Optimizing manufacture of liposomal berberine with evaluation of its antihepatoma effects in a murine xenograft model

International Journal of Pharmaceutics

Volumn 441, Issue 1-2, 2013, Pages 381-388

  Lin, Yung Chang ^a   Kuo, Jhan Yen ^a   Hsu, Chih Chieh ^a   Tsai, Wen Che ^a   Li, Wei Chu ^b   Yu, Ming Chiang ^a   Wen, Hsiao Wei ^a  

^a NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

^b CHINA MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Apoptosis; Caspase mitochondria dependent pathway; Human hepatic carcinoma; Liposomal berberine

Indexed keywords

BERBERINE; CASPASE; LIPID; LIPOSOME;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CELL VIABILITY; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG EFFICACY; DRUG ELIMINATION; DRUG MANUFACTURE; DRUG SYNTHESIS; DRUG TISSUE LEVEL; ENCAPSULATION; HUMAN; HUMAN CELL; HYDRATION; IC 50; IN VITRO STUDY; LIVER CELL CARCINOMA; MITOCHONDRION; MOUSE; NONHUMAN; PRIORITY JOURNAL; TUMOR VOLUME; TUMOR XENOGRAFT;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; BERBERINE; CARCINOMA, HEPATOCELLULAR; CASPASES; EXCIPIENTS; HEP G2 CELLS; HUMANS; INHIBITORY CONCENTRATION 50; LIPOSOMES; LIVER NEOPLASMS; MALE; MICE; MICE, NUDE; MITOCHONDRIA; POLYETHYLENE GLYCOLS; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84872760971     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2012.11.017     Document Type: Article

References (46)

1. A. Abuchowski, J.R. McCoy, N.C. Palczuk, T. van Es, and F.F. Davis Effect of covalent attachment of polyethylene glycol on immunogenicity and circulating life of bovine liver catalase J. Biol. Chem. 252 1977 3582 3586
2. T.M. Allen The use of glycolipids and hydrophilic polymers in avoiding rapid uptake of liposomes by the mononuclear phagocyte system Adv. Drug Deliv. Rev. 13 1994 285 309
3. N. Allon, A. Saxena, C. Chambers, and B.P. Doctor A new liposome-based gene delivery system targeting lung epithelial cells using endothelin antagonist J. Control. Release 160 2012 217 224
4. S.H. Bae, E.S. Jung, Y.M. Park, B.S. Kim, B.K. Kim, D.G. Kim, and W.S. Ryu Expression of cyclooxygenase-2 (COX-2) in hepatocellular carcinoma and growth inhibition of hepatoma cell lines by a COX-2 inhibitor, NS-398 Clin. Cancer Res. 7 2001 1410 1418
5. S. Bandak, D. Goren, A. Horowitz, D. Tzemach, and A. Gabizon Pharmacological studies of cisplatin encapsulated in long-circulating liposomes in mouse tumor models Anticancer Drugs 10 1999 911 920
6. G.R. Bartlett Phosphorus assay in column chromatography Journal of Biological Chemistry 234 1959 466 468
7. C.M. Chen, and H.C. Chang Determination of berberine in plasma, urine and bile by high-performance liquid chromatography J. Chromatogr. B. Biomed. Appl. 665 1995 117 123
8. S. Dadashzadeh, N. Mirahmadi, M.H. Babaei, and A.M. Vali Peritoneal retention of liposomes: Effects of lipid composition, PEG coating and liposome charge J. Control. Release 148 2010 177 186
9. Department of Health, Executive Yuan, Taiwan R.O.C. Statistics of causes of death (accessed August 29, 2012). Available at: http://www.doh.gov.tw/ CHT2006/DisplayStatisticFile.aspx?d=85451&s=1.
10. D.C. Drummond, O. Meter, K. Hong, D.B. Kirpotin, and D. Papahadjopoulos Optimizing liposomes for delivery of chemotherapeutic agents to solid tumors Pharmacol. Rev. 51 1999 691 743
11. B. Du, Y. Li, X.A.Y. Li, C. Chen, and Z. Zhang Preparation, characterization and in vivo evaluation of 2-methoxyestradiol-loaded liposomes Int. J. Pharm. 384 2010 140 147
12. Y. Feng, N. Wang, X. Ye, H. Li, Y. Feng, F. Cheung, and T. Nagamatsu Hepatoprotective effect and its possible mechanism of Coptidis rhizoma aqueous extract on carbon tetrachloride-induced chronic liver hepatotoxicity in rats J. Ethnopharmacol. 138 2011 683 690
13. K. Fukuda, Y. Hibiya, M. Muton, M. Koshiji, S. Akao, and H. Fujiwara Inhibition by berberine of cyclooxygenase-2 transcriptional activity in human colon cancer cells J. Ethnopharmacol. 66 1999 227 233
14. O. Garbuzenko, Y. Barenholz, and A. Priev Effect of grafted PEG on liposome size and on compressibility and packing of lipid bilayer Chem. Phys. Lipids 135 2005 117 129
15. C. Henninger, J. Huelsenbeck, S. Huelsenbeck, S. Grösch, A. Schad, K.J. Lackner, B. Kaina, and G. Fritz The lipid lowering drug lovastatin protects against doxorubicin-induced hepatotoxicity Toxicol. Appl. Pharmacol. 261 2012 66 73
16. H.J. Hinz, and J.M. Sturtevant Calorimetric studies of dilute aqueous suspensions of bilayers formed from synthetic l-α-lecithins J. Biol. Chem. 247 1972 6071 6075
17. Y.T. Ho, J.S. Yang, C.C. Lu, J.H. Chiang, T.C. Li, J.J. Lin, K.C. Lai, C.L. Liao, J.G. Lin, and J.G. Chung Berberine inhibits human tongue squamous carcinoma cancer tumor growth in a murine xenograft model Phytomedicine 16 2009 887 890
18. J.M. Hwang, H.C. Kuo, T.H. Tseng, J.Y. Liu, and C.Y. Chu Berberine induces apoptosis through a mitochondria/caspases pathway in human hepatoma cells Arch. Toxicol. 80 2006 62 73
19. T.J. Key, N.E. Allen, E.A. Spencer, and R.C. Travis The effect of diet on risk of cancer Lancet 360 2002 861 868
20. H. Koga, S. Sakisaka, M. Ohishi, T. Kawaguchi, E. Taniguchi, K. Sasatomi, M. Harada, T. Kusaba, M. Tanaka, R. Kimura, Y. Nakashima, O. Nakashima, M. Kojiro, T. Kurohiji, and M. Sata Expression of cyclooxygenase-2 in human hepatocellular carcinoma: relevance to tumor differentiation Hepatology 29 1999 688 696
21. C.L. Kuo, C.W. Chi, and T.Y. Liu The anti-inflammatory potential of berberine in vitro and in vivo Cancer Lett. 203 2004 127 137
22. B. Kwong, H. Liu, and D.J. Irvine Induction of potent anti-tumor responses while eliminating systemic side effects via liposome-anchored combinatorial immunotherapy Biomaterials 32 2011 5134 5147
23. C.C. Lin, L.T. Nq, F.F. Hsu, D.E. Shieh, and L.C. Chiang Cytotoxic effects of Coptic chinensis and Epimedium sagittatum extracts and their major constituents (berberine, coptisine and icariin) on hepatoma and leukaemia cell growth Clin. Exp. Pharmacol. Physiol. 31 2004 65 69
24. S.K. Mantena, S.D. Sharma, and S.K. Katiyar Berberine, a natural product, induces G1-phase cell cycle arrest and caspase-3-dependent apoptosis in human prostate carcinoma cells Mol. Cancer Ther. 5 2006 296 308
25. W.P. McGuire, W.J. Hoskins, M.F. Brady, P.R. Kucera, E.E. Partridge, K.Y. Look, D.L. Clarke-Pearson, and M. Davidson Cyclophosphamide and cisplatin compared with paclitaxel and cisplatin in patients with stage III and stage IV ovarian cancer N. Engl. J. Med. 334 1996 1 6
26. L.K. McLoon, and J. Wirtschafter Local injections of corticotropin releasing factor reduce doxorubicin-induced acute inflammation in the eyelid Invest. Ophthalmol. Vis. Sci. 38 1997 834 841
27. S.M. Meeran, S. Katiyar, and S.K. Katiyar Berberine-induced apoptosis in human prostate cancer cells is initiated by reactive oxygen species generation Toxicol. Appl. Pharm. 229 2008 33 43
28. J. Mönkkönen, J. Liukkonen, M. Taskinen, T.D. Heath, and A. Urtti Studies on liposome formulations for intra-articular delivery of clodronate J. Control. Release 35 1995 145 154
29. M.S. Newman, G.T. Colbern, P.K. Working, C. Engbers, and M.A. Amantea Comparative pharmacokinetics, tissue distribution, and therapeutic effectiveness of cisplatin encapsulated in long-circulating, pegylated liposomes (SPI-077) in tumor-bear mice Cancer Chemother. Pharmacol. 43 1999 1 7
30. M. Reers, T.W. Smith, and L.B. Chens J-aggregate formation of a carbocyanine as a quantitative fluorescent indicator of membrane potential Biochemistry 30 1991 4480 4486
31. H.A.H. Rongen, A. Bult, and W.P. van Bennekom Liposomes and immunoassays J. Immunol. Methods 204 1997 105 133
32. 6(3) or rhodamine 123, is a reliable fluorescent probe to assess delta psi changes in intact cells: implications for studies on mitochondrial functionality during apoptosis FEBS Lett. 411 1997 77 82
33. B. Schutte, R. Nuydens, H. Geerts, and F. Ramaekers Annexin V binding assay as a tool to measure apoptosis in differentiated neuronal cells J. Neurosci. Methods 86 1998 63 69
34. G. Sessa, and G. Weissmann Phospholipid spherules (liposomes) as a model for biological membranes J. Lipid Res. 9 1968 310 318
35. X. Sun, X. Zhang, H. Hu, Y. Lu, J. Chen, K. Yasuda, and H. Wang Berberine inhibits hepatic stellate cell proliferation and prevents experimental liver fibrosis Biol. Pharm. Bull. 32 2009 1533 1537
36. R. Suzuki, T. Takizawa, Y. Kuwata, M. Mutoh, N. Ishiguro, N. Utoguchi, A. Shinohara, M. Eriguchi, H. Yanagie, and K. Maruyama Effective anti-tumor activity of oxaliplatin encapsulated in transferring-PEG-liposome Int. J. Pharm. 346 2008 143 150
37. J. Tang, Y. Feng, S. Tsao, N. Wang, R. Curtaind, and Y. Wang Berberine and Coptidis Rhizoma as novel antineoplastic agents: A review of traditional use and biomedical investigations J. Ethnopharmacol. 126 2009 5 17
38. C.J. Thirupurasundari, R. Padmini, and S.N. Devaraj Effect of berberine on the antioxidant status, ultrastructural modifications and protein bound carbohydrates in azoxymethane-induced colon cancer in rats Chem. Biol. Interact. 177 2009 190 195
39. V. Torchilin, and V. Weissig Liposomes second ed. 2003 Oxford University Press New York
40. N.J. Tsagarakis, I. Drygiannakis, A.G. Batistakis, G. Kolios, and E.A. Kouroumalis A concentration-dependent effect of ursodeoxycholate on apoptosis and caspases activities of HepG2 hepatocellular carcinoma cells Eur. J. Pharmacol. 640 2010 1 7
41. P.L. Tsai, and T.H. Tsai Simultaneous determination of berberine in rat blood, liver and bile using microdialysis coupled to high-performance liquid chromatography J. Chromatogr. A 961 2002 125 130
42. K. Westesena, H. Bunjesa, and M.H.J. Kochb Physicochemical characterization of lipid nanoparticles and evaluation of their drug loading capacity and sustained release potential J. Control. Release 48 1997 223 236
43. F. Yang, T. Zhang, R. Zhang, and Y. Ito Application of analytical and preparative high-speed counter-current chromatography for separation of alkaloids from Coptis chinensis Franch. J. Chromatogr. A 829 1998 137 141
44. T. Yang, M.K. Choi, F.D. Cui, S.J. Kim, S.J. Chung, C.K. Shim, and D.D. Kim Preparation and evaluation of paclitaxel-loaded PEGylated immunoliposome J. Control. Release 120 2007 169 177
45. Y. Yoshizawa, Y. Kono, K.I. Ogawara, T. Kimura, and K. Higaki PEG liposomalization of paclitaxel improved its in vivo disposition and anti-tumor efficacy Int. J. Pharm. 412 2011 132 141
46. F. Yuan, M. Leunig, S.K. Huang, D.A. Berk, D. Papahadjopoulos, and R.K. Jain Microvascular permeability and interstitial penetration of sterically stabilized (stealth) liposomes in a human tumor xenograft Cancer Res. 54 1994 3352 3356