Association of 14-bp insertion/deletion polymorphism of HLA-G gene with unexplained recurrent spontaneous abortion: A meta-analysis

Tissue Antigens

Volumn 81, Issue 2, 2013, Pages 108-115

  Wang, X ^a   Jiang, W ^a   Zhang, D ^a  

^a QINGDAO UNIVERSITY   (China)

Author keywords

HLA G; Meta analysis; Polymorphism; Unexplained recurrent spontaneous abortion

Indexed keywords

HLA G ANTIGEN;

ADULT; ARTICLE; CLINICAL PRACTICE; CONTROLLED STUDY; FEMALE; FEMALE INFERTILITY; GENE DELETION; GENE EXPRESSION; GENE INSERTION; GENETIC ASSOCIATION; GENETIC HETEROGENEITY; GENETIC LINKAGE; GENETIC RISK; HARDY WEINBERG DISTRIBUTION LAW; HUMAN; MAJOR CLINICAL STUDY; META ANALYSIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SINGLE NUCLEOTIDE POLYMORPHISM; SPONTANEOUS ABORTION; UNEXPLAINED RECURRENT SPONTANEOUS ABORTION;

ABORTION, HABITUAL; BASE PAIRING; FEMALE; GENETIC ASSOCIATION STUDIES; GENETIC HETEROGENEITY; GENETIC PREDISPOSITION TO DISEASE; HLA-G ANTIGENS; HUMANS; INDEL MUTATION; ODDS RATIO; POLYMORPHISM, GENETIC; PREGNANCY; PUBLICATION BIAS;

EID: 84872668347     PISSN: 00012815     EISSN: 13990039     Source Type: Journal    
DOI: 10.1111/tan.12056     Document Type: Article

References (34)

1. Jauniaux E, Farquharson RG, Christiansen OB, Exalto N. Evidence-based guidelines for the investigation and medical treatment of recurrent miscarriage. Hum Reprod 2006: 21: 2216-22.
2. Coulam CB, Clark DA, Beer AE et al. Current clinical options for diagnosis and treatment of recurrent spontaneous abortion. Clinical Guidelines Recommendation Committee for Diagnosis and Treatment of Recurrent Spontaneous Abortion. Am J Reprod Immunol 1997: 38: 57-74.
3. ACOG practice bulletin. Management of recurrent pregnancy loss. Number 24, February 2001. (Replaces Technical Bulletin Number 212, September 1995). American College of Obstetricians and Gynecologists. Int J Gynaecol Obstet 2002: 78: 179-90.
4. Hunt J, Orr H. HLA and maternal-fetal recognition. FASEB J 1992: 6: 2344-8.
5. Le Bouteiller P, Legrand-Abravanel F, Solier C. Soluble HLA-G1 at the materno-foetal interface-a review. Placenta 2003: 24: S10-5.
6. LeMaoult J, Le Discorde M, Rouas-Freiss N et al. Biology and functions of human leukocyte antigen-G in health and sickness*. Tissue Antigens 2003: 62: 273-84.
7. Hunt JS, Petroff MG, McIntire RH, Ober C. HLA-G and immune tolerance in pregnancy. FASEB J 2005: 19: 681-93.
8. Dahl M, Hviid TVF. Human leucocyte antigen class Ib molecules in pregnancy success and early pregnancy loss. Hum Reprod Update 2012: 18: 92-109.
9. O'brien M, McCarthy T, Jenkins D et al. Altered HLA-G transcription in pre-eclampsia is associated with allele specific inheritance: possible role of the HLA-G gene in susceptibility to the disease. Cell Mol Life Sci 2001: 58: 1943-9.
10. Hviid TV, Hylenius S, Rorbye C, Nielsen LG. HLA-G allelic variants are associated with differences in the HLA-G mRNA isoform profile and HLA-G mRNA levels. Immunogenetics 2003: 55: 63-79.
11. Rebmann V, van der Ven K, Passler M, Pfeiffer K, Krebs D, Grosse-Wilde H. Association of soluble HLA-G plasma levels with HLA-G alleles. Tissue Antigens 2001: 57: 15-21.
12. Chen XY, Yan WH, Lin A, Xu HH, Zhang JG, Wang XX. The 14bp deletion polymorphisms in HLA-G gene play an important role in the expression of soluble HLA-G in plasma. Tissue Antigens 2008: 72: 335-41.
13. Harrison GA, Humphrey KE, Jakobsen IB, Cooper DW. A 14bp deletion polymorphism in the HLA-G gene. Hum Mol Genet 1993: 2: 2200.
14. Higgins JP, Thompson SG, Deeks JJ, Altman DG. Measuring inconsistency in meta-analyses. BMJ 2003: 327: 557-60.
15. DerSimonian R, Laird N. Meta-analysis in clinical trials. Control Clin Trials 1986: 7: 177-88.
16. Khoury MJ, Little J, Gwinn M, Ioannidis JP. On the synthesis and interpretation of consistent but weak gene-disease associations in the era of genome-wide association studies. Int J Epidemiol 2007: 36: 439-45.
17. Ioannidis JP. Commentary: grading the credibility of molecular evidence for complex diseases. Int J Epidemiol 2006: 35: 572-578; discussion 593-576.
18. Peters JL, Sutton AJ, Jones DR, Abrams KR, Rushton L. Comparison of two methods to detect publication bias in meta-analysis. JAMA 2006: 295: 676-80.
19. Xue S, Yang J, Yao F, Xu L, Fan L. Recurrent spontaneous abortions patients have more -14bp/+14bp heterozygotes in the 3′UT region of the HLA-G gene in a Chinese Han population. Tissue Antigens 2007: 69 (Suppl 1): 153-5.
20. Shao J, Hu D, Chen XJ, Liu Y, Wang Z. Relationship of polymorphism of HLA-G 14bp and the expression of HLA-G mRNA with unexplained recurrent spontaneous abortion. Chin J Pract Gynaecol Obstet 2011: 27: 698-701.
21. Shankarkumar U, Shankarkumar A, Chedda Z, Ghosh K. Role of 14-bp deletion/insertion polymorphism in exon 8 of the HLA-G gene in recurrent spontaneous abortion patients. J Hum Reprod Sci 2011: 4: 143-6.
22. Sipak-Szmigiel O, Cybulski C, Lubinski J, Ronin-Walknowska E. HLA-G polymorphism in a Polish population and reproductive failure. Tissue Antigens 2008: 71: 67-71.
23. Vargas RG, Sarturi PR, Mattar SB et al. Association of HLA-G alleles and 3′ UTR 14bp haplotypes with recurrent miscarriage in Brazilian couples. Hum Immunol 2011: 72: 479-85.
24. Hviid TV, Hylenius S, Lindhard A, Christiansen OB. Association between human leukocyte antigen-G genotype and success of in vitro fertilization and pregnancy outcome. Tissue Antigens 2004: 64: 66-9.
25. Yan WH, Lin A, Chen XJ et al. Association of the maternal 14-bp insertion polymorphism in the HLA-G gene in women with recurrent spontaneous abortions. Tissue Antigens 2006: 68: 521-3.
26. Tripathi P, Abbas A, Naik S, Agrawal S. Role of 14-bp deletion in the HLA-G gene in the maintenance of pregnancy. Tissue Antigens 2004: 64: 706-10.
27. Aruna M, Sirisha PV, Andal Bhaskar S, Tarakeswari S, Thangaraj K, Reddy BM. Role of 14-bp insertion/deletion polymorphism in HLA-G among Indian women with recurrent spontaneous abortions. Tissue Antigens 2011: 77: 131-5.
28. Suryanarayana V, Rao L, Kanakavalli M et al. Association between novel HLA-G genotypes and risk of recurrent miscarriages: a case-control study in a South Indian population. Reprod Sci 2008: 15: 817-24.
29. Zhu Y, Huo Z, Lai J et al. Case-control study of a HLA-G 14-bp insertion-deletion polymorphism in women with recurrent miscarriages. Scand J Immunol 2010: 71: 52-4.
30. Jassem RM, Shani WS, Loisel DA, Sharief M, Billstrand C, Ober C. HLA-G polymorphisms and soluble HLA-G protein levels in women with recurrent pregnancy loss from Basrah province in Iraq. Hum Immunol 2012: 73: 811-7.
31. Christiansen OB, Kolte AM, Dahl M et al. Maternal homozygocity for a 14 base pair insertion in exon 8 of the HLA-G gene and carriage of HLA class II alleles restricting HY immunity predispose to unexplained secondary recurrent miscarriage and low birth weight in children born to these patients. Hum Immunol 2012: 73: 699-705.
32. Zhao Y, Zheng M, Zhang G, Zhang Y, Hua A, He J. Serum level of sHLA-G and HLA-G14bp insertion / deletion polymorphism with recurrent miscarriage. Shanxi Med J 2009: 38; 390-1.
33. Hviid TV, Rizzo R, Melchiorri L, Stignani M, Baricordi OR. Polymorphism in the 5′ upstream regulatory and 3′ untranslated regions of the HLA-G gene in relation to soluble HLA-G and IL-10 expression. Hum Immunol 2006: 67: 53-62.
34. Munafo MR, Flint J. Meta-analysis of genetic association studies. Trends Genet 2004: 20: 439-44.