Granzyme B-mediated damage of CD8+ T Cells Impairs graft-versus-tumor effect

Journal of Immunology

Volumn 190, Issue 3, 2013, Pages 1341-1350

  Bian, Guanglin ^a   Ding, Xilai ^a   Leigh, Nicholas D ^a   Tang, Youzhou ^a   Capitano, Maegan L ^a   Qiu, Jingxin ^a   McCarthy, Philip L ^a   Liu, Hong ^a   Cao, Xuefang ^a  

^a ROSWELL PARK CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FAS LIGAND; GAMMA INTERFERON; GRANZYME B;

ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER CONTROL; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL DEATH; ENZYME ACTIVATION; ENZYME DEFICIENCY; GRAFT VERSUS LEUKEMIA EFFECT; HISTOPATHOLOGY; IMMUNOCOMPETENT CELL; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; T CELL DEPLETION; TUMOR CELL; WILD TYPE;

ANIMALS; APOPTOSIS; BONE MARROW TRANSPLANTATION; CD8-POSITIVE T-LYMPHOCYTES; CELL DIVISION; CELL LINE, TUMOR; FAS LIGAND PROTEIN; GRAFT VS HOST DISEASE; GRAFT VS TUMOR EFFECT; GRANZYMES; IMMUNOLOGIC MEMORY; INTERFERON-GAMMA; LYMPHOCYTE ACTIVATION; LYMPHOMA; MICE; MICE, INBRED STRAINS; RADIATION CHIMERA; TUMOR BURDEN;

EID: 84872702952     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1201554     Document Type: Article

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