Protective effect of Moringa oleifera leaves against gentamicin-induced nephrotoxicity in rabbits

Experimental and Toxicologic Pathology

Volumn 65, Issue 3, 2013, Pages 335-339

  Ouédraogo, Moustapha ^a,c   Lamien Sanou, Assita ^b   Ramdé, Norbert ^b   Ouédraogo, Aimé S ^b   Ouédraogo, Moussa ^a   Zongo, Salifou P ^a   Goumbri, Olga ^b   Duez, Pierre ^c,d   Guissou, Pierre I ^a  

^a UNIVERSITÉ DE OUAGADOUGOU   (Burkina Faso)

^b University Hospital Yalgado Ouedraogo   (Burkina Faso)

^c UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

^d UNIVERSITY OF MONS   (Belgium)

Author keywords

Gentamicin; Lipid peroxidation; Moringa oleifera; Nephroprotection; Nephrotoxicity

Indexed keywords

ALANINE AMINOTRANSFERASE; ALCOHOL; ASPARTATE AMINOTRANSFERASE; CREATININE; GENTAMICIN; MORINGA OLEIFERA EXTRACT; REACTIVE OXYGEN METABOLITE; THIOBARBITURIC ACID REACTIVE SUBSTANCE; UREA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; AQUEOUS SOLUTION; ARTICLE; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DOSE RESPONSE; DRUG ISOLATION; DRUG MEGADOSE; HISTOPATHOLOGY; KIDNEY FUNCTION; KIDNEY INJURY; LIPID PEROXIDATION; LOW DRUG DOSE; MALE; MORINGA OLEIFERA; NEPHROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PLANT LEAF; RABBIT; RENAL PROTECTION; UREA BLOOD LEVEL;

ANIMALS; ANTI-BACTERIAL AGENTS; ANTIOXIDANTS; GENTAMICINS; KIDNEY; KIDNEY DISEASES; KIDNEY FUNCTION TESTS; LIPID PEROXIDATION; MALE; MORINGA OLEIFERA; OXIDATIVE STRESS; PLANT EXTRACTS; PLANT LEAVES; RABBITS;

MORINGA OLEIFERA; ORYCTOLAGUS CUNICULUS;

EID: 84872771180     PISSN: 09402993     EISSN: 16181433     Source Type: Journal    
DOI: 10.1016/j.etp.2011.11.006     Document Type: Article

References (37)

1. Afzal M., Khan N.A., Ghufran A., Iqbal A., Inamuddin M. Diuretic and nephroprotective effect of Jawarish Zarooni Sada - a polyherbal unani formulation. J Ethnopharmacol 2004, 91:219-223.
2. Ahmed M.B., Khater M.R. Evaluation of the protective potential of Ambrosia maritima extract on acetaminophen-induced liver damage. J Ethnopharmacol 2001, 75:169-174.
3. Ajith T.A., Aswathy M.S., Hema U. Protective effect of Zingiber officinale roscoe against anticancer drug doxorubicin-induced acute nephrotoxicity. Food Chem Toxicol 2008, 46:3178-3181.
4. Ali B.H. Gentamicin nephrotoxicity in humans and animals: some recent research. Gen Pharmacol 1995, 26:1477-1487.
5. Ali B.H., Ben Ismail T.H., Basheer A.A. Sex related differences in the susceptibility of rat to gentamicin nephrotoxicity: influence of gonadectomy and hormonal replacement therapy. Indian J Pharmacol 2001, 33:369-373.
6. Ashok Kumar N., Pari L. Antioxidant action of Moringa oleifera Lam. (drumstick) against antitubercular drugs induced lipid peroxidation in rats. J Med Food 2003, 6:255-259.
7. Atessahin A., Karahan I., Yilmaz S., çeribasi A.O., Princci I. The effect of manganese chloride on gentamicin-induced nephrotoxicity in rats. Pharmacol Res 2003, 48:637-642.
8. Babu R., Chaudhuri M. Homewater treatment by direct filtration with natural coagulant. J Water Health 2005, 3:27-30.
9. Baliga R., Ueda N., Walker P.D., Shah S.V. Oxidant mechanisms in toxic acute renal failure. Drug Metab Rev 1999, 31:971-997.
10. Balakumar P., Rohilla A., Thangathirupathi A. Gentamicin-induced nephrotoxicity: Do we have a promising therapeutic approach to blunt it?. Pharmacol Res 2010, 62:179-186.
11. Begg E.J., Barclay M.L. Aminoglycisides - 50 years on. Br J Clin Pharmacol 1995, 39:597-603.
12. Bonnet F. Effets néphroprotecteurs des glitazones. Med Maladies Metab 2007, 1:35-39.
13. Butler M.S. The role of natural product chemistry in drug discovery. J Nat Prod 2004, 67:2141-2153.
14. Esnault V. Slowing chronic renal failure progression: an update. Nephrol Ther 2007, 3:206-213.
15. Fatima S., Yusufi A.N.K., Mahmood R. Effect of cisplatin on renal brush border membrane enzymes and phosphate transport. Hum Exp Toxicol 2004, 23:547-554.
16. Hakimoglu F., Ki{dotless}zi{dotless}l G., Kanayb Z., Ki{dotless}zi{dotless}l M., Isi H. The effect of ethanol extract of Hypericum lysimachioides on lipid profile in hypercholesterolemic rabbits and its in vitro antioxidant activity. Atherosclerosis 2007, 192:113-122.
17. Halliwell B., Aeschbach R., Loliger J., Aruoma O.I. The characterization of antioxidants. Food Chem Toxicol 1995, 33:601-617.
18. Jaiswal D., Rai P.K., Kumar A., Mehta S., Watal G. Effect of Moringa oleifera Lam. leaves aqueous extract therapy on hyperglycemic rats. J Ethnopharmacol 2009, 123:392-396.
19. Kamal S. Nephroprotection of lacidipine against gentamycin-induced nephrotoxicity in albino rats. J Exp Pharmacol 2010, 2:59-63.
20. Karahan I., Atessahin A., Yi{dotless}lmaz S., Ceribasi A.O., Sakin F. Protective effect of lycopene on gentamicin-induced oxidative stress and nephrotoxicity in rats. Toxicology 2005, 215:198-204.
21. Lopaczynski W., Zeisel S.H. Antioxidants, programmed cell death, and cancer. Nutr Res 2001, 21:295-307.
22. Mahmood D.H. Waters, a comparative study of uranyl nitrate and cisplatin induced renal failure in rat. Eur J Drug Metab Pharmacol 1994, 19:327-336.
23. Martínez-Salgado C., López-Hernández F.J., López-Novoa J.M. Glomerular nephrotoxicity of aminoglycosides. Toxicol Appl Pharmacol 2007, 223:86-98.
24. Mingeot-Leclerq M.P., Tulkens P.M. Aminoglycosides: nephrotoxicity. Antimicrob Agents Chemother 1999, 43:1003-1012.
25. Naidu M.U., Shifow A.A., Kumar K.V., Ratnakar K.S. Ginkgo biloba extract ameliorates gentamicin-induced nephrotoxicity in rats. Phytomedicine 2000, 7:191-197.
26. Newman D.J., Cragg G.M., Snader K.M. Natural products as sources of new drugs over the period 1981-2002. J Nat Prod 2003, 66:1022-1037.
27. Ohkawa H., Onishi N., Yagi K. Assay for lipid peroxidation in animal tissue by thiobarbituric acid reaction. Anal Biochem 1979, 95:351-358.
28. Pari L., Ashok Kumar N. Hepatoprotective activity of Moringa oleifera on antitubercular drug-induced liver damage in rats. J Med Food 2002, 5:171-177.
29. Parlakpinar H., Tasdemir S., Polat A., Bay-Karabulut A., Vardi N., Ucar M., et al. Protective role of caffeic acid phenethyl ester (cape) on gentamicin-induced acute renal toxicity in rats. Toxicology 2005, 207:169-177.
30. Pedraza-Chaverri J., Gonzalez-Orozco A.E., Maldonado P.D., Barrera D., Medina-Campos O.N., Hernandez-Pando R. Diallyl disulfide ameliorates gentamicin-induced oxidative stress and nephropathy in rats. Eur J Pharmacol 2003, 473:71-78.
31. Priyamvada S., Priyadarshini M., Arivarasu N.A., Farooq N., Khan S., Khan S.A., et al. Studies on the protective effect of dietary fish oil on gentamicin-induced nephrotoxicity and oxidative damage in rat kidney. Prostaglandins Leukot Essent Fatty Acids 2008, 78:369-381.
32. Raju S., Kavimani S., Uma Maheshwara Rao V., Sreeramulu Reddy K., Vasanth Kumar G. Floral extract of Tecoma stans: a potent inhibitor of gentamicin-induced nephrotoxicity in vivo. Asian Pac J Trop Med 2011, 4:680-685.
33. Siddhuraju P., Becker K. Antioxidant properties of various solvent extracts of total phenolic constituents from three different agroclimatic origins of drumstick tree (Moringa oleifera Lam.) leaves. J Agric Food Chem 2003, 51:2144-2155.
34. Soliva C.R., Kreuzer, Foidl N., Foidl G., Machmuller A., Hess H.D. Feeding value of whole and extracted Moringa oleifera leaves for ruminants and their effects on ruminal fermentation in vitro. Anim Feed Sci Technol 2005, 118:47-62.
35. Tavafi M., Ahmadvand H. Effect of rosmarinic acid on inhibition of gentamicin induced nephrotoxicity in rats. Tissue Cell 2011, 43:392-397.
36. Verma A.R., Vijayakumar M., Mathela C.S., Rao C.V. In vitro and in vivo antioxidant properties of different fractions of Moringa oleifera leaves. Food Chem Toxicol 2009, 47:2196-2201.
37. Wongmekiat O., Leelarugrayub N., Thamprasert K. Beneficial effect of shallot (Allium ascalonicum L.) extract on cyclosporine nephrotoxicity in rats. Food Chem Toxicol 2008, 46:1844-1850.