Key parameters affecting the initial release (burst) and encapsulation efficiency of peptide-containing poly(lactide-co-glycolide) microparticles

International Journal of Pharmaceutics

Volumn 324, Issue 2, 2006, Pages 168-175

  Luan, Xiaosong ^a   Skupin, Marc ^a   Siepmann, Jürgen ^a   Bodmeier, Roland ^a  

^a FREIE UNIVERSITÄT BERLIN   (Germany)

Author keywords

Burst; Encapsulation efficiency; Initial release; Microencapsulation; Poly(lactide co glycolide); Scale up; Solvent evaporation method

Indexed keywords

ALCOHOL; LEUPRORELIN; PEPTIDE; POLYGLACTIN; POLYMER; RESOMER; SODIUM CHLORIDE;

AQUEOUS SOLUTION; ARTICLE; CHEMICAL PARAMETERS; DRUG RELEASE; EVAPORATION; MICROENCAPSULATION; PARTICLE SIZE; POROSITY; PRECIPITATION; PRIORITY JOURNAL; SCALE UP;

DELAYED-ACTION PREPARATIONS; ETHANOL; LACTIC ACID; LEUPROLIDE; PARTICLE SIZE; POLYGLYCOLIC ACID; POLYMERS; SODIUM CHLORIDE; VOLATILIZATION;

EID: 33749517493     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2006.06.004     Document Type: Article

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