Characterizing the importance of the biotin carboxylase domain dimer for staphylococcus aureus pyruvate carboxylase catalysis

Biochemistry

Volumn 52, Issue 3, 2013, Pages 488-496

  Yu, Linda P C ^a   Chou, Chi Yuan ^b   Choi, Philip H ^a   Tong, Liang ^a  

^a Och Spine at New York Presbyterian Hospitals   (United States)

^b NATIONAL YANG MING UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE SITE; ANALYTICAL ULTRACENTRIFUGATION; BIOTIN CARBOXYLASE; CONFORMATIONAL CHANGE; DIMER INTERFACE; E. COLI; GEL FILTRATION; LONG-RANGE COMMUNICATIONS; MUTATION SITES; PYRUVATE CARBOXYLASE; SITE-SPECIFIC; STAPHYLOCOCCUS AUREUS; TETRAMERS;

BACTERIA; CARBON DIOXIDE; CARBOXYLATION; CATALYSIS; CATALYST ACTIVITY; CENTRIFUGATION; COENZYMES; ESCHERICHIA COLI; POLYPEPTIDES;

DIMERS;

CARBOXYLASE; DIMER; MONOMER; PYRUVATE CARBOXYLASE; TETRAMER;

ARTICLE; CATALYSIS; CHIMERA; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYSTAL STRUCTURE; CRYSTALLOGRAPHY; DIMERIZATION; ENZYME ACTIVITY; ENZYME SUBUNIT; GEL FILTRATION; GENE MUTATION; NONHUMAN; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN DOMAIN; STAPHYLOCOCCUS AUREUS; ULTRACENTRIFUGATION;

AMINO ACID SUBSTITUTION; BACTERIAL PROTEINS; BIOCATALYSIS; CARBON-NITROGEN LIGASES; CATALYTIC DOMAIN; CHROMATOGRAPHY, GEL; CRYSTALLOGRAPHY, X-RAY; HOLOENZYMES; KINETICS; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; MUTANT PROTEINS; PROTEIN CONFORMATION; PROTEIN MULTIMERIZATION; PROTEIN SUBUNITS; PYRUVATE CARBOXYLASE; RECOMBINANT FUSION PROTEINS; RECOMBINANT PROTEINS; STAPHYLOCOCCUS AUREUS; ULTRACENTRIFUGATION;

ESCHERICHIA COLI; STAPHYLOCOCCUS AUREUS;

EID: 84872760508     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi301294d     Document Type: Article

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