Cloning, mapping and association studies of the ovine ABCG2 gene with facial eczema disease in sheep

Animal Genetics

Volumn 38, Issue 2, 2007, Pages 126-131

  Duncan, E J ^a   Dodds, K G ^b   Henry, H M ^a   Thompson, M P ^a   Phua, S H ^a  

^a UNIVERSITY OF OTAGO   (New Zealand)

^b INVERMAY AGRICULTURAL CENTRE   (New Zealand)

Author keywords

ABC transporter; Liver; Mycotoxin; Photosensitivity; Quantitative trait locus

Indexed keywords

ABC TRANSPORTER; PRIMER DNA;

ANIMAL; ANIMAL DISEASE; ARTICLE; COMPARATIVE STUDY; DNA SEQUENCE; ECZEMA; GENE FREQUENCY; GENETICS; IMMUNOLOGY; INNATE IMMUNITY; METABOLISM; MOLECULAR GENETICS; MYCOTOXICOSIS; NORTHERN BLOTTING; NUCLEOTIDE SEQUENCE; QUANTITATIVE TRAIT LOCUS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE HOMOLOGY; SHEEP; SHEEP DISEASE; SINGLE NUCLEOTIDE POLYMORPHISM;

ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; BASE SEQUENCE; BLOTTING, NORTHERN; DNA PRIMERS; ECZEMA; GENE FREQUENCY; IMMUNITY, NATURAL; MOLECULAR SEQUENCE DATA; MYCOTOXICOSIS; POLYMORPHISM, SINGLE NUCLEOTIDE; QUANTITATIVE TRAIT LOCI; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS, DNA; SEQUENCE HOMOLOGY; SHEEP; SHEEP DISEASES;

ANIMALIA; MAMMALIA; OVIS; OVIS ARIES;

EID: 34047142702     PISSN: 02689146     EISSN: 13652052     Source Type: Journal    
DOI: 10.1111/j.1365-2052.2006.01557.x     Document Type: Article

References (32)

1. Balzi E., Wang M., Leterme S., Van Dyck L. & Goffeau A. (1994) PDR5, a novel yeast multidrug resistance conferring transporter controlled by the transcription regulator PDR1. Journal of Biological Chemistry 269, 2206-14.
2. Bissinger P.H. & Kuchler K. (1994) Molecular cloning and expression of the Saccharomyces cerevisiae STS1 gene product. A yeast ABC transporter conferring mycotoxin resistance. Journal of Biological Chemistry 269, 4180-6.
3. Campbell A.G., Meyer H.H., Henderson H.V. & Wesselink C. (1981) Breeding for facial eczema resistance - a progress report. Proceedings of the New Zealand Society of Animal Production 41, 273-8.
4. Charlier C., Segers K., Karim L., Shay T., Gyapay G., Cockett N. & Georges M. (2001) The callipyge mutation enhances the expression of coregulated imprinted genes in cis without affecting their imprinting status. Nature Genetics 27, 367-9.
5. Churchill G.A. & Doerge R.W. (1994) Empirical threshold values for quantitative trait mapping. Genetics 138, 963-71.
6. Crawford A.M., Dodds K.G., Ede A.J. et al. (1995) An autosomal genetic linkage map of the sheep genome. Genetics 140, 703-24.
7. Dean M., Rzhetsky A. & Allikmets R. (2001) The Human ATP-binding cassette (ABC) transporter superfamily. Genome Research 11, 1156-66.
8. Dodds K.G. & McEwan J.C. (1997) Calculating exact probabilities of allele frequency differences in divergent selection lines. Proceedings of the Association for the Advancement of Animal Breeding and Genetics 12, 556-60.
9. Hohenboken W.D., Morris C.A., Munday R., De Nicolo G., Amyes N.C., Towers N.R. & Phua S.H. (2004) Antioxidants in blood from sheep lines divergently selected for facial eczema resistance. New Zealand Journal of Agricultural Research 47, 119-27.
10. Honjo Y., Hrycyna C.A., Yan Q.W., Medina-Perez W.Y., Robey R.W., de Laar A., Litman T., Dean M. & Bates S.E. (2001) Acquired mutations in the MXR/BCRP/ABCP gene alter substrate specificity in MXR/BCRP/ABCP- overexpressing cells. Cancer Research 61, 6635-9.
11. Honjo Y., Morisaki K., Huff L.M., Robey R.W., Hung J., Dean M. & Bates S.E. (2002) Single-nucleotide polymorphism (SNP) analysis in the ABC half-transporter ABCG2 (MXR/BCRP/ABCP1). Cancer Biology and Therapy 1, 696-702.
12. Jonker J.W., Buitelaar M., Wagenaar E. et al. (2002) The breast cancer resistance protein protects against a major chlorophyll-derived dietary phototoxin and protoporphyria. Proceedings of the National Academy of Sciences of the United States of America 99, 15649-54.
13. Jonker J.W., Merino G., Musters S., van Herwaarden A.E., Bolscher E., Wagenaar E., Mesman E., Dale T.C. & Schinkel A.H. (2005) The breast cancer resistance protein BCRP (ABCG2) concentrates drugs and carcinogenic xenotoxins into milk. Nature Medicine 11, 127-9.
14. Knott S.A., Elsen J.M. & Haley C.S. (1996) Methods for multiple-marker mapping of quantitative trait loci in half-sib populations. Theoretical and Applied Genetics 93, 71-80.
15. Krishnamurthy P. & Schuetz J.D. (2005) Role of ABCG2/BCRP in biology and medicine. Annual Review of Pharmacology and Toxicology 46, 381-410.
16. Krishnamurthy P., Ross D.D., Nakanishi T., Bailey-Dell K., Zhou S., Mercer K.E., Sarkadi B., Sorrentino B.P. & Schuetz J.D. (2004) The stem cell marker Bcrp/ABCG2 enhances hypoxic cell survival through interactions with heme. Journal of Biological Chemistry 279, 24218-25.
17. Lander E. & Kruglyak L. (1995) Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results. Nature Genetics 11, 241-7.
18. Longley M., Phua S.H., van Stijn T.C. & Crawford A.M. (1999) Isolation and mapping of the first ruminant multidrug resistance genes. Animal Genetics 30, 207-10.
19. Maddox J.F., Davies K.P., Crawford A.M. et al. (2001) An enhanced linkage map of the sheep genome comprising more than 1000 loci. Genome Research 11, 1275-89.
20. Mickley L., Jain P., Miyake K., Schriml L.M., Rao K., Fojo T., Bates S. & Dean M. (2001) An ATP-binding cassette gene (ABCG3) closely related to the multidrug transporter ABCG2 (MXR/ABCP) has an unusual ATP-binding domain. Mammalian Genome 12, 86-8.
21. Mizuarai S., Aozasa N. & Kotani H. (2004) Single nucleotide polymorphisms result in impaired membrane localization and reduced ATPase activity in multidrug transporter ABCG2. International Journal of Cancer 109, 238-46.
22. Morris C.A., Towers N.R., Campbell A.G., Meyer H.H., Wesselink C. & Wheeler M. (1989) Responses achieved in Romney flocks selected for or against susceptibility to facial eczema, 1975-87. New Zealand Journal of Agricultural Research 32, 379-88.
23. Morris C.A., Towers N.R., Hohenboken W.D., Maqbool N., Smith B.L. & Phua S.H. (2004) Inheritance of resistance to facial eczema: a review of research findings from sheep and cattle in New Zealand. New Zealand Veterinary Journal 52, 205-15.
24. Mortimer P.H. & Ronaldson J.W. (1983) Fungal toxin induced photosensitisation. In: Handbook of Natural Toxins, vol. 1 (Ed. by R.F. Keeler & A.T. Tu ), pp. 361-419. Plant and Fungal Toxins, Dekker, New York.
25. Phua S.H., Dodds K.G., Morris C.A., Paterson K.A., McEwan J.C., Garmonsway H.G., Towers N.R. & Crawford A.M. (1999) Catalase gene is associated with facial eczema disease resistance in sheep. Animal Genetics 30, 286-95.
26. Ponting C.P. (2001) Issues in predicting protein function from sequence. Briefings in Bioinformatics 2, 19-29.
27. Schmitz G., Langmann T. & Heimerl S. (2001) Role of ABCG1 and other ABCG family members in lipid metabolism. Journal of Lipid Research 42, 1513-20.
28. Sheps J.A., Ralph S., Zhao Z., Baillie D.L. & Ling V. (2004) The ABC transporter gene family of Caenorhabditis elegans has implications for the evolutionary dynamics of multidrug resistance in eukaryotes. Genome Biology 5, R15.
29. Staud F. & Pavek P. (2005) Breast cancer resistance protein (BCRP/ABCG2). The International Journal of Biochemistry and Cell Biology 37, 720-5.
30. Tang K., Fu D.J., Julien D., Braun A., Cantor C.R. & Koster H. (1999) Chip-based genotyping by mass spectrometry. Proceedings of the National Academy of Sciences of the United States of America 96, 10016-20.
31. Wheelan S.J., Church D.M. & Ostell J.M. (2001) Spidey: a tool for mRNA-to-genomic alignments. Genome Research 11, 1952-7.
32. Zhang Z., Schwartz S., Wagner L. & Miller W. (2000) A greedy algorithm for aligning DNA sequences. Journal of Computational Biology 7, 203-14.