Possible implications of acid-sensing ion channels in ischemia-induced retinal injury in rats

Japanese Journal of Ophthalmology

Volumn 57, Issue 1, 2013, Pages 120-125

  Miyake, Takatomo ^a   Nishiwaki, Akiko ^a   Yasukawa, Tsutomu ^a   Ugawa, Shinya ^a   Shimada, Shoichi ^b   Ogura, Yuichiro ^a  

^a NAGOYA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICAL SCIENCES   (Japan)

^b OSAKA UNIVERSITY   (Japan)

Author keywords

Acid sensing ion channel (ASIC); Amiloride; Neuroprotection; Retinal ischemia

Indexed keywords

ACID SENSING ION CHANNEL; AMILORIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFICACY; ELECTRORETINOGRAM; HISTOLOGY; MALE; NERVE CELL; NERVE DEGENERATION; NEUROPROTECTION; NONHUMAN; OPTIC NERVE; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RETINA DEGENERATION; RETINA INJURY; RETINA ISCHEMIA; TREATMENT RESPONSE;

ACID SENSING ION CHANNELS; ANIMALS; DISEASE MODELS, ANIMAL; ELECTRORETINOGRAPHY; ISCHEMIA; MALE; RATS; RATS, LONG-EVANS; REPERFUSION INJURY; RETINA; RETINAL DISEASES; RETINAL VESSELS;

EID: 84872597824     PISSN: 00215155     EISSN: 16132246     Source Type: Journal    
DOI: 10.1007/s10384-012-0213-9     Document Type: Article

References (40)

1. Osborne NN, Casson RJ, Wood JP, Chidlow G, Graham M, Melena J. Retinal ischemia: mechanisms of damage and potential therapeutic strategies. Prog Retin Eye Res. 2004;93:91-147.
2. Tsujikawa A, Ogura Y, Hiroshiba N, Miyamoto K, Kiryu J, Honda Y. In vivo evaluation of leukocyte dynamics in retinal ischemia reperfusion injury. Invest Ophthalmol Vis Sci. 1998;39:793-800.
3. Nicholls D, Attell D. The release and uptake of excitatory amino acids. Trends Pharmacol Sci. 1990;11:462-7.
4. Choi DW. Calcium-mediated neurotoxicity: relationship to specific channel types and role in ischemic damage. Trends Neurosci. 1988;11:465-9.
5. Rothman SM, Olney JW. Excitotoxicity and the NMDA receptor - still lethal after eight years. Trends Neurosci. 1995;18:57-8.
6. Mori H, Mishina M. Structure and function of the NMDA receptor channel. Neuropharmacology. 1995;34:1219-37.
7. Sucher NJ, Lipton SA, Dreyer EB. Molecular basis of glutamate toxicity in retinal ganglion cells. Vis Res. 1997;37:3483-93.
8. Tymianski C. Cytosolic calcium concentrations and cell death in vitro. Adv Neurol. 1996;71:85-105.
9. Lee JM, Zipfel GJ, Choi DW. The changing landscape of ischaemic brain injury mechanisms. Nature. 1999;399:A7-14.
10. Wahlgren NG, Ahmed N. Neuroprotection in cerebral ischaemia: facts and fancies - the need for new approaches. Cerebrovasc Dis. 2004;17:153-66.
11. Lombardi G, Moroni F, Moroni F. Glutamate receptor antagonists protect against ischemia-induced retinal damage. Eur J Pharmacol. 1994;271:489-95.
12. Rehncrona S. Brain acidosis. Ann Emerg Med. 1985;14:770-6.
13. Waldmann R, Champigny G, Bassilana F, Heurteaux C, Lazdunski M. A proton-gated cation channel involved in acid-sensing. Nature. 1997;386:173-7.
14. Krishtal O. The ASICs: signaling molecules? Modulators? Trends Neurosci. 2003;26:477-83.
15. Ugawa S, Ueda T, Ishida Y, Nishigaki M, Shibata Y, Shimada S. Amiloride-blockable acid sensing ion channels are leading acid sensors expressed in human nociceptors. J Clin Invest. 2002;110:1185-90.
16. Kellenberger S, Schild L. Epithelial sodium channel/degenerin family of ion channels: a variety of function for a shared structure. Physiol Rev. 2002;82:735-67.
17. + channel MDEG1. J Biol Chem. 1998;25:15418-22.
18. 2+-permeable ion channels and ischemic brain injury. J Membr Biol. 2006;209:59-68.
19. Xiong ZG, Zhu XM, Chu XP, Minami M, Hey J, Wei WL, et al. Neuroprotection in ischemia: blocking calcium-permeable acid-sensing ion channels. Cell. 2004;118:687-98.
20. Hu W, Chen FH, Yuan FL, Zhang TY, Wu FR, Rong C, et al. Blockade of acid-sensing ion channels protects articular chondrocytes from acid-induced apoptotic injury. Inflamm Res. 2012;61:327-35.
21. Duan B, Wang YZ, Yang T, Chu XP, Yu Y, Huang Y, et al. Extracellular spermine exacerbates ischemic neuronal injury through sensitization of ASIC1a channels to extracellular acidosis. J Neurosci. 2011;31:2101-12.
22. Brockway LM, Zhou ZH, Bubien JK, Jovov B, Benos DJ, Keyser KT. Rabbit retinal neurons and glia express a variety of EnaC/DEG subunits. Am J Physiol Cell Physiol. 2002;283:C126-34.
23. Lilley S, LeTissier P, Robbins J. The discovery and characterization of a proton-gated sodium current in rat retinal ganglion cells. J Neurosci. 2004;24:1013-22.
24. Ettaiche M, Deval E, Cougnon M, Lazdunski M, Voilley N. Silencing acid-sensing ion channel 1a alters cone-mediated retinal function. J Neurosci. 2006;26:5800-9.
25. Ettaiche M, Guy N, Hofman P, Lazdunski M, Waldmann R. Acid-sensing ion channel 2 is important for retinal function and protects against light-induced retinal degeneration. J Neurosci. 2004;24:1005-12.
26. Mizuno S, Nishiwaki A, Morita H, Miyake T, Ogura Y. Effect of periocular administration of triamcinolone acetonide on leukocyte-endothelium interactions in the ischemic retina. Invest Ophthalmol Vis Sci. 2007;48:2831-6.
27. Berkowitz BA, Lukaszew RA, Mullins CM, Penn JS. Impaired hyaloidal circulation function and uncoordinated ocular growth patters in experimental retinopathy of prematurity. Invest Ophthalmol Vis Sci. 1998;39:391-6.
28. Hughes WF. Quantitation of ischemic damage in the rat retina. Exp Eye Res. 1991;53:573-82.
29. Machida S, Kondo M, Jamison JA, Khan NW, Kononen LT, Sugawara T, et al. P23H rhodopsin transgenic rat: correlation of retinal function with histopathology. Invest Ophthalmol Vis Sci. 2000;41:3200-9.
30. Ettaiche M, Deval E, Pagnotta S, Lazdunski M, Lingueglia E. Acid-sensing ion channel 3 in retinal function and survival. Invest Ophthalmol Vis Sci. 2009;50:2417-26.
31. Tan J, Ye X, Xu Y, Wang H, Sheng M, Wang F. Acid-sensing ion channel 1a is involved in retinal ganglion cell death induced by hypoxia. Mol Vis. 2011;17:3300-8.
32. Brockway LM, Benos DJ, Keyser KT, Kraft TW. Blockade of amiloride-sensitive sodium channels alters multiple components of the mammalian electroretinogram. Vis Neurosci. 2005;22:143-51.
33. Gao J, Duan B, Wang DG, Deng XH, Zhang GY, Xu L, et al. Coupling between NMDA receptor and acid-sensing ion channel contributes to ischemic neuronal death. Neuron. 2005;48:635-46.
34. Nakazawa T, Watanabe M, Kudo H, Nishida K, Tamai M. Susceptibility to N-methyl-d-aspartate toxicity in morphological and functional types of cat retinal ganglion cells. Jpn J Ophthalmol. 2010;54:156-62.
35. Tan J, Ye X, Xu Y, Wang H, Sheng M, Wang F. Acid-sensing ion channel 1a is involved in retinal ganglion cell death induced by hypoxia. Mol Vis. 2011;17:3300-8.
36. Ogishima H, Nakamura S, Nakanishi T, Imai S, Kakino M, Ishizuka F, et al. Ligation of the pterygopalatine and external carotid arteries induces ischemic damage in the murine retina. Invest Ophthalmol Vis Sci. 2011;52:9710-20.
37. Mizote M, Hirooka K, Fukuda K, Nakamura T, Itano T, Shiraga F. d-allose as ischemic retina injury inhibitor during rabbit vitrectomy. Jpn J Ophthalmol. 2011;55:294-300.
38. Tang CM, Presser F, Morad M. Amiloride selectively blocks the low threshold (T) calcium channel. Science. 1988;240:213-5.
39. Palandoken H, By K, Hegde M, Harley WR, Gorin FA, Nantz MH. Amiloride peptide conjugates: prodrugs for sodium-proton exchange inhibition. J Pharmacol Exp Ther. 2005;312:961-7.
40. + channel is made of three homologous subunits. Nature. 1994;367:463-7.