Phospholipase c delta 1 is a novel 3p22.3 tumor suppressor involved in cytoskeleton organization, with its epigenetic silencing correlated with high-stage gastric cancer

Oncogene

Volumn 28, Issue 26, 2009, Pages 2466-2475

  Hu, X T ^a   Zhang, F B ^a   Fan, Y C ^b   Shu, X S ^b   Wong, A H Y ^b   Zhou, W ^a   Shi, Q L ^a   Tang, H M ^a   Fu, L ^b   Guan, X Y ^b   Rha, S Y ^c   Tao, Q ^b,d   He, C ^a  

^a ZHEJIANG UNIVERSITY   (China)

^b UNIVERSITY OF HONG KONG   (Hong Kong)

^c Yonsei University College of Medicine   (South Korea)

^d CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

3p22; Gastric cancer; Methylation; PhospholipaseC delta 1; Tumor suppressorgene

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; COFILIN; CYTOSKELETON PROTEIN; MATRILYSIN; PHOSPHOLIPASE C DELTA1;

ADULT; AGED; ARTICLE; CANCER CELL; CANCER CELL CULTURE; CANCER GROWTH; CELL MIGRATION; CELL STRUCTURE; CLONOGENESIS; CONTROLLED STUDY; CPG ISLAND; CYTOSKELETON; DEMETHYLATION; DNA METHYLATION; DOWN REGULATION; EPIGENETICS; FEMALE; GENE EXPRESSION; GENE INACTIVATION; GENE SILENCING; GENOME ANALYSIS; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; PRIMARY TUMOR; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SEQUENCE ANALYSIS; STOMACH CARCINOGENESIS; STOMACH CARCINOMA; STOMACH MUCOSA; TUMOR SUPPRESSOR GENE;

ADULT; AGED; ANIMALS; BASE SEQUENCE; CELL LINE, TUMOR; CELL PROLIFERATION; CHROMOSOMES, HUMAN, PAIR 3; CYTOSKELETON; DNA METHYLATION; DOWN-REGULATION; EPIGENESIS, GENETIC; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE SILENCING; GENES, TUMOR SUPPRESSOR; HUMANS; MALE; MATRIX METALLOPROTEINASE 7; MICE; MIDDLE AGED; MOLECULAR SEQUENCE DATA; PERITONEAL NEOPLASMS; PHOSPHOLIPASE C DELTA; STOMACH NEOPLASMS;

EID: 67650070519     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2009.92     Document Type: Article

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