메뉴 건너뛰기




Volumn 40, Issue 2, 2013, Pages 295-303

Development and automation of a novel NET-PET tracer: [11C]Me@APPI

Author keywords

Carbon 11; Me@APPI; Noradrenaline; PET; Radiosynthesis; Transporter

Indexed keywords

1 [3 (METHYLAMINO) 1 PHENYLPROPYL] 3 PHENYL 1H BENZO[D]IMIDAZOL 2(3H)ONE C 11; DOPAMINE TRANSPORTER; NORADRENALIN TRANSPORTER; SEROTONIN TRANSPORTER; TRACER; UNCLASSIFIED DRUG;

EID: 84872893422     PISSN: 09698051     EISSN: 18729614     Source Type: Journal    
DOI: 10.1016/j.nucmedbio.2012.11.009     Document Type: Article
Times cited : (10)

References (34)
  • 1
    • 13544263446 scopus 로고    scopus 로고
    • Norepinephrine transporter inhibitors and their therapeutic potential
    • Zhou J. Norepinephrine transporter inhibitors and their therapeutic potential. Drugs Future 2004, 29:1235-1244.
    • (2004) Drugs Future , vol.29 , pp. 1235-1244
    • Zhou, J.1
  • 2
    • 16944362115 scopus 로고    scopus 로고
    • Reduced levels of norepinephrine transporters in the locus coeruleus in major depression
    • Klimek V., Stockmeier C.A., Overholser J., Meltzer H.Y., Kalka S., Dilley G., et al. Reduced levels of norepinephrine transporters in the locus coeruleus in major depression. J Neurosci 1997, 17:8451-8458.
    • (1997) J Neurosci , vol.17 , pp. 8451-8458
    • Klimek, V.1    Stockmeier, C.A.2    Overholser, J.3    Meltzer, H.Y.4    Kalka, S.5    Dilley, G.6
  • 3
    • 0033232510 scopus 로고    scopus 로고
    • Role of norepinephrine in the pathophysiology and treatment of mood disorders
    • Ressler K.J., Nemeroff C.B. Role of norepinephrine in the pathophysiology and treatment of mood disorders. Biol Psychiatry 1999, 46:1219-1233.
    • (1999) Biol Psychiatry , vol.46 , pp. 1219-1233
    • Ressler, K.J.1    Nemeroff, C.B.2
  • 4
    • 0031054886 scopus 로고    scopus 로고
    • Pharmacology and distribution of norepinephrine transporters in the human locus coeruleus and raphe nuclei
    • Ordway G.A., Stockmeier C.A., Cason G.W., Klimek V. Pharmacology and distribution of norepinephrine transporters in the human locus coeruleus and raphe nuclei. J Neurosci 1997, 17:1710-1719.
    • (1997) J Neurosci , vol.17 , pp. 1710-1719
    • Ordway, G.A.1    Stockmeier, C.A.2    Cason, G.W.3    Klimek, V.4
  • 5
    • 77952292091 scopus 로고    scopus 로고
    • The norepinephrine transporter (NET) radioligand (S, S)-[18F]FMeNER-D2 shows significant decreases in NET density in the human brain in Alzheimer's disease: A post-mortem autoradiographic study
    • Gulyás B, Brockschnieder D, Nag S, Pavlova E, Kása P, Beliczai Z, et al. The norepinephrine transporter (NET) radioligand (S, S)-[18F]FMeNER-D2 shows significant decreases in NET density in the human brain in Alzheimer's disease: A post-mortem autoradiographic study. Neurochem Int 56:789-98.
    • Neurochem Int , vol.56 , pp. 789-98
    • Gulyás, B.1    Brockschnieder, D.2    Nag, S.3    Pavlova, E.4    Kása, P.5    Beliczai, Z.6
  • 6
    • 14844313683 scopus 로고    scopus 로고
    • Norepinephrine transporter immunoblotting and radioligand binding in cocaine abusers
    • Mash D.C., Ouyang Q., Qin Y., Pablo J. Norepinephrine transporter immunoblotting and radioligand binding in cocaine abusers. J Neurosci Methods 2005, 143:79-85.
    • (2005) J Neurosci Methods , vol.143 , pp. 79-85
    • Mash, D.C.1    Ouyang, Q.2    Qin, Y.3    Pablo, J.4
  • 7
    • 32844473787 scopus 로고    scopus 로고
    • Distribution of norepinephrine transporters in the non-human primate brain
    • Smith H.R., Beveridge T.J.R., Porrino L.J. Distribution of norepinephrine transporters in the non-human primate brain. Neuroscience 2006, 138:703-714.
    • (2006) Neuroscience , vol.138 , pp. 703-714
    • Smith, H.R.1    Beveridge, T.J.R.2    Porrino, L.J.3
  • 8
    • 34547851802 scopus 로고    scopus 로고
    • Imaging the norepinephrine transporter in humans with (S, S)-[11C]O-methyl reboxetine and PET: problems and progress
    • Logan J., Wang G.-j., Telang F., Fowler J.S., Alexoff D., Zabroski J., et al. Imaging the norepinephrine transporter in humans with (S, S)-[11C]O-methyl reboxetine and PET: problems and progress. Nucl Med Biol 2007, 34:667-679.
    • (2007) Nucl Med Biol , vol.34 , pp. 667-679
    • Logan, J.1    Wang, G.-J.2    Telang, F.3    Fowler, J.S.4    Alexoff, D.5    Zabroski, J.6
  • 9
    • 0025968249 scopus 로고
    • Distribution of catecholamine uptake sites in human brain as determined by quantitative [3H] mazindol autoradiography
    • Donnan G.A., Kaczmarczyk S.J., Paxinos G., Chilco P.J., Kalnins R.M., Woodhouse D.G., et al. Distribution of catecholamine uptake sites in human brain as determined by quantitative [3H] mazindol autoradiography. J Comp Neurol 1991, 304:419-434.
    • (1991) J Comp Neurol , vol.304 , pp. 419-434
    • Donnan, G.A.1    Kaczmarczyk, S.J.2    Paxinos, G.3    Chilco, P.J.4    Kalnins, R.M.5    Woodhouse, D.G.6
  • 10
    • 0029067190 scopus 로고
    • Carbon-11-FLB 457: a radioligand for extrastriatal D2 dopamine receptors
    • Halldin C., Farde L., Högberg T., Mohell N., Hall H., Suhara T., et al. Carbon-11-FLB 457: a radioligand for extrastriatal D2 dopamine receptors. J Nucl Med 1995, 36:1275-1281.
    • (1995) J Nucl Med , vol.36 , pp. 1275-1281
    • Halldin, C.1    Farde, L.2    Högberg, T.3    Mohell, N.4    Hall, H.5    Suhara, T.6
  • 11
    • 0034966465 scopus 로고    scopus 로고
    • [11C]Cocaine: PET studies of cocaine pharmacokinetics, dopamine transporter availability and dopamine transporter occupancy
    • Fowler J.S., Volkow N.D., Wang G.J., Gatley S.J., Logan J. [11C]Cocaine: PET studies of cocaine pharmacokinetics, dopamine transporter availability and dopamine transporter occupancy. Nucl Med Biol 2001, 28:561-572.
    • (2001) Nucl Med Biol , vol.28 , pp. 561-572
    • Fowler, J.S.1    Volkow, N.D.2    Wang, G.J.3    Gatley, S.J.4    Logan, J.5
  • 12
    • 0028120970 scopus 로고
    • Pharmacological heterogeneity of the cloned and native human dopamine transporter: disassociation of [3H]WIN 35,428 and [3H]GBR 12,935 binding
    • Pristupa Z.B., Wilson J.M., Hoffman B.J., Kish S.J., Niznik H.B. Pharmacological heterogeneity of the cloned and native human dopamine transporter: disassociation of [3H]WIN 35,428 and [3H]GBR 12,935 binding. Mol Pharmacol 1994, 45:125-135.
    • (1994) Mol Pharmacol , vol.45 , pp. 125-135
    • Pristupa, Z.B.1    Wilson, J.M.2    Hoffman, B.J.3    Kish, S.J.4    Niznik, H.B.5
  • 13
    • 0026610297 scopus 로고
    • [3H]nisoxetine: a radioligand for quantitation of norepinephrine uptake sites by autoradiography or by homogenate binding
    • Tejani-Butt S.M. [3H]nisoxetine: a radioligand for quantitation of norepinephrine uptake sites by autoradiography or by homogenate binding. J Pharmacol Exp Ther 1992, 260:427-436.
    • (1992) J Pharmacol Exp Ther , vol.260 , pp. 427-436
    • Tejani-Butt, S.M.1
  • 14
    • 21244484658 scopus 로고    scopus 로고
    • Very early treatment with fluoxetine and reboxetine causing long-lasting change of the serotonin but not the noradrenaline transporter in the frontal cortex of rats
    • Bock N., Quentin D.J., Hüther G., Moll G.H., Banaschewski T., Rothenberger A. Very early treatment with fluoxetine and reboxetine causing long-lasting change of the serotonin but not the noradrenaline transporter in the frontal cortex of rats. World J Biol Psychiatry 2005, 6:107-112.
    • (2005) World J Biol Psychiatry , vol.6 , pp. 107-112
    • Bock, N.1    Quentin, D.J.2    Hüther, G.3    Moll, G.H.4    Banaschewski, T.5    Rothenberger, A.6
  • 15
    • 0242340372 scopus 로고    scopus 로고
    • Synthesis and in vivo evaluation of novel radiotracers for the in vivo imaging of the norepinephrine transporter
    • Wilson A.A., Patrick Johnson D., Mozley D., Hussey D., Ginovart N., Nobrega J., et al. Synthesis and in vivo evaluation of novel radiotracers for the in vivo imaging of the norepinephrine transporter. Nucl Med Biol 2003, 30:85-92.
    • (2003) Nucl Med Biol , vol.30 , pp. 85-92
    • Wilson, A.A.1    Patrick Johnson, D.2    Mozley, D.3    Hussey, D.4    Ginovart, N.5    Nobrega, J.6
  • 16
    • 72149110066 scopus 로고    scopus 로고
    • Comparative evaluations of norepinephrine transporter radioligands with reference tissue models in rhesus monkeys: (S, S)-[18F]FMeNER-D2; and (S, S)-[11C]MeNER
    • Takano A., Gulyás B., Varrone A., Halldin C. Comparative evaluations of norepinephrine transporter radioligands with reference tissue models in rhesus monkeys: (S, S)-[18F]FMeNER-D2; and (S, S)-[11C]MeNER. Eur J Nucl Med Mol Imaging 2009, 36:1885-1891.
    • (2009) Eur J Nucl Med Mol Imaging , vol.36 , pp. 1885-1891
    • Takano, A.1    Gulyás, B.2    Varrone, A.3    Halldin, C.4
  • 17
    • 19244366615 scopus 로고    scopus 로고
    • PET evaluation of novel radiofluorinated reboxetine analogs as norepinephrine transporter probes in the monkey brain
    • Schou M., Halldin C., Sóvágó J., Pike V.W., Hall H., Gulyás B., et al. PET evaluation of novel radiofluorinated reboxetine analogs as norepinephrine transporter probes in the monkey brain. Synapse 2004, 53:57-67.
    • (2004) Synapse , vol.53 , pp. 57-67
    • Schou, M.1    Halldin, C.2    Sóvágó, J.3    Pike, V.W.4    Hall, H.5    Gulyás, B.6
  • 18
    • 59449096686 scopus 로고    scopus 로고
    • Investigation of the metabolites of (S, S)-[11C]MeNER in humans, monkeys and rats
    • Schou M., Zoghbi S., Shetty H., Shchukin E., Liow J.-S., Hong J., et al. Investigation of the metabolites of (S, S)-[11C]MeNER in humans, monkeys and rats. Mol Imaging Biol 2009, 11:23-30.
    • (2009) Mol Imaging Biol , vol.11 , pp. 23-30
    • Schou, M.1    Zoghbi, S.2    Shetty, H.3    Shchukin, E.4    Liow, J.-S.5    Hong, J.6
  • 19
    • 55549090301 scopus 로고    scopus 로고
    • Synthesis and activity of novel 1- or 3-(3-amino-1-phenyl propyl)-1,3-dihydro-2H-benzimidazol-2-ones as selective norepinephrine reuptake inhibitors
    • Zhang P., Terefenko E.A., McComas C.C., Mahaney P.E., Vu A., Trybulski E., et al. Synthesis and activity of novel 1- or 3-(3-amino-1-phenyl propyl)-1,3-dihydro-2H-benzimidazol-2-ones as selective norepinephrine reuptake inhibitors. Bioorg Med Chem Lett 2008, 18:6067-6070.
    • (2008) Bioorg Med Chem Lett , vol.18 , pp. 6067-6070
    • Zhang, P.1    Terefenko, E.A.2    McComas, C.C.3    Mahaney, P.E.4    Vu, A.5    Trybulski, E.6
  • 20
    • 0028885828 scopus 로고
    • Syntheses and biological evaluation of N-[4-(2-trans-[([2,6-diamino-4(3H)-oxopyrimidin-5-YL]methyl)thio]cyclobutyl)benzoyl]-L-glutamatic acid a novel 5-thiapyrimidone inhibitor of dihadrofolate-reductase
    • Varney M., Romines W., Boritzki T., Margosiak S., Bartlett C., Howland E. Syntheses and biological evaluation of N-[4-(2-trans-[([2,6-diamino-4(3H)-oxopyrimidin-5-YL]methyl)thio]cyclobutyl)benzoyl]-L-glutamatic acid a novel 5-thiapyrimidone inhibitor of dihadrofolate-reductase. J Heterocycl Chem 1995, 32:1493-1498.
    • (1995) J Heterocycl Chem , vol.32 , pp. 1493-1498
    • Varney, M.1    Romines, W.2    Boritzki, T.3    Margosiak, S.4    Bartlett, C.5    Howland, E.6
  • 21
    • 72049117356 scopus 로고    scopus 로고
    • Efficient and practical asymmetric synthesis of 1-tert-butyl 3-methyl (3R,4R)-4-(2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)piperidine-1,3-dicarboxylate, a useful intermediate for the synthesis of nociceptin antagonists
    • Jona H., Shibata J., Asai M., Goto Y., Arai S., Nakajima S., et al. Efficient and practical asymmetric synthesis of 1-tert-butyl 3-methyl (3R,4R)-4-(2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)piperidine-1,3-dicarboxylate, a useful intermediate for the synthesis of nociceptin antagonists. Tetrahedron: Asymmetry 2009, 20:2439-2446.
    • (2009) Tetrahedron: Asymmetry , vol.20 , pp. 2439-2446
    • Jona, H.1    Shibata, J.2    Asai, M.3    Goto, Y.4    Arai, S.5    Nakajima, S.6
  • 22
    • 0031079411 scopus 로고    scopus 로고
    • Synthesis of [11C]iodomethane by iodination of [11C]methane
    • Larsen P., Ulin J., Dahlstrøm K., Jensen M. Synthesis of [11C]iodomethane by iodination of [11C]methane. Appl Radiat Isot 1997, 48:153-157.
    • (1997) Appl Radiat Isot , vol.48 , pp. 153-157
    • Larsen, P.1    Ulin, J.2    Dahlstrøm, K.3    Jensen, M.4
  • 23
    • 39749117425 scopus 로고    scopus 로고
    • Practical experiences with the synthesis of [11C]CH3I through gas phase iodination reaction using a TRACERlabFXC synthesis module
    • Kniess T., Rode K., Wuest F. Practical experiences with the synthesis of [11C]CH3I through gas phase iodination reaction using a TRACERlabFXC synthesis module. Appl Radiat Isot 2008, 66:482-488.
    • (2008) Appl Radiat Isot , vol.66 , pp. 482-488
    • Kniess, T.1    Rode, K.2    Wuest, F.3
  • 24
    • 0026440649 scopus 로고
    • A simple synthesis of [11C]methyl triflate. International Journal of Radiation Applications and Instrumentation. Part A.
    • Jewett D.M. A simple synthesis of [11C]methyl triflate. International Journal of Radiation Applications and Instrumentation. Part A. Appl Radiat Isot 1992, 43:1383-1385.
    • (1992) Appl Radiat Isot , vol.43 , pp. 1383-1385
    • Jewett, D.M.1
  • 25
    • 84872910449 scopus 로고    scopus 로고
    • Radioactive pharmaceuticals (Radiopharmaceutica, 6.0/0125), European Pharmacopoeia (Europäisches Arzneibuch): Verlag Österreich GmbH; 2008
    • Radioactive pharmaceuticals (Radiopharmaceutica, 6.0/0125), European Pharmacopoeia (Europäisches Arzneibuch): Verlag Österreich GmbH; 2008, p. 995 ff.
  • 26
    • 33746233399 scopus 로고    scopus 로고
    • Synthesis and monoamine transporter affinity of front bridged tricyclic 3β-(4'-halo or 4'-methyl)phenyltropanes bearing methylene or carbomethoxymethylene on the bridge to the 2β-position
    • Zeng F., Jarkas N., Owens M.J., Kilts C.D., Nemeroff C.B., Goodman M.M. Synthesis and monoamine transporter affinity of front bridged tricyclic 3β-(4'-halo or 4'-methyl)phenyltropanes bearing methylene or carbomethoxymethylene on the bridge to the 2β-position. Bioorg Med Chem Lett 2006, 16:4661-4663.
    • (2006) Bioorg Med Chem Lett , vol.16 , pp. 4661-4663
    • Zeng, F.1    Jarkas, N.2    Owens, M.J.3    Kilts, C.D.4    Nemeroff, C.B.5    Goodman, M.M.6
  • 27
    • 0037023334 scopus 로고    scopus 로고
    • Method for measuring the logarithm of the octanol-water partition coefficient by using short octadecyl-poly(vinyl alcohol) high-performance liquid chromatography columns
    • Donovan S.F., Pescatore M.C. Method for measuring the logarithm of the octanol-water partition coefficient by using short octadecyl-poly(vinyl alcohol) high-performance liquid chromatography columns. J Chromatogr A 2002, 952:47-61.
    • (2002) J Chromatogr A , vol.952 , pp. 47-61
    • Donovan, S.F.1    Pescatore, M.C.2
  • 28
    • 84857463177 scopus 로고    scopus 로고
    • In vitro blood-brain barrier models: current and perspective technologies
    • Naik P., Cucullo L. In vitro blood-brain barrier models: current and perspective technologies. J Pharm Sci 2012, 101:1337-1354.
    • (2012) J Pharm Sci , vol.101 , pp. 1337-1354
    • Naik, P.1    Cucullo, L.2
  • 29
    • 79956288365 scopus 로고    scopus 로고
    • Effects of NMDA receptor modulators on a blood-brain barrier in vitro model
    • Neuhaus W., Freidl M., Szkokan P., Berger M., Wirth M., Winkler J., et al. Effects of NMDA receptor modulators on a blood-brain barrier in vitro model. Brain Res 2011, 1394:49-61.
    • (2011) Brain Res , vol.1394 , pp. 49-61
    • Neuhaus, W.1    Freidl, M.2    Szkokan, P.3    Berger, M.4    Wirth, M.5    Winkler, J.6
  • 30
    • 84855316343 scopus 로고    scopus 로고
    • Radiotracer properties determined by high performance liquid chromatography: a potential tool for brain radiotracer discovery
    • Tavares A.A., Lewsey J., Dewar D., Pimlott S.L. Radiotracer properties determined by high performance liquid chromatography: a potential tool for brain radiotracer discovery. Nucl Med Biol 2012, 39:127-135.
    • (2012) Nucl Med Biol , vol.39 , pp. 127-135
    • Tavares, A.A.1    Lewsey, J.2    Dewar, D.3    Pimlott, S.L.4
  • 31
    • 84872943372 scopus 로고    scopus 로고
    • In-vitro stability of [18F]FE@SUPPY and [18F]FE@SUPPY:2 against human liver-microsomes and human plasma
    • Nics L., Vraka C., Hendl M., Haeusler D., Wagner K.-H., Shanab K., et al. In-vitro stability of [18F]FE@SUPPY and [18F]FE@SUPPY:2 against human liver-microsomes and human plasma. Nuklearmed-Nucl Med 2011, 50:A176.
    • (2011) Nuklearmed-Nucl Med , vol.50
    • Nics, L.1    Vraka, C.2    Hendl, M.3    Haeusler, D.4    Wagner, K.-H.5    Shanab, K.6
  • 32
    • 84872974690 scopus 로고    scopus 로고
    • Radioactive metabolites of the 5-HT1A receptor pet radioligand, [carbonyl-11C]way-100635, measured in human plasma samples
    • Någren K., Halldin C., Pike V.W., Allonen T., Hietala J., Swahn C.G., et al. Radioactive metabolites of the 5-HT1A receptor pet radioligand, [carbonyl-11C]way-100635, measured in human plasma samples. J Label Compd Radiopharm 2001, 44:S472-S474.
    • (2001) J Label Compd Radiopharm , vol.44
    • Någren, K.1    Halldin, C.2    Pike, V.W.3    Allonen, T.4    Hietala, J.5    Swahn, C.G.6
  • 33
    • 34248192652 scopus 로고    scopus 로고
    • Metabolite considerations in the in vivo quantification of serotonin transporters using 11C-DASB and PET in humans
    • Parsey R.V., Ojha A., Ogden R.T., Erlandsson K., Kumar D., Landgrebe M., et al. Metabolite considerations in the in vivo quantification of serotonin transporters using 11C-DASB and PET in humans. J Nucl Med 2006, 47:1796-1802.
    • (2006) J Nucl Med , vol.47 , pp. 1796-1802
    • Parsey, R.V.1    Ojha, A.2    Ogden, R.T.3    Erlandsson, K.4    Kumar, D.5    Landgrebe, M.6
  • 34
    • 0035200087 scopus 로고    scopus 로고
    • Positron emission tomography quantification of [11C]-DASB binding to the human serotonin transporter[colon] modeling strategies
    • Ginovart N., Wilson A.A., Meyer J.H., Hussey D., Houle S. Positron emission tomography quantification of [11C]-DASB binding to the human serotonin transporter[colon] modeling strategies. J Cereb Blood Flow Metab 2001, 21:1342-1353.
    • (2001) J Cereb Blood Flow Metab , vol.21 , pp. 1342-1353
    • Ginovart, N.1    Wilson, A.A.2    Meyer, J.H.3    Hussey, D.4    Houle, S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.