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Volumn 29, Issue 29, 2008, Pages 3983-3992

The effect of platelet-rich plasma on healing in critical-size long-bone defects

Author keywords

Bone healing; Bone regeneration; Bone tissue engineering; Calcium phosphate; Platelet; Stem cell

Indexed keywords

BONE DEFECTS; BONE FORMATION; BONE HEALING; CALCIUM DEFICIENT HYDROXYAPATITE (CDHA); COMPUTER TOMOGRAPHY (CT); MESENCHYMAL STEM CELLS (MSCS); PLATELET-RICH-PLASMA (PRP); RABBIT MODELS;

EID: 48349088923     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2008.06.014     Document Type: Article
Times cited : (195)

References (51)
  • 2
    • 0026218510 scopus 로고
    • Bone graft and bone graft substitutes: review of current technology and applications
    • Damien C., and Parsons R. Bone graft and bone graft substitutes: review of current technology and applications. J Appl Biomat 2 (1991) 187-208
    • (1991) J Appl Biomat , vol.2 , pp. 187-208
    • Damien, C.1    Parsons, R.2
  • 3
    • 2942659769 scopus 로고    scopus 로고
    • Effects of platelet-rich plasma on bone healing in combination with autogenous bone and bone substitutes in critical-size defects
    • Wiltfang J., Kloss F.R., Kessler P., Nkenke E., Schultze-Mosgau S., Zimmermann R., et al. Effects of platelet-rich plasma on bone healing in combination with autogenous bone and bone substitutes in critical-size defects. Clin Oral Implants Res 15 2 (2004) 187-193
    • (2004) Clin Oral Implants Res , vol.15 , Issue.2 , pp. 187-193
    • Wiltfang, J.1    Kloss, F.R.2    Kessler, P.3    Nkenke, E.4    Schultze-Mosgau, S.5    Zimmermann, R.6
  • 5
    • 0037411447 scopus 로고    scopus 로고
    • Comparison of human bone marrow stromal cells seeded on calcium-deficient hydroxyapatite, ß-tricalcium phosphate and demineralized bone matrix
    • Kasten P., Luginbühl R., van Griensven M., Barkhausen T., Krettek C., Bohner M., et al. Comparison of human bone marrow stromal cells seeded on calcium-deficient hydroxyapatite, ß-tricalcium phosphate and demineralized bone matrix. Biomaterials 24 15 (2003) 2593-2603
    • (2003) Biomaterials , vol.24 , Issue.15 , pp. 2593-2603
    • Kasten, P.1    Luginbühl, R.2    van Griensven, M.3    Barkhausen, T.4    Krettek, C.5    Bohner, M.6
  • 6
    • 4544256924 scopus 로고    scopus 로고
    • [Induction of bone tissue on different biomaterials: an in vitro and a pilot in vivo study in the SCID mouse]
    • Kasten P., Luginbuhl R., Vogel J., Niemeyer P., Weiss S., van Griensven M., et al. [Induction of bone tissue on different biomaterials: an in vitro and a pilot in vivo study in the SCID mouse]. Z Orthop Ihre Grenzgeb 142 4 (2004) 467-475
    • (2004) Z Orthop Ihre Grenzgeb , vol.142 , Issue.4 , pp. 467-475
    • Kasten, P.1    Luginbuhl, R.2    Vogel, J.3    Niemeyer, P.4    Weiss, S.5    van Griensven, M.6
  • 7
    • 20444427591 scopus 로고    scopus 로고
    • Ectopic bone formation associated with mesenchymal stem cells in a resorbable Calcium deficient hydroxyapatite carrier
    • Kasten P., Vogel J., Luginbuhl R., Niemeyer P., Tonak M., Lorenz H., et al. Ectopic bone formation associated with mesenchymal stem cells in a resorbable Calcium deficient hydroxyapatite carrier. Biomaterials 26/29 (2005) 5879-5889
    • (2005) Biomaterials , vol.26-29 , pp. 5879-5889
    • Kasten, P.1    Vogel, J.2    Luginbuhl, R.3    Niemeyer, P.4    Tonak, M.5    Lorenz, H.6
  • 8
    • 0030889354 scopus 로고    scopus 로고
    • Marrow stromal cells as stem cells for nonhematopoetic tissues
    • Prockop D.J. Marrow stromal cells as stem cells for nonhematopoetic tissues. Science 276 (1997) 71-74
    • (1997) Science , vol.276 , pp. 71-74
    • Prockop, D.J.1
  • 10
    • 0031868140 scopus 로고    scopus 로고
    • The effect of implants loaded with autologous mesenchymal stem cells on the healing of canine segmental bone defects
    • Bruder S.P., Kraus K.H., Goldberg V.M., and Kadiyala S. The effect of implants loaded with autologous mesenchymal stem cells on the healing of canine segmental bone defects. J Bone Joint Surg Am 80 7 (1998) 985-996
    • (1998) J Bone Joint Surg Am , vol.80 , Issue.7 , pp. 985-996
    • Bruder, S.P.1    Kraus, K.H.2    Goldberg, V.M.3    Kadiyala, S.4
  • 11
    • 0032822929 scopus 로고    scopus 로고
    • Osteoinductive growth factors in preclinical fracture and long bone defects models
    • Bostrom M.P., Saleh K.J., and Einhorn T.A. Osteoinductive growth factors in preclinical fracture and long bone defects models. Orthop Clin North Am 30 (1999) 647-658
    • (1999) Orthop Clin North Am , vol.30 , pp. 647-658
    • Bostrom, M.P.1    Saleh, K.J.2    Einhorn, T.A.3
  • 12
    • 0026043850 scopus 로고
    • Cytoskeleton-dependent release of human platelet epidermal growth factor
    • Kiuru J., Viinikka L., Myllyla G., Personen K., and Perheentupa J. Cytoskeleton-dependent release of human platelet epidermal growth factor. Life Sci 49 (1991) 1997-2003
    • (1991) Life Sci , vol.49 , pp. 1997-2003
    • Kiuru, J.1    Viinikka, L.2    Myllyla, G.3    Personen, K.4    Perheentupa, J.5
  • 13
    • 0038600611 scopus 로고    scopus 로고
    • Platelet-rich plasma-derived fibrin clot formation stimulates collagen synthesis in periodontal ligament and osteoblastic cells in vitro
    • Kawase T., Okuda K., Wolff L.F., and Yoshie H. Platelet-rich plasma-derived fibrin clot formation stimulates collagen synthesis in periodontal ligament and osteoblastic cells in vitro. J Periodontol 74 6 (2003) 858-864
    • (2003) J Periodontol , vol.74 , Issue.6 , pp. 858-864
    • Kawase, T.1    Okuda, K.2    Wolff, L.F.3    Yoshie, H.4
  • 15
    • 0346399659 scopus 로고    scopus 로고
    • Effect of platelet-rich plasma on bone regeneration in autogenous bone graft
    • Choi B.H., Im C.J., Huh J.Y., Suh J.J., and Lee S.H. Effect of platelet-rich plasma on bone regeneration in autogenous bone graft. Int J Oral Maxillofac Surg 33 1 (2004) 56-59
    • (2004) Int J Oral Maxillofac Surg , vol.33 , Issue.1 , pp. 56-59
    • Choi, B.H.1    Im, C.J.2    Huh, J.Y.3    Suh, J.J.4    Lee, S.H.5
  • 16
    • 33644977736 scopus 로고    scopus 로고
    • The effects of local platelet rich plasma delivery on diabetic fracture healing
    • Gandhi A., Dumas C., O'Connor J.P., Parsons J.R., and Lin S.S. The effects of local platelet rich plasma delivery on diabetic fracture healing. Bone 38 4 (2006) 540-546
    • (2006) Bone , vol.38 , Issue.4 , pp. 540-546
    • Gandhi, A.1    Dumas, C.2    O'Connor, J.P.3    Parsons, J.R.4    Lin, S.S.5
  • 17
    • 4043099057 scopus 로고    scopus 로고
    • Anterior lumbar interbody fusion with carbon fiber cage loaded with bioceramics and platelet-rich plasma. An experimental study on pigs
    • Li H., Zou X., Xue Q., Egund N., Lind M., and Bunger C. Anterior lumbar interbody fusion with carbon fiber cage loaded with bioceramics and platelet-rich plasma. An experimental study on pigs. Eur Spine J 13 4 (2004) 354-358
    • (2004) Eur Spine J , vol.13 , Issue.4 , pp. 354-358
    • Li, H.1    Zou, X.2    Xue, Q.3    Egund, N.4    Lind, M.5    Bunger, C.6
  • 18
    • 0942268151 scopus 로고    scopus 로고
    • Bone formation in the presence of platelet-rich plasma vs. bone morphogenetic protein-7
    • Roldan J.C., Jepsen S., Miller J., Freitag S., Rueger D.C., Acil Y., et al. Bone formation in the presence of platelet-rich plasma vs. bone morphogenetic protein-7. Bone 34 1 (2004) 80-90
    • (2004) Bone , vol.34 , Issue.1 , pp. 80-90
    • Roldan, J.C.1    Jepsen, S.2    Miller, J.3    Freitag, S.4    Rueger, D.C.5    Acil, Y.6
  • 19
    • 3042771201 scopus 로고    scopus 로고
    • Autogenous injectable bone for regeneration with mesenchymal stem cells and platelet-rich plasma: tissue-engineered bone regeneration
    • Yamada Y., Ueda M., Naiki T., Takahashi M., Hata K., and Nagasaka T. Autogenous injectable bone for regeneration with mesenchymal stem cells and platelet-rich plasma: tissue-engineered bone regeneration. Tissue Eng 10 5-6 (2004) 955-964
    • (2004) Tissue Eng , vol.10 , Issue.5-6 , pp. 955-964
    • Yamada, Y.1    Ueda, M.2    Naiki, T.3    Takahashi, M.4    Hata, K.5    Nagasaka, T.6
  • 20
    • 0034447773 scopus 로고    scopus 로고
    • Calcium orthophosphates in medicine: from ceramics to calcium phosphate cements
    • Bohner M. Calcium orthophosphates in medicine: from ceramics to calcium phosphate cements. Injury 31 Suppl 4 (2000) 37-47
    • (2000) Injury , vol.31 , Issue.SUPPL. 4 , pp. 37-47
    • Bohner, M.1
  • 21
    • 0036166394 scopus 로고    scopus 로고
    • Properties of osteoconductive biomaterials: calcium phosphates
    • LeGeros R.Z. Properties of osteoconductive biomaterials: calcium phosphates. Clin Orthop 395 Feb (2002) 81-98
    • (2002) Clin Orthop , vol.395 , Issue.Feb , pp. 81-98
    • LeGeros, R.Z.1
  • 22
    • 0035525779 scopus 로고    scopus 로고
    • Purification and ex vivo expansion of postnatal human marrow mesodermal progenitor cells
    • Reyes M., Lund T., Lenvik T., Aguiar D., Koodie L., and Verfaillie C.M. Purification and ex vivo expansion of postnatal human marrow mesodermal progenitor cells. Blood 98 9 (2001) 2615-2625
    • (2001) Blood , vol.98 , Issue.9 , pp. 2615-2625
    • Reyes, M.1    Lund, T.2    Lenvik, T.3    Aguiar, D.4    Koodie, L.5    Verfaillie, C.M.6
  • 23
    • 33750515870 scopus 로고    scopus 로고
    • Platelet-rich plasma improves expansion of human mesenchymal stem cells and retains differentiation capacity and in vivo bone formation in calcium phosphate ceramics
    • Vogel J.P., Szalay K., Geiger F., Kramer M., Richter W., and Kasten P. Platelet-rich plasma improves expansion of human mesenchymal stem cells and retains differentiation capacity and in vivo bone formation in calcium phosphate ceramics. Platelets 17 7 (2006) 462-469
    • (2006) Platelets , vol.17 , Issue.7 , pp. 462-469
    • Vogel, J.P.1    Szalay, K.2    Geiger, F.3    Kramer, M.4    Richter, W.5    Kasten, P.6
  • 24
    • 0020264072 scopus 로고
    • Osteogenetic properties of reimplanted decalcified and undecalcified autologous bone in the rabbit radius
    • Wittbjer J., Palmer B., and Thorngren K.G. Osteogenetic properties of reimplanted decalcified and undecalcified autologous bone in the rabbit radius. Scand J Plast Reconstr Surg 16 3 (1982) 239-244
    • (1982) Scand J Plast Reconstr Surg , vol.16 , Issue.3 , pp. 239-244
    • Wittbjer, J.1    Palmer, B.2    Thorngren, K.G.3
  • 25
    • 27444447463 scopus 로고    scopus 로고
    • Vascular endothelial growth factor gene-activated matrix (VEGF165-GAM) enhances osteogenesis and angiogenesis in large segmental bone defects
    • Geiger F., Bertram H., Berger I., Lorenz H., Wall O., Eckhardt C., et al. Vascular endothelial growth factor gene-activated matrix (VEGF165-GAM) enhances osteogenesis and angiogenesis in large segmental bone defects. J Bone Miner Res 20 11 (2005) 2028-2035
    • (2005) J Bone Miner Res , vol.20 , Issue.11 , pp. 2028-2035
    • Geiger, F.1    Bertram, H.2    Berger, I.3    Lorenz, H.4    Wall, O.5    Eckhardt, C.6
  • 26
    • 0032917041 scopus 로고    scopus 로고
    • Improved bone biomechanical properties in rats after oral xylitol administration
    • Mattila P., Knuuttila M., Kovanen V., and Svanberg M. Improved bone biomechanical properties in rats after oral xylitol administration. Calcif Tissue Int 64 4 (1999) 340-344
    • (1999) Calcif Tissue Int , vol.64 , Issue.4 , pp. 340-344
    • Mattila, P.1    Knuuttila, M.2    Kovanen, V.3    Svanberg, M.4
  • 29
    • 10744221865 scopus 로고    scopus 로고
    • Comparative study of beta-tricalcium phosphate mixed with platelet-rich plasma versus beta-tricalcium phosphate, a bone substitute material in dentistry
    • Kovacs K., Velich N., Huszar T., Szabo G., Semjen G., Reiczigel J., et al. Comparative study of beta-tricalcium phosphate mixed with platelet-rich plasma versus beta-tricalcium phosphate, a bone substitute material in dentistry. Acta Vet Hung 51 4 (2003) 475-484
    • (2003) Acta Vet Hung , vol.51 , Issue.4 , pp. 475-484
    • Kovacs, K.1    Velich, N.2    Huszar, T.3    Szabo, G.4    Semjen, G.5    Reiczigel, J.6
  • 30
    • 0142024937 scopus 로고    scopus 로고
    • Enhanced bone-to-implant contact by platelet-released growth factors in mandibular cortical bone: a histomorphometric study in minipigs
    • Fuerst G., Gruber R., Tangl S., Sanroman F., and Watzek G. Enhanced bone-to-implant contact by platelet-released growth factors in mandibular cortical bone: a histomorphometric study in minipigs. Int J Oral Maxillofac Implants 18 5 (2003) 685-690
    • (2003) Int J Oral Maxillofac Implants , vol.18 , Issue.5 , pp. 685-690
    • Fuerst, G.1    Gruber, R.2    Tangl, S.3    Sanroman, F.4    Watzek, G.5
  • 32
    • 1442290154 scopus 로고    scopus 로고
    • Platelet-released supernatants increase migration and proliferation, and decrease osteogenic differentiation of bone marrow-derived mesenchymal progenitor cells under in vitro conditions
    • Gruber R., Karreth F., Kandler B., Fuerst G., Rot A., Fischer M.B., et al. Platelet-released supernatants increase migration and proliferation, and decrease osteogenic differentiation of bone marrow-derived mesenchymal progenitor cells under in vitro conditions. Platelets 15 1 (2004) 29-35
    • (2004) Platelets , vol.15 , Issue.1 , pp. 29-35
    • Gruber, R.1    Karreth, F.2    Kandler, B.3    Fuerst, G.4    Rot, A.5    Fischer, M.B.6
  • 33
    • 48349114159 scopus 로고    scopus 로고
    • Use of platelet rich plasma (PRP) in the reconstruction of mandibular bony defects: clinical and radiographic follow-up
    • [Epub ahead of print]
    • Al Sukhun J., Helenius M., Lindqvist C., and Thoren H. Use of platelet rich plasma (PRP) in the reconstruction of mandibular bony defects: clinical and radiographic follow-up. Br J Oral Maxillofac Surg (2007 Jan 6) [Epub ahead of print]
    • (2007) Br J Oral Maxillofac Surg
    • Al Sukhun, J.1    Helenius, M.2    Lindqvist, C.3    Thoren, H.4
  • 34
    • 33750252046 scopus 로고    scopus 로고
    • Topical application of platelets for improved wound healing
    • Dugrillon A., and Klüter H. Topical application of platelets for improved wound healing. Blood Ther Med 3 1 (2002) 21-26
    • (2002) Blood Ther Med , vol.3 , Issue.1 , pp. 21-26
    • Dugrillon, A.1    Klüter, H.2
  • 35
    • 0345768566 scopus 로고    scopus 로고
    • Mandibular reconstruction: a histological and histomorphometric study on the use of autogenous scaffolds, particulate cortico-cancellous bone grafts and platelet rich plasma in goats
    • Fennis J.P., Stoelinga P.J., and Jansen J.A. Mandibular reconstruction: a histological and histomorphometric study on the use of autogenous scaffolds, particulate cortico-cancellous bone grafts and platelet rich plasma in goats. Int J Oral Maxillofac Surg 33 1 (2004) 48-55
    • (2004) Int J Oral Maxillofac Surg , vol.33 , Issue.1 , pp. 48-55
    • Fennis, J.P.1    Stoelinga, P.J.2    Jansen, J.A.3
  • 37
    • 1342343195 scopus 로고    scopus 로고
    • Evaluation of platelet-rich plasma in combination with anorganic bovine bone in the rabbit cranium: a pilot study
    • Aghaloo T.L., Moy P.K., and Freymiller E.G. Evaluation of platelet-rich plasma in combination with anorganic bovine bone in the rabbit cranium: a pilot study. Int J Oral Maxillofac Implants 19 1 (2004) 59-65
    • (2004) Int J Oral Maxillofac Implants , vol.19 , Issue.1 , pp. 59-65
    • Aghaloo, T.L.1    Moy, P.K.2    Freymiller, E.G.3
  • 38
    • 34347205208 scopus 로고    scopus 로고
    • The effect of platelet-rich plasma on early and late bone healing: an experimental study in goats
    • Mooren R.E., Merkx M.A., Bronkhorst E.M., Jansen J.A., and Stoelinga P.J. The effect of platelet-rich plasma on early and late bone healing: an experimental study in goats. Int J Oral Maxillofac Surg 36 7 (2007) 626-631
    • (2007) Int J Oral Maxillofac Surg , vol.36 , Issue.7 , pp. 626-631
    • Mooren, R.E.1    Merkx, M.A.2    Bronkhorst, E.M.3    Jansen, J.A.4    Stoelinga, P.J.5
  • 39
    • 33947521671 scopus 로고    scopus 로고
    • The effect of platelet-rich plasma on bone healing around implants placed in bone defects treated with Bio-Oss: a pilot study in the dog tibia
    • You T.M., Choi B.H., Li J., Jung J.H., Lee H.J., Lee S.H., et al. The effect of platelet-rich plasma on bone healing around implants placed in bone defects treated with Bio-Oss: a pilot study in the dog tibia. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 103 4 (2007) e8-e12
    • (2007) Oral Surg Oral Med Oral Pathol Oral Radiol Endod , vol.103 , Issue.4
    • You, T.M.1    Choi, B.H.2    Li, J.3    Jung, J.H.4    Lee, H.J.5    Lee, S.H.6
  • 40
    • 34548697508 scopus 로고    scopus 로고
    • Platelet-rich plasma may not provide any additional effect when associated with guided bone regeneration around dental implants in dogs
    • Vasconcelos Gurgel B.C., Goncalves P.F., Pimentel S.P., Ambrosano G.M., Nociti Junior F.H., Sallum E.A., et al. Platelet-rich plasma may not provide any additional effect when associated with guided bone regeneration around dental implants in dogs. Clin Oral Implants Res 18 5 (2007) 649-654
    • (2007) Clin Oral Implants Res , vol.18 , Issue.5 , pp. 649-654
    • Vasconcelos Gurgel, B.C.1    Goncalves, P.F.2    Pimentel, S.P.3    Ambrosano, G.M.4    Nociti Junior, F.H.5    Sallum, E.A.6
  • 41
    • 33847668250 scopus 로고    scopus 로고
    • Early effect of platelet-rich plasma on bone healing in combination with an osteoconductive material in rat cranial defects
    • Plachokova A.S., van den Dolder J., Stoelinga P.J., and Jansen J.A. Early effect of platelet-rich plasma on bone healing in combination with an osteoconductive material in rat cranial defects. Clin Oral Implants Res 18 2 (2007) 244-251
    • (2007) Clin Oral Implants Res , vol.18 , Issue.2 , pp. 244-251
    • Plachokova, A.S.1    van den Dolder, J.2    Stoelinga, P.J.3    Jansen, J.A.4
  • 42
    • 36248964731 scopus 로고    scopus 로고
    • Early bone formation in human bone grafts treated with platelet-rich plasma: preliminary histomorphometric results
    • Thor A., Franke-Stenport V., Johansson C.B., and Rasmusson L. Early bone formation in human bone grafts treated with platelet-rich plasma: preliminary histomorphometric results. Int J Oral Maxillofac Surg 36 12 (2007) 1164-1171
    • (2007) Int J Oral Maxillofac Surg , vol.36 , Issue.12 , pp. 1164-1171
    • Thor, A.1    Franke-Stenport, V.2    Johansson, C.B.3    Rasmusson, L.4
  • 43
    • 33750273222 scopus 로고    scopus 로고
    • Influence of platelet-rich plasma on osteogenic differentiation of mesenchymal stem cells and ectopic bone formation in calcium phosphate ceramics
    • Kasten P., Vogel J., Luginbuhl R., Niemeyer P., Weiss S., Schneider S., et al. Influence of platelet-rich plasma on osteogenic differentiation of mesenchymal stem cells and ectopic bone formation in calcium phosphate ceramics. Cells Tissues Organs 183 2 (2006) 68-79
    • (2006) Cells Tissues Organs , vol.183 , Issue.2 , pp. 68-79
    • Kasten, P.1    Vogel, J.2    Luginbuhl, R.3    Niemeyer, P.4    Weiss, S.5    Schneider, S.6
  • 44
    • 0041380844 scopus 로고    scopus 로고
    • Comparison of platelet, leukocyte, and growth factor levels in point-of-care platelet-enriched plasma, prepared using a modified Curasan kit, with preparations received from a local blood bank
    • Weibrich G., Kleis W.K., Hafner G., Hitzler W.E., and Wagner W. Comparison of platelet, leukocyte, and growth factor levels in point-of-care platelet-enriched plasma, prepared using a modified Curasan kit, with preparations received from a local blood bank. Clin Oral Implants Res 14 3 (2003) 357-362
    • (2003) Clin Oral Implants Res , vol.14 , Issue.3 , pp. 357-362
    • Weibrich, G.1    Kleis, W.K.2    Hafner, G.3    Hitzler, W.E.4    Wagner, W.5
  • 45
    • 33751570736 scopus 로고    scopus 로고
    • Platelet-rich plasma: quantification of growth factor levels and the effect on growth and differentiation of rat bone marrow cells
    • van den Dolder J., Mooren R., Vloon A.P., Stoelinga P.J., and Jansen J.A. Platelet-rich plasma: quantification of growth factor levels and the effect on growth and differentiation of rat bone marrow cells. Tissue Eng 12 11 (2006) 3067-3073
    • (2006) Tissue Eng , vol.12 , Issue.11 , pp. 3067-3073
    • van den Dolder, J.1    Mooren, R.2    Vloon, A.P.3    Stoelinga, P.J.4    Jansen, J.A.5
  • 46
    • 0036561039 scopus 로고    scopus 로고
    • [Growth stimulation of human osteoblast-like cells by thrombocyte concentrates in vitro]
    • Weibrich G., Gnoth S.H., Otto M., Reichert T.E., and Wagner W. [Growth stimulation of human osteoblast-like cells by thrombocyte concentrates in vitro]. Mund Kiefer Gesichtschir 6 3 (2002) 168-174
    • (2002) Mund Kiefer Gesichtschir , vol.6 , Issue.3 , pp. 168-174
    • Weibrich, G.1    Gnoth, S.H.2    Otto, M.3    Reichert, T.E.4    Wagner, W.5
  • 47
    • 0036599845 scopus 로고    scopus 로고
    • The role of growth factors in the repair of bone
    • Biology and clinical applications
    • Lieberman J.R., Daluiski A., and Einhorn T.A. The role of growth factors in the repair of bone. Biology and clinical applications. J Bone Joint Surg Am 84-A 6 (2002) 1032-1044
    • (2002) J Bone Joint Surg Am , vol.84 -A , Issue.6 , pp. 1032-1044
    • Lieberman, J.R.1    Daluiski, A.2    Einhorn, T.A.3
  • 49
    • 34548543843 scopus 로고    scopus 로고
    • VEGF producing bone marrow stromal cells (BMSC) enhance vascularization and resorption of a natural coral bone substitute
    • Geiger F., Lorenz H., Xu W., Szalay K., Kasten P., Claes L., et al. VEGF producing bone marrow stromal cells (BMSC) enhance vascularization and resorption of a natural coral bone substitute. Bone 41 4 (2007) 516-522
    • (2007) Bone , vol.41 , Issue.4 , pp. 516-522
    • Geiger, F.1    Lorenz, H.2    Xu, W.3    Szalay, K.4    Kasten, P.5    Claes, L.6
  • 50
    • 40349116487 scopus 로고    scopus 로고
    • Healing modulation induced by freeze-dried platelet-rich plasma and micronized allogenic dermis in a diabetic wound model
    • Pietramaggiori G., Scherer S.S., Mathews J.C., Alperovich M., Yang H.J., Neuwalder J., et al. Healing modulation induced by freeze-dried platelet-rich plasma and micronized allogenic dermis in a diabetic wound model. Wound Repair Regen 16 2 (2008) 218-225
    • (2008) Wound Repair Regen , vol.16 , Issue.2 , pp. 218-225
    • Pietramaggiori, G.1    Scherer, S.S.2    Mathews, J.C.3    Alperovich, M.4    Yang, H.J.5    Neuwalder, J.6


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