A novel interface for hybrid mock circulations to evaluate ventricular assist devices

IEEE Transactions on Biomedical Engineering

Volumn 60, Issue 2, 2013, Pages 507-516

  Ochsner, Gregor ^a   Amacher, Raffael ^a   Amstutz, Alois ^a   Plass, André ^b   Daners, Marianne Schmid ^a   Tevaearai, Hendrik ^c   Vandenberghe, Stijn ^d   Wilhelm, Markus J ^b   Guzzella, Lino ^a  

^a ETH ZURICH   (Switzerland)

^b UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^c UNIVERSITY OF BERN   (Switzerland)

^d UNIVERSITY OF BERN   (Switzerland)

Author keywords

Feedback control; hardware in the loop; mechanical circulatory support (MCS); mock circulation; ventricular assist device (VAD)

Indexed keywords

BLOOD PUMP; HARD-WARE-IN-THE-LOOP; HUMAN BLOODS; MECHANICAL CIRCULATORY SUPPORT; MOCK CIRCULATION; PRESSURE VALUES; REAL TIME; VENTRICULAR ASSIST DEVICE;

CARDIOVASCULAR SYSTEM; FEEDBACK CONTROL; FLOW RATE; HARDWARE; SYNTHETIC APERTURES;

NUMERICAL MODELS;

ARTICLE; BLOOD FLOW VELOCITY; BLOOD PRESSURE; BLOOD PUMP; BLOOD VOLUME; CIRCULATION; COMPUTER; COMPUTER PROGRAM; HUMAN; MODEL; VENTRICULAR ASSIST DEVICE;

COMPUTER SIMULATION; EQUIPMENT DESIGN; FEEDBACK; HEART-ASSIST DEVICES; HUMANS; MODELS, CARDIOVASCULAR; PRESSURE; SIGNAL PROCESSING, COMPUTER-ASSISTED;

EID: 84872559364     PISSN: 00189294     EISSN: 15582531     Source Type: Journal    
DOI: 10.1109/TBME.2012.2230000     Document Type: Article

References (29)

1. D. Timms, "A review of clinical ventricular assist devices," Med. Eng. Phys., vol. 33, pp. 1041-1047, 2011.
2. P. Verdonck, A. Kleveln, R. Verhoeven, B. Angelsen, and J. Vandenbogaerde, "Computer-controlled in vitro model of the human left heart," Med. Biol. Eng. Comput., vol. 30, pp. 656-659, 1992. (Pubitemid 23009093)
3. P. Segers, F. Dubois, D. D.Wachter, and P. Verdonck, "Role and relevancy of a cardiovascular simulator," Cardiovasular Eng., vol. 3, pp. 48-56, 1998. (Pubitemid 28224702)
4. O. Dur, M. Lara, D. Arnold, S. Vandenberghe, B. B. Keller, C. DeGroff, and K. Pekkan, "Pulsatile in vitro simulation of the pediatric univentricular circulation for evaluation of cardiopulmonary assist scenarios," Artif. Organs, vol. 33, pp. 967-976, 2009.
5. D. L. Timms, S. D.Gregory, N. A. Greatrex,M. J. Pearcy, J. F. Fraser, and U. Steinseifer, "A compact mock circulation loop for the in vitro testing of cardiovascular devices," Artif. Organs, vol. 35, pp. 384-391, 2010.
6. S. Vandenberghe, F. Shu, D. K. Arnold, and J. F. Antaki, "A simple, economical, and effective portable paediatric mock circulatory system," Proc. Inst. Mech. Eng. H., 2011, vol. 225, pp. 648-656.
7. G. Ferrari, C. De Lazzari, R. Mimmo, G. Tosti, D. Ambrosi, and K. Gorczynska, "A computer controlled mock circulatory system for mono- and biventricular assist device testing," Int. J. Artif.Organs, vol. 21, pp. 26-36, 1998. (Pubitemid 28140767)
8. L. A. Baloa, J. R. Boston, and J. F. Antaki, "Elastance-based control of a mock circulatory system," Ann. Biomed. Eng., vol. 29, pp. 244-251, 2001. (Pubitemid 32380953)
9. M. Kozarski, G. Ferrari, F. Clemente, K. Groczynska, C. D. Lazzari, M. Darowski, R. Mimmo, G. Tosti, and M. Guaragno, "A hybrid mock circulatory system: Development and testing of an electro-hydraulic impedance simulator," Int. J. Artif. Organs, vol. 26, pp. 53-63, 2003. (Pubitemid 36896250)
10. M. Loh and Y.-C. Yu, "Feedback control design for an elastance-based mock circulatory system," in Proc. Amer. Contr. Conf., 2004, pp. 1639- 1644.
11. M. Vaes, M. Rutten, R. van de Molengraft, and F. van de Vosse, "Leftventricular assist device evaluation with a model-controlled mock circulation," presented at the ASME Summer Bioeng. Conf., Keystone, CO, 2007.
12. F. M. Colacino, F. Moscato, F. Piedimonte, G. A. Danieli, S. Nicosia, and M. Arabia, "A modified elastance model to control mock ventricles in real-time: Numerical and experimental validation," Asaio J., vol. 54, pp. 563-573, 2008.
13. K.-W. Gwak, B. E. Paden, J. F. Antaki, and I.-S. Ahn, "Experimental verification of the feasibility of the cardiovascular impedance simulator," IEEE Trans. Biomed. Eng., vol. 57, no. 5, pp. 1176-1183, May 2010.
14. Y. Yokoyama, O. Kawaguchi, T. Shinshi, U. Steinseifer, and S. Takatani, "A new pulse duplicator with a passive fill ventricle for analysis of cardiac dynamics," J. Artif. Organs, vol. 13, pp. 189-196, 2010.
15. M. Pillon, H. Duffour, and M. Jufer, "In vitro experiments: Circulatory assist device interaction with a virtual cardiovascular system," in Proc. IEEE-EMBS 14th Ann. Int. Conf. Eng. Med. Bio. Soc., Oct./Nov. 1992, vol. 2, pp. 740-741.
16. F. M. Colacino, M. Arabia, G. A. Danieli, F. Moscato, S. Nicosia, F. Piedimonte, P. Valigi, and S. Pagnottelli, "Hybrid test bench for evaluation of any device related to mechanical cardiac assistance," Int. J. Artif. Organs, vol. 28, pp. 817-826, 2005. (Pubitemid 41535725)
17. G. Ferrari, M. Kozarski, C. De Lazzari, K. Gorczynska, G. Tosti, and M. Darowski, "Development of a hybrid (numerical-hydraulic) circulatory model: Prototype testing and its response to IABP assistance," Int. J. Artif. Organs, vol. 28, pp. 750-759, 2005. (Pubitemid 41167276)
18. F. Moscato, G. A. Danieli, and H. Schima, "Dynamic modeling and identification of an axial flow ventricular assist device," Int. J. Artif. Organs, vol. 32, pp. 336-343, 2009.
19. F. M. Colacino, F. Moscato, F. Piedimonte, M. Arabia, and G. A. Danieli, "Left ventricle load impedance control by apical VAD can help heart recovery and patient perfusion: A numerical study," Asaio J., vol. 53, pp. 263-277, 2007. (Pubitemid 46795284)
20. L. Guzzella, Analysis and Synthesis of Single-Input Single-Output Control Systems. Zurich, Switzerland: Vdf Hochschulverlag AG, 2011.
21. H. K. Khalil, Nonlinear Systems. Englewood Cliffs, NJ: Prentice-Hall, 1996.
22. S. Choi, J. F.Antaki, J. R. Boston, andD. Thomas, "Asensorless approach to control of a turbodynamic left ventricular assist system," IEEE Trans. Control Syst. Technol., vol. 9, no. 3, pp. 473-482, May 2001. (Pubitemid 32486998)
23. F. Moscato, M. Vollkron, H. Bergmeister, G. Wieselthaler, E. Leonard, and H. Schima, "Left ventricular pressure-volume loop analysis during continuous cardiac assist in acute animal trials," Artif. Organs, vol. 31, pp. 369-376, 2007. (Pubitemid 46669026)
24. A. L. Ferreira, Y. Wang, J. Gorcsan, and J. F. Antaki, "Assessment of cardiac function during mechanical circulatory support: The quest for a suitable clinical index," in Proc. IEEE 33rd Annu. Int. Conf. Eng. Med. Bio. Soc., Aug./Sep. 2011, pp. 223-226.
25. D. Morley, K. Litwak, P. Ferber, P. Spence, R. Dowling, B. Meyns, B. Griffith, and D. Burkhoff, "Hemodynamic effects of partial ventricular support in chronic heart failure: Results of simulation validated with in vivo data," J. Thorac. Cardiov. Surg., vol. 133, pp. 21-28, 2007.
26. H. Schima,W. Trubel, A. Moritz, G.Wieselthaler, H. G. Stohr, H. Thoma, U. Losert, and E.Wolner, "Noninvasivemonitoring of rotary blood pumps: Necessity, possibilities, and limitations," Artif. Organs, vol. 16, pp. 195- 202, 1992.
27. P. Naiyanetr, F. Moscato, M. Vollkron, D. Zimpfer, G. Wieselthaler, and H. Schima, "Continuous assessment of cardiac function during rotary blood pump support: A contractility index derived from pump flow," J. Heart Lung Transplant., vol. 29, pp. 37-44, 2010.
28. G. A. Giridharan, G. M. Pantalos, K. J. Gillars, S. C. Koenig, and S. Mikhail, "Physiologic control of rotary blood pumps:An in vitro study," Asaio J., vol. 50, pp. 403-409, 2004. (Pubitemid 39237947)
29. S. Skogestad and I. Postlethwaite, Multivariable Feedback Control. New York: Wiley, 2005.