A PKS/NRPS/FAS Hybrid Gene Cluster from Serratia plymuthica RVH1 Encoding the Biosynthesis of Three Broad Spectrum, Zeamine-Related Antibiotics

PLoS ONE

Volumn 8, Issue 1, 2013, Pages

  Masschelein, Joleen ^a   Mattheus, Wesley ^a   Gao, Ling Jie ^a   Moons, Pieter ^a,c   van Houdt, Rob ^a,d   Uytterhoeven, Birgit ^a   Lamberigts, Chris ^a   Lescrinier, Eveline ^b   Rozenski, Jef ^b   Herdewijn, Piet ^a,b   Aertsen, Abram ^a   Michiels, Chris ^a   Lavigne, Rob ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

^c UNIVERSITY OF ANTWERP   (Belgium)

^d BELGIAN NUCLEAR RESEARCH CENTRE   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; POLYKETIDE; POLYUNSATURATED FATTY ACID; SERRATIA PLYMUTHICA RVH1; UNCLASSIFIED DRUG; ZEAMINE; ZEAMINE 1; ZEAMINE II;

AMINO ACID SEQUENCE; ANTIMICROBIAL ACTIVITY; ARTICLE; CHEMICAL STRUCTURE; DRUG POTENCY; GENE CLUSTER; GENE SEQUENCE; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; MARINE BACTERIUM; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; SEQUENCE HOMOLOGY; SERRATIA PLYMUTHICA;

AMINO ACID SEQUENCE; ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; CLONING, MOLECULAR; DNA TRANSPOSABLE ELEMENTS; FATTY ACID SYNTHETASE COMPLEX; GENE FUSION; GENE ORDER; MACROLIDES; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; MULTIGENE FAMILY; MUTAGENESIS, INSERTIONAL; PEPTIDE SYNTHASES; POLYAMINES; POLYKETIDE SYNTHASES; SEQUENCE ANALYSIS, DNA; SEQUENCE HOMOLOGY, AMINO ACID; SERRATIA; STAPHYLOCOCCUS AUREUS;

BACTERIA (MICROORGANISMS); NEGIBACTERIA; POSIBACTERIA; SERRATIA PLYMUTHICA;

EID: 84872506002     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0054143     Document Type: Article

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