Association between BDNF rs6265 and obesity in the Boston Puerto Rican Health Study

Journal of Obesity

Volumn 2012, Issue , 2012, Pages

  Ma, Xian Yong ^a,b   Qiu, Wei Qiao ^c   Smith, Caren E ^b   Parnell, Laurence D ^b   Jiang, Zong Yong ^a   Ordovas, Jose M ^b   Tucker, Katherine L ^d   Lai, Chao Qiang ^b  

^a INSTITUTE OF ANIMAL SCIENCE   (China)

^b TUFTS UNIVERSITY   (United States)

^c BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d NORTHEASTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; OMEGA 3 FATTY ACID; OMEGA 6 FATTY ACID; POLYUNSATURATED FATTY ACID; UNSATURATED FATTY ACID;

ADULT; AGED; ARTICLE; BODY MASS; BODY WEIGHT; CONTROLLED STUDY; DIETARY INTAKE; FEMALE; FOOD FREQUENCY QUESTIONNAIRE; FOOD INTAKE; GENE EXPRESSION; GENETIC ASSOCIATION; GENETIC TRAIT; GENETIC VARIABILITY; GENOTYPE; HIP CIRCUMFERENCE; HUMAN; MAJOR CLINICAL STUDY; MALE; OBESITY; PUERTO RICO; RISK FACTOR; SEX DIFFERENCE; SINGLE NUCLEOTIDE POLYMORPHISM; WAIST CIRCUMFERENCE; DIET; ETHNOLOGY; GENETICS; MIDDLE AGED; UNITED STATES;

AGED; BODY MASS INDEX; BOSTON; BRAIN-DERIVED NEUROTROPHIC FACTOR; DIET; FATTY ACIDS, UNSATURATED; FEMALE; GENOTYPE; HUMANS; MALE; MIDDLE AGED; OBESITY; POLYMORPHISM, SINGLE NUCLEOTIDE; PUERTO RICO;

MLCS; MLOWN;

EID: 84872780066     PISSN: 20900708     EISSN: 20900716     Source Type: Journal    
DOI: 10.1155/2012/102942     Document Type: Article

References (37)

1. Christakis N. A., Fowler J. H., The spread of obesity in a large social network over 32 years. The New England Journal of Medicine 2007 357 4 370 379 2-s2.0-34547170053 10.1056/NEJMsa066082 (Pubitemid 47124137)
2. Maes H. H. M., Neale M. C., Eaves L. J., Genetic and environmental factors in relative body weight and human adiposity. Behavior Genetics 1997 27 4 325 351 2-s2.0-0030843960 10.1023/A:1025635913927 (Pubitemid 27415169)
3. Monteleone P., Tortorella A., Martiadis V., Serritella C., Fuschino A., Maj M., Opposite changes in the serum brain-derived neurotrophic factor in anorexia nervosa and obesity. Psychosomatic Medicine 2004 66 5 744 748 2-s2.0-4944248818 10.1097/01.psy.0000138119.12956.99 (Pubitemid 39332362)
4. El-Gharbawy A. H., Adler-Wailes D. C., Mirch M. C., Theim K. R., Ranzenhofer L., Tanofsky-Kraff M., Yanovski J. A., Serum brain-derived neurotrophic factor concentrations in lean and overweight children and adolescents. Journal of Clinical Endocrinology and Metabolism 2006 91 9 3548 3552 2-s2.0-33748741883 10.1210/jc.2006-0658 (Pubitemid 44402136)
5. Lyons W., Mamounas L. A., Ricaurte G. A., Coppola V., Reid S. W., Bora S. H., Wihler C., Koliatsos V. E., Tessarollo L., Brain-derived neurotrophic factor-deficient mice develop aggressiveness and hyperphagia in conjunction with brain serotonergic abnormalities. Proceedings of the National Academy of Sciences of the United States of America 1999 96 26 15239 15244 2-s2.0-0033592920 10.1073/pnas.96.26.15239 (Pubitemid 30019796)
6. Rios M., Fan G., Fekete C., Kelly J., Bates B., Kuehn R., Lechan R. M., Jaenisch R., Conditional deletion of brain-derived neurotrophic factor in the postnatal brain leads to obesity and hyperactivity. Molecular Endocrinology 2001 15 10 1748 1757 2-s2.0-0034792085 10.1210/me.15.10.1748 (Pubitemid 32939305)
7. Cao L., Choi E. Y., Liu X. L., White to brown fat phenotypic switch induced by genetic and environmental activation of a hypothalamic-adipocyte axis. Cell Metabolism 2011 14 324 338
8. Krabbe K. S., Nielsen A. R., Krogh-Madsen R., Brain derived neurotrophic factor (BDNF) and type 2 diabetes. Diabetologia 2007 50 431 438
9. Yeo G. S. H., Hung C. C. C., Rochford J., Keogh J., Gray J., Sivaramakrishnan S., O'Rahilly S., Farooqi I. S., A de novo mutation affecting human TrkB associated with severe obesity and developmental delay. Nature Neuroscience 2004 7 11 1187 1189 2-s2.0-7044262828 10.1038/nn1336 (Pubitemid 39426236)
10. Yu Y., Wang Q., Huang X. F., Energy-restricted pair-feeding normalizes low levels of brain-derived neurotrophic factor/tyrosine kinase B mRNA expression in the hippocampus, but not ventromedial hypothalamic nucleus, in diet-induced obese mice. Neuroscience 2009 160 2 295 306 2-s2.0-64049109087 10.1016/j.neuroscience.2009.01.078
11. Friedel S., Horro F. F., Wermter A. K., Geller F., Dempfle A., Reichwald K., Smidt J., Brönner G., Konrad K., Herpertz-Dahlmann B., Warnke A., Hemminger U., Linder M., Kiefl H., Goldschmidt H. P., Siegfried W., Remschmldt H., Hinney A., Hebebrand J., Mutation screen of the brain derived neurotrophic factor gene (BDNF): identification of several genetic variants and association studies in patients with obesity, eating disorders, and attention-deficit/ hyperactivity disorder. American Journal of Medical Genetics 2005 132 1 96 99 2-s2.0-19944429689 10.1002/ajmg.b.30090 (Pubitemid 40066204)
12. Ribasés M., Gratacòs M., Fernández-Aranda F., Association of BDNF with anorexia, bulimia and age of onset of weight loss in six European populations. Human Molecular Genetics 2004 13 1205 1212 (Pubitemid 38877873)
13. Beckers S., Peeters A., Zegers D., Mertens I., Gaal L. V., Van Hul W., Association of the BDNF Val66Met variation with obesity in women. Molecular Genetics and Metabolism 2008 95 1-2 110 112 2-s2.0-51849117596 10.1016/j.ymgme.2008.06.008
14. Gunstad J., Schofield P., Paul R. H., Spitznagel M. B., Cohen R. A., Williams L. M., Kohn M., Gordon E., BDNF Val66Met polymorphism is associated with body mass index in healthy adults. Neuropsychobiology 2006 53 3 153 156 2-s2.0-33744958340 10.1159/000093341 (Pubitemid 43854175)
15. Zhao J., Bradfield J. P., Li M., Wang K., Zhang H., Kim C. E., Annaiah K., Glessner J. T., Thomas K., Garris M., Frackelton E. C., Otieno F. G., Shaner J. L., Smith R. M., Chiavacci R. M., Berkowitz R. I., Hakonarson H., Grant S. F. A., The role of obesity-associated loci identified in genome-wide association studies in the determination of pediatric BMI. Obesity 2009 17 12 2254 2257 2-s2.0-72449169954 10.1038/oby.2009.159
16. Chen Z. Y., Patel P. D., Sant G., Meng C. X., Teng K. K., Hempstead B. L., Lee F. S., Variant brain-derived neurotrophic factor (BDNF) (Met66) alters the intracellular trafficking and activity-dependent secretion of wild-type BDNF in neurosecretory cells and cortical neurons. Journal of Neuroscience 2004 24 18 4401 4411 2-s2.0-2342550552 10.1523/JNEUROSCI.0348-04.2004 (Pubitemid 38608151)
17. Egan M. F., Kojima M., Callicott J. H., Goldberg T. E., Kolachana B. S., Bertolino A., Zaitsev E., Gold B., Goldman D., Dean M., Lu B., Weinberger D. R., The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function. Cell 2003 112 2 257 269 2-s2.0-0037462449 10.1016/S0092-8674(03)00035-7 (Pubitemid 36144114)
18. Tucker K. L., Stress and nutrition in relation to excess development of chronic disease in Puerto Rican adults living in the Northeastern USA. Journal of Medical Investigation 2005 52 252 258 2-s2.0-30144443451 10.2152/jmi.52.252 (Pubitemid 43051884)
19. Lai C. Q., Tucker K. L., Parnell L. D., Adiconis X., García-Bailo B., Griffith J., Meydani M., Ordováls J. M., PPARGC1A variation associated with DNA damage, diabetes, and cardiovascular diseases the boston puerto rican health study. Diabetes 2008 57 4 809 816 2-s2.0-42449113349 10.2337/db07-1238
20. Tucker K. L., Bianchi L. A., Maras J., Bermudez O. I., Adaptation of a food frequency questionnaire to assess diets of Puerto Rican and non-Hispanic adults. American Journal of Epidemiology 1998 148 5 507 518 2-s2.0-0032169522 (Pubitemid 28411108)
21. Tucker K. L., Mattei J., Noel S. E., Collado B. M., Mendez J., Nelson J., Griffith J., Ordovas J. M., Falcon L. M., The Boston Puerto Rican health study, a longitudinal cohort study on health disparities in Puerto Rican adults: challenges and opportunities. BMC Public Health 2010 10, article 107 2-s2.0-77950570673 10.1186/1471-2458-10-107
22. Lai C. Q., Tucker K. L., Choudhry S., Parnell L. D., Mattei J., García-Bailo B., Beckman K., Burchard E. G., Ordovás J. M., Population admixture associated with disease prevalence in the Boston Puerto Rican health study. Human Genetics 2009 125 2 199 209 2-s2.0-60549098050 10.1007/s00439-008-0612-7
23. Li J., Ji L., Adjusting multiple testing in multilocus analyses using the eigenvalues of a correlation matrix. Heredity 2005 95 3 221 227 2-s2.0-30744434862 10.1038/sj.hdy.6800717 (Pubitemid 43093236)
24. Maisonpierre P. C., Belluscio L., Friedman B., Alderson R. F., Wiegand S. J., Furth M. E., Lindsay R. M., Yancopoulos G. D., NT-3, BDNF, and NGF in the developing rat nervous system: parallel as well as reciprocal patterns of expression. Neuron 1990 5 4 501 509 2-s2.0-0025119187 10.1016/0896-6273(90) 90089-X (Pubitemid 20369586)
25. Kernie S. G., Liebl D. J., Parada L. F., BDNF regulates eating behavior and locomotor activity in mice. The EMBO Journal 2000 19 6 1290 1300 2-s2.0-0034653422 (Pubitemid 30151025)
26. Pedersen B. K., Pedersen M., Krabbe K. S., Bruunsgaard H., Matthews V. B., Febbraio M. A., Role of exercise-induced brain-derived neurotrophic factor production in the regulation of energy homeostasis in mammals. Experimental Physiology 2009 94 12 1153 1160 2-s2.0-73149116208 10.1113/expphysiol.2009. 048561
27. Zhang X. Y., Zhou D. F., Wu G. Y., Cao L. Y., Tan Y. L., Haile C. N., Li J., Lu L., Kosten T. A., Kosten T. R., BDNF levels and genotype are associated with antipsychotic-induced weight gain in patients with chronic schizophrenia. Neuropsychopharmacology 2008 33 9 2200 2205 2-s2.0-47249138191 10.1038/sj.npp.1301619 (Pubitemid 351992089)
28. Akkermann K., Hiio K., Villa I., Harro J., Food restriction leads to binge eating dependent upon the effect of the brain-derived neurotrophic factor Val66Met polymorphism. Psychiatry Research 2011 185 1-2 39 43 2-s2.0-78650190642 10.1016/j.psychres.2010.04.024
29. Shugart Y. Y., Chen L., Day I. N. M., Lewis S. J., Timpson N. J., Yuan W., Abdollahi M. R., Ring S. M., Ebrahim S., Golding J., Lawlor D. A., Davey-Smith G., Two British women studies replicated the association between the Val66Met polymorphism in the brain-derived neurotrophic factor (BDNF) and BMI. European Journal of Human Genetics 2009 17 8 1050 1055 2-s2.0-67749120339 10.1038/ejhg.2008.272
30. Arija V., Ferrer-Barcala M., Aranda N., Canals J., BDNF Val66Met polymorphism, energy intake and BMI: a follow-up study in schoolchildren at risk of eating disorders. BMC Public Health 2010 10, article 363 2-s2.0-77953718860 10.1186/1471-2458-10-363
31. van Oostrom I., Franke B., Rijpkema M., Interaction between BDNF Val66Met and childhood stressful life events is associated to affective memory bias in men but not women. Biological Psychology 2012 89 1 214 219
32. Ono M., Itakura Y., Nonomura T., Nakagawa T., Nakayama C., Taiji M., Noguchi H., Intermittent administration of brain-derived neurotrophic factor ameliorates glucose metabolism in obese diabetic mice. Metabolism 2000 49 1 129 133 2-s2.0-0033963228 (Pubitemid 30054045)
33. Tonra J. R., Ono M., Liu X., Garcia K., Jackson C., Yancopoulos G. D., Wiegand S. J., Wong V., Brain-derived neurotrophic factor improves blood glucose control and alleviates fasting hyperglycemia in C57BLKS- lepr db / lepr db mice. Diabetes 1999 48 3 588 594 2-s2.0-0033005143 (Pubitemid 29106874)
34. Pelleymounter M. A., Cullen M. J., Wellman C. L., Characteristics of BDNF-induced weight loss. Experimental Neurology 1995 131 2 229 238 2-s2.0-0028946958
35. Xu B., Goulding E. H., Zang K., Cepoi D., Cone R. D., Jones K. R., Tecott L. H., Reichardt L. F., Brain-derived neurotrophic factor regulates energy balance downstream of melanocortin-4 receptor. Nature Neuroscience 2003 6 7 736 742 2-s2.0-0038392755 10.1038/nn1073 (Pubitemid 36792889)
36. Rapoport S. I., Rao J. S., Igarashi M., Brain metabolism of nutritionally essential polyunsaturated fatty acids depends on both the diet and the liver. Prostaglandins Leukotrienes and Essential Fatty Acids 2007 77 5-6 251 261 2-s2.0-36749082536 10.1016/j.plefa.2007.10.023 (Pubitemid 350214520)
37. 1A receptors in fish oil-mediated increased BDNF expression in the rat hippocampus and cortex: a possible antidepressant mechanism. Neuropharmacology 2012 62 1 184 191