A computer controlled mock circulatory system for mono- and biventricular assist device testing

International Journal of Artificial Organs

Volumn 21, Issue 1, 1998, Pages 26-36

  Ferrari, G ^a,c   De Lazzari, C ^a   Mimmo, R ^a   Tosti, G ^a   Ambrosi, D ^a   Gorczynska, K ^b  

^a INSTITUTE OF BIOMEDICAL TECHNOLOGIES   (Italy)

^b INSTITUTE OF BIOCYBERNETICS AND BIOMEDICAL ENGINEERING   (Poland)

^c CNR   (Italy)

Author keywords

Arterial elastance; Cardiovascular models; Heart assist device; In vitro; Ventricular elastance

Indexed keywords

FIBER OPTIC SENSORS; LEFT VENTRICULAR ASSIST DEVICES;

ARTERIAL ELASTANCE; ASSIST DEVICE; CARDIOVASCULAR MODELLING; CLINICAL USE; DEVICE TESTING; ELASTANCE; HEART ASSIST DEVICE; IN-VITRO; MOCK CIRCULATORY SYSTEMS; VENTRICULAR ELASTANCE;

HEART;

ARTERIAL PRESSURE; ARTICLE; ASSISTED CIRCULATION; CARDIOPULMONARY HEMODYNAMICS; CARDIOVASCULAR SYSTEM; COMPUTER MODEL; ENERGY TRANSFER; HEART FUNCTION TEST; HEART VENTRICLE; NONHUMAN; OXYGEN CONSUMPTION; PULSATILE FLOW; STARLING LAW; SYSTEMIC CIRCULATION;

EID: 0031937479     PISSN: 03913988     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (22)

1. Donovan FM jr Design of a hydraulic analog of the circulatory system for evaluating artificial hearts. Biomaterials Medical Devices Artificial Organs 1975; 3: 439-49.
2. Rosenberg G, Phillips WM, Landis DL, Pierce WS. Design and evaluation of the Pennsylvania State University mock circulatory system. ASAIO J 1981; 4: 41-9.
3. Arabia M, Akutsu T. A new test circulatory system for research in cardiovascular engineering. Ann Biomed Eng 1984; 12: 29-48.
4. Swanson WM, Clark RE. A simple cardiovascular system simulator: design and performance. J Bioeng 1977; 1: 135-45.
5. Bowles CT, Shah SS, Nishimura K, et al. Development of mock circulation models for the assessment of counter pulsation systems. Cardiovasc Res 1991; 11: 901-8.
6. Schima H, Baumgartner H, Spitaler F, Kuhn P, Wolner E. A modular mock circulation for hydromechanical studies on valves, stenoses, vascular grafts and cardiac assist devices, Int J Artif Organs 1992; 15(7): 417-21.
7. Reul H. In vitro evaluation of artificial heart valves. In: Ghista DN, Van Vollenhoven E, Yang WJ, Reaul H, Bleifeld W eds. Advances in cardiovascular Physics. Cardiovascular engineering. Part IV: prostheses, assist and artificial organs. Basel: Karger 1983; 5: 16-30.
8. Knierbein B, Reul H, Eilers R, Lange M, Kaufmann R, Rau C. Compact mock loops of the systemic and pulmonary circulation for blood pump testing, Int J Artif Organs 1992; 15: 40-8.
9. Ferrari G, Górczynska K, De Lazzari C, et al. In vitro testing of a left ventricular assist device: study of the effect of its control strategy on energetic relationships inside the left ventricle. Technol Health Care 1996; 3: 231-9.
10. Ferrari G, Mimmo R, Tosti G, Górczynska K, Grodzicki K. A new hydraulic simulator of the circulatory system. Some experimental results in reproducing a physiological and a pathological state. Biocybernetics and Biomedical Engineering 1987: 87-103.
11. Woodard JC, Rock SM, Portner PM. A sophisticated electromechanical ventricular simulator for ventricular assist system testing. ASAIO Trans 1991; 37: M210-11.
12. Ferrari G, De Lazzari C, Mimmo R, Tosti G, Ambrosi D. A mock circulatory system for in vitro reproduction of the left ventricle, the arterial tree and their interaction with a left ventricle assist device. J Med Eng Technol 1994; 18: 87-95.
13. Guyton AC, Jones CE, Coleman TG. Circulatory physiology: cardiac output and its regulation. Philadelphia: Saunders, 1973.
14. Sagawa K, Maughan L, Suga J, Sunagawa K. Cardiac contraction and the Pressure-Volume Relationship. New York: Oxford University Press, 1988.
15. Westerhof N, Sipkema P, Elzinga G, Murgo JP, Giolma JP. Arterial Impedance. In: Hwang NHC, Gross DR and Patel DJ eds. Quantitative Cardiovascular Studies. Baltimore: University Park Press, 1979; 111-50.
16. Westerhof N, Elzinga G, Sipkema P. An artificial arterial system for pumping hearts. J Appl Physiol 1971; 31: 776-81.
17. van den Horn CJ, Westerhof N, Elzinga G. Interaction of heart and arterial system. Ann Biomed Eng 1984; 12: 151-62.
18. Piene H. Impedance matching between ventricle and load. Ann Biomedl Eng 1984; 12: 191-207.
19. Ferrari G, De Lazzari C, Mimmo R, Tosti G, Ambrosi D. A modular numerical model of the cardiovascular system for studying and training in the field of cardiovascular physiopathology. J Biomed Eng 1992; 14: 91-107.
20. Gilbert JC, Glantz SA. Determinants of left ventricular filling and of the diastolic pressure-volume relation. Circ Res 1989; 64: 827-52.
21. Ferrari G, Górczynska K, De Lazzari C, et al. In vitro testing of a left ventricular assist device: study of the effect of its control strategy on energetic relationships inside the left ventricle. Technol Health Care 1996; 3: 231-9.
22. Takano H, Glantz SA. Left ventricular contractility predicts how the end-diastolic pressure-volume relation shifts during pacing-induced ischemia in dogs. Circulation 1995; 91: 2423-34.