Tezosentan increases nitric oxide signaling via enhanced hydrogen peroxide generation in lambs with surgically induced acute increases in pulmonary blood flow

Journal of Cellular Biochemistry

Volumn 114, Issue 2, 2013, Pages 435-447

  Kumar, Sanjiv ^a   Oishi, Peter E ^b,c   Rafikov, Ruslan ^a   Aggarwal, Saurabh ^a   Hou, Yali ^a   Datar, Sanjeev A ^b   Sharma, Shruti ^a   Azakie, Anthony ^b   Fineman, Jeffrey R ^b,c   Black, Stephen M ^a  

^a MEDICAL COLLEGE OF GEORGIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Biomechanical forces; Catalase; Endothelin 1; ENOS; Hydrogen peroxide; Nitric oxide; Pulmonary blood flow

Indexed keywords

CATALASE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; ENDOTHELIN 1; ENDOTHELIN RECEPTOR; HYDROGEN PEROXIDE; NITRIC OXIDE; SERINE; TEZOSENTAN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOAVAILABILITY; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; LAMB; LUNG BLOOD FLOW; LUNG PARENCHYMA; LUNG VASOCONSTRICTION; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PULMONARY ARTERY; SHEAR STRESS; SIGNAL TRANSDUCTION;

ANIMALS; CATALASE; ENDOTHELIAL CELLS; ENDOTHELIN-1; HEMODYNAMICS; HYDROGEN PEROXIDE; LUNG; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE III; PHOSPHORYLATION; PULMONARY ARTERY; PYRIDINES; RECEPTOR, ENDOTHELIN A; REGIONAL BLOOD FLOW; SHEEP, DOMESTIC; SIGNAL TRANSDUCTION; TETRAZOLES;

OVIS ARIES;

EID: 84872727361     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.24383     Document Type: Article

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