Ceramide PC102 inhibits melanin synthesis via proteasomal degradation of microphthalmia-associated transcription factor and tyrosinase

Molecular and Cellular Biochemistry

Volumn 375, Issue 1-2, 2013, Pages 81-87

  Jeong, Hyo Soon ^a   Choi, Hye Ryung ^b,c   Yun, Hye Young ^a   Baek, Kwang Jin ^a   Kwon, Nyoun Soo ^a   Park, Kyoung Chan ^b,c   Kim, Dong Seok ^a  

^a Chung Ang University College of Medicine   (South Korea)

^b Seoul National University College of Medicine   (South Korea)

^c Seoul National University Bundang Hospital   (South Korea)

Author keywords

Ceramide PC102; Melanin; MITF; Tyrosinase

Indexed keywords

BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; BETA CATENIN; CERAMIDE; GUARANA EXTRACT; MICROPHTHALMIA ASSOCIATED TRANSCRIPTION FACTOR; MONOPHENOL MONOOXYGENASE; PROTEASOME;

ANIMAL CELL; ARTICLE; CELL VIABILITY; DOWN REGULATION; ENZYME ACTIVITY; ENZYME DEGRADATION; MELANOGENESIS; NONHUMAN; PROTEIN SYNTHESIS INHIBITION; SKIN PIGMENTATION; WNT SIGNALING PATHWAY;

AMIDES; ANIMALS; BETA CATENIN; CELL LINE; CELL SURVIVAL; COSMETICS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GENE EXPRESSION; GLYCOGEN SYNTHASE KINASE 3; LEUPEPTINS; MELANINS; MICE; MICROPHTHALMIA-ASSOCIATED TRANSCRIPTION FACTOR; MONOPHENOL MONOOXYGENASE; PROPANOLAMINES; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEASOME INHIBITORS; PROTEOLYSIS; SIGNAL TRANSDUCTION;

EID: 84873058350     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-012-1530-5     Document Type: Article

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