Naringenin prevents high glucose-induced mitochondria-mediated apoptosis involving AIF, Endo-G and caspases

Apoptosis

Volumn 18, Issue 1, 2013, Pages 9-27

  Kapoor, Radhika ^a   Rizvi, Fatima ^a   Kakkar, Poonam ^a  

^a CSIR INDIAN INSTITUTE OF TOXICOLOGY RESEARCH   (India)

Author keywords

Apoptosis; Apoptosis inducing factor; Glucose toxicity; Mitochondrial dysfunction; Naringenin; Oxidative stress

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; ALAMAR BLUE; APOPTOSIS INDUCING FACTOR; CASPASE; CASPASE 3; CASPASE 9; COPPER ZINC SUPEROXIDE DISMUTASE; CYTOCHROME C; DNA; DYE; ENDONUCLEASE G; GLUCOSE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; MANGANESE SUPEROXIDE DISMUTASE; MESSENGER RNA; NARINGENIN; PHOSPHATIDYLSERINE; PROTEIN BAX; PROTEIN BCL 2; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CELL NUCLEUS; CELL ORGANELLE; CELL POPULATION; CELL VIABILITY; CHROMATIN CONDENSATION; CONTROLLED STUDY; CYTOSOL; DNA DAMAGE; DRUG INHIBITION; GENE EXPRESSION; IN VITRO STUDY; INCUBATION TIME; LIVER CELL; LIVER MITOCHONDRION; MALE; MITOCHONDRIAL MEMBRANE POTENTIAL; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION;

ANIMALS; ANTIOXIDANTS; APOPTOSIS; APOPTOSIS INDUCING FACTOR; CASPASE 3; CASPASE 9; CYTOCHROMES C; ENDODEOXYRIBONUCLEASES; ENZYME ACTIVATION; FLAVANONES; GLUCOSE; HEPATOCYTES; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; OXIDATIVE STRESS; RATS, WISTAR;

RATTUS;

EID: 84872614460     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-012-0781-7     Document Type: Article

References (42)

1. World Health Organization; Media Centre, Diabetes, Facts and Figures, Fact sheet N312 August 2011. http://www.who.int/mediacentre/factsheets/fs312/en/ index.html
2. Sato Y, Feng GG, Huang L, Fan JH, Chang An J, Koji T, Kurokawa S, Fujiwara Y, Toru K, Kondo F, Ishikawa N (2010) Enhanced expression of naofen in kidney of streptozotocin induced diabetic rats: possible correlation to apoptosis of tubular epithelial cells. Clin Exp Nephrol 14:205-212. doi: 10.1007/s10157-010-0276-1
3. Mokini Z, Marcovecchio ML, Chiarelli F (2010) Molecular pathology of oxidative stress in diabetic angiopathy: role of mitochondrial and cellular pathways. Diabetes Res Clin Pract 87:313-321. doi: 10.1016/j.diabres.2009.11.018
4. Choi SW, Benzie IFF, Ma SW, Strain JJ, Hannigan BM (2008) Acute hyperglycemia and oxidative stress: direct cause and effect? Free Radic Biol Med 44:1217-1231. doi: 10.1016/j.freeradbiomed.2007.12.005
5. Cusi K (2009) Nonalcoholic fatty liver disease in type 2 diabetes mellitus. Curr Opin Endocrinol Diabetes Obes 16:141-149. doi: 10.1097/med.0b013e3283293015
6. Dey A, Swaminathan K (2010) Hyperglycemia-induced mitochondrial alterations in liver. Life Sci 87:197-214. doi: 10.1016/j.lfs.2010.06.007
7. Kakkar P, Singh BK (2007) Mitochondria: a hub of redox activities and cellular distress control. Mol Cell Biochem 305:235-253. doi: 10.1007/s11010-007-9520-8
8. Palmeira CM, Rolo AP, Berthiaume J, Bjork JA, Wallace KB (2007) Hyperglycemia decreases mitochondrial function: the regulatory role of mitochondrial biogenesis. Toxicol Appl Pharmacol 225:214-220. doi: 10.1016/j.taap.2007.07.015
9. Malfitano C, Tatiana C, Loureiro A, Rodrigues B, Sirvente R, Salemi VMC, Rabechi NB, Lacchini S, Curi R, Irigoyen MCC (2010) Hyperglycemia protects the heart after myocardial infarction: aspects of programmed cell survival and cell death. Eur J Heart Fail 12:659-667. doi: 10.1093/eurjhf/hfq053
10. Chandrasekaran K, Swaminathan K, Chatterjee S, Dey A (2010) Apoptosis in HepG2 cells exposed to high glucose. Toxicol In Vitro 24:387-396. doi: 10.1016/j.tiv.2009.10.020
11. Leal EC, Aveleira CA, Castilho AF, Serra AM, Baptista FI, Hosoya KI, Forrester JV, Ambrosio AF (2009) High glucose and oxidative/nitrosative stress conditions induce apoptosis in retinal endothelial cells by a caspase-independent pathway. Exp Eye Res 88:983-991. doi: 10.1016/j.exer.2008. 12.010
12. Chen Y, Lewis W, Diwan A, Cheng EHY, Matkovich SJ, Dorn GW (2010) Dual autonomous mitochondrial cell death pathways are activated by Nix/BNip3L and induce cardiomyopathy. Proc Natl Acad Sci 20:9035-9042. doi: 10.1073/pnas.0914013107
13. Frances DE, Ronco MT, Monti JA, Ingaramo PI, Pisani GB, Parody JP, Pellegrino JM, Sanz PM, Carrillo MC, Carnovale CE (2010) Hyperglycemia induces apoptosis in rat liver through the increase of hydroxyl radical: new insights into the insulin effect. J Endocrinol 205:187-200. doi: 10.1677/JOE-09-0462
14. Purushotam A, Tian M, Belury MA (2009) The citrus fruits flavanoids naringenin suppresses hepatic glucose production from Fao hepatoma cells. Mol Nutr Food Res 53:300-307. doi: 10.1002/mnfr.200700514
15. Sohn E, Kim J, Kim CS, Kim YS, Jang DS, Kim JS (2010) Extract of the aerial parts of Aster koraiensis reduced development of diabetic nephropathy via anti-apoptosis of podocytes in streptozotocin-induced diabetic rats. Biochem Biophys Res Commun 391:733-738. doi: 10.1016/j.bbrc.2009.11.129
16. Rajadurai M, Stanely P, Prince M (2007) Preventive effect of naringenin on isoproterenol-induced cardiotoxicity in Wistar rats: an in vivo and in vitro study. Toxicology 232:216. doi: 10.1016/j.tox.2007.01.006
17. Seglen PO (1976) Preparation of isolated rat liver cells. Methods Cell Biol 19:187-191
18. Chu HL, Chien JC, Duh PD (2011)) Protective effect of Cordyceps militaris against high glucose-induced oxidative stress in human umbilical vein endothelial cells. Food Chem 129:871-876. doi: 10.1016/j.foodchem.2011.05.037
19. Leinninger GM, Russell JW, van Golen CM, Berent A, Feldman EL (2004) Insulin-like growth factor-I regulates glucose-induced mitochondrial depolarization and apoptosis in human neuroblastoma. Cell Death Differ 11(8):885-896. doi: 10.1038/sj.cdd.4401429
20. Russell JW, Golovoy D, Vincent AM, Mahendru P, Olzmann JA, Mentzer A, Feldman EL (2002) High glucose-induced oxidative stress and mitochondrial dysfunction in neurons. FASEB J 16(13):1738-1748. doi: 10.1096/fj.01-1027
21. Varma S, Lal BK, Zheng R, Breslin JW, Saito S, Pappas PJ, Hobson RW II, Durán WN (2005) Hyperglycemia alters PI3K and Akt. Am J Physiol Heart Circ Physiol 289(4):H1744-1751. doi: 10.1152
22. Hornick T, Aron D (2008) Preventing and managing diabetic complications in elderly patients. Clevel Clin J Med 75:153-158. doi: 10.3949/ccjm.75.2.153
23. Cloherty JP, Eichenwald EC, Hansen AR, Stark AR (2012) Manual of Neonatal Care. Lippinncott Williams & Wilkins
24. Mosmonn T (1983) Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 65:55-63. doi: 10.1016/0022-1759(83)90303-4
25. Kakkar P, Vishwanathan PND (1984) A modified spectrophotometric assay of superoxide dismutase. Indian J Biochem Biophys 21:130-132
26. Aebi H (1984) Catalase Invitro. Methods Enzymol 113:121-126
27. Dringen R, Hamprecht B (1996) Glutathione content as an indicator for the presence of metabolic pathways of amino acids in astroglial cultures. J Neurochem 67:1375-1382. doi: 10.1046/j.1471-4159.1996.67041375.x
28. Paglia DE, Valentine WN (1967) Studies on qualitative and quantitative characterization of erythrocytes Glutathione Peroxidase. J Lab Clin Med 70:158-169
29. Zhang J, Liu Y, Yang HW, Xu HY, Meng Y (2008) Molecular mechanism of beta cell apoptosis induced by p58 in high glucose medium. Arch Pharm Res 31:357-363
30. Tripathi M, Singh BK, Mishra C, Raisuddin S, Kakkar P (2010) Involvement of mitochondria-mediated pathways in hepatoprotection conferred by Fumaria parviflora Lam. extract against nimesulide-induced apoptosis in vitro. Toxicol in Vitro 24:495-508. doi: 10.1016/j.tiv.2009.09.011
31. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ (1951) Protein measurement with the Folin-phenol reagent. J Biol Chem 193:265-275
32. Rodrigues CMP, Sola S, Nani Z, Castro RE, Ribeiro PS, Walter C, Low C, Steer CJ (2003) Tauroursodeoxycholic acid reduces apoptosis and protects against neurological injury after acute hemorrhagic stroke in rats. Proc Natl Acad Sci 100:6087-6092. doi: 10.1073/pnas.1031632100
33. Nigam N, George J, Srivastava S, Roy P, Bhui K, Singh M, Shukla Y (2010) Induction of apoptosis by [6]-gingerol associated with the modulation of p53 and involvement of mitochondrial signaling pathway in B[a]P-induced mouse skin tumorigenesis. Cancer Chemother Pharmacol 65:687-696. doi: 10.1007/s00280-009- 1074-x
34. Thurau M, Marquardt G, Laurent NG, Weinlander K, Naschberger E, Jochmann R, Alkharsah KR, Schulz TF, Thome M, Neipel F, Sturzl M (2009) Viral inhibitor of apoptosis vFLIP/K13 protects endothelial cells against superoxide-induced cell death. J Virol 83:598-611. doi: 10.1128/jvi.00629-08
35. Kapoor R, Srivastava S, Kakkar P (2009) Bacopa monnieri modulates antioxidant responses in brain and kidney of diabetic rats. Environ Toxicol Pharmacol 27:62-69. doi: 10.1016/j.etap.2008.08.007
36. Pang J, Gong H, Xi C, Fan W, Dai Y, Zhang TM (2011) Poly (ADP-ribose) polymerase 1 is involved in glucose toxicity through SIRT1 modulation in HepG2 hepatocytes. China J Cell Biochem 112:299-306
37. Meng L, Cui L (2008) Inhibitory effects of crocetin on high glucose-induced apoptosis in cultured human umbilical vein endothelial cells and its mechanism. Arch Pharm Res 31:357-363. doi: 10.1007/s12272-001-1164-y
38. Sutovsky MP, Latham KE, Han Z, Vassena R, Chi MMY, Potireddy S, Sutovsky M, Kelle H (2008) Role of glucose in cloned mouse embryo development. Am J Physiol Endocrinol Metab 295:798-809. doi: 10.1152/ajpendo.00683.2007
39. Bell DS, Allbright E (2007) The multifaceted associations of hepatobiliary disease and diabetes. Endocr Pract 13:300-312
40. Velagapudi C, Bhandari BS, Simone S, Abboud HE, Habib SL (2011) The Tuberin/mTOR pathway promotes apoptosis of tubular epithelial cells in diabetes. J Am Soc Nephrol 22:262-273. doi: 10.1681/asn.2010040352
41. Mustapha NM, Tarr JM, Kohner EM, Chibber R (2010) NADPH oxidase versus mitochondria-derived ROS in glucose-induced apoptosis of pericytes in early Diabetic retinopathy. J Ophthalmol. doi: 10.1155/2010/746978
42. Fei AL, Roy S (2009) High glucose-induced downregulation of connexin 43 expression promotes apoptosis in microvascular endothelial cells. Invest Ophthalmol Vis Sci 50:1400-1407. doi: 10.1167/iovs.07-1519