10. Patra SK, (2008) Dissecting lipid raft facilitated cell signaling pathways in cancer. Biochim Biophys Acta 1785: 182-206.
11. Poveda JA, Fernandez AM, Encinar JA, Gonzalez-Ros JM, (2008) Protein-promoted membrane domains. Biochim Biophys Acta 1778: 1583-1590.
12. Morales SA, Mareninov S, Coulam P, Wadehra M, Goodglick L, et al. (2009) Functional consequences of interactions between FAK and epithelial membrane protein 2 (EMP2). Invest Ophthalmol Vis Sci 50: 4949-4956.
13. Morales SA, Mareninov S, Wadehra M, Zhang L, Goodglick L, et al. (2009) FAK activation and the role of epithelial membrane protein 2 (EMP2) in collagen gel contraction. Invest Ophthalmol Vis Sci 50: 462-469.
14. Shimazaki K, Wadehra M, Forbes A, Chan AM, Goodglick L, et al. (2007) Epithelial membrane protein 2 modulates infectivity of Chlamydia muridarum (MoPn). Microbes Infect 9: 1003-1010.
15. Agus DB, Scher HI, Higgins B, Fox WD, Heller G, et al. (1999) Response of Prostate Cancer to Anti-Her-2/neu Antibody in Androgen-dependent and-independent Human Xenograft Models. Cancer Res 59: 4761-4764.
16. Brey EM, Lalani Z, Johnston C, Wong M, McIntire LV, et al. (2003) Automated selection of DAB-labeled tissue for immunohistochemical quantification. J Histochem Cytochem 51: 575-584.
17. Wadehra M, Iyer R, Goodglick L, Braun J, (2002) The tetraspan protein epithelial membrane protein-2 interacts with beta1 integrins and regulates adhesion. J Biol Chem 277: 41094-41100.
18. Acconcia F, Barnes CJ, Kumar R, (2006) Estrogen and tamoxifen induce cytoskeletal remodeling and migration in endometrial cancer cells. Endocrinology 147: 1203-1212.
19. Morales S, Mareninov S, Prasad P, Wadehra M, Braun J, et al. (2007) Collagen Gel Contraction by ARPE-19 is mediated by a FAK-Src dependent pathway. Experimental Eye Research 85: 790-798.
20. Barnett SF, Defeo-Jones D, Fu S, Hancock PJ, Haskell KM, et al. (2005) Identification and characterization of pleckstrin-homology-domain-dependent and isoenzyme-specific Akt inhibitors. Biochem J 385: 399-408.
21. Wang MY, Lu KV, Zhu S, Dia EQ, Vivanco I, et al. (2006) Mammalian target of rapamycin inhibition promotes response to epidermal growth factor receptor kinase inhibitors in PTEN-deficient and PTEN-intact glioblastoma cells. Cancer Res 66: 7864-7869.
22. Lu KV, Zhu S, Cvrljevic A, Huang TT, Sarkaria S, et al. (2009) Fyn and SRC are effectors of oncogenic epidermal growth factor receptor signaling in glioblastoma patients. Cancer Res 69: 6889-6898.
23. Wadehra M, Mainigi M, Morales SA, Rao RG, Gordon LK, et al. (2008) Steroid hormone regulation of EMP2 expression and localization in the endometrium. Reprod Biol Endocrinol 6: 15.
24. Levy S, Shoham T, (2005) The tetraspanin web modulates immune-signalling complexes. NatRevImmunol 5: 136-148.
25. Maecker HT, Todd SC, Levy S, (1997) The tetraspanin superfamily: molecular facilitators. FASEB J 11: 428-442.
26. Naroeni A, Porte F, (2002) Role of cholesterol and the ganglioside GM(1) in entry and short-term survival of Brucella suis in murine macrophages. Infect Immun 70: 1640-1644.
27. Salzer U, Prohaska R, (2001) Stomatin, flotillin-1, and flotillin-2 are major integral proteins of erythrocyte lipid rafts. Blood 97: 1141-1143.
28. Cortese K, Sahores M, Madsen CD, Tacchetti C, Blasi F, (2008) Clathrin and LRP-1-independent constitutive endocytosis and recycling of uPAR. PLoS One 3: e3730.
29. Wang C, Yoo Y, Fan H, Kim E, Guan KL, et al. (2010) Regulation of Integrin beta 1 recycling to lipid rafts by Rab1a to promote cell migration. J Biol Chem 285: 29398-29405.
30. Baillat G, Siret C, Delamarre E, Luis J, (2008) Early adhesion induces interaction of FAK and Fyn in lipid domains and activates raft-dependent Akt signaling in SW480 colon cancer cells. Biochim Biophys Acta 1783: 2323-2331.
31. Hakomori SI, (2010) Glycosynaptic microdomains controlling tumor cell phenotype through alteration of cell growth, adhesion, and motility. FEBS Lett 584: 1901-1906.
32. Park EK, Park MJ, Lee SH, Li YC, Kim J, et al. (2009) Cholesterol depletion induces anoikis-like apoptosis via FAK down-regulation and caveolae internalization. J Pathol 218: 337-349.
33. Sieg DJ, Hauck CR, Ilic D, Klingbeil CK, Schaefer E, et al. (2000) FAK integrates growth-factor and integrin signals to promote cell migration. Nat Cell Biol 2: 249-256.
34. Berditchevski F, Odintsova E, (1999) Characterization of integrin-tetraspanin adhesion complexes: role of tetraspanins in integrin signaling. JCell Biol 146: 477-492.
35. Kawaguchi T, Yamashita Y, Kanamori M, Endersby R, Bankiewicz KS, et al. (2006) The PTEN/Akt pathway dictates the direct alphaVbeta3-dependent growth-inhibitory action of an active fragment of tumstatin in glioma cells in vitro and in vivo. Cancer Res 66: 11331-11340.
36. Yunta M, Lazo PA, (2003) Tetraspanin proteins as organisers of membrane microdomains and signalling complexes. Cell Signal 15: 559-564.
37. Kobayashi T, Vischer UM, Rosnoblet C, Lebrand C, Lindsay M, et al. (2000) The tetraspanin CD63/lamp3 cycles between endocytic and secretory compartments in human endothelial cells. MolBiolCell 11: 1829-1843.
38. Berditchevski F, (2001) Complexes of tetraspanins with integrins: more than meets the eye. J Cell Sci 114: 4143-4151.
39. Stipp CS, (2010) Laminin-binding integrins and their tetraspanin partners as potential antimetastatic targets. Expert Rev Mol Med 12: e3.
40. Zevian S, Winterwood NE, Stipp CS, (2011) Structure-Function Analysis of Tetraspanin CD151 Reveals Distinct Requirements for Tumor Cell Behaviors Mediated by α3{beta}1 versus α6{beta}4 Integrin. J Biol Chem 286: 7496-7506.
41. Hemler ME, (2005) Tetraspanin functions and associated microdomains. Nat Rev Mol Cell Biol 6: 801-811.
42. Park DW, Ryu HS, Choi DS, Park YH, Chang KH, et al. (2001) Localization of matrix metalloproteinases on endometrial cancer cell invasion in vitro. Gynecol Oncol 82: 442-449.
43. Desouki MM, Rowan BG, (2004) SRC kinase and mitogen-activated protein kinases in the progression from normal to malignant endometrium. Clin Cancer Res 10: 546-555.