Optimization of thermosensitive chitosan hydrogels for the sustained delivery of venlafaxine hydrochloride

International Journal of Pharmaceutics

Volumn 441, Issue 1-2, 2013, Pages 482-490

  Peng, Ying ^a   Li, Jie ^a   Li, Jing ^a   Fei, Yin ^b   Dong, Jiangnan ^b   Pan, Weisan ^a  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

^b Liaoning Cancer Hospital and Institute   (China)

Author keywords

Box Behnken design; Chitosan; Glycerophosphate disodium; Release mechanism; Thermosensitive hydrogel; Venlafaxine

Indexed keywords

CHITOSAN; VENLAFAXINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG MECHANISM; DRUG RELEASE; DRUG SOLUBILITY; FEMALE; HEAT SENSITIVITY; HYDROGEL; IN VIVO STUDY; MALE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; CHITOSAN; CYCLOHEXANOLS; DELAYED-ACTION PREPARATIONS; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; FEMALE; GLYCEROPHOSPHATES; HYDROGELS; MALE; MODELS, THEORETICAL; RABBITS; SEROTONIN UPTAKE INHIBITORS; TEMPERATURE; TIME FACTORS;

EID: 84872794887     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2012.11.005     Document Type: Article

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