Targeting MCT-1 oncogene inhibits Shc pathway and xenograft tumorigenicity

Oncotarget

Volumn 3, Issue 11, 2012, Pages 1401-1415

  Shih, Hung Ju ^a,b   Chen, Hsiao Huei ^a   Chen, Yen An ^a   Wu, Meng Hsun ^a   Liou, Gan Guang ^a   Chang, Wei Wen ^b   Chen, Linyi ^c   Wang, Lu Hai ^a   Hsu, Hsin Ling ^a  

^a NATIONAL HEALTH RESEARCH INSTITUTES   (Taiwan)

^b TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^c NATIONAL TSING HUA UNIVERSITY   (Taiwan)

Author keywords

Apoptosis; ERK; MCT 1; Ras; Shc; Tumor.

Indexed keywords

BETA4 INTEGRIN; CAMPTOTHECIN; CASPASE 3; CASPASE 7; CYCLIN D1; DOXORUBICIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE KINASE; MULTIPLE COPIES IN T CELL MALIGNANCY 1 PROTEIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; ONCOPROTEIN; PROTEIN P46; PROTEIN P52; PROTEIN P53; PROTEIN P66; PROTEIN SHC; RAS PROTEIN; RETINOBLASTOMA PROTEIN; SHORT HAIRPIN RNA; TUMOR MARKER; UNCLASSIFIED DRUG; VIMENTIN;

ANCHORAGE INDEPENDENT GROWTH; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER CELL; CANCER INHIBITION; CANCER STAGING; CARCINOGENICITY; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; DRUG RESISTANCE; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; ENZYME SUBSTRATE; FEMALE; GENE ACTIVATION; GENE EXPRESSION; GENE INDUCTION; GENE SILENCING; GENE TARGETING; GENETIC ASSOCIATION; HUMAN; HUMAN CELL; IN VITRO STUDY; INTRACELLULAR SIGNALING; LOSS OF FUNCTION MUTATION; LUNG CARCINOMA; MOLECULAR INTERACTION; MOUSE; MULTIPLE COPIES IN T CELL MALIGNANCY 1 GENE; NONHUMAN; ONCOGENE; PROTEIN CLEAVAGE; SRC HOMOLOG AND COLLAGEN HOMOLOG GENE; TUMOR XENOGRAFT;

EID: 84872798883     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.688     Document Type: Article

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