-
1
-
-
3543102542
-
Inflammation and necrosis promote tumour growth
-
Vakkila J and Lotze MT: Inflammation and necrosis promote tumour growth. Nat Rev Immunol 4: 641-648, 2004. (Pubitemid 39025049)
-
(2004)
Nature Reviews Immunology
, vol.4
, Issue.8
, pp. 641-648
-
-
Vakkila, J.1
Lotze, M.T.2
-
2
-
-
33846244269
-
Role of autophagy in cancer: Management of metabolic stress
-
Jin S and White E: Role of autophagy in cancer: management of metabolic stress. Autophagy 3: 28-31, 2007. (Pubitemid 46100707)
-
(2007)
Autophagy
, vol.3
, Issue.1
, pp. 28-31
-
-
Jin, S.1
White, E.2
-
3
-
-
17144376810
-
High-mobility group box 1 protein (HMGB1): Nuclear weapon in the immune arsenal
-
DOI 10.1038/nri1594
-
Lotze MT and Tracey KJ: High-mobility group box 1 protein (HMGB1): nuclear weapon in the immune arsenal. Nat Rev Immunol 5: 331-342, 2005. (Pubitemid 40516158)
-
(2005)
Nature Reviews Immunology
, vol.5
, Issue.4
, pp. 331-342
-
-
Lotze, M.T.1
Tracey, K.J.2
-
4
-
-
17144400438
-
Angiogenetic signaling through hypoxia HMGB1: An angiogenetic switch molecule
-
Schlueter C, Weber H, Meyer B, Rogalla P, Roser K, Hauke S and Bullerdiek J: Angiogenetic signaling through hypoxia: HMGB1: an angiogenetic switch molecule. Am J Pathol 166: 1259-1263, 2005. (Pubitemid 40524448)
-
(2005)
American Journal of Pathology
, vol.166
, Issue.4
, pp. 1259-1263
-
-
Schlueter, C.1
Weber, H.2
Meyer, B.3
Rogalla, P.4
Roser, K.5
Hauke, S.6
Bullerdiek, J.7
-
5
-
-
8144228566
-
Why do cancers have high aerobic glycolysis?
-
DOI 10.1038/nrc1478
-
Gatenby RA and Gillies RJ: Why do cancers have high aerobic glycolysis? Nat Rev Cancer 4: 891-899, 2004. (Pubitemid 39472955)
-
(2004)
Nature Reviews Cancer
, vol.4
, Issue.11
, pp. 891-899
-
-
Gatenby, R.A.1
Gillies, R.J.2
-
6
-
-
0036270508
-
Egr1 transcription factor: Multiple roles in prostate tumor cell growth and survival
-
DOI 10.1159/000059711
-
Adamson ED and Mercola D: Egr1 transcription factor: multiple roles in prostate tumor cell growth and survival. Tumour Biol 23: 93-102, 2002. (Pubitemid 34639111)
-
(2002)
Tumor Biology
, vol.23
, Issue.2
, pp. 93-102
-
-
Adamson, E.D.1
Mercola, D.2
-
7
-
-
0036888651
-
Regulation of life and death by the zinc finger transcription factor Egr-1
-
DOI 10.1002/jcp.10178
-
Thiel G and Cibelli G: Regulation of life and death by the zinc finger transcription factor Egr-1. J Cell Physiol 193: 287-292, 2002. (Pubitemid 35265949)
-
(2002)
Journal of Cellular Physiology
, vol.193
, Issue.3
, pp. 287-292
-
-
Thiel, G.1
Cibelli, G.2
-
8
-
-
79955707098
-
Egr-1 transactivates Bim gene expression to promote neuronal apoptosis
-
Xie B, Wang C, Zheng Z, Song B, Ma C, Thiel G and Li M: Egr-1 transactivates Bim gene expression to promote neuronal apoptosis. J Neurosci 31: 5032-5044, 2011.
-
(2011)
J Neurosci
, vol.31
, pp. 5032-5044
-
-
Xie, B.1
Wang, C.2
Zheng, Z.3
Song, B.4
Ma, C.5
Thiel, G.6
Li, M.7
-
9
-
-
77958015556
-
Adenovirus 5 E1A enhances histone deacetylase inhibitors-induced apoptosis through Egr-1-mediated Bim upregulation
-
Yamaguchi H, Chen CT, Chou CK, Pal A, Bornmann W, Hortobagyi GN and Hung MC: Adenovirus 5 E1A enhances histone deacetylase inhibitors-induced apoptosis through Egr-1-mediated Bim upregulation. Oncogene 29: 5619-5629, 2010.
-
(2010)
Oncogene
, vol.29
, pp. 5619-5629
-
-
Yamaguchi, H.1
Chen, C.T.2
Chou, C.K.3
Pal, A.4
Bornmann, W.5
Hortobagyi, G.N.6
Hung, M.C.7
-
10
-
-
76949102583
-
Early growth response-1 is a regulator of DR5-induced apoptosis in colon cancer cells
-
Mahalingam D, Natoni A, Keane M, Samali A and Szegezdi E: Early growth response-1 is a regulator of DR5-induced apoptosis in colon cancer cells. Br J Cancer 102: 754-764, 2010.
-
(2010)
Br J Cancer
, vol.102
, pp. 754-764
-
-
Mahalingam, D.1
Natoni, A.2
Keane, M.3
Samali, A.4
Szegezdi, E.5
-
11
-
-
39649102735
-
Transcriptional regulation of human survivin by early growth response (Egr)-1 transcription factor
-
DOI 10.1002/ijc.23183
-
Wagner M, Schmelz K, Dorken B and Tamm I: Transcriptional regulation of human survivin by early growth response (Egr)-1 transcription factor. Int J Cancer 122: 1278-1287, 2008. (Pubitemid 351287227)
-
(2008)
International Journal of Cancer
, vol.122
, Issue.6
, pp. 1278-1287
-
-
Wagner, M.1
Schmelz, K.2
Dorken, B.3
Tamm, I.4
-
12
-
-
61349089170
-
EGR-1 forms a complex with YAP-1 and upregulates Bax expresion in irradiated prostate carcinoma cells
-
Zagurovskaya M, Shareef MM, Das A, Reeves A, Gupta S, Sudol M, Bedford MT, Prichard J, Mohiuddin M and Ahmed MM: EGR-1 forms a complex with YAP-1 and upregulates Bax expresion in irradiated prostate carcinoma cells. Oncogene 28: 1121-1131, 2009.
-
(2009)
Oncogene
, vol.28
, pp. 1121-1131
-
-
Zagurovskaya, M.1
Shareef, M.M.2
Das, A.3
Reeves, A.4
Gupta, S.5
Sudol, M.6
Bedford, M.T.7
Prichard, J.8
Mohiuddin, M.9
Ahmed, M.M.10
-
13
-
-
1542514781
-
Regulation of radiation-induced apoptosis by early growth response-1 gene in solid tumors
-
DOI 10.2174/1568009043481704
-
Ahmed MM: Regulation of radiation-induced apoptosis by early growth response-1 gene in solid tumors. Curr Cancer Drug Targets 4: 43-52, 2004. (Pubitemid 38332563)
-
(2004)
Current Cancer Drug Targets
, vol.4
, Issue.1
, pp. 43-52
-
-
Ahmed, M.M.1
-
14
-
-
30944446390
-
The transcription factor Egr1 is a direct regulator of multiple tumor suppressors including TGFβ1, PTEN, p53, and fibronectin
-
DOI 10.1038/sj.cgt.7700896, PII 7700896
-
Baron V, Adamson ED, Calogero A, Ragona G and Mercola D: The transcription factor Egr1 is a direct regulator of multiple tumor suppressors including TGFbeta1, PTEN, p53, and fibronectin. Cancer Gene Ther 13: 115-124, 2006. (Pubitemid 43113412)
-
(2006)
Cancer Gene Therapy
, vol.13
, Issue.2
, pp. 115-124
-
-
Baron, V.1
Adamson, E.D.2
Calogero, A.3
Ragona, G.4
Mercola, D.5
-
15
-
-
33746925159
-
Early growth response gene-1 regulates hypoxia-induced expression of tissue factor in glioblastoma multiforme through hypoxia-inducible factor-1-independent mechanisms
-
DOI 10.1158/0008-5472.CAN-06-0346
-
Rong Y, Hu F, Huang R, Mackman N, Horowitz JM, Jensen RL, Durden DL, Van Meir EG and Brat DJ: Early growth response gene-1 regulates hypoxia-induced expression of tissue factor in glioblastoma multiforme through hypoxia-inducible factor-1-independent mechanisms. Cancer Res 66: 7067-7074, 2006. (Pubitemid 44197683)
-
(2006)
Cancer Research
, vol.66
, Issue.14
, pp. 7067-7074
-
-
Rong, Y.1
Hu, F.2
Huang, R.3
Mackman, N.4
Horowitz, J.M.5
Jensen, R.L.6
Durden, D.L.7
Van Meir, E.G.8
Brat, D.J.9
-
16
-
-
33847373884
-
Molecular regulation of the PAI-1 gene by hypoxia: Contributions of Egr-1, HIF-1α, and C/EBPα
-
DOI 10.1096/fj.06-6285com
-
Liao H, Hyman MC, Lawrence DA and Pinsky DJ: Molecular regulation of the PAI-1 gene by hypoxia: contributions of Egr-1, HIF-1alpha, and C/EBPalpha. FASE B J 21: 935-949, 2007. (Pubitemid 46348266)
-
(2007)
FASEB Journal
, vol.21
, Issue.3
, pp. 935-949
-
-
Liao, H.1
Hyman, M.C.2
Lawrence, D.A.3
Pinsky, D.J.4
-
17
-
-
35148883007
-
Egr-1 mediates hypoxia-inducible transcription of the NDRG1 gene through an overlapping Egr-1/Sp1 binding site in the promoter
-
DOI 10.1158/0008-5472.CAN-07-1525
-
Zhang P, Tchou-Wong KM and Costa M: Egr-1 mediates hypoxia-inducible transcription of the NDRG1 gene through an overlapping Egr-1/Sp1 binding site in the promoter. Cancer Res 67: 9125-9133, 2007. (Pubitemid 47535898)
-
(2007)
Cancer Research
, vol.67
, Issue.19
, pp. 9125-9133
-
-
Zhang, P.1
Tchou-Wong, K.-M.2
Costa, M.3
-
18
-
-
0036468259
-
Early growth response-1 gene mediates up-regulation of epidermal growth factor receptor expression during hypoxia
-
Nishi H, Nishi KH and Johnson AC: Early growth response-1 gene mediates up-regulation of epidermal growth factor receptor expression during hypoxia. Cancer Res 62: 827-834, 2002. (Pubitemid 34126960)
-
(2002)
Cancer Research
, vol.62
, Issue.3
, pp. 827-834
-
-
Nishi, H.1
Nishi, K.H.2
Johnson, A.C.3
-
19
-
-
33747625686
-
Hepatocyte growth factor induces cell scattering through MAPK/Egr-1-mediated upregulation of Snail
-
DOI 10.1038/sj.emboj.7601213, PII 7601213
-
Grotegut S, von Schweinitz D, Christofori G and Lehembre F: Hepatocyte growth factor induces cell scattering through MAPK/Egr-1-mediated upregulation of Snail. EMBO J 25: 3534-3545, 2006. (Pubitemid 44264864)
-
(2006)
EMBO Journal
, vol.25
, Issue.15
, pp. 3534-3545
-
-
Grotegut, S.1
Von Schweinitz, D.2
Christofori, G.3
Lehembre, F.4
-
20
-
-
33746119582
-
Sustained expression of early growth response protein-1 blocks angiogenesis and tumor growth
-
DOI 10.1158/0008-5472.CAN-05-2732
-
Lucerna M, Pomyje J, Mechtcheriakova D, Kadl A, Gruber F, Bilban M, Sobanov Y, Schabbauer G, Breuss J, Wagner O, Bischoff M, Clauss M, Binder BR and Hofer E: Sustained expression of early growth response protein-1 blocks angiogenesis and tumor growth. Cancer Res 66: 6708-6713, 2006. (Pubitemid 44085628)
-
(2006)
Cancer Research
, vol.66
, Issue.13
, pp. 6708-6713
-
-
Lucerna, M.1
Pomyje, J.2
Mechtcheriakova, D.3
Kadl, A.4
Gruber, F.5
Bilban, M.6
Sobanov, Y.7
Schabbauer, G.8
Breuss, J.9
Wagner, O.10
Bischoff, M.11
Clauss, M.12
Binder, B.R.13
Hofer, E.14
-
21
-
-
34147223377
-
Protein kinase C-ERK1/2 signal pathway switches glucose depletion-induced necrosis to apoptosis by regulating superoxide dismutases and suppressing reactive oxygen species production in A549 lung cancer cells
-
DOI 10.1002/jcp.20941
-
Kim CH, Han SI, Lee SY, Youk HS, Moon JY, Duong HQ, Park MJ, Joo YM, Park HG, Kim YJ, Yoo MA, Lim SC and Kang HS: Protein kinase C-ERK1/2 signal pathway switches glucose depletion-induced necrosis to apoptosis by regulating superoxide dismutases and suppressing reactive oxygen species production in A549 lung cancer cells. J Cell Physiol 211: 371-385, 2007. (Pubitemid 46580091)
-
(2007)
Journal of Cellular Physiology
, vol.211
, Issue.2
, pp. 371-385
-
-
Kim, C.H.1
Han, S.I.2
Lee, S.Y.3
Youk, H.S.4
Moon, J.Y.5
Duong, H.Q.6
Park, M.J.7
Joo, Y.M.8
Park, H.G.9
Kim, Y.J.10
Yoo, M.A.11
Lim, S.-C.12
Kang, H.S.13
-
22
-
-
79952976450
-
Implication of snail in metabolic stress-induced necrosis
-
Kim CH, Jeon HM, Lee SY, Ju MK, Moon JY, Park HG, Yoo MA, Choi BT, Yook JI, Lim SC, Han SI and Kang HS: Implication of snail in metabolic stress-induced necrosis. PLoS One 6: e18000, 2011.
-
(2011)
PLoS One
, vol.6
-
-
Kim, C.H.1
Jeon, H.M.2
Lee, S.Y.3
Ju, M.K.4
Moon, J.Y.5
Park, H.G.6
Yoo, M.A.7
Choi, B.T.8
Yook, J.I.9
Lim, S.C.10
Han, S.I.11
Kang, H.S.12
-
23
-
-
1642359043
-
Microenvironmental Regulation of Proliferation in Multicellular Spheroids Is Mediated through Differential Expression of Cyclin-Dependent Kinase Inhibitors
-
DOI 10.1158/0008-5472.CAN-2902-2
-
LaRue KE, Khalil M and Freyer JP: Microenvironmental regulation of proliferation in multicellular spheroids is mediated through differential expression of cyclin-dependent kinase inhibitors. Cancer Res 64: 1621-1631, 2004. (Pubitemid 38428682)
-
(2004)
Cancer Research
, vol.64
, Issue.5
, pp. 1621-1631
-
-
LaRue, K.E.A.1
Khalil, M.2
Freyer, J.P.3
-
24
-
-
0029977426
-
Functional activation of the egr-1 (early growth response-1) gene by hydrogen peroxide
-
Nose K and Ohba M: Functional activation of the egr-1 (early growth response-1) gene by hydrogen peroxide. Biochem J 316: 381-383, 1996. (Pubitemid 26182130)
-
(1996)
Biochemical Journal
, vol.316
, Issue.2
, pp. 381-383
-
-
Nose, K.1
Ohba, M.2
-
25
-
-
44449102801
-
Hyperthermia switches glucose depletion-induced necrosis to apoptosis in A549 lung adenocarcinoma cells
-
Han SI, Duong HQ, Choi JE, Lee TB, Kim CH, Lee SY, Jeon HM, Shin SH, Lim SC and Kang HS: Hyperthermia switches glucose depletion-induced necrosis to apoptosis in A549 lung adenocarcinoma cells. Int J Oncol 32: 851-860, 2008. (Pubitemid 351780595)
-
(2008)
International Journal of Oncology
, vol.32
, Issue.4
, pp. 851-860
-
-
Han, S.I.1
Duong, H.-Q.2
Choi, J.E.3
Lee, T.-B.4
Kim, C.H.5
Lee, S.Y.6
Jeon, H.M.7
Shin, S.-H.8
Lim, S.-C.9
Kang, H.S.10
-
26
-
-
20044361991
-
2 mediate glucose deprivation-induced cytotoxicity and oxidative stress in human cancer cells
-
DOI 10.1074/jbc.M411662200
-
2 mediate glucose deprivation-induced stress in human cancer cells. J Biol Chem 280: 4254-4263, 2005. (Pubitemid 40288592)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.6
, pp. 4254-4263
-
-
Ahmad, I.M.1
Aykin-Burns, N.2
Sim, J.E.3
Walsh, S.A.4
Higashikubo, R.5
Buettner, G.R.6
Venkataraman, S.7
Mackey, M.A.8
Flanagan, S.W.9
Oberley, L.W.10
Spitz, D.R.11
-
27
-
-
0034038708
-
Glucose deprivation-induced oxidative stress in human tumor cells. A fundamental defect in metabolism?
-
Spitz DR, Sim JE, Ridnour LA, Galoforo SS and Lee YJ: Glucose deprivation-induced oxidative stress in human tumor cells. A fundamental defect in metabolism? Ann NY Acad Sci 899: 349-362, 2000. (Pubitemid 30352799)
-
(2000)
Annals of the New York Academy of Sciences
, vol.899
, pp. 349-362
-
-
Spitz, D.R.1
Sim, J.E.2
Ridnour, L.A.3
Galoforo, S.S.4
Lee, Y.J.5
-
29
-
-
29944438881
-
Necrotic death as a cell fate
-
DOI 10.1101/gad.1376506
-
Zong WX and Thompson CB: Necrotic death as a cell fate. Genes Dev 20: 1-15, 2006. (Pubitemid 43042662)
-
(2006)
Genes and Development
, vol.20
, Issue.1
, pp. 1-15
-
-
Zong, W.-X.1
Thompson, C.B.2
-
30
-
-
33846018602
-
Cell death by necrosis: Towards a molecular definition
-
DOI 10.1016/j.tibs.2006.11.001, PII S0968000406003185
-
Golstein P and Kroemer G: Cell death by necrosis: towards a molecular definition. Trends Biochem Sci 32: 37-43, 2007. (Pubitemid 46043552)
-
(2007)
Trends in Biochemical Sciences
, vol.32
, Issue.1
, pp. 37-43
-
-
Golstein, P.1
Kroemer, G.2
-
31
-
-
56049090579
-
3-D tumor model for in vitro evaluation of anticancer drugs
-
Horning JL, Sahoo SK, Vijayaraghavalu S, Dimitrijevic S, Vasir JK, Jain TK, Panda AK and Labhasetwar V: 3-D tumor model for in vitro evaluation of anticancer drugs. Mol Pharm 5: 849-862, 2008.
-
(2008)
Mol Pharm
, vol.5
, pp. 849-862
-
-
Horning, J.L.1
Sahoo, S.K.2
Vijayaraghavalu, S.3
Dimitrijevic, S.4
Vasir, J.K.5
Jain, T.K.6
Panda, A.K.7
Labhasetwar, V.8
-
32
-
-
38449101699
-
Diversity of cell-mediated adhesions in breast cancer spheroids
-
Ivascu A and Kubbies M: Diversity of cell-mediated adhesions in breast cancer spheroids. Int J Oncol 31: 1403-1413, 2007.
-
(2007)
Int J Oncol
, vol.31
, pp. 1403-1413
-
-
Ivascu, A.1
Kubbies, M.2
-
33
-
-
77956510367
-
Role of extracellular signal-regulated kinase (ERK)1/2 in multi-cellular resistance to docetaxel in MCF-7 cells
-
Jeong EK, Lee SY, Jeon HM, Ju MK, Kim CH and Kang HS: Role of extracellular signal-regulated kinase (ERK)1/2 in multi-cellular resistance to docetaxel in MCF-7 cells. Int J Oncol 37: 655 - 661, 2010.
-
(2010)
Int J Oncol
, vol.37
, pp. 655-661
-
-
Jeong, E.K.1
Lee, S.Y.2
Jeon, H.M.3
Ju, M.K.4
Kim, C.H.5
Kang, H.S.6
-
34
-
-
0034596947
-
Reactive oxygen species (ROS)-induced ROS release: A new phenomenon accompanying induction of the mitochondrial permeability transition in cardiac myocytes
-
Zorov DB, Filburn CR, Klotz LO, Zweier JL and Sollott SJ: Reactive oxygen species (ROS)-induced ROS release: a new phenomenon accompanying induction of the mitochondrial permeability transition in cardiac myocytes. J Exp Med 192: 1001-1014, 2000.
-
(2000)
J Exp Med
, vol.192
, pp. 1001-1014
-
-
Zorov, D.B.1
Filburn, C.R.2
Klotz, L.O.3
Zweier, J.L.4
Sollott, S.J.5
-
35
-
-
33745684904
-
Mitochondrial ROS-induced ROS release: An update and review
-
Zorov DB, Juhaszova M and Sollott SJ: Mitochondrial ROS-induced ROS release: an update and review. Biochim Biophys Acta 1757: 509-517, 2006.
-
(2006)
Biochim Biophys Acta
, vol.1757
, pp. 509-517
-
-
Zorov, D.B.1
Juhaszova, M.2
Sollott, S.J.3
-
36
-
-
2642536197
-
Alkylating DNA damage stimulates a regulated form of necrotic cell death
-
DOI 10.1101/gad.1199904
-
Zong WX, Ditsworth D, Bauer DE, Wang ZQ and Thompson CB: Alkylating DNA damage stimulates a regulated form of necrotic cell death. Genes Dev 18: 1272-1282, 2004. (Pubitemid 38720595)
-
(2004)
Genes and Development
, vol.18
, Issue.11
, pp. 1272-1282
-
-
Zong, W.-X.1
Ditsworth, D.2
Bauer, D.E.3
Wang, Z.-Q.4
Thompson, C.B.5
-
37
-
-
80052849532
-
Homeobox gene Dlx-2 is implicated in metabolic stress-induced necrosis
-
Lee SY, Jeon HM, Kim CH, Ju MK, Bae HS, Park HG, Lim SC, Han SI and Kang HS: Homeobox gene Dlx-2 is implicated in metabolic stress-induced necrosis. Mol Cancer 10: 113, 2011.
-
(2011)
Mol Cancer
, vol.10
, pp. 113
-
-
Lee, S.Y.1
Jeon, H.M.2
Kim, C.H.3
Ju, M.K.4
Bae, H.S.5
Park, H.G.6
Lim, S.C.7
Han, S.I.8
Kang, H.S.9
-
38
-
-
84863917176
-
Wnt/Snail signaling regulates cytochrome C oxidase and glucose metabolism
-
Lee SY, Jeon HM, Ju MK, Kim CH, Yoon G, Han SI, Park HG and Kang HS: Wnt/Snail signaling regulates cytochrome C oxidase and glucose metabolism. Cancer Res 72: 3607-3617, 2012.
-
(2012)
Cancer Res
, vol.72
, pp. 3607-3617
-
-
Lee, S.Y.1
Jeon, H.M.2
Ju, M.K.3
Kim, C.H.4
Yoon, G.5
Han, S.I.6
Park, H.G.7
Kang, H.S.8
|