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Volumn 9, Issue 1, 2013, Pages 119-129

Holistic metabonomic profiling of urine affords potential early diagnosis for bladder and kidney cancers

Author keywords

Bladder cancer; Early diagnosis; Kidney cancer; Metabonomics; Urine

Indexed keywords

ACEGLUTAMIDE; BETAINE; CARNITINE; HIPPURIC ACID; PHENYLACTEYLGLUTAMINE; TAURINE; UNCLASSIFIED DRUG;

EID: 84872651699     PISSN: 15733882     EISSN: 15733890     Source Type: Journal    
DOI: 10.1007/s11306-012-0433-5     Document Type: Article
Times cited : (22)

References (45)
  • 1
    • 77955435782 scopus 로고    scopus 로고
    • Integrated ionization approach for RRLC-MS/MS-based metabonomics: finding potential biomarkers for lung cancer
    • doi:10.1021/pr100265g
    • An, Z. L., Chen, Y. H., Zhang, R. P., Song, Y. M., Sun, J. H., He, J. M., et al. (2010). Integrated ionization approach for RRLC-MS/MS-based metabonomics: finding potential biomarkers for lung cancer. Journal of Proteome Research, 9(8), 4071-4081. doi: 10. 1021/pr100265g.
    • (2010) Journal of Proteome Research , vol.9 , Issue.8 , pp. 4071-4081
    • An, Z.L.1    Chen, Y.H.2    Zhang, R.P.3    Song, Y.M.4    Sun, J.H.5    He, J.M.6
  • 2
    • 0037292138 scopus 로고    scopus 로고
    • Visualizing metabolic changes in breast-cancer tissue using 1H-NMR spectroscopy and self-organizing maps
    • doi:10.1002/nbm.797
    • Beckonert, O., Monnerjahn, J., Bonk, U., & Leibfritz, D. (2003). Visualizing metabolic changes in breast-cancer tissue using 1H-NMR spectroscopy and self-organizing maps. NMR in Biomedicine, 16(1), 1-11. doi: 10. 1002/nbm. 797.
    • (2003) NMR in Biomedicine , vol.16 , Issue.1 , pp. 1-11
    • Beckonert, O.1    Monnerjahn, J.2    Bonk, U.3    Leibfritz, D.4
  • 3
    • 36148968834 scopus 로고    scopus 로고
    • Evaluation of a protocol for metabolic profiling studies on human blood plasma by combined ultra-performance liquid chromatography/mass spectrometry: from extraction to data analysis
    • doi:10.1016/j.ab.2007.09.037
    • Bruce, S. J., Jonsson, P., Antti, H., Cloarec, O., Trygg, J., Marklund, S. L., et al. (2008). Evaluation of a protocol for metabolic profiling studies on human blood plasma by combined ultra-performance liquid chromatography/mass spectrometry: from extraction to data analysis. Analytical Biochemistry, 372(2), 237-249. doi: 10. 1016/j. ab. 2007. 09. 037.
    • (2008) Analytical Biochemistry , vol.372 , Issue.2 , pp. 237-249
    • Bruce, S.J.1    Jonsson, P.2    Antti, H.3    Cloarec, O.4    Trygg, J.5    Marklund, S.L.6
  • 4
    • 34249335649 scopus 로고    scopus 로고
    • OPLS discriminant analysis: combining the strengths of PLS-DA and SIMCA classification
    • doi:10.1002/cem.1006
    • Bylesjö, M., Rantalainen, M., Cloarec, O., Nicholson, J. K., Holmes, E., & Trygg, J. (2006). OPLS discriminant analysis: combining the strengths of PLS-DA and SIMCA classification. Journal of Chemometrics, 20(8-10), 341-351. doi: 10. 1002/cem. 1006.
    • (2006) Journal of Chemometrics , vol.20 , Issue.8-10 , pp. 341-351
    • Bylesjö, M.1    Rantalainen, M.2    Cloarec, O.3    Nicholson, J.K.4    Holmes, E.5    Trygg, J.6
  • 6
    • 69249140995 scopus 로고    scopus 로고
    • Metabonomics study of liver cancer based on ultra performance liquid chromatography coupled to mass spectrometry with HILIC and RPLC separations
    • doi:10.1016/j.aca.2009.03.039
    • Chen, J., Wang, W., Lv, S., Yin, P., Zhao, X., Lu, X., et al. (2009). Metabonomics study of liver cancer based on ultra performance liquid chromatography coupled to mass spectrometry with HILIC and RPLC separations. Analytica Chimica Acta, 650(1), 3-9. doi: 10. 1016/j. aca. 2009. 03. 039.
    • (2009) Analytica Chimica Acta , vol.650 , Issue.1 , pp. 3-9
    • Chen, J.1    Wang, W.2    Lv, S.3    Yin, P.4    Zhao, X.5    Lu, X.6
  • 7
    • 34447564234 scopus 로고    scopus 로고
    • Metabolomics: Available results, current research projects in breast cancer, and future applications
    • doi:10.1200/Jco.2006.09.7550
    • Claudino, W. M., Quattrone, A., Biganzoli, L., Pestrin, M., Bertini, I., & Di Leo, A. (2007). Metabolomics: Available results, current research projects in breast cancer, and future applications. Journal of Clinical Oncology, 25(19), 2840-2846. doi: 10. 1200/Jco. 2006. 09. 7550.
    • (2007) Journal of Clinical Oncology , vol.25 , Issue.19 , pp. 2840-2846
    • Claudino, W.M.1    Quattrone, A.2    Biganzoli, L.3    Pestrin, M.4    Bertini, I.5    Di Leo, A.6
  • 8
    • 33646198860 scopus 로고    scopus 로고
    • Pharmaco-metabonomic phenotyping and personalized drug treatment
    • doi:10.1038/nature04648
    • Clayton, T. A., Lindon, J. C., Cloarec, O., Antti, H., Charuel, C., Hanton, G., et al. (2006). Pharmaco-metabonomic phenotyping and personalized drug treatment. Nature, 440(7087), 1073-1077. doi: 10. 1038/nature04648.
    • (2006) Nature , vol.440 , Issue.7087 , pp. 1073-1077
    • Clayton, T.A.1    Lindon, J.C.2    Cloarec, O.3    Antti, H.4    Charuel, C.5    Hanton, G.6
  • 9
    • 28844484134 scopus 로고    scopus 로고
    • Renal-cell carcinoma
    • doi:10.1056/NEJMra043172
    • Cohen, H. T., & McGovern, F. J. (2005). Renal-cell carcinoma. New England Journal of Medicine, 353(23), 2477-2490. doi: 10. 1056/NEJMra043172.
    • (2005) New England Journal of Medicine , vol.353 , Issue.23 , pp. 2477-2490
    • Cohen, H.T.1    McGovern, F.J.2
  • 10
    • 77957806588 scopus 로고    scopus 로고
    • Metabolomic applications of HILIC-LC-MS
    • doi:10.1002/Mas.20252
    • Cubbon, S., Antonio, C., Wilson, J., & Thomas-Oates, J. (2010). Metabolomic applications of HILIC-LC-MS. Mass Spectrometry Reviews, 29(5), 671-684. doi: 10. 1002/Mas. 20252.
    • (2010) Mass Spectrometry Reviews , vol.29 , Issue.5 , pp. 671-684
    • Cubbon, S.1    Antonio, C.2    Wilson, J.3    Thomas-Oates, J.4
  • 11
    • 36849005017 scopus 로고    scopus 로고
    • Hydrophilic interaction chromatography for mass spectrometric metabonomic studies of urine
    • doi:10.1021/ac071008v
    • Cubbon, S., Bradbury, T., Wilson, J., & Thomas-Oates, J. (2007). Hydrophilic interaction chromatography for mass spectrometric metabonomic studies of urine. Analytical Chemistry, 79(23), 8911-8918. doi: 10. 1021/ac071008v.
    • (2007) Analytical Chemistry , vol.79 , Issue.23 , pp. 8911-8918
    • Cubbon, S.1    Bradbury, T.2    Wilson, J.3    Thomas-Oates, J.4
  • 12
    • 0035902115 scopus 로고    scopus 로고
    • Proliferation, cell cycle and apoptosis in cancer
    • doi:10.1038/35077213
    • Evan, G. I., & Vousden, K. H. (2001). Proliferation, cell cycle and apoptosis in cancer. Nature, 411(6835), 342-348. doi: 10. 1038/35077213.
    • (2001) Nature , vol.411 , Issue.6835 , pp. 342-348
    • Evan, G.I.1    Vousden, K.H.2
  • 13
    • 84856216340 scopus 로고    scopus 로고
    • Quantitative determination of taurine and related biomarkers in urine by liquid chromatography-tandem mass spectrometry
    • doi:10.1007/s00216-011-5491-4
    • Gamagedara, S., Shi, H., & Ma, Y. (2012). Quantitative determination of taurine and related biomarkers in urine by liquid chromatography-tandem mass spectrometry. Analytical and Bioanalytical Chemistry, 402(2), 763-770. doi: 10. 1007/s00216-011-5491-4.
    • (2012) Analytical and Bioanalytical Chemistry , vol.402 , Issue.2 , pp. 763-770
    • Gamagedara, S.1    Shi, H.2    Ma, Y.3
  • 14
    • 45949087351 scopus 로고    scopus 로고
    • Hydrophilic interaction and reversed-phase ultra-performance liquid chromatography TOF-MS for metabonomic analysis of Zucker rat urine
    • doi:10.1002/jssc.200700644
    • Gika, H. G., Theodoridis, G. A., & Wilson, I. D. (2008). Hydrophilic interaction and reversed-phase ultra-performance liquid chromatography TOF-MS for metabonomic analysis of Zucker rat urine. Journal of Separation Science, 31(9), 1598-1608. doi: 10. 1002/jssc. 200700644.
    • (2008) Journal of Separation Science , vol.31 , Issue.9 , pp. 1598-1608
    • Gika, H.G.1    Theodoridis, G.A.2    Wilson, I.D.3
  • 15
    • 34548146614 scopus 로고    scopus 로고
    • Within-day reproducibility of an HPLC-MS-based method for metabonomic analysis: Application to human urine
    • doi:10.1021/Pr070183p
    • Gika, H. G., Theodoridis, G. A., Wingate, J. E., & Wilson, I. D. (2007). Within-day reproducibility of an HPLC-MS-based method for metabonomic analysis: Application to human urine. Journal of Proteome Research, 6(8), 3291-3303. doi: 10. 1021/Pr070183p.
    • (2007) Journal of Proteome Research , vol.6 , Issue.8 , pp. 3291-3303
    • Gika, H.G.1    Theodoridis, G.A.2    Wingate, J.E.3    Wilson, I.D.4
  • 17
    • 43049154785 scopus 로고    scopus 로고
    • Detection of bladder cancer in human urine by metabolomic profiling using high performance liquid chromatography/mass spectrometry
    • doi:10.1016/j.juro.2008.01.084
    • Issaq, H. J., Nativ, O., Waybright, T., Luke, B., Veenstra, T. D., Issaq, E. J., et al. (2008). Detection of bladder cancer in human urine by metabolomic profiling using high performance liquid chromatography/mass spectrometry. The Journal of Urology, 179(6), 2422-2426. doi: 10. 1016/j. juro. 2008. 01. 084.
    • (2008) The Journal of Urology , vol.179 , Issue.6 , pp. 2422-2426
    • Issaq, H.J.1    Nativ, O.2    Waybright, T.3    Luke, B.4    Veenstra, T.D.5    Issaq, E.J.6
  • 18
    • 63049134550 scopus 로고    scopus 로고
    • Urine metabolomics analysis for kidney cancer detection and biomarker discovery
    • doi:10.1074/mcp.M800165-MCP200
    • Kim, K., Aronov, P., Zakharkin, S. O., Anderson, D., Perroud, B., Thompson, I. M., et al. (2009). Urine metabolomics analysis for kidney cancer detection and biomarker discovery. Molecular and Cellular Proteomics, 8(3), 558-570. doi: 10. 1074/mcp. M800165-MCP200.
    • (2009) Molecular and Cellular Proteomics , vol.8 , Issue.3 , pp. 558-570
    • Kim, K.1    Aronov, P.2    Zakharkin, S.O.3    Anderson, D.4    Perroud, B.5    Thompson, I.M.6
  • 19
    • 78650737804 scopus 로고    scopus 로고
    • Advances in structure elucidation of small molecules using mass spectrometry
    • doi:10.1007/s12566-010-0015-9
    • Kind, T., & Fiehn, O. (2010). Advances in structure elucidation of small molecules using mass spectrometry. Bioanalytical Reviews, 2(1), 23-60. doi: 10. 1007/s12566-010-0015-9.
    • (2010) Bioanalytical Reviews , vol.2 , Issue.1 , pp. 23-60
    • Kind, T.1    Fiehn, O.2
  • 20
    • 33947216093 scopus 로고    scopus 로고
    • A comprehensive urinary metabolomic approach for identifying kidney cancer
    • doi:10.1016/j.ab.2007.01.028
    • Kind, T., Tolstikov, V., Fiehn, O., & Weiss, R. H. (2007). A comprehensive urinary metabolomic approach for identifying kidney cancer. Analytical Biochemistry, 363(2), 185-195. doi: 10. 1016/j. ab. 2007. 01. 028.
    • (2007) Analytical Biochemistry , vol.363 , Issue.2 , pp. 185-195
    • Kind, T.1    Tolstikov, V.2    Fiehn, O.3    Weiss, R.H.4
  • 21
    • 74949142102 scopus 로고    scopus 로고
    • Evaluating overall survival and competing risks of death in patients with localized renal cell carcinoma using a comprehensive nomogram
    • doi:10.1200/jco.2009.22.4816
    • Kutikov, A., Egleston, B. L., Wong, Y.-N., & Uzzo, R. G. (2010). Evaluating overall survival and competing risks of death in patients with localized renal cell carcinoma using a comprehensive nomogram. Journal of Clinical Oncology, 28(2), 311-317. doi: 10. 1200/jco. 2009. 22. 4816.
    • (2010) Journal of Clinical Oncology , vol.28 , Issue.2 , pp. 311-317
    • Kutikov, A.1    Egleston, B.L.2    Wong, Y.-N.3    Uzzo, R.G.4
  • 22
    • 79952436750 scopus 로고    scopus 로고
    • LC-MS based serum metabonomic analysis for renal cell carcinoma diagnosis, staging, and biomarker discovery
    • doi:10.1021/pr101161u
    • Lin, L., Hang, W., Huang, Z. Z., Gao, Y., Yan, X. M., & Xing, J. C. (2011). LC-MS based serum metabonomic analysis for renal cell carcinoma diagnosis, staging, and biomarker discovery. Journal of Proteome Research, 10(3), 1396-1405. doi: 10. 1021/pr101161u.
    • (2011) Journal of Proteome Research , vol.10 , Issue.3 , pp. 1396-1405
    • Lin, L.1    Hang, W.2    Huang, Z.Z.3    Gao, Y.4    Yan, X.M.5    Xing, J.C.6
  • 23
    • 0242608613 scopus 로고    scopus 로고
    • The genetic basis of cancer of the kidney
    • doi:10.1097/01.ju.0000096060.92397.ed
    • Linehan, W. M., Walther, M. M., & Zbar, B. (2003). The genetic basis of cancer of the kidney. Journal of Urology, 170(6), 2163-2172. doi: 10. 1097/01. ju. 0000096060. 92397. ed.
    • (2003) Journal of Urology , vol.170 , Issue.6 , pp. 2163-2172
    • Linehan, W.M.1    Walther, M.M.2    Zbar, B.3
  • 24
    • 0026021017 scopus 로고
    • Abnormalities of essential fatty acid distribution in the plasma phospholipids of patients with bladder cancer
    • McClinton, S., Moffat, L. E., Horrobin, D. F., & Manku, M. S. (1991). Abnormalities of essential fatty acid distribution in the plasma phospholipids of patients with bladder cancer. British Journal of Cancer, 63(2), 314-316.
    • (1991) British Journal of Cancer , vol.63 , Issue.2 , pp. 314-316
    • McClinton, S.1    Moffat, L.E.2    Horrobin, D.F.3    Manku, M.S.4
  • 25
    • 0037395628 scopus 로고    scopus 로고
    • Renal-cell carcinoma: tumour markers, T-cell epitopes, and potential for new therapies
    • doi:10.1016/S1470-2045(03)01044-1
    • Michael, A., & Pandha, H. S. (2003). Renal-cell carcinoma: tumour markers, T-cell epitopes, and potential for new therapies. Lancet Oncology, 4(4), 215-223. doi: 10. 1016/S1470-2045(03)01044-1.
    • (2003) Lancet Oncology , vol.4 , Issue.4 , pp. 215-223
    • Michael, A.1    Pandha, H.S.2
  • 26
    • 75949121210 scopus 로고    scopus 로고
    • Molecular screening for bladder cancer: progress and potential
    • doi:10.1038/nrurol.2009.236
    • Mitra, A. P., & Cote, R. J. (2010). Molecular screening for bladder cancer: progress and potential. Nature Reviews Urology, 7(1), 11-20. doi: 10. 1038/nrurol. 2009. 236.
    • (2010) Nature Reviews Urology , vol.7 , Issue.1 , pp. 11-20
    • Mitra, A.P.1    Cote, R.J.2
  • 27
    • 53549093030 scopus 로고    scopus 로고
    • Proteomics and genomics of urinary bladder cancer
    • doi:0.1002/prca.200780089
    • Mohammed, S. I., & Rahman, M. (2008). Proteomics and genomics of urinary bladder cancer. Proteomics Clinical Application, 2(9), 1194-1207. doi: 0. 1002/prca. 200780089.
    • (2008) Proteomics Clinical Application , vol.2 , Issue.9 , pp. 1194-1207
    • Mohammed, S.I.1    Rahman, M.2
  • 28
    • 0027565016 scopus 로고
    • 1H NMR spectroscopy of colon tumors and normal mucosal biopsies; elevated taurine levels and reduced polyethyleneglycol absorption in tumors may have diagnostic significance
    • doi:10.1002/nbm.1940060202
    • Moreno, A., Rey, M., Montane, J. M., Alonso, J., & Arús, C. (1993). 1H NMR spectroscopy of colon tumors and normal mucosal biopsies; elevated taurine levels and reduced polyethyleneglycol absorption in tumors may have diagnostic significance. NMR in Biomedicine, 6(2), 111-118. doi: 10. 1002/nbm. 1940060202.
    • (1993) NMR in Biomedicine , vol.6 , Issue.2 , pp. 111-118
    • Moreno, A.1    Rey, M.2    Montane, J.M.3    Alonso, J.4    Arús, C.5
  • 29
    • 77951744263 scopus 로고    scopus 로고
    • Urinary biomarkers for the early diagnosis of kidney cancer
    • doi:10.4065/mcp.20090709
    • Morrissey, J. J., London, A. N., Luo, J. Q., & Kharasch, E. D. (2010). Urinary biomarkers for the early diagnosis of kidney cancer. Mayo Clinic Proceedings, 85(5), 413-421. doi: 10. 4065/mcp. 20090709.
    • (2010) Mayo Clinic Proceedings , vol.85 , Issue.5 , pp. 413-421
    • Morrissey, J.J.1    London, A.N.2    Luo, J.Q.3    Kharasch, E.D.4
  • 30
    • 0032694577 scopus 로고    scopus 로고
    • Metabonomics': understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data
    • doi:10.1080/004982599238047
    • Nicholson, J. K., Lindon, J. C., & Holmes, E. (1999). 'Metabonomics': understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data. Xenobiotica, 29(11), 1181-1189. doi: 10. 1080/004982599238047.
    • (1999) Xenobiotica , vol.29 , Issue.11 , pp. 1181-1189
    • Nicholson, J.K.1    Lindon, J.C.2    Holmes, E.3
  • 31
    • 68049147272 scopus 로고    scopus 로고
    • Radiochemotherapy for bladder cancer
    • doi:10.1016/j.clon.2009.05.005
    • Ott, O. J., Rödel, C., Weiss, C., Wittlinger, M., St. Krause, F., Dunst, J., et al. (2009). Radiochemotherapy for bladder cancer. Clinical Oncology, 21(7), 557-565. doi: 10. 1016/j. clon. 2009. 05. 005.
    • (2009) Clinical Oncology , vol.21 , Issue.7 , pp. 557-565
    • Ott, O.J.1    Rödel, C.2    Weiss, C.3    Wittlinger, M.4    St.Krause, F.5    Dunst, J.6
  • 32
    • 77952040671 scopus 로고    scopus 로고
    • Metabolomic screening and star pattern recognition by urinary amino acid profile analysis from bladder cancer patients
    • doi:10.1007/s11306-010-0199-6
    • Paik, M. J., Kim, J. W., Lee, G., Moon, S. M., Park, M. J., Hong, S. K., et al. (2010). Metabolomic screening and star pattern recognition by urinary amino acid profile analysis from bladder cancer patients. Metabolomics, 6(2), 202-206. doi: 10. 1007/s11306-010-0199-6.
    • (2010) Metabolomics , vol.6 , Issue.2 , pp. 202-206
    • Paik, M.J.1    Kim, J.W.2    Lee, G.3    Moon, S.M.4    Park, M.J.5    Hong, S.K.6
  • 34
    • 34548324040 scopus 로고    scopus 로고
    • Standardization of ROC curve areas for diagnostic evaluation of liver fibrosis markers based on prevalences of fibrosis stages
    • doi:10.1373/clinchem.2007.085795
    • Poynard, T., Halfon, P., Castera, L., Munteanu, M., Imbert-Bismut, F., Ratziu, V., et al. (2007). Standardization of ROC curve areas for diagnostic evaluation of liver fibrosis markers based on prevalences of fibrosis stages. Clinical Chemistry, 53(9), 1615-1622. doi: 10. 1373/clinchem. 2007. 085795.
    • (2007) Clinical Chemistry , vol.53 , Issue.9 , pp. 1615-1622
    • Poynard, T.1    Halfon, P.2    Castera, L.3    Munteanu, M.4    Imbert-Bismut, F.5    Ratziu, V.6
  • 35
    • 42949149708 scopus 로고    scopus 로고
    • Hydrophilic interaction liquid chromatography-tandem mass spectrometry determination of estrogen conjugates in human urine
    • doi:10.1021/ac702613k
    • Qin, F., Zhao, Y. Y., Sawyer, M. B., & Li, X. F. (2008). Hydrophilic interaction liquid chromatography-tandem mass spectrometry determination of estrogen conjugates in human urine. Analytical Chemistry, 80(9), 3404-3411. doi: 10. 1021/ac702613k.
    • (2008) Analytical Chemistry , vol.80 , Issue.9 , pp. 3404-3411
    • Qin, F.1    Zhao, Y.Y.2    Sawyer, M.B.3    Li, X.F.4
  • 36
    • 33744957443 scopus 로고    scopus 로고
    • Microarray analysis and tumor classification
    • doi:10.1056/NEJMra042342
    • Quackenbush, J. (2006). Microarray analysis and tumor classification. New England Journal of Medicine, 354(23), 2463-2472. doi: 10. 1056/NEJMra042342.
    • (2006) New England Journal of Medicine , vol.354 , Issue.23 , pp. 2463-2472
    • Quackenbush, J.1
  • 38
    • 78650375977 scopus 로고    scopus 로고
    • Urine metabolite analysis offers potential early diagnosis of ovarian and breast cancers
    • doi:10.1158/1078-0432.ccr-10-1434
    • Slupsky, C. M., Steed, H., Wells, T. H., Dabbs, K., Schepansky, A., Capstick, V., et al. (2010). Urine metabolite analysis offers potential early diagnosis of ovarian and breast cancers. Clinical Cancer Research, 16(23), 5835-5841. doi: 10. 1158/1078-0432. ccr-10-1434.
    • (2010) Clinical Cancer Research , vol.16 , Issue.23 , pp. 5835-5841
    • Slupsky, C.M.1    Steed, H.2    Wells, T.H.3    Dabbs, K.4    Schepansky, A.5    Capstick, V.6
  • 39
    • 59449097019 scopus 로고    scopus 로고
    • Clinical applications of metabolomics in oncology: A review
    • doi:10.1158/1078-0432.ccr-08-1059
    • Spratlin, J. L., Serkova, N. J., & Eckhardt, S. G. (2009). Clinical applications of metabolomics in oncology: A review. Clinical Cancer Research, 15(2), 431-440. doi: 10. 1158/1078-0432. ccr-08-1059.
    • (2009) Clinical Cancer Research , vol.15 , Issue.2 , pp. 431-440
    • Spratlin, J.L.1    Serkova, N.J.2    Eckhardt, S.G.3
  • 40
    • 77249170742 scopus 로고    scopus 로고
    • Taurine-a possible fingerprint biomarker in non-muscle invasive bladder cancer: A pilot study by 1H NMR spectroscopy
    • doi:10.3233/CBM-2009-0115
    • Srivastavaa, S., Roy, R., Singh, S., Kumar, P., Dalela, D., Sankhwarc, S. N., et al. (2010). Taurine-a possible fingerprint biomarker in non-muscle invasive bladder cancer: A pilot study by 1H NMR spectroscopy. Cancer Biomarkers, 6(1), 11-20. doi: 10. 3233/CBM-2009-0115.
    • (2010) Cancer Biomarkers , vol.6 , Issue.1 , pp. 11-20
    • Srivastavaa, S.1    Roy, R.2    Singh, S.3    Kumar, P.4    Dalela, D.5    Sankhwarc, S.N.6    Goel, A.7    Sonkar, A.A.8
  • 41
    • 79960495785 scopus 로고    scopus 로고
    • Mass spectrometry-based holistic analytical approaches for metabolite profiling in systems biology studies
    • doi:10.1002/mas.20306
    • Theodoridis, G., Gika, H. G., & Wilson, I. D. (2011). Mass spectrometry-based holistic analytical approaches for metabolite profiling in systems biology studies. Mass Spectrometry Reviews, 30(5), 884-906. doi: 10. 1002/mas. 20306.
    • (2011) Mass Spectrometry Reviews , vol.30 , Issue.5 , pp. 884-906
    • Theodoridis, G.1    Gika, H.G.2    Wilson, I.D.3
  • 43
    • 41149120242 scopus 로고    scopus 로고
    • Visualization of GC/TOF-MS-based metabolomics data for identification of biochemically interesting compounds using OPLS class models
    • doi:10.1021/Ac0713510
    • Wiklund, S., Johansson, E., Sjostrom, L., Mellerowicz, E. J., Edlund, U., Shockcor, J. P., et al. (2008). Visualization of GC/TOF-MS-based metabolomics data for identification of biochemically interesting compounds using OPLS class models. Analytical Chemistry, 80(1), 115-122. doi: 10. 1021/Ac0713510.
    • (2008) Analytical Chemistry , vol.80 , Issue.1 , pp. 115-122
    • Wiklund, S.1    Johansson, E.2    Sjostrom, L.3    Mellerowicz, E.J.4    Edlund, U.5    Shockcor, J.P.6
  • 44
    • 77952792141 scopus 로고    scopus 로고
    • Urinary metabonomic study of lung cancer by a fully automatic hyphenated hydrophilic interaction/RPLC-MS system
    • doi:10.1002/jssc.200900798
    • Yang, Q., Shi, X., Wang, Y., Wang, W., He, H., Lu, X., et al. (2010). Urinary metabonomic study of lung cancer by a fully automatic hyphenated hydrophilic interaction/RPLC-MS system. Journal of Separation Science, 33(10), 1495-1503. doi: 10. 1002/jssc. 200900798.
    • (2010) Journal of Separation Science , vol.33 , Issue.10 , pp. 1495-1503
    • Yang, Q.1    Shi, X.2    Wang, Y.3    Wang, W.4    He, H.5    Lu, X.6
  • 45
    • 70349321699 scopus 로고    scopus 로고
    • A metabonomic study of hepatitis B-induced liver cirrhosis and hepatocellular carcinoma by using RP-LC and HILIC coupled with mass spectrometry
    • doi:10.1039/b820224a
    • Yin, P., Wan, D., Zhao, C., Chen, J., Zhao, X., Wang, W., et al. (2009). A metabonomic study of hepatitis B-induced liver cirrhosis and hepatocellular carcinoma by using RP-LC and HILIC coupled with mass spectrometry. Molecular BioSystems, 5(8), 868-876. doi: 10. 1039/b820224a.
    • (2009) Molecular BioSystems , vol.5 , Issue.8 , pp. 868-876
    • Yin, P.1    Wan, D.2    Zhao, C.3    Chen, J.4    Zhao, X.5    Wang, W.6


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