New insights into the brain involvement in patients with Crohn's disease: A voxel-based morphometry study

Neurogastroenterology and Motility

Volumn 25, Issue 2, 2013, Pages

  Agostini, A ^a,b   Benuzzi, F ^c   Filippini, N ^d,e,f   Bertani, A ^g   Scarcelli, A ^g   Farinelli, V ^c   Marchetta, C ^b   Calabrese, C ^b   Rizzello, F ^b   Gionchetti, P ^b   Ercolani, M ^a   Campieri, M ^b   Nichelli, P ^c  

^a UNIVERSITY OF BOLOGNA   (Italy)

^b UNIVERSITY OF BOLOGNA   (Italy)

^c UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

^d UNIVERSITY OF OXFORD   (United Kingdom)

^e UNIVERSITY OF OXFORD   (United Kingdom)

^f IRCCS ISTITUTO CENTRO SAN GIOVANNI DI DIO FATEBENEFRATELLI   (Italy)

^g UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

Author keywords

Brain neuroplastic changes; Cingulate cortex; Crohn's disease; Frontal lobe; Pain matrix; Voxel based morphometry

Indexed keywords

BIOLOGICAL PRODUCT;

ABDOMINAL PAIN; ADULT; ARTICLE; BRAIN; BRAIN DISEASE; BRAIN REGION; BRAIN SIZE; CLINICAL ARTICLE; COGNITION; CONTROLLED STUDY; CROHN DISEASE; DIAGNOSTIC TEST ACCURACY STUDY; DISEASE ASSOCIATION; DISEASE DURATION; FEMALE; FRONTAL CORTEX; GRAY MATTER; HUMAN; ILEUM RESECTION; LIMBIC CORTEX; MALE; NEOCORTEX; NEUROIMAGING; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; REMISSION; SENSITIVITY AND SPECIFICITY; VOXEL BASED MORPHOMETRY;

ADULT; BRAIN; CROHN DISEASE; FEMALE; HUMANS; IMAGE INTERPRETATION, COMPUTER-ASSISTED; MAGNETIC RESONANCE IMAGING; MALE;

EID: 84872686347     PISSN: 13501925     EISSN: 13652982     Source Type: Journal    
DOI: 10.1111/nmo.12017     Document Type: Article

References (45)

1. Pizzi LT, Weston CM, Goldfarb L et al. Impact of chronic conditions on quality of life in patients with inflammatory bowel disease. Inflamm Bowel Dis 2006; 12: 47-52.
2. Agostini A, Filippini N, Benuzzi F et al. Functional magnetic resonance imaging study reveals differences in the habituation to psychological stress in patients with Crohn's disease versus healthy controls. J Behav Med 2012; doi: 10.1007/s10865-012-9441-1.
3. Agostini A, Rizzello F, Ravegnani G et al. Parental bonding and inflammatory bowel disease. Psychosomatics 2010; 51: 14-21.
4. Agostini A, Rizzello F, Ravegnani G et al. Adult attachment and early parental experiences in patients with Crohn's disease. Psychosomatics 2010; 51: 208-15.
5. Agostini A, Filippini N, Cevolani D et al. Brain functional changes in patients with Ulcerative Colitis: an fMRI study on emotional processing. Inflamm Bowel Dis 2011; 17: 1769-77.
6. Dancey PD, Attree EA, Stuart G et al. Words fail me: the verbal IQ deficit in inflammatory bowel disease and irritable bowel syndrome. Inflamm Bowel Dis 2009; 15: 852-7.
7. Bielefeldt K, Davis B, Binion DG. Pain and inflammatory bowel disease. Inflamm Bowel Dis 2009; 15: 778-98.
8. Kuchinad A, Schweinhardt P, Seminowicz DA et al. Accelerated brain gray matter loss in fibromyalgia patients: premature aging of the brain? J Neurosci 2007; 27: 4004-7.
9. Apkarian AV, Sosa Y, Sonty S et al. Chronic back pain is associated with decreased prefrontal and thalamic gray matter density. J Neurosci 2004; 24: 10410-5.
10. Schmidt-Wilcke T, Leinisch E, Straube A et al. Gray matter decrease in patients with chronic tension type headache. Neurology 2005; 65: 1483-6.
11. Blankstein U, Chen J, Diamant NE et al. Altered brain structure in irritable bowel syndrome: potential contributions of pre-existing and disease-driven factors. Gastroenterology 2010; 138: 1783-9.
12. Seminowicz DA, Labus JS, Bueller JA et al. Regional gray matter density changes in brains of patients with irritable bowel syndrome. Gastroenterology 2010; 139: 48-57.
13. Elsenbruch S, Rosenberger C, Bingel U et al. Patients with irritable bowel syndrome have altered emotional modulation of neural responses to visceral stimuli. Gastroenterology 2010; 139: 1310-9.
14. Porro CA, Lui F, Facchin P et al. Percept-related activity in the human somatosensory system: functional magnetic resonance imaging studies. Magn Reson Imaging 2004; 22: 1539-48.
15. Treede R, Kenshalo D, Gracely R et al. The cortical representation of pain. Pain 1999; 79: 105-11.
16. Harrison NA, Brydon L, Walker C et al. Neural origins of human sickness in interoceptive responses to inflammation. Biol Psychiatry 2009; 66: 415-22.
17. Quan N, Banks WA. Brain-immune communication pathways. Brain behaviour and immunity 2007; 21: 727-35.
18. Konsman JP, Kelley K, Dantzer R. Temporal and spatial relationships between lipopolysaccharide-induced expression of Fos, interleukin-1beta and inducible nitric oxide synthesis in rat brain. Neuroscience 1999; 89: 535-48.
19. Dantzer R, O'Connor JC, Freund GG et al. From inflammation to sickness and depression: when the immune system subjugates the brain. Nat Rev Neurosci 2008; 9: 46-56.
20. Jones MP, Dilley JB, Drossmann D. Brain-gut connections in functional GI disorders: anatomic and physiologic relationships. Neurogastroenterol Motil 2006; 18: 91-103.
21. Ashburner J, Friston KJ. Voxel-based morphometry-the methods. Neuroimage 2000; 11: 805-21.
22. Oldfield RC. The assessment and analysis of handedness: the Edinburgh Inventory. Neuropsychologia 1971; 9: 97-113.
23. Brown ES, Woolston DJ, Frol AB. Amygdala volume in patients receiving chronic corticosteroid therapy. Biol Psychiatry 2008; 63: 705-9.
24. Younger JW, Chu LF, D'Arcy NT et al. Prescription opioid analgesics rapidly changes the human brain. Pain 2011; 152: 1803-10.
25. Best WR, Becktel JM, Singleton JW et al. Development of a Crohn's disease activity index. National Cooperative Crohn's Disease Study. Gastroenterology 1976; 70: 439-44.
26. Satsangi J, Silverberg MS, Vermeire S, Colombel JF. The Montreal classification of inflammatory bowel disease: controversies, consensus, and implications. Gut 2006; 55: 749-53.
27. Vogt BA. Pain and emotion interactions in subregions of the cingulate gyrus. Nat Rev Neurosci 2005; 6: 533-44.
28. Palomero-Gallagher N, Vogt BA, Schleicher A et al. Receptor architecture of human cingulate cortex: evaluation of the four-region neurobiological model. Hum Brain Mapp 2009; 30: 2336-55.
29. Vogt BA, Vogt L. Cytology of human dorsal midcingulate and supplementary motor cortices. J Chem Neuroanat 2003; 26: 301-9.
30. Good CD, Johnsrude IS, Ashburner J et al. A voxel-based morphometric study of ageing in 465 normal adult human brains. Neuroimage 2001; 14: 21-36.
31. Chetelat G, Landeau B, Eustache F et al. Using voxel-based morphometry to map the structural changes associated with rapid conversion in MCI: a longitudinal MRI study. Neuroimage 2005; 27: 934-46.
32. Chetelat G, Fouquet M, Kalpouzos G et al. Three-dimensional surface mapping of hippocampal atrophy progression from MCI to AD and over normal aging as assessed using voxel-based morphometry. Neuropsychologia 2008; 46: 1721-31.
33. Matsumoto R, Ito H, Takahashi H, Ando T et al. Reduced gray matter volume of dorsal cingulate cortex in patients with obsessive-compulsive disorder: a voxel-based morphometric study. Psychiatry Clin Neurosci 2010; 64: 541-7.
34. Santana MT, Jackowski AP, da Silva HH et al. Auras and clinical features in temporal lobe epilepsy: a new approach on the basis of voxel-based morphometry. Epilepsy Res 2010; 89: 327-38.
35. Mevel K, Desgranges B, Baron JC et al. Which SPM Method Should Be Used to Extract Hippocampal Measures in Early Alzheimer's Disease? J Neuroimaging 2011; 21: 310-6.
36. Tzourio-Mazoyer N, Landeau B, Papathanassiou D et al. Automated anatomical labelling of activations in spm using a macroscopic anatomical parcellation of the MNI MRI single subject brain. Neuroimage 2002; 15: 273-89.
37. Brett M, Anton J, Valabregue R et al. Region of interest analysis using an SPM toolbox [abstract]. Presented at the 8th International Conference on Functional Mapping of the Human Brain, June 2-6, 2002, Sendai, Japan. Available on CD-ROM in Neuroimage, Vol 16.
38. Schweinhardt P, Kuchinad A, Pukall CF et al. Increased gray matter density in young women with chronic vulvar pain. Pain 2008; 140: 411-9.
39. May A. Chronic pain may change the structure of the brain. Pain 2008; 137: 7-15.
40. Mayer EA, Tillisch K. The brain-gut axis in abdominal pain syndromes. Annu Rev Med 2011; 62: 381-96.
41. Wall P, Melzack R. Textbook of Pain, 4th edn. Edingburgh, London, Madrid: Churchill Livingstone, 1999.
42. Akbar A, Yiangou Y, Facer P et al. Expression of the TRPV1 receptor differs in quiescent inflammatory bowel disease with or without abdominal pain. Gut 2010; 59: 767-74.
43. Miller AH, Maletic V, Raison CL. Inflammation and its discontents: the role of cytokines in the pathophysiology of major depression. Biol Psychiatry 2009; 65: 732-41.
44. Buntinx M, Moreels M, Vandenabeele F et al. Cytokine-induced cell death in human oligodendroglial cell lines: I. Synergistic effects of IFN-gamma and TNF-alpha on apoptosis. J Neurosci Res 2004; 76: 834-45.
45. Dantzer R, Konsman JD, Bluthe RM et al. Neural and humoral pathways of communication from the immune system to the brain: Parallel or convergent? Auton Neurosci Basic Clin 2000; 85: 60-5.