Recurrent spontaneous abortions patients have more -14 bp/+14 bp heterozygotes in the 3′UT region of the HLA-G gene in a Chinese Han population

Tissue Antigens

Volumn 69, Issue SUPPL. 1, 2007, Pages 153-155

  Xue, S ^a   Yang, J ^a   Yao, F ^a   Xu, L ^a   Fan, L ^a  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

14 bp deletion polymorphism; HLA G; Pregnancy; Recurrent spontaneous abortion

Indexed keywords

ETHIDIUM BROMIDE; HLA G ANTIGEN;

3' UNTRANSLATED REGION; CHINESE; CLINICAL ARTICLE; CONFERENCE PAPER; CONTROLLED STUDY; CORRELATION ANALYSIS; DNA ISOLATION; DNA POLYMORPHISM; EXON; FEMALE; FERTILITY; GENE AMPLIFICATION; GENE DELETION; HETEROZYGOTE; HUMAN; IMMUNOHISTOCHEMISTRY; POLYACRYLAMIDE GEL ELECTROPHORESIS; POLYMERASE CHAIN REACTION; POPULATION GENETICS; PREGNANCY DISORDER; PRIORITY JOURNAL; RACE DIFFERENCE; RECURRENT DISEASE; SPONTANEOUS ABORTION; STAINING;

3' UNTRANSLATED REGIONS; ABORTION, HABITUAL; ABORTION, SPONTANEOUS; BASE SEQUENCE; CHINA; FEMALE; GENE FREQUENCY; HETEROZYGOTE; HISTOCOMPATIBILITY ANTIGENS CLASS I; HLA ANTIGENS; HUMANS; MOLECULAR SEQUENCE DATA; POLYMERASE CHAIN REACTION; PREGNANCY;

EID: 34247179195     PISSN: 00012815     EISSN: 13990039     Source Type: Journal    
DOI: 10.1111/j.1399-0039.2006.763_7.x     Document Type: Conference Paper

References (16)

1. Scott JR, Rote NS, Branch DW. Immunologic aspects of recurrent abortion and fetal death. Obstet Gynecol 1987: 70: 645-56.
2. Stephenson MD. Frequency of factors associated with habitual abortion in 197 couples. Fertil Steril 1996: 66: 24-9.
3. Hviid TV, Hylenius S, Hoegh AM, Kruse C, Christiansen OB. HLA-Gpolymorphisms in couples with recurrent spontaneous abortions. Tissue Antigens 2002: 60: 122-32.
4. Yamashita T, Fujii T, Tokunaga K et al. Analysis of human leukocyte antigen-G polymorphism including intron 4 in Japanese couples with habitual abortion. Am J Reprod Immunol 1999: 41: 159-63.
5. Pfeiffer KA, Fimmers R, Engels G, van der Ven H, van der Ven K. The HLA-G genotype is potentially associated with idiopathic recurrent spontaneous abortion. Mol Hum Reprod 2001: 7: 373-8.
6. Aldrich CL, Stephenson MD, Karrison T et al. HLA-G genotypes and pregnancy outcome in couples with unexplained recurrent miscarriage. Mol Hum Reprod 2001: 7: 1167-72.
7. Pfeiffer KA, Rebmann V, Passler Met al. Soluble HLA levels in early pregnancy after in vitro fertilization. Hum Immunol 2000: 61: 559-64.
8. Karhukorpi J, Laitinen T, Tiilikainen AS. HLA-G polymorphism in Finnish couples with recurrent spontaneous miscarriage. Br J Obstet Gynaecol 1997: 104: 1212-4.
9. Penzes M, Rajczy K, Gyodi E, Reti M, Feher E, Petranyi G. HLA-G gene polymorphism in the normal population and in recurrent spontaneous abortion in Hungary. Transplant Proc 1999: 31: 1832-3.
10. Miller SA, Dykes DD, Polesky HF. A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res 1988: 16: 1215.
11. Yan WH, Fan LA, Yang JQ, Xu LD, Ge Y, Yao FJ. HLA-G polymorphism in a Chinese Han population with recurrent spontaneous abortion. Int J Immunogenet 2006: 33: 55-8.
12. Castro MJ, Morales P, Martinez-Laso J et al. Evolution of MHC-G in humans and primates based on three new 3′UT polymorphisms. Hum Immunol 2000: 61: 1157-63.
13. Harrison GA, Humphrey KE, Jakobsen IB, Cooper DW. A14 bp deletion polymorphism in the HLA-G gene. Hum Mol Genet 1993: 2: 2200.
14. Hiby SE, King A, Sharkey A, Loke YW. Molecular studies of trophoblast HLA-G: polymorphism, isoforms, imprinting and expression in preimplantation embryo. Tissue Antigens 1999: 53: 1-13.
15. Rousseau P, Le Discorde M, Mouillot G, Marcou C, Carosella ED, Moreau P. The 14 bp deletion-insertion polymorphism in the 3′ UT region of the HLA-G gene influences HLA-G mRNA stability. Hum Immunol 2003: 64: 1005-10.
16. Tripathi P, Abbas A, Naik S, Agrawal S. Role of 14-bp deletion in the HLA-G gene in the maintenance of pregnancy. Tissue Antigens 2004: 64: 706-10.