Integrated ionization approach for RRLC-MS/MS-based metabonomics: Finding potential biomarkers for lung cancer

Journal of Proteome Research

Volumn 9, Issue 8, 2010, Pages 4071-4081

  An, Zhuoling ^a   Chen, Yanhua ^a   Zhang, Ruiping ^a   Song, Yongmei ^b   Sun, Jianghao ^a   He, Jiuming ^a   Bai, Jinfa ^a   Dong, Lijia ^b   Zhan, Qimin ^b   Abliz, Zeper ^a  

^a INSTITUTE OF MATERIA MEDICA   (China)

^b PEKING UNION MEDICAL COLLEGE   (China)

Author keywords

APPI; ESI, APCI; integrated ionization approach; lung cancer; metabonomics; RRLC MS, potential biomarkers

Indexed keywords

5 HYDROXYTRYPTOPHAN; ADENOSINE DERIVATIVE; CAFFEIC ACID; CYSTEINE; CYTIDINE; ESTRIOL; ESTRONE; HIPPURIC ACID; INOSINE; ISOLEUCINE; KYNURENIC ACID; PHENYLALANINE; THREONINE; TRYPTOPHAN; TUMOR MARKER; TYROSINE; URIDINE; VALINE; VANILLIC ACID;

AMINO ACID METABOLISM; ARTICLE; ATMOSPHERIC PRESSURE PHOTOIONIZATION; CANCER PATIENT; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC PROCEDURE; ELECTROSPRAY MASS SPECTROMETRY; HUMAN; LUNG CANCER; METABOLITE; PRIORITY JOURNAL; PROTEIN DEGRADATION; STANDARDIZATION; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; URINALYSIS; URINE;

AGED; CASE-CONTROL STUDIES; CHINA; CHROMATOGRAPHY, LIQUID; HUMANS; LUNG NEOPLASMS; METABOLOMICS; MIDDLE AGED; MULTIVARIATE ANALYSIS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TANDEM MASS SPECTROMETRY; TUMOR MARKERS, BIOLOGICAL;

EID: 77955435782     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/pr100265g     Document Type: Article

References (38)

1. Nicholson, J. K.; Lindon, J. C.; Holmes, E. 'Metabonomics': understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data Xenobiotica 1999, 29, 1181-1189
2. Nicholson, J. K.; Wilson, I. D. Opinion: understanding 'global' systems biology: metabonomics and the continuum of metabolism Nat. Rev. Drug Discovery 2003, 2, 668-676
3. Tang, H. R.; Wang, Y. L. Metabolomics-a revolution in progress Prog. Biochem. Biophys. 2006, 33, 401-417
4. Lindon, J. C.; Holmes, E.; Bollard, M. E.; Stanley, E. G.; Nicholson, J. K. Metabonomics technologies and their applications in physiological monitoring, drug safety assessment and disease diagnosis Biomarkers 2004, 9, 1-31
5. Yang, J.; Zhao, X.; Liu, X.; Wang, C.; Gao, P.; Wang, J.; Li, L.; Gu, J.; Yang, S.; Xu, G. High performance liquid chromatography-mass spectrometry for metabonomics: potential biomarkers for acute deterioration of liver function in chronic hepatitis B J. Proteome Res. 2006, 5, 554-561
6. Ramautar, R.; van der Plas, A. A.; Nevedomskaya, E.; Derks, R. J.; Somsen, G. W.; de Jong, G. J.; van Hilten, J. J.; Deelder, A. M.; Mayboroda, O. A. Explorative analysis of urine by capillary electrophoresis-mass spectrometry in chronic patients with complex regional pain syndrome J. Proteome Res. 2009, 8, 5559-5567
7. Sreekumar, A.; Poisson, L. M.; Rajendiran, T. M.; Khan, A. P.; Cao, Q.; Yu, J.; Laxman, B.; Mehra, R.; Lonigro, R. J.; Li, Y.; Nyati, M. K.; Ahsan, A.; Kalyana-Sundaram, S.; Han, B.; Cao, X.; Byun, J.; Omenn, G. S.; Ghosh, D.; Pennathur, S.; Alexander, D. C.; Berger, A.; Shuster, J. R.; Wei, J. T.; Varambally, S.; Beecher, C.; Chinnaiyan, A. M. Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression Nature 2009, 457, 910-914
8. Want, E. J.; Nordström, A.; Morita, H.; Siuzdak, G. From exogenous to endogenous: the inevitable imprint of mass spectrometry in metabolomics J. Proteome Res. 2007, 6, 459-468
9. Dettmer, K.; Aronov, P. A.; Hammock, B. D. Mass spectrometry-based metabolomics Mass Spectrom. Rev. 2007, 26, 51-78
10. Guo, K.; Li, L. Differential 12C-/13C-isotope dansylation labeling and fast liquid chromatography/mass spectrometry for absolute and relative quantification of the metabolome Anal. Chem. 2009, 81, 3919-3932
11. Ogiso, H. Taguchi, Ryo. Reversed-phase LC/MS method for polyphosphoinositide analyses: changes in molecular species levels during epidermal growth factor activation in A431 cells Anal. Chem. 2008, 80, 9226-9232
12. Wilson, I. D.; Plumb, R.; Granger, J.; Major, H.; Williams, R.; Lenz, E. M. HPLC-MS-based methods for the study of metabonomics J. Chromatogr., B: Anal. Technol. Biomed. Life Sci. 2005, 817, 67-76
13. Wilson, I. D.; Nicholson, J. K.; Castro-Perez, J.; Granger, J. H.; Johnson, K. A.; Smith, B. W.; Plumb, R. S. High resolution "ultra performance" liquid chromatography coupled to oa-TOF mass spectrometry as a tool for differential metabolic pathway profiling in functional genomic studies J. Proteome Res. 2005, 4, 591-598
14. Yin, P.; Zhao, X.; Li, Q.; Wang, J.; Li, J.; Xu, G. Metabonomics study of intestinal fistulas based on ultraperformance liquid chromatography coupled with Q-TOF mass spectrometry (UPLC/Q-TOF MS) J. Proteome Res. 2006, 5, 2135-2143
15. Plumb, R. S.; Rainville, P. D.; Potts, W. B.; Johnson, K. A.; Gika, E.; Wilson, I. D. Application of ultra performance liquid chromatography-mass spectrometry to profiling rat and dog bile J. Proteome Res. 2009, 8, 2495-2500
16. Yoshida, T.; Majors, R. E.; Kumagai, H. High-speed analyses using rapid resolution liquid chromatography on 1.8-microm porous particles J. Sep. Sci. 2006, 29, 2421-2432
17. Matuszewski, B. K.; Constanzer, M. L.; Chavez-Eng, C. M. Matrix effect in quantitative LC/MS/MS analyses of biological fluids: a method for determination of finasteride in human plasma at picogram per milliliter concentrations Anal. Chem. 1998, 70, 882-889
18. Mei, H.; Hsieh, Y.; Nardo, C.; Xu, X.; Wang, S.; Ng, K.; Korfmacher, W. A. Investigation of matrix effects in bioanalytical high-performance liquid chromatography/tandem mass spectrometric assays: application to drug discovery Rapid Commun. Mass Spectrom. 2003, 17, 97-103
19. Hsieh, Y.; Merkle, K.; Wang, G.; Brisson, J.-M.; Korfmacher, W. A. High-performance liquid chromatography-atmospheric pressure photoionization/ tandem mass spectrometric analysis for small molecules in plasma Anal. Chem. 2003, 75, 3122-3127 (Pubitemid 36830442)
20. Hanold, K. A.; Fischer, S. M.; Cormia, P. H.; Miller, C. E.; Syage, J. A. Atmospheric pressure photoionization. 1. General properties for LC/MS Anal. Chem. 2004, 76, 2842-2851
21. Nordström, A.; Want, E.; Northen, T.; Lehtiö, J.; Siuzdak, G. Multiple ionization mass spectrometry strategy used to reveal the complexity of metabolomics Anal. Chem. 2008, 80, 421-429
22. Gika, H. G.; Theodoridis, G. A.; Wingate, J. E.; Wilson, I. D. Within-day reproducibility of an HPLC-MS-based method for metabonomic analysis: application to human urine J. Proteome Res. 2007, 6, 3291-3303
23. Katajamaa, M.; Orešič, M. Processing methods for differential analysis of LC/MS profile data BMC Bioinf. 2005, 6, 179
24. Smilde, A. K.; van der Werf, M. J.; Bijlsma, S.; van der Werff-van der Vat, B. J.; Jellema, R. H. Fusion of mass spectrometry-based metabolomics data Anal. Chem. 2005, 77, 6729-6736
25. de la Fuente, A.; Bing, N.; Hoeschele, I.; Mendes, P. Discovery of meaningful associations in genomic data using partial correlation coefficients Bioinformatics 2004, 20, 3565-3574
26. Eriksson, L.; Johansson, E.; Kettaneh-Wold, N.; Trygg, J.; Wikström, C.; Wold, S. Multivariate and Megavariate Data Analysis Part II: Advanced Applications and Method Extensions; Umetrics: Sweden, 2006.
27. Bylesjö, M.; Rantalainen, M.; Cloarec, O.; Nicholson, J. K.; Holmes, E.; Trygg, J. OPLS discriminant analysis: combining the strengths of PLS-DA and SIMCA classification J. Chemometrics 2006, 20, 341-351
28. Eriksson, L.; Johansson, E.; Kettaneh-Wold, N.; Trygg, J.; Wikström, C.; Wold, S. Multivariate and Megavariate Data Analysis Part I: Basic Principles and Applications; Umetrics Academy: Sweden, 2001.
29. Chen, Y.; Zhang, R.; Song, Y.; He, J.; Sun, J.; Bai, J.; An, Z.; Dong, L.; Zhan, Q.; Abliz, Z. RRLC-MS/MS-based metabonomics combined with in-depth analysis of metabolic correlation network: finding potential biomarkers for breast cancer Analyst 2009, 134, 2003-2011
30. Wiklund, S.; Johansson, E.; strolm, L. S.; Mellerowicz, E. J.; Edlund, U.; Shockcor, J. P.; Gottfries, J.; Moritz, T.; Trygg, J. Visualization of GC/TOF-MS-based metabolomics data for identification of biochemically interesting compounds using OPLS class models Anal. Chem. 2008, 80, 115-122
31. Laviano, A.; Cascino, A.; Muscaritoli, M.; Fanfarillo, F.; Rossi Fanelli, F. Tumor-induced changes in host metabolism: a possible role for free tryptophan as a marker of neoplastic disease Adv. Exp. Med. Biol. 2003, 527, 363-366
32. Nijveldt, R. J.; Siroen, M. P.; Teerlink, T.; van Leeuwen, P. A. Elimination of asymmetric dimethylarginine by the kidney and the liver: a link to the development of multiple organ failure J. Nutr. 2004, 134 (10) 2848S-2852S; discussion 2853S
33. Nijveldt, R. J.; Teerlink, T.; van Leeuwen, P. A. The asymmetrical dimethylarginine (ADMA)-multiple organ failure hypothesis Clin. Nutr. 2003, 22, 99-104 (Pubitemid 36193187)
34. Schulze, F.; Vollert, J.; Maas, R.; Müller, R.; Schwedhelm, E.; Müller, C.; Böger, R. H.; Möckel, M. Asymmetric dimethylarginine predicts outcome and time of stay in hospital in patients attending an internal medicine emergency room Clin. Chim. Acta 2009, 401, 20-24
35. Szuba, A.; Chachaj, A.; Wróbel, T.; Dzietczenia, J.; Mazur, G.; Antonowicz-Juchniewicz, J.; Kuliczkowski, K.; Andrzejak, R. Asymmetric dimethylarginine in hematological malignancies: a preliminary study Leuk. Lymphoma 2008, 49, 2316-2320
36. Vinci, E.; Rampello, E.; Zanoli, L.; Oreste, G.; Pistone, G.; Malaguarnera, M. Serum carnitine levels in patients with tumoral cachexia Eur. J. Intern. Med. 2005, 16, 419-423
37. Steiber, A.; Kerner, J.; Hoppel, C. L. Carnitine: a nutritional, biosynthetic, and functional perspective Mol. Aspects Med. 2004, 25, 455-473
38. Frickenschmidt, A.; Frohlich, H.; Bullinger, D.; Zell, A.; Laufer, S.; Gleiter, C. H.; Liebich, H.; Kammerer, B. Metabonomics in cancer diagnosis: mass spectrometry-based profiling of urinary nucleosides from breast cancer patients Biomarkers 2008, 13, 435-449