메뉴 건너뛰기




Volumn 375, Issue 1-2, 2013, Pages 199-206

Contribution of hydrogen sulfide and nitric oxide to exercise-induced attenuation of aortic remodeling and improvement of endothelial function in spontaneously hypertensive rats

Author keywords

Aortic remodeling; Endothelial dysfunction; Exercise training; Hydrogen sulfide; Nitric oxide; Spontaneously hypertensive rats

Indexed keywords

3 MERCAPTOPYRUVATE SULFURTRANSFERASE; 3 MERCAPTOPYRUVIC ACID; ACETYLCHOLINE; CATALASE; CYSTATHIONINE BETA SYNTHASE; CYSTATHIONINE GAMMA LYASE; DIMETHYLARGININASE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; HYDROGEN SULFIDE; MALONALDEHYDE; MESSENGER RNA; N(G),N(G) DIMETHYLARGININE; NITRIC OXIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

EID: 84873059387     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-012-1542-1     Document Type: Article
Times cited : (37)

References (41)
  • 1
    • 0028918698 scopus 로고
    • Impaired endothelium-dependent vasodilation in patients with essential hypertension:evidence that nitric oxide abnormality is not localized to a single signal transduction pathway
    • 7882481 10.1161/01.CIR.91.6.1732 1:STN:280:DyaK2M7ovVehug%3D%3D
    • Panza JA, García CE, Kilcoyne CM, Quyyumi AA, Cannon RO (1995) Impaired endothelium-dependent vasodilation in patients with essential hypertension:evidence that nitric oxide abnormality is not localized to a single signal transduction pathway. Circulation 91:1732-1738
    • (1995) Circulation , vol.91 , pp. 1732-1738
    • Panza, J.A.1    García, C.E.2    Kilcoyne, C.M.3    Quyyumi, A.A.4    Cannon, R.O.5
  • 2
    • 0021048924 scopus 로고
    • Role of endothelium in dilator responses of spontaneously hypertensive rat arteries
    • 6654451 10.1161/01.HYP.5.6.881 1:CAS:528:DyaL2cXksF2itQ%3D%3D
    • Konishi M, Su C (1983) Role of endothelium in dilator responses of spontaneously hypertensive rat arteries. Hypertension 5:881-886
    • (1983) Hypertension , vol.5 , pp. 881-886
    • Konishi, M.1    Su, C.2
  • 3
    • 83455196999 scopus 로고    scopus 로고
    • Defective nitric oxide production impairs angiotensin II-induced Na/K-ATPase regulation in spontaneously hypertensive rats
    • 21900450 10.1152/ajprenal.00270.2011 1:CAS:528:DC%2BC38XitVemt7o%3D
    • Javkhedkar AA, Lokhandwala MF, Banday AA (2012) Defective nitric oxide production impairs angiotensin II-induced Na/K-ATPase regulation in spontaneously hypertensive rats. Am J Physiol Renal Physiol 302:F47-F51
    • (2012) Am J Physiol Renal Physiol , vol.302
    • Javkhedkar, A.A.1    Lokhandwala, M.F.2    Banday, A.A.3
  • 4
    • 79954587083 scopus 로고    scopus 로고
    • Mechanism of vasorelaxation and role of endogenous hydrogen sulfide production in mouse aorta
    • 21336541 10.1007/s00210-011-0608-z 1:CAS:528:DC%2BC3MXis1yjs78%3D
    • Al-Magableh MR, Hart JL (2011) Mechanism of vasorelaxation and role of endogenous hydrogen sulfide production in mouse aorta. Naunyn Schmiedebergs Arch Pharmacol 383:403-413
    • (2011) Naunyn Schmiedebergs Arch Pharmacol , vol.383 , pp. 403-413
    • Al-Magableh, M.R.1    Hart, J.L.2
  • 5
    • 0037337890 scopus 로고    scopus 로고
    • Vitamins reverse endothelial dysfunction through regulation of eNOS and NAD(P)H oxidase activities
    • 12623955 10.1161/01.HYP.0000057421.28533.37
    • Ulker S, McKeown PP, Bayraktutan U (2003) Vitamins reverse endothelial dysfunction through regulation of eNOS and NAD(P)H oxidase activities. Hypertension 41:534-539
    • (2003) Hypertension , vol.41 , pp. 534-539
    • Ulker, S.1    McKeown, P.P.2    Bayraktutan, U.3
  • 6
    • 0031840214 scopus 로고    scopus 로고
    • Upregulation of renal and vascular nitric oxide synthase in young spontaneously hypertensive rats
    • 9622137 10.1161/01.HYP.31.6.1248 1:CAS:528:DyaK1cXjvVaqsLw%3D
    • Vaziri ND, Ni Z, Oveisi F (1998) Upregulation of renal and vascular nitric oxide synthase in young spontaneously hypertensive rats. Hypertension 31:1248-1254
    • (1998) Hypertension , vol.31 , pp. 1248-1254
    • Vaziri, N.D.1    Ni, Z.2    Oveisi, F.3
  • 7
    • 0029021148 scopus 로고
    • Hypertension in mice lacking the gene for endothelial nitric oxide synthase
    • 7545787 10.1038/377239a0 1:CAS:528:DyaK2MXot1Gltbk%3D
    • Huang PL, Huang Z, Mashimo H, Bloch KD, Moskowitz MA, Bevan JA, Fishman MC (1995) Hypertension in mice lacking the gene for endothelial nitric oxide synthase. Nature 377:239-242
    • (1995) Nature , vol.377 , pp. 239-242
    • Huang, P.L.1    Huang, Z.2    Mashimo, H.3    Bloch, K.D.4    Moskowitz, M.A.5    Bevan, J.A.6    Fishman, M.C.7
  • 8
    • 84869500110 scopus 로고    scopus 로고
    • The new nitric oxide donor 2-nitrate-1,3-dibuthoxypropan alters autonomic function in spontaneously hypertensive rats
    • 23141524 10.1016/j.autneu.2012.10.002
    • França-Silva MS, Monteiro MM, Queiroz TM, Santos AF, Athayde-Filho PF, Braga VA (2012) The new nitric oxide donor 2-nitrate-1,3-dibuthoxypropan alters autonomic function in spontaneously hypertensive rats. Auton Neurosci 171:28-35
    • (2012) Auton Neurosci , vol.171 , pp. 28-35
    • França-Silva, M.S.1    Monteiro, M.M.2    Queiroz, T.M.3    Santos, A.F.4    Athayde-Filho, P.F.5    Braga, V.A.6
  • 9
    • 35348993710 scopus 로고    scopus 로고
    • Chronic sodium hydrosulfide treatment decreases medial thickening of intramyocardial coronary arterioles, interstitial fibrosis, and ROS production in spontaneously hypertensive rats
    • 17630351 10.1152/ajpheart.00088.2007 1:CAS:528:DC%2BD2sXht1WlurvE
    • Shi YX, Chen Y, Zhu YZ, Huang GY, Moore PK, Huang SH, Yao T, Zhu YC (2007) Chronic sodium hydrosulfide treatment decreases medial thickening of intramyocardial coronary arterioles, interstitial fibrosis, and ROS production in spontaneously hypertensive rats. Am J Physiol Heart Circ Physiol 293:H2093-H2100
    • (2007) Am J Physiol Heart Circ Physiol , vol.293
    • Shi, Y.X.1    Chen, Y.2    Zhu, Y.Z.3    Huang, G.Y.4    Moore, P.K.5    Huang, S.H.6    Yao, T.7    Zhu, Y.C.8
  • 11
    • 0030817364 scopus 로고    scopus 로고
    • Time course of enhanced endothelium mediated dilation in aorta of trained rats
    • 9372482 10.1097/00005768-199711000-00011 1:CAS:528:DyaK2sXns1OqtL0%3D
    • Delp MD, Laughlin MH (1997) Time course of enhanced endothelium mediated dilation in aorta of trained rats. Med Sci Sports Exerc 29:1454-1461
    • (1997) Med Sci Sports Exerc , vol.29 , pp. 1454-1461
    • Delp, M.D.1    Laughlin, M.H.2
  • 12
    • 0028790485 scopus 로고
    • Chronic exercise enhances endothelium-mediated dilation in spontaneously hypertensive rats
    • 7475973 10.1016/0024-3205(95)02127-5 1:STN:280:DyaK28%2FotV2ktw%3D%3D
    • Yen MH, Yang JH, Sheu JR, Lee YM, Ding YA (1995) Chronic exercise enhances endothelium-mediated dilation in spontaneously hypertensive rats. Life Sci 57:2205-2213
    • (1995) Life Sci , vol.57 , pp. 2205-2213
    • Yen, M.H.1    Yang, J.H.2    Sheu, J.R.3    Lee, Y.M.4    Ding, Y.A.5
  • 13
    • 78249263518 scopus 로고    scopus 로고
    • Exercise training enhances elastin, fibrillin and nitric oxide in the aorta wall of spontaneously hypertensive rats
    • 10.1016/j.yexmp.2010.08.004 1:CAS:528:DC%2BC3cXhsVans7vI
    • Moraes-Teixeira JA, Felix A, Fernandes-Santos C, Moura AS, Mandarim-de-Lacerda CA, Carvalho JJ (2010) Exercise training enhances elastin, fibrillin and nitric oxide in the aorta wall of spontaneously hypertensive rats. Exp Mol Pathol 89:351-357
    • (2010) Exp Mol Pathol , vol.89 , pp. 351-357
    • Moraes-Teixeira, J.A.1    Felix, A.2    Fernandes-Santos, C.3    Moura, A.S.4    Mandarim-De-Lacerda, C.A.5    Carvalho, J.J.6
  • 14
    • 3142725555 scopus 로고    scopus 로고
    • Physical conditioning modulates rat cardiac VEGF gene expression in nitric oxide-deficient hypertension
    • 15249212 10.1016/j.bbrc.2004.06.058 1:CAS:528:DC%2BD2cXls1eis70%3D
    • Husain K (2004) Physical conditioning modulates rat cardiac VEGF gene expression in nitric oxide-deficient hypertension. Biochem Biophys Res Commun 320:1169-1174
    • (2004) Biochem Biophys Res Commun , vol.320 , pp. 1169-1174
    • Husain, K.1
  • 15
    • 84858075670 scopus 로고    scopus 로고
    • Chronic hydrogen-rich saline treatment attenuates vascular dysfunction in spontaneous hypertensive rats
    • 22342731 10.1016/j.bcp.2012.01.031 1:CAS:528:DC%2BC38XjtF2js74%3D
    • Zheng H, Yu YS (2012) Chronic hydrogen-rich saline treatment attenuates vascular dysfunction in spontaneous hypertensive rats. Biochem Pharmacol 83:1269-1277
    • (2012) Biochem Pharmacol , vol.83 , pp. 1269-1277
    • Zheng, H.1    Yu, Y.S.2
  • 16
    • 27144471111 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme inhibitors. A new mechanism of action
    • 16216963 10.1161/CIRCULATIONAHA.104.528695 1:CAS:528:DC%2BD2MXhtV2rt7vO
    • Peng H, Carretero OA, Vuljaj N, Liao TD, Motivala A, Peterson EL, Rhaleb NE (2005) Angiotensin-converting enzyme inhibitors. A new mechanism of action. Circulation 112:2436-2445
    • (2005) Circulation , vol.112 , pp. 2436-2445
    • Peng, H.1    Carretero, O.A.2    Vuljaj, N.3    Liao, T.D.4    Motivala, A.5    Peterson, E.L.6    Rhaleb, N.E.7
  • 17
    • 84943124687 scopus 로고
    • Some new staining methods of wide applicability including a rapid differential stain for elastic tissue
    • 10.1001/jama.1908.25310370042004a
    • Verhoeff FH (1908) Some new staining methods of wide applicability including a rapid differential stain for elastic tissue. JAMA 50:876-877
    • (1908) JAMA , vol.50 , pp. 876-877
    • Verhoeff, F.H.1
  • 18
    • 5344246626 scopus 로고    scopus 로고
    • Endogenous nitric oxide synthesis inhibitor asymmetric dimethyl l-arginine accelerates endothelial cell senescence
    • 15308550 10.1161/01.ATV.0000141843.77133.fc 1:CAS:528: DC%2BD2cXotVOnsLc%3D
    • Scalera F, Borlak J, Beckmann B, Martens-Lobenhoffer J, Thum T, Tager M, Bode-Boger SM (2004) Endogenous nitric oxide synthesis inhibitor asymmetric dimethyl l-arginine accelerates endothelial cell senescence. Arterioscler Thromb Vasc Biol 24:1816-1822
    • (2004) Arterioscler Thromb Vasc Biol , vol.24 , pp. 1816-1822
    • Scalera, F.1    Borlak, J.2    Beckmann, B.3    Martens-Lobenhoffer, J.4    Thum, T.5    Tager, M.6    Bode-Boger, S.M.7
  • 19
    • 60549116172 scopus 로고    scopus 로고
    • Chronic NF-kB blockade reduces cytosolic and mitochondrial oxidative stress and attenuates renal injury and hypertension in SHR
    • 19073636 10.1152/ajprenal.90628.2008 1:CAS:528:DC%2BD1MXitVejtbc%3D
    • Elks CM, Mariappan N, Haque M, Guggilam A, Majid DS, Francis J (2009) Chronic NF-kB blockade reduces cytosolic and mitochondrial oxidative stress and attenuates renal injury and hypertension in SHR. Am J Physiol Renal Physiol 296:F298-F305
    • (2009) Am J Physiol Renal Physiol , vol.296
    • Elks, C.M.1    Mariappan, N.2    Haque, M.3    Guggilam, A.4    Majid, D.S.5    Francis, J.6
  • 20
    • 34447523496 scopus 로고    scopus 로고
    • NADPH oxidase-derived superoxide anion mediates angiotensin II-enhanced carotid body chemoreceptor sensitivity in heart failure rabbits
    • 17499230 10.1016/j.cardiores.2007.04.006 1:CAS:528:DC%2BD2sXot1ykt7k%3D
    • Li YL, Gao L, Zucker IH, Schultz HD (2007) NADPH oxidase-derived superoxide anion mediates angiotensin II-enhanced carotid body chemoreceptor sensitivity in heart failure rabbits. Cardiovasc Res 75:546-554
    • (2007) Cardiovasc Res , vol.75 , pp. 546-554
    • Li, Y.L.1    Gao, L.2    Zucker, I.H.3    Schultz, H.D.4
  • 21
    • 36148948616 scopus 로고    scopus 로고
    • TNF-α-induced mitochondrial oxidative stress and cardiac dysfunction, restoration by superoxide dismutase mimetic Tempol
    • 17675574 10.1152/ajpheart.00376.2007 1:CAS:528:DC%2BD2sXhtlGhsL7E
    • Mariappan N, Soorappan RN, Haque M, Sriramula S, Francis J (2007) TNF-α-induced mitochondrial oxidative stress and cardiac dysfunction, restoration by superoxide dismutase mimetic Tempol. Am J Physiol Heart Circ Physiol 293:H2726-H2737
    • (2007) Am J Physiol Heart Circ Physiol , vol.293
    • Mariappan, N.1    Soorappan, R.N.2    Haque, M.3    Sriramula, S.4    Francis, J.5
  • 22
    • 22844434356 scopus 로고    scopus 로고
    • Reduction of blood pressure variability: A new strategy for the treatment of hypertension
    • 15990175 10.1016/j.tips.2005.06.003 1:CAS:528:DC%2BD2MXmvVCqt7c%3D
    • Su DF, Miao CY (2005) Reduction of blood pressure variability: a new strategy for the treatment of hypertension. Trends Pharmacol Sci 26:388-390
    • (2005) Trends Pharmacol Sci , vol.26 , pp. 388-390
    • Su, D.F.1    Miao, C.Y.2
  • 23
    • 0023794431 scopus 로고
    • Baroreflex sensitivity, clinical correlates and cardiovascular morality among patients with a first myocardial infarction: A prospective study
    • 3168190 10.1161/01.CIR.78.4.816 1:STN:280:DyaL1M%2FgtlCqtg%3D%3D
    • La Rovere MT, Specchia G, Mortara A, Specchia G (1988) Baroreflex sensitivity, clinical correlates and cardiovascular morality among patients with a first myocardial infarction: a prospective study. Circulation 78:816-824
    • (1988) Circulation , vol.78 , pp. 816-824
    • La Rovere, M.T.1    Specchia, G.2    Mortara, A.3    Specchia, G.4
  • 24
    • 0030778801 scopus 로고    scopus 로고
    • Arterial baroreflex modulation of heart rate in chronic heart failure: Clinical and hemodynamic correlates and prognostic implications
    • 9396441 10.1161/01.CIR.96.10.3450 1:STN:280:DyaK1c%2FlslWhtQ%3D%3D
    • Mortara A, La Rovere MT, Pinna GD, Prpa A, Maestri R, Febo O, Pozzoli M, Opasich C, Tavazzi L (1997) Arterial baroreflex modulation of heart rate in chronic heart failure: clinical and hemodynamic correlates and prognostic implications. Circulation 96:3450-3458
    • (1997) Circulation , vol.96 , pp. 3450-3458
    • Mortara, A.1    La Rovere, M.T.2    Pinna, G.D.3    Prpa, A.4    Maestri, R.5    Febo, O.6    Pozzoli, M.7    Opasich, C.8    Tavazzi, L.9
  • 25
    • 78549286390 scopus 로고    scopus 로고
    • Effects of low-dose ketanserin on atherosclerosis in rats and rabbits
    • 21076493 10.1139/Y10-079 1:CAS:528:DC%2BC3cXhtlahu7bP
    • Yu YS, Xie HH, Li L, Song SW, Han P, Cai GJ, Su DF (2010) Effects of low-dose ketanserin on atherosclerosis in rats and rabbits. Can J Physiol Pharmacol 88:1054-1060
    • (2010) Can J Physiol Pharmacol , vol.88 , pp. 1054-1060
    • Yu, Y.S.1    Xie, H.H.2    Li, L.3    Song, S.W.4    Han, P.5    Cai, G.J.6    Su, D.F.7
  • 26
    • 33645028643 scopus 로고    scopus 로고
    • Early structural changes of aortic wall in sinoaortic-denervated rats
    • 16620301 10.1111/j.1440-1681.2006.04375.x 1:CAS:528:DC%2BD28Xjslartbo%3D
    • Shen FM, Zhang SH, Xie HH, Jing Q, Wang DS, Su DF (2006) Early structural changes of aortic wall in sinoaortic-denervated rats. Clin Exp Pharmacol Physiol 33:358-363
    • (2006) Clin Exp Pharmacol Physiol , vol.33 , pp. 358-363
    • Shen, F.M.1    Zhang, S.H.2    Xie, H.H.3    Jing, Q.4    Wang, D.S.5    Su, D.F.6
  • 27
    • 70449686289 scopus 로고    scopus 로고
    • Vascular endothelium expresses 3-mercaptopyruvate sulfurtransferase and produces hydrogen sulfide
    • 19605461 10.1093/jb/mvp111 1:CAS:528:DC%2BD1MXhtlyrtrfK
    • Shibuya N, Mikami Y, Kimura Y, Nagahara N, Kimura H (2009) Vascular endothelium expresses 3-mercaptopyruvate sulfurtransferase and produces hydrogen sulfide. J Biochem 146:623-626
    • (2009) J Biochem , vol.146 , pp. 623-626
    • Shibuya, N.1    Mikami, Y.2    Kimura, Y.3    Nagahara, N.4    Kimura, H.5
  • 28
    • 84864568471 scopus 로고    scopus 로고
    • Differential effects of cystathionine-γ-lyase-dependent vasodilatory H(2)S in periadventitial vasoregulation of rat and mouse aortas
    • 22870268 10.1371/journal.pone.0041951
    • Köhn C, Schleifenbaum J, Szijártó IA, Markó L, Dubrovska G, Huang Y, Gollasch M (2012) Differential effects of cystathionine-γ-lyase-dependent vasodilatory H(2)S in periadventitial vasoregulation of rat and mouse aortas. PLoS ONE 7:e41951
    • (2012) PLoS ONE , vol.7 , pp. 41951
    • Köhn, C.1    Schleifenbaum, J.2    Szijártó, I.A.3    Markó, L.4    Dubrovska, G.5    Huang, Y.6    Gollasch, M.7
  • 29
    • 78449276447 scopus 로고    scopus 로고
    • Hydrogen sulfide protects against vascular remodeling from endothelial damage
    • 20352463 10.1007/s00726-010-0550-2 1:CAS:528:DC%2BC3cXhtlaqtLbM
    • Vacek TP, Gillespie W, Tyagi N, Vacek JC, Tyagi SC (2010) Hydrogen sulfide protects against vascular remodeling from endothelial damage. Amino Acids 39:1161-1169
    • (2010) Amino Acids , vol.39 , pp. 1161-1169
    • Vacek, T.P.1    Gillespie, W.2    Tyagi, N.3    Vacek, J.C.4    Tyagi, S.C.5
  • 30
    • 77952390040 scopus 로고    scopus 로고
    • Cystathionine gamma-lyase deficiency and overproliferation of smooth muscle cells
    • 20051385 10.1093/cvr/cvp420 1:CAS:528:DC%2BC3cXmtFKqt70%3D
    • Yang G, Wu L, Bryan S, Khaper N, Mani S, Wang R (2010) Cystathionine gamma-lyase deficiency and overproliferation of smooth muscle cells. Cardiovasc Res 86:487-495
    • (2010) Cardiovasc Res , vol.86 , pp. 487-495
    • Yang, G.1    Wu, L.2    Bryan, S.3    Khaper, N.4    Mani, S.5    Wang, R.6
  • 31
    • 55449104752 scopus 로고    scopus 로고
    • Regulatory effect of hydrogen sulfide on vascular collagen content in spontaneously hypertensive rats
    • 18971538 10.1291/hypres.31.1619 1:CAS:528:DC%2BD1cXhsVOgu7%2FF
    • Zhao X, Zhang LK, Zhang CY, Zeng XJ, Yan H, Jin HF, Tang CS, Du JB (2008) Regulatory effect of hydrogen sulfide on vascular collagen content in spontaneously hypertensive rats. Hypertens Res 31:1619-1630
    • (2008) Hypertens Res , vol.31 , pp. 1619-1630
    • Zhao, X.1    Zhang, L.K.2    Zhang, C.Y.3    Zeng, X.J.4    Yan, H.5    Jin, H.F.6    Tang, C.S.7    Du, J.B.8
  • 32
    • 54949084607 scopus 로고    scopus 로고
    • H2S as a physiologic vasorelaxant: Hypertension in mice with deletion of cystathionine gamma-lyase
    • 18948540 10.1126/science.1162667 1:CAS:528:DC%2BD1cXht1Krt7vM
    • Yang G, Wu L, Jiang B, Yang W, Qi J, Cao K, Meng Q, Mustafa AK, Mu W, Zhang S, Snyder SH, Wang R (2008) H2S as a physiologic vasorelaxant: hypertension in mice with deletion of cystathionine gamma-lyase. Science 322:587-590
    • (2008) Science , vol.322 , pp. 587-590
    • Yang, G.1    Wu, L.2    Jiang, B.3    Yang, W.4    Qi, J.5    Cao, K.6    Meng, Q.7    Mustafa, A.K.8    Mu, W.9    Zhang, S.10    Snyder, S.H.11    Wang, R.12
  • 33
    • 0035016024 scopus 로고    scopus 로고
    • Efficiency of NO donors in substituting the impaired endogenous NO production: Functional and morphological study
    • 11522044
    • Gerová M, Kristek F (2001) Efficiency of NO donors in substituting the impaired endogenous NO production: functional and morphological study. Physiol Res 50:165-173
    • (2001) Physiol Res , vol.50 , pp. 165-173
    • Gerová, M.1    Kristek, F.2
  • 34
    • 0030033842 scopus 로고    scopus 로고
    • Nitric oxide reversibly inhibits the migration of cultured vascular smooth muscle cells
    • 8575065 10.1161/01.RES.78.2.225 1:CAS:528:DyaK28XnsFyhsQ%3D%3D
    • Sarkar R, Meinberg EG, Stanley JC, Gordon D, Webb RC (1996) Nitric oxide reversibly inhibits the migration of cultured vascular smooth muscle cells. Circ Res 78:225-230
    • (1996) Circ Res , vol.78 , pp. 225-230
    • Sarkar, R.1    Meinberg, E.G.2    Stanley, J.C.3    Gordon, D.4    Webb, R.C.5
  • 35
    • 2442689237 scopus 로고    scopus 로고
    • Exercise training improves aortic endothelium-dependent vasorelaxation and determinants of nitric oxide bioavailability in spontaneously hypertensive rats
    • 14752124 10.1152/japplphysiol.01252.2003 1:CAS:528:DC%2BD2cXltV2msLg%3D
    • Graham DA, Rush JW (2004) Exercise training improves aortic endothelium-dependent vasorelaxation and determinants of nitric oxide bioavailability in spontaneously hypertensive rats. J Appl Physiol 96:2088-2096
    • (2004) J Appl Physiol , vol.96 , pp. 2088-2096
    • Graham, D.A.1    Rush, J.W.2
  • 36
    • 78349279285 scopus 로고    scopus 로고
    • Involvement of asymmetric dimethylarginine and Rho kinase in the vascular remodeling in monocrotaline-induced pulmonary hypertension
    • 20840872 10.1016/j.vph.2010.09.002 1:CAS:528:DC%2BC3cXhsValtLvP
    • Li XH, Peng J, Tan N, Wu WH, Li TT, Shi RZ, Li YJ (2010) Involvement of asymmetric dimethylarginine and Rho kinase in the vascular remodeling in monocrotaline-induced pulmonary hypertension. Vascul Pharmacol 53:223-229
    • (2010) Vascul Pharmacol , vol.53 , pp. 223-229
    • Li, X.H.1    Peng, J.2    Tan, N.3    Wu, W.H.4    Li, T.T.5    Shi, R.Z.6    Li, Y.J.7
  • 37
    • 78349275306 scopus 로고    scopus 로고
    • Melatonin prevents hypertension and increased asymmetric dimethylarginine in young spontaneous hypertensive rats
    • 20950359 10.1111/j.1600-079X.2010.00806.x 1:CAS:528:DC%2BC3cXhsVWgurbL
    • Tain YL, Huang LT, Lin IC, Lau YT, Lin CY (2010) Melatonin prevents hypertension and increased asymmetric dimethylarginine in young spontaneous hypertensive rats. J Pineal Res 49:390-398
    • (2010) J Pineal Res , vol.49 , pp. 390-398
    • Tain, Y.L.1    Huang, L.T.2    Lin, I.C.3    Lau, Y.T.4    Lin, C.Y.5
  • 38
    • 0041733065 scopus 로고    scopus 로고
    • Asymmetric dimethylarginine causes hypertension and cardiac dysfunction in humans and is actively metabolized by dimethylarginine dimethylaminohydrolase
    • 12805079 10.1161/01.ATV.0000081742.92006.59 1:CAS:528: DC%2BD3sXlvFaqsL8%3D
    • Achan V, Broadhead M, Malaki M, Whitley G, Leiper J, MacAllister R, Vallance P (2003) Asymmetric dimethylarginine causes hypertension and cardiac dysfunction in humans and is actively metabolized by dimethylarginine dimethylaminohydrolase. Arterioscler Thromb Vasc Biol 23:1455-1459
    • (2003) Arterioscler Thromb Vasc Biol , vol.23 , pp. 1455-1459
    • Achan, V.1    Broadhead, M.2    Malaki, M.3    Whitley, G.4    Leiper, J.5    MacAllister, R.6    Vallance, P.7
  • 39
    • 78049478368 scopus 로고    scopus 로고
    • Effect of endurance exercise training on oxidative stress in spontaneously hypertensive rats (SHR) after emergence of hypertension
    • 20828222 10.3109/10641961003667930 1:CAS:528:DC%2BC3cXhtlGmsL3L
    • Kimura H, Kon N, Furukawa S, Mukaida M, Yamakura F, Matsumoto K, Sone H, Murakami-Murofushi K (2010) Effect of endurance exercise training on oxidative stress in spontaneously hypertensive rats (SHR) after emergence of hypertension. Clin Exp Hypertens 32:407-415
    • (2010) Clin Exp Hypertens , vol.32 , pp. 407-415
    • Kimura, H.1    Kon, N.2    Furukawa, S.3    Mukaida, M.4    Yamakura, F.5    Matsumoto, K.6    Sone, H.7    Murakami-Murofushi, K.8
  • 40
    • 8644277006 scopus 로고    scopus 로고
    • Reactive oxygen species in vascular biology: Implications in hypertension
    • 15338229 10.1007/s00418-004-0696-7 1:CAS:528:DC%2BD2cXoslGitL8%3D
    • Touyz RM, Schiffrin EL (2004) Reactive oxygen species in vascular biology: implications in hypertension. Histochem Cell Biol 122:339-352
    • (2004) Histochem Cell Biol , vol.122 , pp. 339-352
    • Touyz, R.M.1    Schiffrin, E.L.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.