Trehalose Maintains Bioactivity and Promotes Sustained Release of BMP-2 from Lyophilized CDHA Scaffolds for Enhanced Osteogenesis In Vitro and In Vivo

PLoS ONE

Volumn 8, Issue 1, 2013, Pages

  Zhao, Jun ^a   Wang, Shaoyi ^a   Bao, Jianqiang ^b   Sun, Xiaojuan ^c   Zhang, Xiaochen ^a   Zhang, Xiuli ^a   Ye, Dongxia ^a   Wei, Jie ^d   Liu, Changsheng ^d   Jiang, Xinquan ^a   Shen, Gang ^a   Zhang, Zhiyuan ^a  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b UNIVERSITY OF NEVADA   (United States)

^c NINGXIA MEDICAL UNIVERSITY   (China)

^d East China University of Science and Technology   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BONE MORPHOGENETIC PROTEIN 2; HYDROXYAPATITE; MOLECULAR SCAFFOLD; TREHALASE; TREHALOSE;

ANIMAL EXPERIMENT; ARTICLE; BONE DEVELOPMENT; BONE REGENERATION; CELL DIFFERENTIATION; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; FLUORESCENCE ANALYSIS; FREEZE DRYING; HISTOLOGY; IN VITRO STUDY; IN VIVO STUDY; MALE; MICRO-COMPUTED TOMOGRAPHY; NONHUMAN; PROCESS OPTIMIZATION; PROTEIN FUNCTION; PROTEIN SECRETION; RAT; REAL TIME POLYMERASE CHAIN REACTION; STROMA CELL;

ANIMALS; BONE MORPHOGENETIC PROTEIN 2; CALCIUM; CELL PROLIFERATION; COCULTURE TECHNIQUES; DURAPATITE; FREEZE DRYING; KINETICS; MESENCHYMAL STROMAL CELLS; OSTEOGENESIS; TISSUE SCAFFOLDS; TREHALOSE;

RATTUS;

EID: 84872847320     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0054645     Document Type: Article

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