Crystal structure of the α6β6 holoenzyme of propionyl-coenzyme A carboxylase

Nature

Volumn 466, Issue 7309, 2010, Pages 1001-1005

  Huang, Christine S ^a   Sadre Bazzaz, Kianoush ^a   Shen, Yang ^a,d   Deng, Binbin ^b   Zhou, Z Hong ^b,c   Tong, Liang ^a  

^a Och Spine at New York Presbyterian Hospitals   (United States)

^b UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d ELI LILLY AND COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA6BETA6 HOLOENZYME; BIOTIN CARBOXYL CARRIER PROTEIN; BIOTIN CARBOXYLASE; CARBOXYLASE; CARBOXYLTRANSFERASE; CARRIER PROTEIN; HOLOENZYME; MONOMER; PROPIONYL COENZYME A CARBOXYLASE; UNCLASSIFIED DRUG; ACETYL COENZYME A CARBOXYLASE; BIOTIN; FATTY ACID SYNTHASE; LIGASE; METHYLMALONYL COENZYME A DECARBOXYLASE; PROTEIN BINDING; PROTEIN SUBUNIT;

ABNORMALITY; AMINO ACID; CATABOLISM; CRYSTAL STRUCTURE; ELECTRON MICROSCOPY; ENZYME ACTIVITY; FATTY ACID; MUTATION; PUBLIC HEALTH; RECONSTRUCTION;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BACTERIUM; CARBOXYLATION; CATALYSIS; CRYOELECTRON MICROSCOPY; CRYSTAL STRUCTURE; CYTOARCHITECTURE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME MODIFICATION; ENZYME REACTIVATION; ENZYME STRUCTURE; ENZYME SUBUNIT; IMAGE RECONSTRUCTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; BIOCATALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; ENZYMOLOGY; GENETICS; HUMAN; METABOLISM; MUTATION; PROPIONIC ACIDEMIA; PROTEIN QUATERNARY STRUCTURE; PROTEIN SUBUNIT; PROTEIN TERTIARY STRUCTURE; RHODOBACTERACEAE; STRUCTURE ACTIVITY RELATION; ULTRASTRUCTURE; X RAY CRYSTALLOGRAPHY;

ACETYL-COA CARBOXYLASE; BIOCATALYSIS; BIOTIN; CARBON-NITROGEN LIGASES; CARRIER PROTEINS; CATALYTIC DOMAIN; CRYOELECTRON MICROSCOPY; CRYSTALLOGRAPHY, X-RAY; HOLOENZYMES; HUMANS; METHYLMALONYL-COA DECARBOXYLASE; MODELS, MOLECULAR; MUTATION; PROPIONIC ACIDEMIA; PROTEIN BINDING; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, TERTIARY; PROTEIN SUBUNITS; RHODOBACTERACEAE; STRUCTURE-ACTIVITY RELATIONSHIP; FATTY ACID SYNTHASE, TYPE II;

BACTERIA (MICROORGANISMS); EUKARYOTA;

EID: 77955874035     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature09302     Document Type: Article

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