Fast interpretation of thromboelastometry in non-cardiac surgery: Reliability in patients with hypo-, normo-, and hypercoagulability

British Journal of Anaesthesia

Volumn 110, Issue 2, 2013, Pages 222-230

  Gorlinger K ^a   Dirkmann, D ^a   Solomon, C ^b   Hanke, A A ^c  

^a UNIVERSITY OF DUISBURG ESSEN   (Germany)

^b PARACELSUS MEDICAL UNIVERSITY   (Austria)

^c HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

blood coagulation; liver transplantation; measurement techniques; postpartum haemorrhage; thromboelastometry; trauma

Indexed keywords

AREA UNDER THE CURVE; ARTICLE; BLOOD CLOTTING; BLOOD CLOTTING TIME; BLOOD EXAMINATION; CORRELATION COEFFICIENT; HUMAN; HYPERCOAGULABILITY; HYPOCOAGULABILITY; PREDICTION; PRIORITY JOURNAL; RECEIVER OPERATING CHARACTERISTIC; RELIABILITY; RETROSPECTIVE STUDY; SENSITIVITY AND SPECIFICITY; STATISTICAL SIGNIFICANCE; THROMBOELASTOMETRY;

EID: 84872732533     PISSN: 00070912     EISSN: 14716771     Source Type: Journal    
DOI: 10.1093/bja/aes374     Document Type: Article

References (50)

1. Toulon P, Ozier Y, Ankri A, Flé ron MH, Leroux G, Samama CM. Point-of-Care versus central laboratory coagulation testing during haemorrhagic surgery A multicenter study. Thromb Haemost 2009; 101: 394-401
2. Davenport R, Manson J, De'Ath H, et al. Functional definition and characterization of acute traumatic coagulopathy. Crit Care Med 2011; 39: 2652-8
3. Haas T, Spielmann N, Mauch J, et al. Comparison of thromboelastometry (ROTEMw) with standard plasmatic coagulation testing in paediatric surgery. Br J Anaesth 2012; 108: 36-41
4. Johansson PI. Coagulation monitoring of the bleeding traumatized patient. Curr Opin Anaesthesiol 2012; 25: 235-41
5. Murad MH, Stubbs JR, Gandhi MJ, et al. The effect of plasma transfusion on morbidity and mortality: A systematic review and meta-Analysis. Transfusion 2010; 50: 1370-83
6. Ho AM, Dion PW, Yeung JH, et al. Prevalence of survivor bias in observational studies on fresh frozen plasma:erythrocyte ratios in trauma requiring massive transfusion. Anesthesiology 2012; 116: 716-28
7. Wafaisade A, Lefering R, Maegele M, et al. Coagulation management of bleeding trauma patients is changing in German trauma centers: An analysis from the trauma registry of the German Society for Trauma Surgery. J Trauma Acute Care Surg 2012; 72: 936-42
8. Watson GA, Sperry JL, Rosengart MR, et al. Fresh frozen plasma is independently associated with a higher risk of multiple organ failure and acute respiratory distress syndrome. J Trauma 2009; 67: 221-30
9. Johnson JL, Moore EE, Kashuk JL, et al. Effect of blood products transfusion on the development of postinjury multiple organ failure. Arch Surg 2010; 145: 973-7
10. Inaba K, Branco BC, Rhee P, et al. Impact of plasma transfusion in trauma patients who do not require massive transfusion. J Am Coll Surg 2010; 210: 957-65
11. Borgman MA, Spinella PC, Holcomb JB, et al. The effect of FFP:RBC ratio on morbidity and mortality in trauma patients based on transfusion prediction score. Vox Sang 2011; 101: 44-54
12. Stanworth SJ, Grant-Casey J, Lowe D, et al. The use of freshfrozen plasma in England: High levels of inappropriate use in adults and children. Transfusion 2011; 51: 62-70
13. Rugeri L, Levrat A, David JS, et al. Diagnosis of early coagulation abnormalities in trauma patients by rotation thrombelastography. J Thromb Haemost 2007; 5: 289-95 (Pubitemid 46139453)
14. Goerlinger K, Dirkmann D, Hanke A, Dusse F, Hartmann M. ROTEMbased algorithm for point-of-Care coagulation management in visceral surgery and liver transplantation: Experience of eight years and 829 LTX. Liver Transplant 2008; 14(Suppl. 1): S203-4
15. Huissoud C, Carrabin N, Audibert F, et al. Bedside assessment of fibrinogen level in postpartum haemorrhage by thrombelastometry. BJOG 2009; 116: 1097-102
16. Roullet S, Pillot J, Freyburger G, et al. Rotation thromboelastometry detects thrombocytopenia and hypofibrinogenaemia during orthotopic liver transplantation. Br J Anaesth 2010; 104: 422-8
17. Schöchl H, Cotton B, Inaba K, et al. FIBTEM provides early prediction of massive transfusion in trauma. Crit Care 2011; 15: R265
18. Blasi A, Beltran J, Pereira A, et al. An assessment of thromboelastometry to monitor blood coagulation and guide transfusion support in liver transplantation. Transfusion 2012, doi: 10.1111/j.1537-2995.2011.03526.x. [Epub ahead of print
19. Haas T, Spielmann N, Mauch J, Speer O, Schmugge M, Weiss M. Reproducibility of thrombelastometry (ROTEMw): Point-of-Care versus hospital laboratory performance. Scand J Clin Lab Invest 2012; 72: 313-7
20. Görlinger K, Dirkmann D, Müller-Beißenhirtz H, Paul A, Hartmann M, Saner F. Thromboelastometry-based perioperative coagulation management in visceral surgery and liver transplantation: Experience of 10 years and 1105 LTX. Liver Transplant 2010; 16(Suppl. 1): S86
21. Spahn DR, Ganter MT. Towards early individual goal-directed coagulation management in trauma patients. Br J Anaesth 2010; 105: 103-5
22. Ganter MT, Spahn DR. Active, personalized, and balanced coagulation management saves lives in patients with massive bleeding. Anesthesiology 2010; 113: 1016-8
23. Schöchl H, Nienaber U, Hofer G, et al. Goal-directed coagulation management of major trauma patients using thromboelastometry (ROTEM)-Guided administration of fibrinogen concentrate and prothrombin complex concentrate. Crit Care 2010; 14: R55
24. Schöchl H, Nienaber U, Maegele M, et al. Transfusion in trauma: Thromboelastometry-Guided coagulation factor concentratebased therapy versus standard fresh frozen plasma-based therapy. Crit Care 2011; 15: R83
25. Nienaber U, Innerhofer P, Westermann I, et al. The impact of fresh frozen plasma vs coagulation factor concentrates on morbidity and mortality in trauma-Associated haemorrhage and massive transfusion. Injury 2011; 42: 697-701
26. Görlinger K, Dirkmann D, Weber CF, Rahe-Meyer N, Hanke AA. Algorithms for transfusion and coagulation management in massive haemorrhage. Anästh Intensivmed 2011; 52: 145-59
27. Görlinger K, Dirkmann D, Hanke AA, et al. First-line therapy with coagulation factor concentrates combined with point-of-Care coagulation testing is associated with decreased allogeneic blood transfusion in cardiovascular surgery: A retrospective, single-Center cohort study. Anesthesiology 2011; 115: 1179-91
28. Schöchl H, Maegele M, Solomon C, Görlinger K, Voelckel W. Early and individualized goal-directed therapy for trauma-induced coagulopathy. Scand J Trauma Resusc Emerg Med 2012; 20: 15
29. Görlinger K, Fries D, Dirkmann D, Weber CF, Hanke AA, Schöchl H. Reduction of fresh frozen plasma requirements by perioperative point-of-Care coagulation management with early calculated goal-directed therapy. Transfus Med Hemother 2012; 39: 104-13
30. Weber CF, Görlinger K, Meininger D, et al. Point-of-Care testing: A prospective randomized clinical trial of efficacy in coagulopathic cardiac surgery patients. Anesthesiology 2012; 117: 531-47
31. Görlinger K, Jambor C, Hanke AA, et al. Perioperative coagulation management and control of platelet transfusion by point-of-Care platelet function analysis. Transfus Med Hemother 2007; 34: 396-411 (Pubitemid 350249146)
32. Lang T, Bauters A, Braun SL, et al. Multi-Centre investigation on reference ranges for ROTEM thromboelastometry. Blood Coagul Fibrinolysis 2005; 16: 301-10 (Pubitemid 40705054)
33. Bland JM, Altman DG. Statistical methods for assessing agreement between two methods of clinical measurement. Lancet 1986; 8476: 307-10 (Pubitemid 16134762)
34. Bland JM, Altman DG. Agreed statistics: Measurement method comparison. Anesthesiology 2012; 116: 182-5
35. Lasko TA, Bhagwat JG, Zou KH, Ohno-Machado L. The use of receiver operating characteristic curves in biomedical informatics. J Biomed Inform 2005; 38: 404-15 (Pubitemid 41405811)
36. Zou KH, O'Malley AJ, Mauri L. Receiver-operating characteristic analysis for evaluating diagnostic tests and predictive models. Circulation 2007; 115: 654-7 (Pubitemid 46226175)
37. Hilden J. The area under the ROC curve and its competitors. Med Decis Making 1991; 11: 95-101
38. Katori N, Tanaka KA, Szlam F, Levy JH. The effects of platelet count on clot retraction and tissue plasminogen activatorinduced fibrinolysis on thrombelastography. Anesth Analg 2005; 100: 1781-5 (Pubitemid 40712739)
39. Herbstreit F, Winter EM, Peters J, Hartmann M. Monitoring of haemostasis in liver transplantation: Comparison of laboratory based and point of care tests. Anaesthesia 2010; 65: 44-9
40. Charbit B, Mandelbrot L, Samain E, et al. The decrease of fibrinogen is an early predictor of the severity of postpartum hemorrhage. J Thromb Haemost 2007; 5: 266-73 (Pubitemid 46139450)
41. Karlsson M, Ternström L, Hyllner M, Baghaei F, Nilsson S, Jeppsson A. Plasma fibrinogen level, bleeding, and transfusion after on-Pump coronary artery bypass grafting surgery: A prospective observational study. Transfusion 2008; 10: 2152-8
42. Reinhöfer M, Brauer M, Franke U, Bar D, Marx G, Lösche W. The value of rotation thromboelastometry to monitor disturbed perioperative haemostasis and bleeding risk in patients with cardiopulmonary bypass. Blood Coagul Fibrinolysis 2008; 19: 212-9 (Pubitemid 351498725)
43. Carling MS, Jeppsson A, Wessberg P, Henriksson A, Baghaei F, Brisby H. Preoperative fibrinogen plasma concentration is associated with perioperative bleeding and transfusion requirements in scoliosis surgery. Spine 2011; 36: 549-55
44. Fenger-Eriksen C, Jensen TM, Kristensen BS, et al. Fibrinogen substitution improves whole blood clot firmness after dilution with hydroxyethyl starch in bleeding patients undergoing radical cystectomy: A randomized, placebo-Controlled clinical trial. J Thromb Haemost 2009; 7: 795-802
45. Bolliger D, Görlinger K, Tanaka KA. Pathophysiology and treatment of coagulopathy in massive hemorrhage and hemodilution. Anesthesiology 2010; 113: 1205-19
46. Fenger-Eriksen C, Moore GW, Rangarajan S, Ingerslev J, Sørensen B. Fibrinogen estimates are influenced by methods of measurement and hemodilution with colloid plasma expanders. Transfusion 2010; 50: 2571-6
47. Spiezia L, Radu C, Marchioro P, et al. Peculiar whole blood rotation thromboelastometry (Rotem) profile in 40 sideropenic anaemia patients. Thromb Haemostat 2008; 100: 1106-10
48. Ogawa S, Szlam F, Bolliger D, Nishimura T, Chen EP, Tanaka KA. The impact of hematocrit on fibrin clot formation assessed by rotational thromboelastometry. Anesth Analg 2012; 115: 16-21
49. Solomon C, Rahe-Meyer N, Schöchl H, Ranucci M, Görlinger K. Effect of haematocrit on fibrin-based clot firmness in the FIBTEM assay. Blood Transfus 2012; 10, accepted for publication
50. Coakley M, Reddy K, Mackie I, Mallett S. Transfusion triggers in orthotopic liver transplantation: A comparison of the thromboelastometry analyzer, the thromboelastogram, and conventional coagulation tests. J Cardiothorac Vasc Anesth 2006; 20: 548-53 (Pubitemid 44119274)