PEG liposomalization of paclitaxel improved its in vivo disposition and anti-tumor efficacy

International Journal of Pharmaceutics

Volumn 412, Issue 1-2, 2011, Pages 132-141

  Yoshizawa, Yuta ^a   Kono, Yusuke ^a   Ogawara, Ken Ichi ^a   Kimura, Toshikiro ^a   Higaki, Kazutaka ^a  

^a OKAYAMA UNIVERSITY   (Japan)

Author keywords

EPR effect; Paclitaxel; Passive targeting; PEG emulsion; PEG liposome

Indexed keywords

LIPOSOME; MACROGOL; PACLITAXEL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; DRUG BLOOD LEVEL; DRUG FORMULATION; DRUG RELEASE; EMULSION; IN VIVO STUDY; LIPOSOMAL DELIVERY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT; RETICULOENDOTHELIAL SYSTEM; SOLID TUMOR;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CARCINOMA; CELL LINE, TUMOR; CELL SURVIVAL; COLONIC NEOPLASMS; DRUG CARRIERS; DRUG COMPOUNDING; EMULSIONS; INHIBITORY CONCENTRATION 50; LIPOSOMES; MALE; MICE; MICE, INBRED BALB C; NANOSPHERES; PACLITAXEL; POLYETHYLENE GLYCOLS; RATS; RATS, WISTAR; SURVIVAL ANALYSIS; TISSUE DISTRIBUTION; TUMOR BURDEN;

EID: 79957473802     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2011.04.008     Document Type: Article

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