-
1
-
-
78649603622
-
Effect of anastrozole and tamoxifen as adjuvant treatment for early-stage breast cancer: 10-year analysis of the ATAC trial
-
Cuzick J, Sestak I, Baum M, Buzdar A, Howell A, Dowsett M, Forbes JF 2010 Effect of anastrozole and tamoxifen as adjuvant treatment for early-stage breast cancer: 10-year analysis of the ATAC trial. Lancet Oncol 11:1135-1141
-
(2010)
Lancet Oncol
, vol.11
, pp. 1135-1141
-
-
Cuzick, J.1
Sestak, I.2
Baum, M.3
Buzdar, A.4
Howell, A.5
Dowsett, M.6
Forbes, J.F.7
-
2
-
-
84655162706
-
Treatment of HER2-positive breast cancer: Current status and future perspectives
-
Arteaga CL, Sliwkowski MX, Osborne CK, Perez EA, Puglisi F, Gianni L 2012 Treatment of HER2-positive breast cancer: current status and future perspectives. Nat Rev Clin Oncol 9:16-32
-
(2012)
Nat Rev Clin Oncol
, vol.9
, pp. 16-32
-
-
Arteaga, C.L.1
Sliwkowski, M.X.2
Osborne, C.K.3
Perez, E.A.4
Puglisi, F.5
Gianni, L.6
-
3
-
-
52949111533
-
Nuclear receptors and breast cancer
-
Conzen SD 2008 Nuclear receptors and breast cancer. Mol Endocrinol 22:2215-2228
-
(2008)
Mol Endocrinol
, vol.22
, pp. 2215-2228
-
-
Conzen, S.D.1
-
5
-
-
33747154772
-
Anatomical profiling of nuclear receptor expression reveals a hierarchical transcriptional network
-
Bookout AL, Jeong Y, Downes M, Yu RT, Evans RM, Mangelsdorf DJ 2006 Anatomical profiling of nuclear receptor expression reveals a hierarchical transcriptional network. Cell 126:789-799
-
(2006)
Cell
, vol.126
, pp. 789-799
-
-
Bookout, A.L.1
Jeong, Y.2
Downes, M.3
Yu, R.T.4
Evans, R.M.5
Mangelsdorf, D.J.6
-
6
-
-
77954830442
-
Expression profiling of nuclear receptors in the NCI60 cancer cell panel reveals receptor-drug and receptor-gene interactions
-
Holbeck S, Chang J, Best AM, Bookout AL, Mangelsdorf DJ, Martinez ED 2010 Expression profiling of nuclear receptors in the NCI60 cancer cell panel reveals receptor-drug and receptor-gene interactions. Mol Endocrinol 24:1287-1296
-
(2010)
Mol Endocrinol
, vol.24
, pp. 1287-1296
-
-
Holbeck, S.1
Chang, J.2
Best, A.M.3
Bookout, A.L.4
Mangelsdorf, D.J.5
Martinez, E.D.6
-
7
-
-
79951688344
-
Nr4a1 siRNA expression attenuates α-MSH regulated gene expression in 3T3-L1 adipocytes
-
Wang SC, Myers SA, Eriksson NA, Fitzsimmons RL, Muscat GE 2011 Nr4a1 siRNA expression attenuates α-MSH regulated gene expression in 3T3-L1 adipocytes. Mol Endocrinol 25:291-306
-
(2011)
Mol Endocrinol
, vol.25
, pp. 291-306
-
-
Wang, S.C.1
Myers, S.A.2
Eriksson, N.A.3
Fitzsimmons, R.L.4
Muscat, G.E.5
-
9
-
-
79952140713
-
Chicken ovalbumin upstream promoter-transcription factor II regulates nuclear receptor, myogenic, and metabolic gene expression in skeletal muscle cells
-
Crowther LM, Wang SC, Eriksson NA, Myers SA, Murray LA, Muscat GE 2011 Chicken ovalbumin upstream promoter-transcription factor II regulates nuclear receptor, myogenic, and metabolic gene expression in skeletal muscle cells. Physiol Genomics 43:213-227
-
(2011)
Physiol Genomics
, vol.43
, pp. 213-227
-
-
Crowther, L.M.1
Wang, S.C.2
Eriksson, N.A.3
Myers, S.A.4
Murray, L.A.5
Muscat, G.E.6
-
11
-
-
80755155720
-
Estrogen receptor (ESR1) mRNA expression and benefit from tamoxifen in the treatment and prevention of estrogen receptor positive breast cancer
-
Kim C, Tang G, Pogue-Geile KL, Costantino JP, Baehner FL, Baker J, Cronin MT, Watson D, Shak S, Bohn OL, Fumagalli D, Taniyama Y, Lee A, Reilly ML, Vogel VG, McCaskill-Stevens W, Ford LG, Geyer Jr CE, Wickerham DL, Wolmark N, Paik S 2011 Estrogen receptor (ESR1) mRNA expression and benefit from tamoxifen in the treatment and prevention of estrogen receptor positive breast cancer. J Clin Oncol 29:4160-4167
-
(2011)
J Clin Oncol
, vol.29
, pp. 4160-4167
-
-
Kim, C.1
Tang, G.2
Pogue-Geile, K.L.3
Costantino, J.P.4
Baehner, F.L.5
Baker, J.6
Cronin, M.T.7
Watson, D.8
Shak, S.9
Bohn, O.L.10
Fumagalli, D.11
Taniyama, Y.12
Lee, A.13
Reilly, M.L.14
Vogel, V.G.15
McCaskill-Stevens, W.16
Ford, L.G.17
Geyer Jr., C.E.18
Wickerham, D.L.19
Wolmark, N.20
Paik, S.21
more..
-
12
-
-
84855228591
-
Reconstruction of nuclear receptor network reveals that NR2E3 is a novel upstream regulator of ESR1 in breast cancer
-
Park YY, Kim K, Kim SB, Hennessy BT, Kim SM, Park ES, Lim JY, Li J, Lu Y, Gonzalez-Angulo AM, Jeong W, Mills GB, Safe S, Lee JS 2012 Reconstruction of nuclear receptor network reveals that NR2E3 is a novel upstream regulator of ESR1 in breast cancer. EMBO Mol Med 4:52-67
-
(2012)
EMBO Mol Med
, vol.4
, pp. 52-67
-
-
Park, Y.Y.1
Kim, K.2
Kim, S.B.3
Hennessy, B.T.4
Kim, S.M.5
Park, E.S.6
Lim, J.Y.7
Li, J.8
Lu, Y.9
Gonzalez-Angulo, A.M.10
Jeong, W.11
Mills, G.B.12
Safe, S.13
Lee, J.S.14
-
13
-
-
34247145491
-
Definition of clinically distinct molecular subtypes in estrogen receptorpositive breast carcinomas through genomic grade
-
Loi S, Haibe-Kains B, Desmedt C, Lallemand F, Tutt AM, Gillet C, Ellis P, Harris A, Bergh J, Foekens JA, Klijn JG, Larsimont D, Buyse M, Bontempi G, Delorenzi M, Piccart MJ, Sotiriou C 2007 Definition of clinically distinct molecular subtypes in estrogen receptorpositive breast carcinomas through genomic grade. J Clin Oncol 25:1239-1246
-
(2007)
J Clin Oncol
, vol.25
, pp. 1239-1246
-
-
Loi, S.1
Haibe-Kains, B.2
Desmedt, C.3
Lallemand, F.4
Tutt, A.M.5
Gillet, C.6
Ellis, P.7
Harris, A.8
Bergh, J.9
Foekens, J.A.10
Klijn, J.G.11
Larsimont, D.12
Buyse, M.13
Bontempi, G.14
Delorenzi, M.15
Piccart, M.J.16
Sotiriou, C.17
-
14
-
-
44949121510
-
Predicting prognosis using molecular profiling in estrogen receptor-positive breast cancer treated with tamoxifen
-
Loi S, Haibe-Kains B, Desmedt C, Wirapati P, Lallemand F, Tutt AM, Gillet C, Ellis P, Ryder K, Reid JF, Daidone MG, Pierotti MA, Berns EM, Jansen MP, Foekens JA, Delorenzi M, Bontempi G, Piccart MJ, Sotiriou C 2008 Predicting prognosis using molecular profiling in estrogen receptor-positive breast cancer treated with tamoxifen. BMC Genomics 9:239
-
(2008)
BMC Genomics
, vol.9
, pp. 239
-
-
Loi, S.1
Haibe-Kains, B.2
Desmedt, C.3
Wirapati, P.4
Lallemand, F.5
Tutt, A.M.6
Gillet, C.7
Ellis, P.8
Ryder, K.9
Reid, J.F.10
Daidone, M.G.11
Pierotti, M.A.12
Berns, E.M.13
Jansen, M.P.14
Foekens, J.A.15
Delorenzi, M.16
Bontempi, G.17
Piccart, M.J.18
Sotiriou, C.19
-
15
-
-
77955157737
-
NR4A orphan nuclear receptors: Transcriptional regulators of gene expression in metabolism and vascular biology
-
Zhao Y, Bruemmer D 2010 NR4A orphan nuclear receptors: transcriptional regulators of gene expression in metabolism and vascular biology. Arterioscler Thromb Vasc Biol 30:1535-1541
-
(2010)
Arterioscler Thromb Vasc Biol
, vol.30
, pp. 1535-1541
-
-
Zhao, Y.1
Bruemmer, D.2
-
16
-
-
77955448019
-
NR4A orphan nuclear receptors as mediators of CREB-dependent neuroprotection
-
Volakakis N, Kadkhodaei B, Joodmardi E, Wallis K, Panman L, Silvaggi J, Spiegelman BM, Perlmann T 2010 NR4A orphan nuclear receptors as mediators of CREB-dependent neuroprotection. Proc Natl Acad Sci USA 107:12317-12322
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 12317-12322
-
-
Volakakis, N.1
Kadkhodaei, B.2
Joodmardi, E.3
Wallis, K.4
Panman, L.5
Silvaggi, J.6
Spiegelman, B.M.7
Perlmann, T.8
-
17
-
-
77956295989
-
Inactivation of the orphan nuclear receptor TR3/Nur77 inhibits pancreatic cancer cell and tumor growth
-
Lee SO, Abdelrahim M, Yoon K, Chintharlapalli S, Papineni S, Kim K, Wang H, Safe S 2010 Inactivation of the orphan nuclear receptor TR3/Nur77 inhibits pancreatic cancer cell and tumor growth. Cancer Res 70:6824-6836
-
(2010)
Cancer Res
, vol.70
, pp. 6824-6836
-
-
Lee, S.O.1
Abdelrahim, M.2
Yoon, K.3
Chintharlapalli, S.4
Papineni, S.5
Kim, K.6
Wang, H.7
Safe, S.8
-
18
-
-
84862545879
-
Molecular pathways: The role of NR4A orphan nuclear receptors in cancer
-
Mohan HM, Aherne CM, Rogers AC, Baird AW, Winter DC, Murphy EP 2012 Molecular pathways: the role of NR4A orphan nuclear receptors in cancer. Clin Cancer Res 18:3223-3228
-
(2012)
Clin Cancer Res
, vol.18
, pp. 3223-3228
-
-
Mohan, H.M.1
Aherne, C.M.2
Rogers, A.C.3
Baird, A.W.4
Winter, D.C.5
Murphy, E.P.6
-
19
-
-
78650897140
-
Dissecting the transcriptional networks underlying breast cancer: NR4A1 reduces the migration of normal and breast cancer cell lines
-
Alexopoulou AN, Leao M, Caballero OL, Da Silva L, Reid L, Lakhani SR, Simpson AJ, Marshall JF, Neville AM, Jat PS 2010 Dissecting the transcriptional networks underlying breast cancer: NR4A1 reduces the migration of normal and breast cancer cell lines. Breast Cancer Res 12:R51
-
(2010)
Breast Cancer Res
, vol.12
-
-
Alexopoulou, A.N.1
Leao, M.2
Caballero, O.L.3
da Silva, L.4
Reid, L.5
Lakhani, S.R.6
Simpson, A.J.7
Marshall, J.F.8
Neville, A.M.9
Jat, P.S.10
-
20
-
-
0026758498
-
The clinical pharmacology of 6-mercaptopurine
-
Lennard L 1992 The clinical pharmacology of 6-mercaptopurine. Eur J Clin Pharmacol 43:329-339
-
(1992)
Eur J Clin Pharmacol
, vol.43
, pp. 329-339
-
-
Lennard, L.1
-
21
-
-
0029134905
-
Incidence of de-novo breast cancer in women chronically immunosuppressed after organ transplantation
-
Stewart T, Tsai SC, Grayson H, Henderson R, Opelz G 1995 Incidence of de-novo breast cancer in women chronically immunosuppressed after organ transplantation. Lancet 346:796-798
-
(1995)
Lancet
, vol.346
, pp. 796-798
-
-
Stewart, T.1
Tsai, S.C.2
Grayson, H.3
Henderson, R.4
Opelz, G.5
-
22
-
-
0037171949
-
Regulation of aromatase promoter activity in human breast tissue by nuclear receptors
-
Yang C, Yu B, Zhou D, Chen S 2002 Regulation of aromatase promoter activity in human breast tissue by nuclear receptors. Oncogene 21:2854-2863
-
(2002)
Oncogene
, vol.21
, pp. 2854-2863
-
-
Yang, C.1
Yu, B.2
Zhou, D.3
Chen, S.4
-
23
-
-
67449093629
-
Chicken ovalbumin upstream promoter transcription factor II in human breast carcinoma: Possible regulator of lymphangiogenesis via vascular endothelial growth factor-C expression
-
Nagasaki S, Suzuki T, Miki Y, Akahira J, Shibata H, Ishida T, Ohuchi N, Sasano H 2009 Chicken ovalbumin upstream promoter transcription factor II in human breast carcinoma: possible regulator of lymphangiogenesis via vascular endothelial growth factor-C expression. Cancer Sci 100:639-645
-
(2009)
Cancer Sci
, vol.100
, pp. 639-645
-
-
Nagasaki, S.1
Suzuki, T.2
Miki, Y.3
Akahira, J.4
Shibata, H.5
Ishida, T.6
Ohuchi, N.7
Sasano, H.8
-
24
-
-
33749261269
-
Immunolocalization of liver receptor homologue-1 (LRH-1) in human breast carcinoma: Possible regulator of insitu steroidogenesis
-
Miki Y, Clyne CD, Suzuki T, Moriya T, Shibuya R, Nakamura Y, Ishida T, Yabuki N, Kitada K, Hayashi S, Sasano H 2006 Immunolocalization of liver receptor homologue-1 (LRH-1) in human breast carcinoma: possible regulator of insitu steroidogenesis. Cancer Lett 244:24-33
-
(2006)
Cancer Lett
, vol.244
, pp. 24-33
-
-
Miki, Y.1
Clyne, C.D.2
Suzuki, T.3
Moriya, T.4
Shibuya, R.5
Nakamura, Y.6
Ishida, T.7
Yabuki, N.8
Kitada, K.9
Hayashi, S.10
Sasano, H.11
-
26
-
-
0037036456
-
Liver receptor homologue-1 (LRH-1) regulates expression of aromatase in preadipocytes
-
Clyne CD, Speed CJ, Zhou J, Simpson ER 2002 Liver receptor homologue-1 (LRH-1) regulates expression of aromatase in preadipocytes. J Biol Chem 277:20591-20597
-
(2002)
J Biol Chem
, vol.277
, pp. 20591-20597
-
-
Clyne, C.D.1
Speed, C.J.2
Zhou, J.3
Simpson, E.R.4
-
27
-
-
79958193092
-
The liver receptor homolog-1 regulates estrogen receptor expression in breast cancer cells
-
Thiruchelvam PT, Lai CF, Hua H, Thomas RS, Hurtado A, Hudson W, Bayly AR, Kyle FJ, Periyasamy M, Photiou A, Spivey AC, Ortlund EA, Whitby RJ, Carroll JS, Coombes RC, Buluwela L, Ali S 2011 The liver receptor homolog-1 regulates estrogen receptor expression in breast cancer cells. Breast Cancer Res Treat 127:385-396
-
(2011)
Breast Cancer Res Treat
, vol.127
, pp. 385-396
-
-
Thiruchelvam, P.T.1
Lai, C.F.2
Hua, H.3
Thomas, R.S.4
Hurtado, A.5
Hudson, W.6
Bayly, A.R.7
Kyle, F.J.8
Periyasamy, M.9
Photiou, A.10
Spivey, A.C.11
Ortlund, E.A.12
Whitby, R.J.13
Carroll, J.S.14
Coombes, R.C.15
Buluwela, L.16
Ali, S.17
-
28
-
-
28744459007
-
The nuclear receptor liver receptor homolog-1 is an estrogen receptor target gene
-
Annicotte JS, Chavey C, Servant N, Teyssier J, Bardin A, Licznar A, Badia E, Pujol P, Vignon F, Maudelonde T, Lazennec G, Cavailles V, Fajas L 2005 The nuclear receptor liver receptor homolog-1 is an estrogen receptor target gene. Oncogene 24:8167-8175
-
(2005)
Oncogene
, vol.24
, pp. 8167-8175
-
-
Annicotte, J.S.1
Chavey, C.2
Servant, N.3
Teyssier, J.4
Bardin, A.5
Licznar, A.6
Badia, E.7
Pujol, P.8
Vignon, F.9
Maudelonde, T.10
Lazennec, G.11
Cavailles, V.12
Fajas, L.13
-
29
-
-
0036531824
-
Biallelic inactivation of the thyroid hormone receptor beta1 gene in early stage breast cancer
-
Li Z, Meng ZH, Chandrasekaran R, Kuo WL, Collins CC, Gray JW, Dairkee SH 2002 Biallelic inactivation of the thyroid hormone receptor beta1 gene in early stage breast cancer. Cancer Res 62:1939-1943
-
(2002)
Cancer Res
, vol.62
, pp. 1939-1943
-
-
Li, Z.1
Meng, Z.H.2
Chandrasekaran, R.3
Kuo, W.L.4
Collins, C.C.5
Gray, J.W.6
Dairkee, S.H.7
-
30
-
-
71649086659
-
Aberrant methylation of the THRB gene in tissue and plasma of breast cancer patients
-
Ling Y, Xu X, Hao J, Ling X, Du X, Liu X, Zhao X 2010 Aberrant methylation of the THRB gene in tissue and plasma of breast cancer patients. Cancer Genet Cytogenet 196:140-145
-
(2010)
Cancer Genet Cytogenet
, vol.196
, pp. 140-145
-
-
Ling, Y.1
Xu, X.2
Hao, J.3
Ling, X.4
Du, X.5
Liu, X.6
Zhao, X.7
-
31
-
-
79251648045
-
The sodium iodide symporter (NIS) and potential regulators in normal, benign and malignant human breast tissue
-
Ryan J, Curran CE, Hennessy E, Newell J, Morris JC, Kerin MJ, Dwyer RM 2011 The sodium iodide symporter (NIS) and potential regulators in normal, benign and malignant human breast tissue. PLoS One 6:e16023
-
(2011)
PLoS One
, vol.6
-
-
Ryan, J.1
Curran, C.E.2
Hennessy, E.3
Newell, J.4
Morris, J.C.5
Kerin, M.J.6
Dwyer, R.M.7
-
32
-
-
0037142618
-
Expression of thyroid hormone receptor/erbA genes is altered in human breast cancer
-
Silva JM, Domínguez G, González-Sancho JM, García JM, Silva J, García-Andrade C, Navarro A, Muñoz A, Bonilla F 2002 Expression of thyroid hormone receptor/erbA genes is altered in human breast cancer. Oncogene 21:4307-4316
-
(2002)
Oncogene
, vol.21
, pp. 4307-4316
-
-
Silva, J.M.1
Domínguez, G.2
González-Sancho, J.M.3
García, J.M.4
Silva, J.5
García-Andrade, C.6
Navarro, A.7
Muñoz, A.8
Bonilla, F.9
-
33
-
-
79960844326
-
Mutation of thyroid hormone receptor-beta in mice predisposes to the development of mammary tumors
-
Guigon CJ, Kim DW, Willingham MC, Cheng SY 2011 Mutation of thyroid hormone receptor-beta in mice predisposes to the development of mammary tumors. Oncogene 30:3381-3390
-
(2011)
Oncogene
, vol.30
, pp. 3381-3390
-
-
Guigon, C.J.1
Kim, D.W.2
Willingham, M.C.3
Cheng, S.Y.4
-
34
-
-
0343851616
-
The orphan nuclear receptor Ear-2 is a negative coregulator for thyroid hormone nuclear receptor function
-
Zhu XG, Park KS, Kaneshige M, Bhat MK, Zhu Q, Mariash CN, McPhie P, Cheng SY 2000 The orphan nuclear receptor Ear-2 is a negative coregulator for thyroid hormone nuclear receptor function. Mol Cell Biol 20:2604-2618
-
(2000)
Mol Cell Biol
, vol.20
, pp. 2604-2618
-
-
Zhu, X.G.1
Park, K.S.2
Kaneshige, M.3
Bhat, M.K.4
Zhu, Q.5
Mariash, C.N.6
McPhie, P.7
Cheng, S.Y.8
-
35
-
-
13244255740
-
PPARγ expression in breast cancer: Clinical value and correlation with ERβ
-
Papadaki I, Mylona E, Giannopoulou I, Markaki S, Keramopoulos A, Nakopoulou L 2005 PPARγ expression in breast cancer: clinical value and correlation with ERβ. Histopathology 46:37-42
-
(2005)
Histopathology
, vol.46
, pp. 37-42
-
-
Papadaki, I.1
Mylona, E.2
Giannopoulou, I.3
Markaki, S.4
Keramopoulos, A.5
Nakopoulou, L.6
-
36
-
-
0037899628
-
Use of the peroxisome proliferator-activated receptor (PPAR) γ ligand troglitazone as treatment for refractory breast cancer: A phase II study
-
Burstein HJ, Demetri GD, Mueller E, Sarraf P, Spiegelman BM, Winer EP 2003 Use of the peroxisome proliferator-activated receptor (PPAR) γ ligand troglitazone as treatment for refractory breast cancer: a phase II study. Breast Cancer Res Treat 79:391-397
-
(2003)
Breast Cancer Res Treat
, vol.79
, pp. 391-397
-
-
Burstein, H.J.1
Demetri, G.D.2
Mueller, E.3
Sarraf, P.4
Spiegelman, B.M.5
Winer, E.P.6
-
37
-
-
21244432740
-
Peroxisome proliferator-activated receptor-γ ligands for the treatment of breast cancer
-
Fenner MH, Elstner E 2005 Peroxisome proliferator-activated receptor-γ ligands for the treatment of breast cancer. Expert Opin Investig Drugs 14:557-568
-
(2005)
Expert Opin Investig Drugs
, vol.14
, pp. 557-568
-
-
Fenner, M.H.1
Elstner, E.2
-
38
-
-
6444241108
-
Can PPARγ ligands be used in cancer therapy?
-
Rumi MA, Ishihara S, Kazumori H, Kadowaki Y, Kinoshita Y 2004 Can PPARγ ligands be used in cancer therapy? Curr Med Chem Anticancer Agents 4:465-477
-
(2004)
Curr Med Chem Anticancer Agents
, vol.4
, pp. 465-477
-
-
Rumi, M.A.1
Ishihara, S.2
Kazumori, H.3
Kadowaki, Y.4
Kinoshita, Y.5
-
40
-
-
33646361583
-
GenePattern 2.0
-
Reich M, Liefeld T, Gould J, Lerner J, Tamayo P, Mesirov JP 2006 GenePattern 2.0. Nat Genet 38:500-501
-
(2006)
Nat Genet
, vol.38
, pp. 500-501
-
-
Reich, M.1
Liefeld, T.2
Gould, J.3
Lerner, J.4
Tamayo, P.5
Mesirov, J.P.6
|