Stabilization of the Skeletal Muscle Ryanodine Receptor Ion Channel-FKBP12 Complex by the 1,4-Benzothiazepine Derivative S107

PLoS ONE

Volumn 8, Issue 1, 2013, Pages

  Mei, Yingwu ^a   Xu, Le ^a   Kramer, Henning F ^b   Tomberlin, Ginger H ^b   Townsend, Claire ^b   Meissner, Gerhard ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b GLAXOSMITHKLINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2,3,4,5 TETRAHYDRO 7 METHOXY 4 METHYL 1,4 BENZOTHIAZEPINE; 4 [3 (4 BENZYL 1 PIPERIDINYL)PROPIONYL] 2,3,4,5 TETRAHYDRO 7 METHOXY 1,4 BENZOTHIAZEPINE; BENZOTHIAZEPINE DERIVATIVE; CALCIUM; FK 506 BINDING PROTEIN; GLUTATHIONE; ION CHANNEL; RYANODINE; RYANODINE RECEPTOR 1;

ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BINDING SITE; CALCIUM TRANSPORT; DRUG ACTIVITY; DRUG PROTEIN BINDING; MUSCLE CONTRACTION; MUSCLE FIBRIL; MUSCLE FUNCTION; NONHUMAN; OXIDATION REDUCTION STATE; RABBIT; SARCOPLASMIC RETICULUM; SKELETAL MUSCLE; TISSUE HOMOGENATE;

ANIMALS; BINDING, COMPETITIVE; CALCIUM; GLUTATHIONE; IMMUNOBLOTTING; KINETICS; LIPID BILAYERS; MUSCLE, SKELETAL; NITROSO COMPOUNDS; PROTEIN BINDING; PROTEIN STABILITY; RABBITS; RYANODINE; RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL; SARCOPLASMIC RETICULUM; TACROLIMUS; TACROLIMUS BINDING PROTEIN 1A; THIAZEPINES; TRITIUM;

EID: 84872513964     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0054208     Document Type: Article

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