메뉴 건너뛰기




Volumn 6, Issue 1, 2011, Pages

The sodium iodide Symporter (NIS) and potential regulators in normal, benign and malignant human breast tissue

Author keywords

[No Author keywords available]

Indexed keywords

ESTRADIOL; ESTROGEN RECEPTOR ALPHA; PHOSPHATIDYLINOSITOL 3 KINASE; RETINOIC ACID; RETINOIC ACID RECEPTOR ALPHA; RETINOIC ACID RECEPTOR BETA; RNA; SODIUM IODIDE SYMPORTER; THYROID HORMONE; THYROID HORMONE RECEPTOR ALPHA; THYROID HORMONE RECEPTOR BETA; THYROXINE; COTRANSPORTER;

EID: 79251648045     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0016023     Document Type: Article
Times cited : (30)

References (35)
  • 1
    • 0037326161 scopus 로고    scopus 로고
    • The sodium/iodide Symporter (NIS): Characterization, regulation, and medical significance
    • Dohán O, De la Vieja A, Paroder V, Riedel C, Artani M, et al. (2003) The sodium/iodide Symporter (NIS): characterization, regulation, and medical significance. Endocr Rev 24: 48-77.
    • (2003) Endocr Rev , vol.24 , pp. 48-77
    • Dohán, O.1    de la Vieja, A.2    Paroder, V.3    Riedel, C.4    Artani, M.5
  • 2
    • 0033835541 scopus 로고    scopus 로고
    • The mammary gland iodide transporter is expressed during lactation and in breast cancer
    • Tazebay U, Wapnir I, Levy O, Dohan O, Zuckier L, et al. (2000) The mammary gland iodide transporter is expressed during lactation and in breast cancer. Nat Med 6: 871-878.
    • (2000) Nat Med , vol.6 , pp. 871-878
    • Tazebay, U.1    Wapnir, I.2    Levy, O.3    Dohan, O.4    Zuckier, L.5
  • 3
    • 0034453762 scopus 로고    scopus 로고
    • Tissue iodine content and serum-mediated 125I uptake-blocking activity in breast cancer
    • Kilbane M, Ajjan R, Weetman A, Dwyer R, McDermott E, et al. (2000) Tissue iodine content and serum-mediated 125I uptake-blocking activity in breast cancer. J Clin Endocrinol Metab 85: 1245-1250.
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 1245-1250
    • Kilbane, M.1    Ajjan, R.2    Weetman, A.3    Dwyer, R.4    McDermott, E.5
  • 4
    • 0037278323 scopus 로고    scopus 로고
    • Functional expression of sodium iodide symporter (NIS) in human breast cancer tissue
    • Upadhyay G, Singh R, Agarwal G, Mishra S, Pal L, et al. (2003) Functional expression of sodium iodide symporter (NIS) in human breast cancer tissue. Breast Cancer Res Treat 77: 157-165.
    • (2003) Breast Cancer Res Treat , vol.77 , pp. 157-165
    • Upadhyay, G.1    Singh, R.2    Agarwal, G.3    Mishra, S.4    Pal, L.5
  • 6
    • 0037683589 scopus 로고    scopus 로고
    • Immunohistochemical profile of the sodium/iodide symporter in thyroid, breast, and other carcinomas using high density tissue microarrays and conventional sections
    • Wapnir I, van de Rijn M, Nowels K, Amenta P, Walton K, et al. (2003) Immunohistochemical profile of the sodium/iodide symporter in thyroid, breast, and other carcinomas using high density tissue microarrays and conventional sections. J Clin Endocrinol Metab 88: 1880-1888.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 1880-1888
    • Wapnir, I.1    van de Rijn, M.2    Nowels, K.3    Amenta, P.4    Walton, K.5
  • 7
    • 62149129345 scopus 로고    scopus 로고
    • Endogenous NIS expression in triple-negative breast cancers
    • Renier C, Yao C, Goris M, Ghosh M, Katznelson L, et al. (2009) Endogenous NIS expression in triple-negative breast cancers. Ann Surg Oncol 16: 962-968.
    • (2009) Ann Surg Oncol , vol.16 , pp. 962-968
    • Renier, C.1    Yao, C.2    Goris, M.3    Ghosh, M.4    Katznelson, L.5
  • 8
    • 0035487238 scopus 로고    scopus 로고
    • Correlation between 99mTc-pertechnetate uptakes and expressions of human sodium iodide symporter gene in breast tumor tissues
    • Moon D, Lee S, Park K, Park K, Ahn S, et al. (2001) Correlation between 99mTc-pertechnetate uptakes and expressions of human sodium iodide symporter gene in breast tumor tissues. Nucl Med Biol 28: 829-834.
    • (2001) Nucl Med Biol , vol.28 , pp. 829-834
    • Moon, D.1    Lee, S.2    Park, K.3    Park, K.4    Ahn, S.5
  • 9
    • 3042811612 scopus 로고    scopus 로고
    • The Na+/I2 symporter mediates iodide uptake in breast cancer metastases and can be selectively down-regulated in the thyroid
    • Wapnir I, Goris M, Yudd A, Dohan O, Adelman D, et al. (2004) The Na+/I2 symporter mediates iodide uptake in breast cancer metastases and can be selectively down-regulated in the thyroid. Clin Cancer Res 10: 4294-4302.
    • (2004) Clin Cancer Res , vol.10 , pp. 4294-4302
    • Wapnir, I.1    Goris, M.2    Yudd, A.3    Dohan, O.4    Adelman, D.5
  • 10
    • 75049083184 scopus 로고    scopus 로고
    • Breast cancer brain metastases express the sodium iodide symporter
    • Renier C, Vogel H, Offor O, Yao C, Wapnir I (2010) Breast cancer brain metastases express the sodium iodide symporter. J Neurooncol 96: 331-336.
    • (2010) J Neurooncol , vol.96 , pp. 331-336
    • Renier, C.1    Vogel, H.2    Offor, O.3    Yao, C.4    Wapnir, I.5
  • 11
    • 33748799401 scopus 로고    scopus 로고
    • Mammary radioiodine accumulation due to functional sodium iodide symporter expression in a benign fibroadenoma
    • Berger F, Unterholzner S, Diebold J, Knesewitsch P, Hahn K, et al. (2006) Mammary radioiodine accumulation due to functional sodium iodide symporter expression in a benign fibroadenoma. Biochem Biophys Res Commun 349: 1258-1263.
    • (2006) Biochem Biophys Res Commun , vol.349 , pp. 1258-1263
    • Berger, F.1    Unterholzner, S.2    Diebold, J.3    Knesewitsch, P.4    Hahn, K.5
  • 12
    • 78650988085 scopus 로고    scopus 로고
    • Stimulation of retinoic acid-induced functional sodium iodide symporter (NIS) expression and cytotoxicity of (131)I by carbamazepine in breast cancer cells
    • Willhauck MJ, DJ OK, Wunderlich N, Goke B, Spitzweg C (2011) Stimulation of retinoic acid-induced functional sodium iodide symporter (NIS) expression and cytotoxicity of (131)I by carbamazepine in breast cancer cells. Breast Cancer Res Treat 125: 377-386.
    • (2011) Breast Cancer Res Treat , vol.125 , pp. 377-386
    • Willhauck, M.J.D.J.O.K.1    Wunderlich, N.2    Goke, B.3    Spitzweg, C.4
  • 13
    • 43149109505 scopus 로고    scopus 로고
    • Functional sodium iodide symporter expression in breast cancer xenografts in vivo after systemic treatment with retinoic acid and dexamethasone
    • Willhauck M, Sharif-Samani B, Senekowitsch-Schmidtke R, Wunderlich N, Göke B, et al. (2008) Functional sodium iodide symporter expression in breast cancer xenografts in vivo after systemic treatment with retinoic acid and dexamethasone. Breast Cancer Res Treat 109: 263-272.
    • (2008) Breast Cancer Res Treat , vol.109 , pp. 263-272
    • Willhauck, M.1    Sharif-Samani, B.2    Senekowitsch-Schmidtke, R.3    Wunderlich, N.4    Göke, B.5
  • 14
    • 33750269612 scopus 로고    scopus 로고
    • A perspective view of sodium iodide symporter research and its clinical implications
    • Riesco-Eizaguirre G, Santisteban P (2006) A perspective view of sodium iodide symporter research and its clinical implications. Eur J Endocrinol 155: 495-512.
    • (2006) Eur J Endocrinol , vol.155 , pp. 495-512
    • Riesco-Eizaguirre, G.1    Santisteban, P.2
  • 15
    • 13144267690 scopus 로고    scopus 로고
    • Autoregulation of thyroid-specific gene transcription by thyroglobulin
    • Suzuki K, Lavaroni S, Mori A, Ohta M, Saito J, et al. (1998) Autoregulation of thyroid-specific gene transcription by thyroglobulin. Proc Natl Acad Sci U S A 95: 8251-8256.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 8251-8256
    • Suzuki, K.1    Lavaroni, S.2    Mori, A.3    Ohta, M.4    Saito, J.5
  • 16
    • 0033303687 scopus 로고    scopus 로고
    • Follicular thyroglobulin suppresses iodide uptake by suppressing expression of the sodium/ iodide symporter gene
    • Suzuki K, Mori A, Saito J, Moriyama E, Ullianich L, et al. (1999) Follicular thyroglobulin suppresses iodide uptake by suppressing expression of the sodium/ iodide symporter gene. Endocrinology 140: 5422-5430.
    • (1999) Endocrinology , vol.140 , pp. 5422-5430
    • Suzuki, K.1    Mori, A.2    Saito, J.3    Moriyama, E.4    Ullianich, L.5
  • 17
    • 22144497430 scopus 로고    scopus 로고
    • Differential regulation of sodium/iodide symporter gene expression by nuclear receptor ligands in MCF-7 breast cancer cells
    • Kogai T, Kanamoto Y, Li A, Che L, Ohashi E, et al. (2005) Differential regulation of sodium/iodide symporter gene expression by nuclear receptor ligands in MCF-7 breast cancer cells. Endocrinology 146: 3059-3069.
    • (2005) Endocrinology , vol.146 , pp. 3059-3069
    • Kogai, T.1    Kanamoto, Y.2    Li, A.3    Che, L.4    Ohashi, E.5
  • 18
    • 33744519038 scopus 로고    scopus 로고
    • Unliganded estrogen receptor-alpha activates transcription of the mammary gland Na+/I2 symporter gene
    • Alotaibi H, Yaman E, Demirpençe E, Tazebay U (2006) Unliganded estrogen receptor-alpha activates transcription of the mammary gland Na+/I2 symporter gene. Biochem Biophys Res Commun 345: 1487-1496.
    • (2006) Biochem Biophys Res Commun , vol.345 , pp. 1487-1496
    • Alotaibi, H.1    Yaman, E.2    Demirpençe, E.3    Tazebay, U.4
  • 19
    • 6344260196 scopus 로고    scopus 로고
    • Signaling through 39,59-cyclic adenosine monophosphate and phosphoinositide-3 kinase induces sodium/iodide symporter expression in breast cancer
    • Knostman K, Cho J, Ryu K, Lin X, McCubrey J, et al. (2004) Signaling through 39,59-cyclic adenosine monophosphate and phosphoinositide-3 kinase induces sodium/iodide symporter expression in breast cancer. J Clin Endocrinol Metab 89: 5196-5203.
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 5196-5203
    • Knostman, K.1    Cho, J.2    Ryu, K.3    Lin, X.4    McCubrey, J.5
  • 20
    • 34548389433 scopus 로고    scopus 로고
    • PI3K activation is associated with intracellular sodium/iodide symporter protein expression in breast cancer
    • Knostman K, McCubrey J, Morrison C, Zhang Z, Capen C, et al. (2007) PI3K activation is associated with intracellular sodium/iodide symporter protein expression in breast cancer. BMC Cancer 7: 137.
    • (2007) BMC Cancer , vol.7 , pp. 137
    • Knostman, K.1    McCubrey, J.2    Morrison, C.3    Zhang, Z.4    Capen, C.5
  • 21
    • 58349109708 scopus 로고    scopus 로고
    • Thyroid hormone receptor beta1 acts as a potent suppressor of tumor invasiveness and metastasis
    • Martínez-Iglesias O, Garcia-Silva S, Tenbaum S, Regadera J, Larcher F, et al. (2009) Thyroid hormone receptor beta1 acts as a potent suppressor of tumor invasiveness and metastasis. Cancer Res 69: 501-509.
    • (2009) Cancer Res , vol.69 , pp. 501-509
    • Martínez-Iglesias, O.1    Garcia-Silva, S.2    Tenbaum, S.3    Regadera, J.4    Larcher, F.5
  • 22
    • 0037142618 scopus 로고    scopus 로고
    • Expression of thyroid hormone receptor/erbA genes is altered in human breast cancer
    • Silva J, Domínguez G, González-Sancho J, García J, Silva J, et al. (2002) Expression of thyroid hormone receptor/erbA genes is altered in human breast cancer. Oncogene 21: 4307-4316.
    • (2002) Oncogene , vol.21 , pp. 4307-4316
    • Silva, J.1    Domínguez, G.2    González-Sancho, J.3    García, J.4    Silva, J.5
  • 23
    • 29844453468 scopus 로고    scopus 로고
    • Influence of thyroid hormone receptors on breast cancer cell proliferation
    • Conde I, Paniagua R, Zamora J, Blánquez M, Fraile B, et al. (2006) Influence of thyroid hormone receptors on breast cancer cell proliferation. Ann Oncol 17: 60-64.
    • (2006) Ann Oncol , vol.17 , pp. 60-64
    • Conde, I.1    Paniagua, R.2    Zamora, J.3    Blánquez, M.4    Fraile, B.5
  • 24
    • 38349106695 scopus 로고    scopus 로고
    • Evaluation and validation of candidate endogenous control genes for real-time quantitative PCR studies of breast cancer
    • McNeill R, Miller N, Kerin M (2007) Evaluation and validation of candidate endogenous control genes for real-time quantitative PCR studies of breast cancer. BMC Mol Biol 8: 107.
    • (2007) BMC Mol Biol , vol.8 , pp. 107
    • McNeill, R.1    Miller, N.2    Kerin, M.3
  • 25
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(2Delta Delta C(T)) Method
    • Livak K, Schmittgen T (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(2Delta Delta C(T)) Method. Methods 25: 402-408.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.1    Schmittgen, T.2
  • 26
    • 0033328137 scopus 로고    scopus 로고
    • Development of monoclonal antibodies against the human sodium iodide symporter: Immunohistochemical characterization of this protein in thyroid cells
    • Castro M, Bergert E, Beito T, McIver B, Goellner J, et al. (1999) Development of monoclonal antibodies against the human sodium iodide symporter: immunohistochemical characterization of this protein in thyroid cells. J Clin Endocrinol Metab 84: 2957-2962.
    • (1999) J Clin Endocrinol Metab , vol.84 , pp. 2957-2962
    • Castro, M.1    Bergert, E.2    Beito, T.3    McIver, B.4    Goellner, J.5
  • 27
    • 1242341401 scopus 로고    scopus 로고
    • Advances in Na(+)/I(2) symporter (NIS) research in the thyroid and beyond
    • Dohán O, Carrasco N (2003) Advances in Na(+)/I(2) symporter (NIS) research in the thyroid and beyond. Mol Cell Endocrinol 213: 59-70.
    • (2003) Mol Cell Endocrinol , vol.213 , pp. 59-70
    • Dohán, O.1    Carrasco, N.2
  • 28
    • 77953689913 scopus 로고    scopus 로고
    • Intronic elements in the Na+/I2 symporter gene (NIS) interact with retinoic acid receptors and mediate initiation of transcription
    • Alotaibi H, Yaman E, Salvatore D, Di Dato V, Telkoparan P, et al. (2010) Intronic elements in the Na+/I2 symporter gene (NIS) interact with retinoic acid receptors and mediate initiation of transcription. Nucleic Acids Res 38: 3172-3185.
    • (2010) Nucleic Acids Res , vol.38 , pp. 3172-3185
    • Alotaibi, H.1    Yaman, E.2    Salvatore, D.3    di Dato, V.4    Telkoparan, P.5
  • 29
    • 65949124481 scopus 로고    scopus 로고
    • Activation of the PI3 kinase pathway by retinoic acid mediates sodium/iodide symporter induction and iodide transport in MCF-7 breast cancer cells
    • Ohashi E, Kogai T, Kagechika H, Brent G (2009) Activation of the PI3 kinase pathway by retinoic acid mediates sodium/iodide symporter induction and iodide transport in MCF-7 breast cancer cells. Cancer Res 69: 3443-3450.
    • (2009) Cancer Res , vol.69 , pp. 3443-3450
    • Ohashi, E.1    Kogai, T.2    Kagechika, H.3    Brent, G.4
  • 30
    • 27944440173 scopus 로고    scopus 로고
    • Altered gene expression profiles by sodium/iodide symporter gene transfection in a human anaplastic thyroid carcinoma cell line using a radioactive complementary DNA microarray
    • Gol Choe J, Kim Y, Kim K, Choo H, Shin J, et al. (2005) Altered gene expression profiles by sodium/iodide symporter gene transfection in a human anaplastic thyroid carcinoma cell line using a radioactive complementary DNA microarray. Nucl Med Commun 26: 1155-1162.
    • (2005) Nucl Med Commun , vol.26 , pp. 1155-1162
    • Gol Choe, J.1    Kim, Y.2    Kim, K.3    Choo, H.4    Shin, J.5
  • 31
    • 27744560391 scopus 로고    scopus 로고
    • Antimetastatic gene expression profiles mediated by retinoic acid receptor beta 2 in MDA-MB-435 breast cancer cells
    • Wallden B, Emond M, Swift M, Disis M, Swisshelm K (2005) Antimetastatic gene expression profiles mediated by retinoic acid receptor beta 2 in MDA-MB-435 breast cancer cells. BMC Cancer 5: 140.
    • (2005) BMC Cancer , vol.5 , pp. 140
    • Wallden, B.1    Emond, M.2    Swift, M.3    Disis, M.4    Swisshelm, K.5
  • 32
    • 0036129545 scopus 로고    scopus 로고
    • The association of benign and malignant ovarian adenofibromas with breast cancer and thyroid disorders
    • Silva E, Tornos C, Malpica A, Deavers M, Tortolero-Luna G, et al. (2002) The association of benign and malignant ovarian adenofibromas with breast cancer and thyroid disorders. Int J Surg Pathol 10: 33-39.
    • (2002) Int J Surg Pathol , vol.10 , pp. 33-39
    • Silva, E.1    Tornos, C.2    Malpica, A.3    Deavers, M.4    Tortolero-Luna, G.5
  • 33
    • 0027324301 scopus 로고
    • Thyroid hormone receptor dimerization is required for dominant negative inhibition by mutations that cause thyroid hormone resistance
    • Nagaya T, Jameson J (1993) Thyroid hormone receptor dimerization is required for dominant negative inhibition by mutations that cause thyroid hormone resistance. J Biol Chem 268: 15766-15771.
    • (1993) J Biol Chem , vol.268 , pp. 15766-15771
    • Nagaya, T.1    Jameson, J.2
  • 34
    • 15444378492 scopus 로고    scopus 로고
    • Heterodimers of retinoic acid receptors and thyroid hormone receptors display unique combinatorial regulatory properties
    • Lee S, Privalsky M (2005) Heterodimers of retinoic acid receptors and thyroid hormone receptors display unique combinatorial regulatory properties. Mol Endocrinol 19: 863-878.
    • (2005) Mol Endocrinol , vol.19 , pp. 863-878
    • Lee, S.1    Privalsky, M.2
  • 35
    • 54749122110 scopus 로고    scopus 로고
    • Phase I study of noninvasive imaging of adenovirus-mediated gene expression in the human prostate
    • Barton KN, Stricker H, Brown SL, Elshaikh M, Aref I, et al. (2008) Phase I study of noninvasive imaging of adenovirus-mediated gene expression in the human prostate. Mol Ther 16: 1761-1769.
    • (2008) Mol Ther , vol.16 , pp. 1761-1769
    • Barton, K.N.1    Stricker, H.2    Brown, S.L.3    Elshaikh, M.4    Aref, I.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.