Epidermal growth factor promotes protein degradation of epithelial protein lost in neoplasm (EPLIN), a putative metastasis suppressor, during epithelial-mesenchymal transition

Journal of Biological Chemistry

Volumn 288, Issue 3, 2013, Pages 1469-1479

  Zhang, Shumin ^a   Wang, Xu ^a   Iqbal, Shareen ^a   Wang, Yanru ^a   Osunkoya, Adeboye O ^a   Chen, Zhengjia ^b   Chen, Zhuo ^a   Shin, Dong M ^a   Yuan, Hongwei ^c   Wang, Yongqiang A ^d   Zhau, Haiyen E ^e   Chung, Leland W K ^e   Ritenour, Chad ^a   Kucuk, Omer ^a   Wu, Daqing ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b EMORY UNIVERSITY   (United States)

^c INNER MONGOLIA MEDICAL COLLEGE   (China)

^d OCEAN NANOTECH LLC   (United States)

^e CEDARS SINAI MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTORS; EPITHELIAL-MESENCHYMAL TRANSITION; EXPERIMENTAL MODELS; EXTRACELLULAR- SIGNAL-REGULATED KINASE 1/2; INVASIVENESS; MECHANISTIC STUDIES; MOLECULAR MECHANISM; PHARMACOLOGICAL INHIBITION; PHOSPHORYLATION SITES; POINT MUTATIONS; PROMOTING PROTEIN; PROSTATE CANCERS; PROTEIN DEGRADATION; SERINE RESIDUES; SIGNALING CASCADES; TUMOR METASTASIS; UBIQUITINATION;

AMINO ACIDS; DISEASES; PHOSPHORYLATION; PROTEINS; SIGNALING; TUMORS;

PATHOLOGY;

EPIDERMAL GROWTH FACTOR; EPITHELIAL MARKER LOST IN NEOPLASM; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; RECOMBINANT EPIDERMAL GROWTH FACTOR; SERINE; TUMOR MARKER; UNCLASSIFIED DRUG; UVOMORULIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER INVASION; CANCER STAGING; CARCINOGENESIS; CONTROLLED STUDY; EPITHELIAL MESENCHYMAL TRANSITION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; MALE; METASTASIS INHIBITION; MOUSE; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN METABOLISM; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; TUMOR XENOGRAFT; UBIQUITINATION;

CELL LINE, TUMOR; CELL MOVEMENT; CYTOSKELETAL PROTEINS; EPIDERMAL GROWTH FACTOR; EPITHELIAL-MESENCHYMAL TRANSITION; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, REPORTER; HUMANS; MALE; NEOPLASM METASTASIS; NEOPLASM PROTEINS; PROSTATIC NEOPLASMS; PROTEOLYSIS; SIGNAL TRANSDUCTION; TRANSFECTION;

EID: 84872715614     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.438341     Document Type: Article

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