Tissue modification of the lateral compartment of the tibio-femoral joint following in vivo varus loading in the rat

Journal of Biomechanical Engineering

Volumn 134, Issue 10, 2012, Pages 1-6

  Roemhildt, M L ^a,b   Beynnon, B D ^a   Gardner Morse, M ^a   Anderson, K ^a   Badger, G J ^a  

^a UNIVERSITY OF VERMONT COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF VERMONT   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL; ARTICLE; BIOMECHANICS; CARTILAGE; CYTOLOGY; FEMUR; HINDLIMB; INSTRUMENTATION; JOINT; MALE; MATERIALS TESTING; MECHANICS; PHYSIOLOGY; PILOT STUDY; RAT; SPRAGUE DAWLEY RAT; TIBIA; TIME;

ANIMALS; BIOMECHANICS; CARTILAGE; FEMUR; HINDLIMB; JOINTS; MALE; MATERIALS TESTING; MECHANICAL PROCESSES; PILOT PROJECTS; RATS; RATS, SPRAGUE-DAWLEY; TIBIA; TIME FACTORS;

EID: 84872671970     PISSN: 01480731     EISSN: 15288951     Source Type: Journal    
DOI: 10.1115/1.4007453     Document Type: Article

References (26)

1. Brouwer, G. M., Tol, A. W. V., Bergink, A. P., Belo, J. N., Bernsen, R. M. D., Reijman, M., Pols, H. A. P., and Bierma-Zeinstra, S. M. A., 2007, “Association Between Valgus and Varus Alignment and the Development and Progression of Radiographic Osteoarthritis of the Knee,” Arthritis Rheum., 56(4), pp. 1204-1211.
2. Felson, D. T., Anderson, J. J., Naimark, A., Walker, A. M., and Meenan, R. F., 1988, “Obesity and Knee Osteoarthritis. The Framingham Study,” Ann. Intern. Med., 109(1), pp. 18-24.
3. Segal, N. A., Anderson, D. D., Iyer, K. S., Baker, J., Torner, J. C., Lynch, J. A., Felson, D. T., Lewis, C. E., and Brown, T. D., 2009, “Baseline Articular Contact Stress Levels Predict Incident Symptomatic Knee Osteoarthritis Development in the MOST Cohort,” J. Orthop. Res., 27(12), pp. 1562-1568.
4. Buckwalter, J., Mow, V., and Ratcliffe, A., 1994, “Restoration of Injured or Degenerated Articular Cartilage,” J. Am. Acad. Orthop. Surg., 2(4), pp. 192-201.
5. Guilak, F., and Hung, C. T., 2005, “Physical Regulation of Cartilage Metabolism,” Basic Orthopaedic Biomechanics and Mechano-Biology, V. C. Mow and R. Huiskes, eds., Lippincott Williams & Wilkins, Philadelphia, pp. 259-300.
6. Carter, D. R., Beaupre, G. S., Wong, M., Smith, R. L., Andriacchi, T. P., and Schurman, D. J., 2004, “The Mechanobiology of Articular Cartilage Development and Degeneration,” Clin. Orthop. Relat. Res., (427 Suppl), pp. S69-S77.
7. Gerwin, N., Bendele, A. M., Glasson, S., and Carlson, C. S., 2010, “The OARSI Histopathology Initiative-Recommendations for Histological Assessments of Osteoarthritis in the Rat,” Osteoarthritis Cartilage, 18(Suppl 3), pp. S24-S34.
8. Roemhildt, M. L., Coughlin, K. M., Peura, G. D., Badger, G. J., Churchill, D., Fleming, B. C., and Beynnon, B. D., 2010, “Effects of Increased Chronic Loading on Articular Cartilage Material Properties in the Lapine Tibio-Femoral Joint,” J. Biomech., 43(12), pp. 2301-2308.
9. Roemhildt, M. L., Fleming, B. C., Beynnon, B. D., and Churchill, D., 2009, “101 In Vitro Validation of a Varus Loading Device in the Rabbit Knee” Osteoarthritis Cartilage, 17(Suppl 1), p. S62.
10. Roemhildt, M. L., Beynnon, B. D., Gardner-Morse, M., Badger, G., and Grant, C., 2012, “Changes Induced by Chronic In Vivo Load Alteration in the Tibiofemoral Joint of Mature Rabbits,” J. Orthop. Res., 30(9), pp. 1413-1422.
11. Roemhildt, M. L., Gardner-Morse, M., Rowell, C., Beynnon, B. D., and Badger, G. J., 2010, “Gait Alterations in Rats Following Attachment of a Device and Application of Altered Knee Loading,” J. Biomech., 43(16), pp. 3227-3231.
12. Mak, A. F., Lai, W. M., and Mow, V. C., 1987, “Biphasic Indentation of Articular Cartilage-I. Theoretical Analysis,” J. Biomech., 20(7), pp. 703-714.
13. Mow, V. C., Gibbs, M. C., Lai, W. M., Zhu, W. B., and Athanasiou, K. A., 1989, “Biphasic Indentation of Articular Cartilage-II. A Numerical Algorithm and an Experimental Study,” J. Biomech., 22(8-9), pp. 853-861.
14. Roemhildt, M. L., Coughlin, K. M., Peura, G. D., Fleming, B. C., and Beynnon, B. D., 2006, “Material Properties of Articular Cartilage in the Rabbit Tibial Plateau,” J. Biomech., 39(12), pp. 2331-2337.
15. Gardner-Morse, M. G., Tacy, N. J., Beynnon, B. D., and Roemhildt, M. L., 2010, “In Situ Microindentation for Determining Local Subchondral Bone Compressive Modulus,” J. Biomech. Eng., 132(9), p. 094502.
16. Kiviranta, I., Tammi, M., Jurvelin, J., Saamanen, A. M., and Helminen, H. J., 1984, “Fixation, Decalcification, and Tissue Processing Effects on Articular Cartilage Proteoglycans,” Histochemistry, 80(6), pp. 569-573.
17. Schmitz, N., Laverty, S., Kraus, V. B., and Aigner, T., 2010, “Basic Methods in Histopathology of Joint Tissues,” Osteoarthritis Cartilage, 18(Suppl 3), pp. S113-S116.
18. Carmer, S. G., and Swanson, S. A., 1973, “An Evaluation of Ten Pairwise Multiple Comparisons Procedures by Monte Carlo Methods,” J. Am. Stat. Assoc., 68(341), pp. 66-74.
19. O’Connor, K. M., 1997, “Unweighting Accelerates Tidemark Advancement in Articular Cartilage at the Knee Joint of Rats,” J. Bone Miner. Res., 12(4), pp. 580-589.
20. Wei, L., Hjerpe, A., Brismar, B. H., and Svensson, O., 2001, “Effect of Load on Articular Cartilage Matrix and the Development of Guinea-Pig Osteoarthritis,” Osteoarthritis Cartilage, 9(5), pp. 447-453.
21. Vanwanseele, B., Eckstein, F., Knecht, H., Stussi, E., and Spaepen, A., 2002, “Knee Cartilage of Spinal Cord-Injured Patients Displays Progressive Thinning in the Absence of Normal Joint Loading and Movement,” Arthritis Rheum., 46(8), pp. 2073-2078.
22. Intema, F., Van Roermund, P. M., Marijnissen, A. C. A., Cotofana, S., Eckstein, F., Castelein, R. M., Bijlsma, J. W. J., Mastbergen, S. C., and Lafeber, F. P. J. G., 2011, “Tissue Structure Modification in Knee Osteoarthritis by Use of Joint Distraction: An Open 1-Year Pilot Study,” Ann. Rheum. Dis., 70(8), pp. 1441-1446.
23. Noyes, F. R., Schipplein, O. D., Andriachhi, T. P., Saddemi, S. R., and Weise, M., 1992, “The Anterior Cruciate Ligament-Deficient Knee With Varus Alignment: An Analysis of Gait Adaptations and Dynamic Joint Loadings,” Am. J. Sports Med., 20(6), pp. 707-716.
24. Roemhildt, M. L., Anderson, K., Beynnon, B. D., and Gardner-Morse, M., 2010, “235 Region Specific Cellularity of Articular Cartilage in the Tibial Plateau of the Mature Spague-Dawley Rat,” Osteoarthritis Cartilage, 18(Suppl 2), p. S108.
25. Meachim, G., and Collins, D. H., 1962, “Cell Counts of Normal and Osteo-Arthritic Articular Cartilage in Relation to the Uptake of Sulphate (35SO4) In Vitro,” Ann. Rheum. Dis., 21(1), pp. 45-50.
26. Vignon, E., Arlot, M., and Vignon, G., 1977, “The Cellularity of Fibrillated Articular Cartilage. A Comparative Study of Age-Related and Osteoarthrotic Cartilage Lesions From the Human Femoral Head,” Pathol. Biol., 25(1), pp. 29-32.