Hydrogel containing silica shell cross-linked micelles for ocular drug delivery

Journal of Pharmaceutical Sciences

Volumn 102, Issue 2, 2013, Pages 627-637

  Lu, Changhai ^a   Yoganathan, Roshan B ^a   Kociolek, Michael ^a   Allen, Christine ^a  

^a UNIVERSITY OF TORONTO   (Canada)

Author keywords

Biomaterials; Block copolymer micelle; Controlled release; Dexamethasone; Hydrogels; Nanoparticles; Ophthalmic drug delivery; pHEMA; Shell cross linked; Silica

Indexed keywords

DEXAMETHASONE ACETATE; LYSOZYME; MACROGOL; METHOXY(POLYETHYLENE GLYCOL) BLOCK POLYCAPROLACTONE; POLY(2 HYDROXYETHYL METHACRYLATE METHACRYLIC ACID ETHYLENE GLYCOL DIMETHACRYLATE); SILICON DIOXIDE; UNCLASSIFIED DRUG;

ARTICLE; CROSS LINKING; DRUG DELIVERY SYSTEM; DRUG RELEASE; HYDROGEL; MICELLE; SCANNING ELECTRON MICROSCOPY;

EID: 84872499812     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.23390     Document Type: Article

References (68)

1. Kuno N, Fujii S. 2011. Recent advances in ocular drug delivery systems. Polymers 3(1):193-221.
2. Danion A, Arsenault I, Vermette P. 2007. Antibacterial activity of contact lenses bearing surface-immobilized layers of intact liposomes loaded with levofloxacin. J Pharm Sci 96(9):2350-2363.
3. Lavik E, Kuehn MH, Kwon YH. 2011. Novel drug delivery systems for glaucoma. Eye 25(5):578-586.
4. Short BG. 2008. Safety evaluation of ocular drug delivery formulations: Techniques and practical considerations. Toxicol Pathol 36(1):49-62.
5. Gulsen D, Chauhan A. 2004. Ophthalmic drug delivery through contact lenses. Invest Ophth Vis Sci 45(7):2342-2347.
6. Gulsen D, Chauhan A. 2005. Dispersion of microemulsion drops in HEMA hydrogel: A potential ophthalmic drug delivery vehicle. Int J Pharm 292(1-2):95-117.
7. Kapoor Y, Chauhan A. 2008. Ophthalmic delivery of cyclosporine A from Brij-97 microemulsion and surfactant-laden p-HEMA hydrogels. Int J Pharm 361(1-2):222-229.
8. Kim J, Chauhan A. 2008. Dexamethasone transport and ocular delivery from poly (hydroxyethyl methacrylate) gels. Int J Pharm 353(1-2):205-222.
9. Li CC, Chauhan A. 2006. Modeling ophthalmic drug delivery by soaked contact lenses. Ind Eng Chem Res 45(10):3718-3734.
10. del Amo EM, Urtti A. 2008. Current and future ophthalmic drug delivery systems. A shift to the posterior segment. Drug Discov Today 13(3-4):135-143.
11. Jain MR. 1988. Drug delivery through soft contact-lenses. Br J Ophthalmol 72(2):150-154.
12. Schultz C, Breaux J, Schentag J, Morck D. 2011. Drug delivery to the posterior segment of the eye through hydrogel contact lenses. Clin Exp Optom 94(2):212-218.
13. Hehl EM, Beck R, Luthard K, Guthoff R, Drewelow B. 1999. Improved penetration of aminoglycosides and fluoroquinolones into the aqueous humour of patients by means of Acuvue contact lenses. Eur J Clin Pharmacol 55(4):317-323.
14. Karlgard CCS, Wong NS, Jones LW, Moresoli C. 2003. In vitro uptake and release studies of ocular pharmaceutical agents by silicon-containing and p-HEMA hydrogel contact lens materials. Int J Pharm 257(1-2):141-151.
15. Boone A, Hui A, Jones L. 2009. Uptake and release of dexamethasone phosphate from silicone hydrogel and group I, II, and IV hydrogel contact lenses. Eye Contact Lens 35(5):260-267.
16. Chauhan A, Kim J, Conway A. 2008. Extended delivery of ophthalmic drugs by silicone hydrogel contact lenses. Biomaterials 29(14):2259-2269.
17. Kapoor Y, Chauhan A. 2008. Drug and surfactant transport in cyclosporine A and Brij 98 laden p-HEMA hydrogels. J Colloid Interface Sci 322(2):624-633.
18. Kapoor Y, Thomas JC, Tan G, John VT, Chauhan A. 2009. Surfactant-laden soft contact lenses for extended delivery of ophthalmic drugs. Biomaterials 30(5):867-878.
19. Venkatesh S, Sizemore SP, Byrne ME. 2007. Biomimetic hydrogels for enhanced loading and extended release of ocular therapeutics. Biomaterials 28(4):717-724.
20. Jung HJ, Chauhan A. 2012. Temperature sensitive contact lenses for triggered ophthalmic drug delivery. Biomaterials 33(7):2289-2300.
21. Alvarez-Lorenzo C, dos Santos JFR, Silva M, Balsa L, Couceiro J, Torres-Labandeira JJ, Concheiro A. 2009. Soft contact lenses functionalized with pendant cyclodextrins for controlled drug delivery. Biomaterials 30(7):1348-1355.
22. Peng CC, Kim J, Chauhan A. 2010. Extended delivery of hydrophilic drugs from silicone-hydrogel contact lenses containing vitamin E diffusion barriers. Biomaterials 31(14):4032-4047.
23. Peng CC, Burke MT, Chauhan A. 2012. Transport of topical anesthetics in vitamin E loaded silicone hydrogel contact lenses. Langmuir 28(2):1478-1487.
24. Peng CC, Chauhan A. 2011. Extended cyclosporine delivery by silicone-hydrogel contact lenses. J Control Release 154(3):267-274.
25. Ribeiro A, Veiga F, Santos D, Torres-Labandeira JJ, Concheiro A, Alvarez-Lorenzo C. 2012. Hydrophilic acrylic hydrogels with built-in or pendant cyclodextrins for delivery of anti-glaucoma drugs. Carbohydr Polym 88(3):977-985.
26. Wang CY, Javadi A, Ghaffari M, Gong SQ. 2010. A pH-sensitive molecularly imprinted nanospheres/hydrogel composite as a coating for implantable biosensors. Biomaterials 31(18):4944-4951.
27. Yanez F, Martikainen L, Braga MEM, Alvarez-Lorenzo C, Concheiro A, Duarte CMM, Gil MH, de Sousa HC. 2011. Supercritical fluid-assisted preparation of imprinted contact lenses for drug delivery. Acta Biomater 7(3):1019-1030.
28. Costa VP, Braga MEM, Guerra JP, Duarte ARC, Duarte CMM, Leite EOB, Gil MH, de Sousa HC. 2010. Development of therapeutic contact lenses using a supercritical solvent impregnation method. J Supercrit Fluid 52(3):306-316.
29. Malaekeh-Nikouei B, Ghaeni FA, Motamedshariaty VS, Mohajeri SA. 2012. Controlled release of prednisolone acetate from molecularly imprinted hydrogel contact lenses. J Appl Polym Sci 126(1):387-394.
30. Tieppo A, White CJ, Paine AC, Voyles ML, McBride MK, Byrne ME. 2012. Sustained in vivo release from imprinted therapeutic contact lenses. J Controlled Release 157(3):391-397.
31. Danion A, Brochu H, Martin Y, Vermette P. 2007. Fabrication and characterization of contact lenses bearing surface-immobilized layers of intact liposomes. J Biomed Mater Res A 82A(1):41-51.
32. Gulsen D, Chauhan A. 2006. Effect of water content on transparency, swelling, lidocaine diffusion in p-HEMA gels. J Membr Sci 269(1-2):35-48.
33. Gulsen D, Li CC, Chauhan A. 2005. Dispersion of DMPC liposomes in contact lenses for ophthalmic drug delivery. Curr Eye Res 30(12):1071-1080.
34. Li CC, Abrahamson M, Kapoor Y, Chauhan A. 2007. Timolol transport from microemulsions trapped in HEMA gels. J Colloid Interface Sci 315(1):297-306.
35. Fialho SL, Rego MB, Siqueira RC, Jorge R, Haddad A, Rodrigues AL, Maia A, Silva-Cunha A. 2006. Safety and pharmacokinetics of an intravitreal biodegradable implant of dexamethasone acetate in rabbit eyes. Curr Eye Res 31(6):525-534.
36. Allen C, Maysinger D, Eisenberg A. 1999. Nano-engineering block copolymer aggregates for drug delivery. Colloid Surf B 16(1-4):3-27.
37. Lu CH, Mikhail AS, Wang XY, Brook MA, Allen C. 2012. Hydrogels containing core cross-linked block co-polymer micelles. J Biomater Sci Polym Ed. 23:1069-1090.
38. Fairley N, Hoang B, Allen C. 2008. Morphological control of poly(ethylene glycol)-block-poly(epsilon-caprolactone) copolymer aggregates in aqueous solution. Biomacromolecules 9(9):2283-2291.
39. Liu J, Zeng F, Allen C. 2007. In vivo fate of unimers and micelles of a poly (ethylene glycol)-block-poly (caprolactone) copolymer in mice following intravenous administration. Eur J Pharm Biopharm 65(3):309-319.
40. Zhang Y, Jin T, Zhuo RX. 2005. Methotrexate-loaded biodegradable polymeric micelles: Preparation, physicochemical properties and in vitro drug release. Colloid Surf B 44(2-3):104-109.
41. Subbaraman LN, Jones L. 2010. Kinetics of lysozyme activity recovered from conventional and silicone hydrogel contact lens materials. J Biomater Sci Polym Ed. 21(3):343-358.
42. Kim J, Kim HS, Lee N, Kim T, Kim H, Yu T, Song IC, Moon WK, Hyeon T. 2008. Multifunctional uniform nanoparticles composed of a magnetite nanocrystal core and a mesoporous silica shell for magnetic resonance and fluorescence imaging and for drug delivery. Angew Chem Int Edit 47(44):8438-8441.
43. Zanarini S, Rampazzo E, Bonacchi S, Juris R, Marcaccio M, Montalti M, Paolucci F, Prodi L. 2009. Iridium doped silica-PEG nanoparticles: Enabling electrochemiluminescence of neutral complexes in aqueous media. J Am Chem Soc 131(40):14208-14209.
44. Chi FL, Guan BY, Yang B, Liu YL, Huo QS. 2010. Terminating effects of organosilane in the formation of silica cross-linked micellar-core shell nanoparticles. Langmuir 26(13):11421-11426.
45. Liu JB, Xiao YH, Allen C. 2004. Polymer-drug compatibility: A guide to the development of delivery systems for the anticancer agent, Ellipticine. J Pharm Sci 93(1):132-143.
46. Ward JH, Peppas NA. 2001. Preparation of controlled release systems by free-radical UV polymerizations in the presence of a drug. J Control Release 71(2):183-192.
47. Huo Q, Liu J, Wang LQ, Jiang Y, Lambert TN, Fang E. 2006. A new class of silica cross-linked micellar core-shell nanoparticles. J Am Chem Soc 128(19):6447-6453.
48. Korsmeyer RW, Gurny R, Doelker E. 1983. Mechanisms of solute release from porous hydrophilic polymers. IntJ Pharm 15(1):25-35.
49. Ende MTA, Peppas NA. 1997. Transport of ionizable drugs and proteins in crosslinked poly(acrylic acid) and poly(acrylic acid-co-2-hydroxyethyl methacrylate) hydrogels.2. Diffusion and release studies. J Control Release 48(1):47-56.
50. Ritger PL, Peppas NA. 1987. A simple equation for description of solute release I. Fickian and non-Fickian release from non-swellable devices in the form of slabs, spheres, cylinders or discs. J Control Release 5(1):23-36.
51. Arifin DY, Lee LY, Wang CH. 2006. Mathematical modeling and simulation of drug release from microspheres: Implications to drug delivery systems. Adv Drug Deliv Rev 58(12-13):1274-1325.
52. Peppas NA, Sahlin JJ. 1989. A simple equation for the description of solute release.3. Coupling of diffusion and relaxation. Int J Pharm 57(2):169-172.
53. Sonvico F, Oliveira PR, Bernardi LS, Strusi OL, Mercuri S, Silva MAS, Colombo P. 2011. Assembled modules technology for site-specific prolonged delivery of norfloxacin. Int J Pharm 405(1-2):90-96.
54. Georget DMR, Iravani S, Fitchett CS. 2011. Physical characterization of arabinoxylan powder and its hydrogel containing a methyl xanthine. Carbohydr Polym 85(1):201-207.
55. Goncalves-Araujo T, Rajabi-Siahboomi AR, Caraballo I. 2008. Application of percolation theory in the study of an extended release verapamil hydrochloride formulation. Int J Pharm 361(1-2):112-117.
56. Kim J, Conway A, Chauhan A. 2008. Extended delivery of ophthalmic drugs by silicone hydrogel contact lenses. Biomaterials 29(14):2259-2269.
57. Sack RA, Jones B, Antignani A, Libow R, Harvey H. 1987. Specificity and biological-activity of the protein deposited on the hydrogel surface-Relationship of polymer structure to biofilm formation. Invest Ophth Vis Sci 28(5):842-849.
58. Lord MS, Stenzel MH, Simmons A, Milthorpe BK. 2006. Lysozyme interaction with poly(HEMA)-based hydrogel. Biomaterials 27(8):1341-1345.
59. Bohnert JL, Horbett TA, Ratner BD, Royce FH. 1988. Adsorption of proteins from artificial tear solutions to contact-lens materials. Invest Ophth Vis Sci 29(3):362-373.
60. Baines MG, Cai F, Backman HA. 1990. Adsorption and removal of protein-bound to hydrogel contact-lenses. Optom Vis Sci 67(11):807-810.
61. Garrett Q, Garrett RW, Milthorpe BK. 1999. Lysozyme sorption in hydrogel contact lenses. Invest Ophth Vis Sci 40(5):897-903.
62. Subbaraman LN, Glasier MA, Senchyna M, Sheardown H, Jones L. 2006. Kinetics of in vitro lysozyme deposition on silicone hydrogel, PMMA, and FDA groups I, II, and IV contact lens materials. Curr Eye Res 31(10):787-796.
63. 2 thin-films. J Colloid Interface Sci 147(1):22-32.
64. Kopecek J. 2009. Hydrogels: From soft contact lenses and implants to self-assembled nanomaterials. J Polym Sci Polym Chem 47(22):5929-5946.
65. Ali M, Horikawa S, Venkatesh S, Saha J, Hong JW, Byrne ME. 2007. Zero-order therapeutic release from imprinted hydrogel contact lenses within in vitro physiological ocular tear flow. J Control Release 124(3):154-162.
66. Liu L, Sheardown H. 2005. Glucose permeable poly (dimethyl siloxane) poly (N-isopropyl acrylamide) interpenetrating networks as ophthalmic biomaterials. Biomaterials 26(3):233-244.
67. Tonge S, Jones L, Goodall S, Tighe B. 2001. The ex vivo wettability of soft contact lenses. Curr Eye Res 23(1):51-59.
68. Weeks A, Subbaraman LN, Jones L, Sheardown H. 2012. The competing effects of hyaluronic and methacrylic acid in model contact lenses. J Biomater Sci Polym Ed. 23:1021-1038.