Effect of trehalose coating on basic fibroblast growth factor release from tailor-made bone implants

Journal of Veterinary Medical Science

Volumn 73, Issue 12, 2011, Pages 1547-1552

  Choi, Sungjin ^a   Lee, Jongil ^b   Igawa, Kazuyo ^c   Suzuki, Shigeki ^a   Mochizuki, Manabu ^a   Nishimura, Ryohei ^a   Chung, Ung il ^b   Sasaki, Nobuo ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b UNIVERSITY OF TOKYO HOSPITAL   (Japan)

^c NEXT21 KK ^*  (Japan)

Author keywords

Artificial bone implant; bFGF; In vitro; Trehalose

Indexed keywords

CALCIUM PHOSPHATE; FIBROBLAST GROWTH FACTOR 2; TREHALOSE;

ANIMAL; ARTICLE; BIODEGRADABLE IMPLANT; BIOMECHANICS; BONE; CELL PROLIFERATION; CHEMISTRY; CYTOLOGY; MOUSE; OSTEOBLAST; PHYSIOLOGY; SCANNING ELECTRON MICROSCOPY; X RAY DIFFRACTION;

ABSORBABLE IMPLANTS; ANIMALS; BIOMECHANICS; BONE AND BONES; CALCIUM PHOSPHATES; CELL PROLIFERATION; FIBROBLAST GROWTH FACTOR 2; MICE; MICROSCOPY, ELECTRON, SCANNING; OSTEOBLASTS; TREHALOSE; X-RAY DIFFRACTION;

EID: 84855449144     PISSN: 09167250     EISSN: 13477439     Source Type: Journal    
DOI: 10.1292/jvms.11-0016     Document Type: Article

References (36)

1. Alam, S., Ueki, K., Marukawa, K., Ohara, T., Hase, T., Takazakura, D. and Nakagawa, K. 2007. Expression of bone morphogenetic protein 2 and fibroblast growth factor 2 during bone regeneration using different implant materials as an onlay bone graft in rabbit mandibles. Oral Surg. Oral Med. Oral Pathol. Oral Radiol. Endod. 103: 16-26.
2. Canalis, E., Economides, A. N. and Gazzerro, E. 2003. Bone morphogenetic proteins, their antagonists, and the skeleton. Endocr. Rev. 24: 218-235.
3. Chen, Q. and Haddad, G. G. 2004. Role of trehalose phosphate synthase and trehalose during hypoxia: from flies to mammals. J. Exp. Biol. 207: 3125-3129.
4. Choi, S. J., Lee, J. I., Igawa, K., Sugimori, O., Suzuki, S., Mochizuki, M., Nishimura, R., Chung, U. I. and Sasaki, N. 2009. Bone regeneration within a tailor-made tricalcium phosphate bone implant with both horizontal and vertical cylindrical holes transplanted into the skull of dogs. J. Artif. Organs 12: 274-277.
5. Dong, X., Wang, Q., Wu, T. and Pan, H. 2007. Understanding adsorption-desorption dynamics of BMP-2 on hydroxyapatite (001) surface. Biophys. J. 93: 750-759.
6. Elbein, A. D., Pan, Y. T., Pastuszak, I. and Carroll, D. 2003. New insights on trehalose: a multifunctional molecule. Glycobiology 13: 17R-27R.
7. Ginebra, M. P., Traykova, T. and Planell, J. A. 2006. Calcium phosphate cements as bone drug delivery systems: a review. J. Control. Release 113: 102-110.
8. Habraken, W. J., Wolke, J. G. and Jansen, J. A. 2007. Ceramic composites as matrices and scaffolds for drug delivery in tissue engineering. Adv. Drug Deliv. Rev. 59: 234-248.
9. Hutmacher, D. W. and Cool, S. 2007. Concepts of scaffoldbased tissue engineering--the rationale to use solid free-form fabrication techniques. J. Cell Mol. Med. 11: 654-669.
10. Igawa, K., Mochizuki, M., Sugimori, O., Shimizu, K., Yamazawa, K., Kawaguchi, H., Nakamura, K., Takato, T., Nishimura, R., Suzuki, S., Anzai, M., Chung, U. I. and Sasaki, N. 2006. Tailor-made tricalcium phosphate bone implant directly fabricated by a three-dimensional ink-jet printer. J. Artif. Organs 9: 234-240.
11. Ishikawa, K. and Asaoka, K. 1995. Estimation of ideal mechanical strength and critical porosity of calcium phosphate cement. J. Biomed. Mater. Res. 29: 1537-1543.
12. Ishikawa, K., Takagi, S., Chow, L. and Ishikawa, Y. 1995. Properties and mechanisms of fast-setting calcium phosphate cements. J. Mater. Sci. Mater. Med. 6: 528-533.
13. Kawaguchi, H. 2005. Stimulation of fracture healing by FGFs. Nippon Rinsho 63: 509-513 (in Japanese).
14. Komaki, H., Tanaka, T., Chazono, M. and Kikuchi, T. 2006. Repair of segmental bone defects in rabbit tibiae using a complex of beta-tricalcium phosphate, type I collagen, and fibroblast growth factor-2. Biomaterials 27: 5118-5126.
15. Le Nihouannen, D., Komarova, S. V., Gbureck, U. and Barralet, J. E. 2008. Bioactivity of bone resorptive factor loaded on osteoconductive matrices: stability post-dehydration. Eur. J. Pharm. Biopharm. 70: 813-818.
16. Liao, Y. H., Brown, M. B., Nazir, T., Quader, A. and Martin, G. P. 2002. Effects of sucrose and trehalose on the preservation of the native structure of spray-dried lysozyme. Pharm. Res. 19: 1847-1853.
17. Liu, Y., Hunziker, E. B., Randall, N. X., de Groot, K. and Layrolle, P. 2003. Proteins incorporated into biomimetically prepared calcium phosphate coatings modulate their mechanical strength and dissolution rate. Biomaterials 24: 65-70.
18. Martin, I., Muraglia, A., Campanile, G., Cancedda, R. and Quarto, R. 1997. Fibroblast growth factor-2 supports ex vivo expansion and maintenance of osteogenic precursors from human bone marrow. Endocrinology 138: 4456-4462.
19. Matsumoto, T., Okazaki, M., Inoue, M., Yamaguchi, S., Kusunose, T., Toyonaga, T., Hamada, Y. and Takahashi, J. 2004. Hydroxyapatite particles as a controlled release carrier of protein. Biomaterials 25: 3807-3812.
20. Midy, V., Rey, C., Bres, E. and Dard, M. 1998. Basic fibroblast growth factor adsorption and release properties of calcium phosphate. J. Biomed. Mater. Res. 41: 405-411.
21. Milovancev, M., Muir, P., Manley, P. A., Seeherman, H. J. and Schaefer, S. 2007. Clinical application of recombinant human bone morphogenetic protein-2 in 4 dogs. Vet. Surg. 36: 132-140.
22. Minutoli, L., Altavilla, D., Bitto, A., Polito, F., Bellocco, E., Lagana, G., Fiumara, T., Magazu, S., Migliardo, F., Venuti, F. S. and Squadrito, F. 2008. Trehalose: a biophysics approach to modulate the inflammatory response during endotoxic shock. Eur. J. Pharmacol. 589: 272-280.
23. Miyamoto, Y., Ishikawa, K., Fukao, H., Sawada, M., Nagayama, M., Kon, M. and Asaoka, K. 1995. In vivo setting behaviour of fast-setting calcium phosphate cement. Biomaterials 16: 855-860.
24. Niedhart, C., Maus, U., Miltner, O., Graber, H. G., Niethard, F. U. and Siebert, C. H. 2004. The effect of basic fibroblast growth factor on bone regeneration when released from a novel in situ setting tricalcium phosphate cement. J. Biomed. Mater. Res. A 69: 680-685.
25. Onuma, K., Kanzaki, N. and Kobayashi, N. 2004. Association of calcium phosphate and fibroblast growth factor-2: a dynamic light scattering study. Macromol. Biosci. 4: 39-46.
26. Richards, A. B., Krakowka, S., Dexter, L. B., Schmid, H., Wolterbeek, A. P., Waalkens-Berendsen, D. H., Shigoyuki, A. and Kurimoto, M. 2002. Trehalose: a review of properties, history of use and human tolerance, and results of multiple safety studies. Food Chem. Toxicol. 40: 871-898.
27. Seshima, H., Yoshinari, M., Takemoto, S., Hattori, M., Kawada, E., Inoue, T. and Oda, Y. 2006. Control of bisphosphonate release using hydroxyapatite granules. J. Biomed. Mater. Res. B Appl. Biomater. 78: 215-221.
28. Suda, T. 2007. Mechanism of calcification. pp. 145-174. In: Bone Biology, 1st ed., Ishiyaku publishers, Tokyo.
29. Sum, A. K., Faller, R. and de Pablo, J. J. 2003. Molecular simulation study of phospholipid bilayers and insights of the interactions with disaccharides. Biophys. J. 85: 2830-2844.
30. Talal, A., Waheed, N., Al-Masri, M., McKay, I. J., Tanner, K. E. and Hughes, F. J. 2009. Absorption and release of protein from hydroxyapatite-polylactic acid (HA-PLA) membranes. J. Dent. 37: 820-826.
31. Tazaki, J., Murata, M., Akazawa, T., Yamamoto, M., Ito, K., Arisue, M., Shibata, T. and Tabata, Y. 2009. BMP-2 release and dose-response studies in hydroxyapatite and beta-tricalcium phosphate. Biomed. Mater. Eng. 19: 141-146.
32. Wassell, D. T., Hall, R. C. and Embery, G. 1995. Adsorption of bovine serum albumin onto hydroxyapatite. Biomaterials 16: 697-702.
33. Willart, J. F., Hedoux, A., Guinet, Y., Danede, F., Paccou, L., Capet, F. and Descamps, M. 2006. Metastability release of the form alpha of trehalose by isothermal solid state vitrification. J. Phys. Chem. B 110: 11040-11043.
34. Wronski, T. J. 2001. Skeletal effects of systemic treatment with basic fibroblast growth factor. J. Musculoskelet. Neuronal. Interact. 2: 9-14.
35. Yamaguchi, A., Komori, T. and Suda, T. 2000. Regulation of osteoblast differentiation mediated by bone morphogenetic proteins, hedgehogs, and Cbfa1. Endocr. Rev. 21: 393-411.
36. Ziegler, J., Mayr-Wohlfart, U., Kessler, S., Breitig, D. and Gunther, K. P. 2002. Adsorption and release properties of growth factors from biodegradable implants. J. Biomed. Mater. Res. 59: 422-428.