A novel two-step QSAR modeling work flow to predict selectivity and activity of HDAC inhibitors

Bioorganic and Medicinal Chemistry Letters

Volumn 23, Issue 4, 2013, Pages 929-933

  Zhao, Lingling ^a   Xiang, Yuhong ^a   Song, Jinglin ^a   Zhang, Zhuoyong ^a  

^a CAPITAL NORMAL UNIVERSITY   (China)

Author keywords

GA kNN; HDAC; Predict activity; QSAR; Two step

Indexed keywords

HISTONE DEACETYLASE 1; HISTONE DEACETYLASE 6; HISTONE DEACETYLASE INHIBITOR;

ARTICLE; DRUG ACTIVITY; DRUG SCREENING; DRUG SELECTIVITY; DRUG STRUCTURE; PREDICTIVE VALUE; QUANTITATIVE STRUCTURE ACTIVITY RELATION; VALIDATION STUDY; WORKFLOW;

HISTONE DEACETYLASE INHIBITORS; HUMANS; MODELS, CHEMICAL; MODELS, MOLECULAR; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; WORKFLOW;

EID: 84872927507     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2012.12.067     Document Type: Article

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