Phospholipid signaling in apoptosis: peroxidation and externalization of phosphatidylserine

Toxicology

Volumn 148, Issue 2-3, 2000, Pages 93-101

  Tyurina, Y Y ^a   Shvedova, A A ^b   Kawai, K ^a   Tyurin, V A ^a,c   Kommineni, C ^b   Quinn, P J ^d   Schor, N F ^c   Fabisiak, J P ^a   Kagan, V E ^a,c,d  

^a UNIVERSITY OF PITTSBURGH   (United States)

^b NATIONAL INSTITUTE FOR OCCUPATIONAL SAFETY AND HEALTH   (United States)

^c UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^d KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Antioxidants; Apoptosis; Oxidative stress; Phosphatidylserine

Indexed keywords

ANTIOXIDANT; CARRIER PROTEIN; CYTOCHROME C; PHOSPHATIDYLSERINE; PHOSPHOLIPID;

APOPTOSIS; CELL STRAIN HL 60; CONFERENCE PAPER; GENE EXPRESSION; HUMAN; MITOCHONDRION; OXIDATIVE STRESS; PEROXIDATION; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ANIMALS; APOPTOSIS; AZO COMPOUNDS; BIOLOGICAL TRANSPORT; GENE EXPRESSION REGULATION; HL-60 CELLS; HUMANS; KERATINOCYTES; LIPID PEROXIDATION; NITRILES; PC12 CELLS; PHENOL; PHOSPHATIDYLSERINES; PHOSPHOLIPIDS; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; SIGNAL TRANSDUCTION;

EID: 0034618030     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0300-483X(00)00199-2     Document Type: Conference Paper

References (47)

1. Burton G.W., Ingold K.U. Vitamin E as in vitro and in vivo antioxidant. Ann. NY Acad. Sci. 570:1989;7-22.
2. Bratton D.L., Fadok V.A., Richter D.A., Kailey J.M., Guthrie L.A., Henson P.M. Appearance of phosphatidylserine on apoptotic cells requires calcium-mediated nonspecific flip-flop and is enhanced by loss of the aminophospholipid translocase. J. Biol. Chem. 272:1997;26159-26165.
3. Bruckheimer E.M., Schroit A.J. Mechanisms of phosphatidylserine exposure, a phagocyte recognition signal, on apoptotic T lymphocytes. J. Leukocyte Biol. 59:1996;784-788.
4. Cortazzo M., Schor N.F. Potentiation of enediyene-induced apoptosis and differentiation by Bcl-2. Cancer Res. 56:1996;1199-1203.
5. 2 in myocardium. Mol. Cell Biochem. 157:1996;199-210.
6. Fabisiak J.P., Kagan V.E., Ritov V.B., Jonhson D.E., Lazo J.S. Bcl-2 inhibits selective oxidation and externalization of phosphatidylserine during paraquat-induced apoptosis. Am. J. Physiol. (Cell Physiol.). 272:1997;C675-C684.
7. Fabisiak J.P., Tyurina Y.Y., Tyurin V.A., Lazo J.S., Kagan V.E. Random versus selective membrane phospholipid oxidation in apoptosis: role of phosphatidylserine. Biochemistry. 37:1998;13781-13790.
8. Fabisiak J.P., Kagan V.E., Tyurina Y.Y., Tyurin V.A., Lazo J.S. Paraquat-induced phosphatidylserine oxidation and apoptosis are independent of activation of PLA2. Am. J. Physiol. (Lung Cell. Mol. Physiol.). 274:1998;L793-L802.
9. Fabisiak, J.P., Tyurin, V.A., Tyurina, Y.Y., Sedlov, A., Lazo, J.S., Kagan, V.E., 1999. Nitric oxide dissociates lipid peroxidation from apoptosis and phosphatidylserine externalization during oxidative stress. Biochemistry 39, 127-138.
10. Fadok V.A., Voelker D.R., Campbell P.A., Cohen J.J., Bratton D.L., Henson P.M. Exposure of phosphatidylserine on the surface of apoptotic lymphocytes triggers specific recognition and removal by macrophages. J. Immunol. 148:1992;2201-2216.
11. Fadok V.A., Bratton D.L., Frasch S.C., Warner M.L., Henson P.M. The role of phosphatidylserine in recognition of apoptotic cell by phagocytes. Cell Death Differ. 5:1998;551-562.
12. Glaesser D., Fass U., Gruner M., Thust O., Iwig M., Spindler M. Low concentration of cis-linoleic acid induce cell damage in epithelial cells from bovine lenses. Eur. J. Cell Biol. 7:1996;286-292.
13. Gorbunov N.V., Tyurina Y.Y., Salama G. et al. Nitric oxide protects cardiomyocytes against tert-BuOOH hydroperoxide-induced formation of alkoxyl and peroxyl radicals and peroxidation of phosphatidylserine. Biochem. Biophys. Res. Commun. 244:1998;647-651.
14. Green D.R., Reed J.C. Mitochondria and apoptosis. Science. 281:1998;1309-1312.
15. Hampton M.B., Vanags D.M., Porn-Ares I., Orrenius S. Involvement of extracellular calcium in phosphatidylserine exposure during apoptosis. FEBS Lett. 399:1996;277-282.
16. Hockenbery D.M., Oltavi Z.N., Yin X.-M., Millan C.L., Korsmeyer S.J. Bcl-2 functions in an antioxidant pathway to prevent apoptosis. Cell. 75:1993;241-251.
17. Kagan V.E. Lipid Peroxidation in Biomembranes. 1988;1-11 CRC Press, Boca Raton, FL.
18. Kagan V.E., Serbinova E.A., Bakalova R.A. et al. Mechanism of stabilization of biomembranes by alpha-tocopherol. The role of the hydrocarbon chain in the inhibition of lipid peroxidation. Biochem. Pharmacol. 40:1990;2403-2413.
19. Kagan V.E., Ritov V.B., Tyurina Y.Y., Tyurin V.A. Sensitive and specific fluorescent probing of oxidative stress in different classes of membrane phospholipids in live cells using metabolically integrated cis-parinaric acid. Methods Mol. Biol. 108:1998;71-87.
20. Kane D.J., Sarafian T., Anton R. et al. Bcl-2 inhibition of neural death: decreased generation of reactive oxygen species. Science. 262:1993;1274-1277.
21. Kaneko T., Baba N. Protective effect of flavonoids on endothelial cells against linoleic acid hydroperoxide-induced toxicity. Biosci. Biotechnol. Biochem. 63:1999;323-328.
22. Krainev A.G., Bigelow D.J. Comparison of 2,2′azobis(2-aminopropane) hydrochloride (AAPH) and 2,2′azobis(2,3-dimethylvaleronitrile) (AMVN) as free radical initiators: a spin-trapping study. J. Chem. Soc. Perkin Trans. 2:1996;747-754.
23. Kuypers F.A., Van den Berg J.J.M., Schalkwijk C., Roelofsen B., Op den Kamp J.A.F. Parinaric acid as a sensitive fluorescent probe for the determination of lipid peroxidation. Biochim. Biophys. Acta. 921:1987;266-274.
24. Malisan F., Rippo M.R., De Maria R., Tesi R. Lipid and glycolipid mediators in CD95-induced apoptotic signaling. Results Probl. Cell Differ. 23:1999;65-76.
25. Martin T.F. Phosphoinositide lipids as signaling molecules: common themes for signal transduction, cytoskeletal regulation, and membrane trafficking. Annu. Rev. Cell Dev. Biol. 14:1998;231-264.
26. Martin O.C., Pagano R.E. Transbilayer movement of fluorescent analogs of phosphatidylserine and phosphatidylethanolamine at plasma membrane of cultured cells. Evidence for a protein-mediated and ATP-dependent process(es). J. Biol. Chem. 262:1987;5890-5898.
27. Mathias S., Pena L.A., Kolesnick R.N. Signal transduction of stress via ceramide. Biochem. J. 335:1998;465-480.
28. Maulik N., Kagan V.E., Tyurin V.A., Das D.K. Redistribution of phosphatidylethanolamine and phosphatidylserine precedes reperfusion-induced apoptosis. Am. J. Physiol. 274:1998;H242-H248.
29. Mignotte B., Vayssiere J.L. Mitochondria and apoptosis. Eur. J. Biochem. 252:1998;1-15.
30. Niki E. Free radical initiators as source of water- or lipid-soluble peroxyl radicals. Methods Enzymol. 186:1990;100-108.
31. Ohanian J., Liu G., Ohanian V., Heagerty A.M. Lipid second messengers derived from glycerolipids and sphingolipids, and their role in smooth muscle function. Acta Physiol. Scand. 164:1998;533-548.
32. Pacifici E.H., McLeod L.L., Peterson H., Sevanian A. Linoleic acid hydroperoxide-induced peroxidation of endothelial cells phospholipid and cytotoxicity. Free Radic. Biol. Med. 17:1994;285-295.
33. Pacifici E.H., McLeod L.L., Sevanian A. Lipid hydroperoxide-induced peroxidation and turnover of endothelial cell phospholipids. Free Radic. Biol. Med. 17:1994;297-309.
34. Perry D.K., Hannun Y.A. The role of ceramide in cell signaling. Biochim. Biophys. Acta. 1436:1998;233-243.
35. Reno F., Burattini S., Rossi S. et al. Phospholipid rearrangement of apoptotic membrane does not depend on nuclear activity. Histochem. Cell Biol. 110:1998;467-476.
36. Rintoul D.A., Simoni R.D. Incorporation of a naturally occurring fluorescent fatty acid into phospholipids of cultured mammalian cells. J. Biol. Chem. 252:1977;7916-7918.
37. Ritov V.B., Banni S., Yalowich J.C. et al. Non-random peroxidation of different classes of membrane phospholipids in live cells detected by metabolically integrated cis-parinaric acid. Biochim. Biophys. Acta. 1283:1996;127-140.
38. 2 hydrolytic susceptibility of liposomes consisting of mixed species of phosphatidylcholine and phosphatidylethanolamine. Biochim. Biophys. Acta. 1127:1992;131-140.
39. Schor N.F., Tyurina Y.Y., Fabisiak J.P., Tyurin V.A., Lazo J.S., Kagan V.E. Bcl-2-induced potentiation of apoptosis: enhancement of reducing potential and externalization of membrane phosphatidylserine. Mol. Brain Res. 831:1999;125-130.
40. Shvedova, A.A., Kommineni, C., Jeffreis, B.A. et al., 2000. Redox-cycling of phenol induced oxidative stress in human epidermal keratinocytes. J. Invest. Dermatol. 114, 354-364.
41. Smith C.V. Evidence for participation of lipid peroxidation and iron in diquat-induced hepatic necrosis in vitro. Mol. Pharmacol. 32:1987;417-422.
42. Tyurina Y.Y., Tyurin V.A., Carta C., Quinn P.J., Schor N.F., Kagan V.E. Direct evidence for antioxidant effect of Bcl-2 in PC12 rat pheochromocytoma cells. Arch. Biochem. Biophys. 344:1997;413-432.
43. Tyurin V.A., Tyurina Y.Y., Quinn P.J. et al. Glutamate-induced cytotoxicity in PC12 pheochromocytoma cells: role of oxidation of phospholipids, glutathione and protein sulfhydryls revealed by bcl-2 transfection. Mol. Brain Res. 60:1998;270-281.
44. Verhoven B., Schleger R.A., Williamson P. Membrane phospholipid asymmetry: host response to the externalization of phosphatidylserine. J. Exp. Med. 182:1995;1597-1601.
45. Versteeg H.H., van Bergen en Henegouwen P.M., van Deventer S.J., Peppelenbosch M.P. Cyclooxygenase-dependent signaling: molecular events and consequences. FEBS Lett. 445:1999;1-5.
46. Welti R. Partition of parinaroyl phospholipids in mixed head group system. Biochemistry. 21:1982;5690-5693.
47. Wilton D.C. Anionic phospholipids and the regulation of cell functions. Biochem. Soc. Trans. 26:1998;378-383.