Site-directed mutagenesis of ATP binding residues of biotin carboxylase: Insight into the mechanism of catalysis

Journal of Biological Chemistry

Volumn 276, Issue 27, 2001, Pages 24991-24996

  Sloane, Valerie ^b   Blanchard, Carol Z ^b   Guillot, Frankie ^b   Waldrop, Grover L ^a  

^a LOUISIANA STATE UNIVERSITY   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINETRIPHOSPHATE; CARBOXYLATION; CATALYSIS; CRYSTAL STRUCTURE; ENZYMES; ESCHERICHIA COLI; FATTY ACIDS; MUTAGENESIS;

MUTANTS;

BIOCHEMISTRY;

ADENOSINE TRIPHOSPHATE; BIOTIN CARBOXYLASE; CARBOXYLASE; GLUTAMIC ACID; HISTIDINE; LYSINE; MUTANT PROTEIN; NUCLEOTIDE DERIVATIVE; UNCLASSIFIED DRUG; BICARBONATE; BIOTIN; LIGASE; MAGNESIUM;

ARTICLE; CARBOXYLATION; CATALYSIS; CHEMICAL REACTION KINETICS; CRYSTAL STRUCTURE; ENZYME SUBSTRATE COMPLEX; ESCHERICHIA COLI; KINETICS; MICHAELIS CONSTANT; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN STRUCTURE; SEQUENCE HOMOLOGY; SITE DIRECTED MUTAGENESIS; VELOCITY; WILD TYPE; AMINO ACID SUBSTITUTION; BIOSYNTHESIS; GENETICS; METABOLISM; PROTEIN CONFORMATION; X RAY CRYSTALLOGRAPHY;

ANIMALIA; ESCHERICHIA COLI; NEGIBACTERIA;

ADENOSINE TRIPHOSPHATE; AMINO ACID SUBSTITUTION; BICARBONATES; BIOTIN; CARBON-NITROGEN LIGASES; CATALYSIS; CRYSTALLOGRAPHY, X-RAY; ESCHERICHIA COLI; KINETICS; MAGNESIUM; MUTAGENESIS, SITE-DIRECTED; PROTEIN CONFORMATION;

EID: 0035816606     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M101472200     Document Type: Article

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