메뉴 건너뛰기




Volumn 6, Issue , 2008, Pages

Modelling neurofibromatosis type 1 tibial dysplasia and its treatment with lovastatin

Author keywords

[No Author keywords available]

Indexed keywords

METHACRYLIC ACID; MEVINOLIN; MITOGEN ACTIVATED PROTEIN KINASE; PARAFFIN; TRANSCRIPTION FACTOR RUNX2; PRIMER DNA;

EID: 49949110162     PISSN: None     EISSN: 17417015     Source Type: Journal    
DOI: 10.1186/1741-7015-6-21     Document Type: Article
Times cited : (45)

References (33)
  • 5
    • 0042889307 scopus 로고    scopus 로고
    • Establishment of a model of cortical bone repair in mice
    • 10.1007/s00223-002-2120-4 14506954
    • Campbell TM Wong WT Mackie EJ Establishment of a model of cortical bone repair in mice Calcif Tissue Int 2003, 73(1):49-55. 10.1007/ s00223-002-2120-4 14506954
    • (2003) Calcif Tissue Int , vol.73 , Issue.1 , pp. 49-55
    • Campbell, T.M.1    Wong, W.T.2    Mackie, E.J.3
  • 6
    • 14644394972 scopus 로고    scopus 로고
    • The role of protease-activated receptor-1 in bone healing
    • 1602347 15743797
    • Song SJ Pagel CN Campbell TM Pike RN Mackie EJ The role of protease-activated receptor-1 in bone healing Am J Pathol 2005, 166(3):857-868. 1602347 15743797
    • (2005) Am J Pathol , vol.166 , pp. 857-868
    • Song, S.J.1    Pagel, C.N.2    Campbell, T.M.3    Pike, R.N.4    Mackie, E.J.5
  • 7
    • 34547479240 scopus 로고    scopus 로고
    • Congenital pseudarthrosis of the tibia: Analysis of the histology and the NF1 gene
    • 10.1007/s00776-007-1142-1 17657556
    • Sakamoto A Yoshida T Yamamoto H Oda Y Tsuneyoshi M Iwamoto Y Congenital pseudarthrosis of the tibia: Analysis of the histology and the NF1 gene J Orthop Sci 2007, 12:4 361-365. 10.1007/s00776-007-1142-1 17657556
    • (2007) J Orthop Sci , vol.12 , pp. 361-365
    • Sakamoto, A.1    Yoshida, T.2    Yamamoto, H.3    Oda, Y.4    Tsuneyoshi, M.5    Iwamoto, Y.6
  • 9
    • 32544451475 scopus 로고    scopus 로고
    • Potent inhibition of small-cell lung cancer cell growth by simvastatin reveals selective functions of Ras isoforms in growth factor signalling
    • 10.1038/sj.onc.1209117 16170339
    • Khanzada UK Pardo OE Meier C Downward J Seckl MJ Arcaro A Potent inhibition of small-cell lung cancer cell growth by simvastatin reveals selective functions of Ras isoforms in growth factor signalling Oncogene 2006, 25(6):877-887. 10.1038/sj.onc.1209117 16170339
    • (2006) Oncogene , vol.25 , Issue.6 , pp. 877-887
    • Khanzada, U.K.1    Pardo, O.E.2    Meier, C.3    Downward, J.4    Seckl, M.J.5    Arcaro, A.6
  • 10
    • 27244450832 scopus 로고    scopus 로고
    • Combining prenylation inhibitors causes synergistic cytotoxicity, apoptosis and disruption of RAS-to-MAP kinase signalling in multiple myeloma cells
    • 10.1111/j.1365-2141.2005.05696.x 16156861
    • Morgan MA Sebil T Aydilek E Peest D Ganser A Reuter CW Combining prenylation inhibitors causes synergistic cytotoxicity, apoptosis and disruption of RAS-to-MAP kinase signalling in multiple myeloma cells Br J Haematol 2005, 130(6):912-925. 10.1111/j.1365-2141.2005.05696.x 16156861
    • (2005) Br J Haematol , vol.130 , Issue.6 , pp. 912-925
    • Morgan, M.A.1    Sebil, T.2    Aydilek, E.3    Peest, D.4    Ganser, A.5    Reuter, C.W.6
  • 12
    • 34948814564 scopus 로고    scopus 로고
    • Locally delivered lovastatin nanoparticles enhance fracture healing in rats
    • 10.1002/jor.20391 17506505
    • Garrett IR Gutierrez GE Rossini G Nyman J McCluskey B Flores A Mundy GR Locally delivered lovastatin nanoparticles enhance fracture healing in rats J Orthop Res 2007, 25(10):1351-1357. 10.1002/jor.20391 17506505
    • (2007) J Orthop Res , vol.25 , Issue.10 , pp. 1351-1357
    • Garrett, I.R.1    Gutierrez, G.E.2    Rossini, G.3    Nyman, J.4    McCluskey, B.5    Flores, A.6    Mundy, G.R.7
  • 13
    • 38349065432 scopus 로고    scopus 로고
    • Locally applied Simvastatin improves fracture healing in mice
    • 2200653 17897477 10.1186/1471-2474-8-98
    • Skoglund B Aspenberg P Locally applied Simvastatin improves fracture healing in mice BMC Musculoskelet Disord 2007, 8:98. 2200653 17897477 10.1186/1471-2474-8-98
    • (2007) BMC Musculoskelet Disord , vol.8 , pp. 98
    • Skoglund, B.1    Aspenberg, P.2
  • 14
    • 0036828513 scopus 로고    scopus 로고
    • Simvastatin improves fracture healing in mice
    • 10.1359/jbmr.2002.17.11.2004 12412808
    • Skoglund B Forslund C Aspenberg P Simvastatin improves fracture healing in mice J Bone Miner Res 2002, 17(11):2004-2008. 10.1359/ jbmr.2002.17.11.2004 12412808
    • (2002) J Bone Miner Res , vol.17 , Issue.11 , pp. 2004-2008
    • Skoglund, B.1    Forslund, C.2    Aspenberg, P.3
  • 15
    • 0035929257 scopus 로고    scopus 로고
    • Pitavastatin enhanced BMP-2 and osteocalcin expression by inhibition of Rho-associated kinase in human osteoblasts
    • 10.1006/bbrc.2001.5597 11554731
    • Ohnaka K Shimoda S Nawata H Shimokawa H Kaibuchi K Iwamoto Y Takayanagi R Pitavastatin enhanced BMP-2 and osteocalcin expression by inhibition of Rho-associated kinase in human osteoblasts Biochem Biophys Res Commun 2001, 287(2):337-342. 10.1006/bbrc.2001.5597 11554731
    • (2001) Biochem Biophys Res Commun , vol.287 , Issue.2 , pp. 337-342
    • Ohnaka, K.1    Shimoda, S.2    Nawata, H.3    Shimokawa, H.4    Kaibuchi, K.5    Iwamoto, Y.6    Takayanagi, R.7
  • 16
    • 13044283050 scopus 로고    scopus 로고
    • Alendronate mechanism of action: Geranylgeraniol, an intermediate in the mevalonate pathway, prevents inhibition of osteoclast formation, bone resorption, and kinase activation in vitro
    • 15105 9874784 10.1073/pnas.96.1.133
    • Fisher JE Rogers MJ Halasy JM Luckman SP Hughes DE Masarachia PJ Wesolowski G Russell RG Rodan GA Reszka AA Alendronate mechanism of action: Geranylgeraniol, an intermediate in the mevalonate pathway, prevents inhibition of osteoclast formation, bone resorption, and kinase activation in vitro Proc Natl Acad Sci USA 1999, 96(1):133-138. 15105 9874784 10.1073/pnas.96.1.133
    • (1999) Proc Natl Acad Sci USA , vol.96 , Issue.1 , pp. 133-138
    • Fisher, J.E.1    Rogers, M.J.2    Halasy, J.M.3    Luckman, S.P.4    Hughes, D.E.5    Masarachia, P.J.6    Wesolowski, G.7    Russell, R.G.8    Rodan, G.A.9    Reszka, A.A.10
  • 17
    • 29944441329 scopus 로고    scopus 로고
    • Statins and osteoporosis: New role for old drugs
    • 10.1211/jpp.58.1.0002 16393459
    • Jadhav SB Jain GK Statins and osteoporosis: New role for old drugs J Pharm Pharmacol 2006, 58(1):3-18. 10.1211/jpp.58.1.0002 16393459
    • (2006) J Pharm Pharmacol , vol.58 , Issue.1 , pp. 3-18
    • Jadhav, S.B.1    Jain, G.K.2
  • 18
    • 27644517404 scopus 로고    scopus 로고
    • The HMG-CoA reductase inhibitor lovastatin reverses the learning and attention deficits in a mouse model of neurofibromatosis type 1
    • 10.1016/j.cub.2005.09.043 16271875
    • Li W Cui Y Kushner SA Brown RA Jentsch JD Frankland PW Cannon TD Silva AJ The HMG-CoA reductase inhibitor lovastatin reverses the learning and attention deficits in a mouse model of neurofibromatosis type 1 Curr Biol 2005, 15(21):1961-1967. 10.1016/j.cub.2005.09.043 16271875
    • (2005) Curr Biol , vol.15 , Issue.21 , pp. 1961-1967
    • Li, W.1    Cui, Y.2    Kushner, S.A.3    Brown, R.A.4    Jentsch, J.D.5    Frankland, P.W.6    Cannon, T.D.7    Silva, A.J.8
  • 19
    • 0035312367 scopus 로고    scopus 로고
    • Ablation of NF1 function in neurons induces abnormal development of cerebral cortex and reactive gliosis in the brain
    • 312666 11297510 10.1101/gad.862101
    • Zhu Y Romero MI Ghosh P Ye Z Charnay P Rushing EJ Marth JD Parada LF Ablation of NF1 function in neurons induces abnormal development of cerebral cortex and reactive gliosis in the brain Genes Dev 2001, 15(7):859-876. 312666 11297510 10.1101/gad.862101
    • (2001) Genes Dev , vol.15 , Issue.7 , pp. 859-876
    • Zhu, Y.1    Romero, M.I.2    Ghosh, P.3    Ye, Z.4    Charnay, P.5    Rushing, E.J.6    Marth, J.D.7    Parada, L.F.8
  • 20
    • 0019140920 scopus 로고
    • Feedback regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase in livers of mice treated with mevinolin, a competitive inhibitor of the reductase
    • 371547 6903572 10.1172/JCI109938
    • Kita T Brown MS Goldstein JL Feedback regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase in livers of mice treated with mevinolin, a competitive inhibitor of the reductase J Clin Invest 1980, 66(5):1094-1100. 371547 6903572 10.1172/JCI109938
    • (1980) J Clin Invest , vol.66 , Issue.5 , pp. 1094-1100
    • Kita, T.1    Brown, M.S.2    Goldstein, J.L.3
  • 21
    • 39749201086 scopus 로고    scopus 로고
    • Redundant function of the heparan sulfate 6-O-endosulfatases Sulf1 and Sulf2 during skeletal development
    • 10.1002/dvdy.21423 18213582
    • Ratzka A Kalus I Moser M Dierks T Mundlos S Vortkamp A Redundant function of the heparan sulfate 6-O-endosulfatases Sulf1 and Sulf2 during skeletal development Dev Dyn 2008, 237(2):339-353. 10.1002/ dvdy.21423 18213582
    • (2008) Dev Dyn , vol.237 , Issue.2 , pp. 339-353
    • Ratzka, A.1    Kalus, I.2    Moser, M.3    Dierks, T.4    Mundlos, S.5    Vortkamp, A.6
  • 22
    • 0029750190 scopus 로고    scopus 로고
    • Regulation of rate of cartilage differentiation by Indian hedgehog and PTH-related protein
    • 10.1126/science.273.5275.613 8662546
    • Vortkamp A Lee K Lanske B Segre GV Kronenberg HM Tabin CJ Regulation of rate of cartilage differentiation by Indian hedgehog and PTH-related protein Science 1996, 273(5275):613-622. 10.1126/science.273.5275.613 8662546
    • (1996) Science , vol.273 , Issue.5275 , pp. 613-622
    • Vortkamp, A.1    Lee, K.2    Lanske, B.3    Segre, G.V.4    Kronenberg, H.M.5    Tabin, C.J.6
  • 23
    • 0033529194 scopus 로고    scopus 로고
    • Osteopontin-deficient mice are resistant to ovariectomy-induced bone resorption
    • 22204 10393964 10.1073/pnas.96.14.8156
    • Yoshitake H Rittling SR Denhardt DT Noda M Osteopontin-deficient mice are resistant to ovariectomy-induced bone resorption Proc Natl Acad Sci USA 1999, 96(14):8156-8160. 22204 10393964 10.1073/pnas.96.14.8156
    • (1999) Proc Natl Acad Sci USA , vol.96 , Issue.14 , pp. 8156-8160
    • Yoshitake, H.1    Rittling, S.R.2    Denhardt, D.T.3    Noda, M.4
  • 24
    • 0035094338 scopus 로고    scopus 로고
    • Osteopontin facilitates angiogenesis, accumulation of osteoclasts, and resorption in ectopic bone
    • 10.1210/en.142.3.1325 11181551
    • Asou Y Rittling SR Yoshitake H Tsuji K Shinomiya K Nifuji A Denhardt DT Noda M Osteopontin facilitates angiogenesis, accumulation of osteoclasts, and resorption in ectopic bone Endocrinology 2001, 142(3):1325-1332. 10.1210/en.142.3.1325 11181551
    • (2001) Endocrinology , vol.142 , Issue.3 , pp. 1325-1332
    • Asou, Y.1    Rittling, S.R.2    Yoshitake, H.3    Tsuji, K.4    Shinomiya, K.5    Nifuji, A.6    Denhardt, D.T.7    Noda, M.8
  • 26
    • 0025891066 scopus 로고
    • Hypophosphatemic osteomalacia in von Recklinghausen neurofibromatosis
    • 10.1097/00000441-199105000-00006 1902351
    • Konishi K Nakamura M Yamakawa H Suzuki H Saruta T Hanaoka H Davatchi F Hypophosphatemic osteomalacia in von Recklinghausen neurofibromatosis Am J Med Sci 1991, 301(5):322-328. 10.1097/00000441-199105000-00006 1902351
    • (1991) Am J Med Sci , vol.301 , Issue.5 , pp. 322-328
    • Konishi, K.1    Nakamura, M.2    Yamakawa, H.3    Suzuki, H.4    Saruta, T.5    Hanaoka, H.6    Davatchi, F.7
  • 27
    • 0025289542 scopus 로고
    • Hypercalcemic hyperparathyroidism and hypophosphatemic osteomalacia complicating neurofibromatosis
    • 10.1007/BF02554965 2114209
    • Weinstein RS Harris RL Hypercalcemic hyperparathyroidism and hypophosphatemic osteomalacia complicating neurofibromatosis Calcif Tissue Int 1990, 46(6):361-366. 10.1007/BF02554965 2114209
    • (1990) Calcif Tissue Int , vol.46 , Issue.6 , pp. 361-366
    • Weinstein, R.S.1    Harris, R.L.2
  • 28
    • 23744514711 scopus 로고    scopus 로고
    • Decreased bone mineral density and content in neurofibromatosis type 1: Lowest local values are located in the load-carrying parts of the body
    • 10.1007/s00198-004-1801-4 15551055
    • Kuorilehto T Poyhonen M Bloigu R Heikkinen J Vaananen K Peltonen J Decreased bone mineral density and content in neurofibromatosis type 1: lowest local values are located in the load-carrying parts of the body Osteoporos Int 2005, 16(8):928-936. 10.1007/s00198-004-1801-4 15551055
    • (2005) Osteoporos Int , vol.16 , Issue.8 , pp. 928-936
    • Kuorilehto, T.1    Poyhonen, M.2    Bloigu, R.3    Heikkinen, J.4    Vaananen, K.5    Peltonen, J.6
  • 29
    • 0028204188 scopus 로고
    • Oncogenic osteomalacia induced by schwannoma in a patient with neurofibromatosis
    • 8131871
    • Ben-Baruch D Ziv Y Sandbank J Wolloch Y Oncogenic osteomalacia induced by schwannoma in a patient with neurofibromatosis Eur J Surg Oncol 1994, 20(1):57-61. 8131871
    • (1994) Eur J Surg Oncol , vol.20 , Issue.1 , pp. 57-61
    • Ben-Baruch, D.1    Ziv, Y.2    Sandbank, J.3    Wolloch, Y.4
  • 30
    • 0036183646 scopus 로고    scopus 로고
    • Directions of drug discovery in osteoporosis
    • 10.1146/annurev.med.53.082901.104047 11818478
    • Mundy GR Directions of drug discovery in osteoporosis Annu Rev Med 2002, 53:337-354. 10.1146/annurev.med.53.082901.104047 11818478
    • (2002) Annu Rev Med , vol.53 , pp. 337-354
    • Mundy, G.R.1
  • 31
    • 0026895892 scopus 로고
    • Protein prenylation: Key to ras function and cancer intervention?
    • 1419908
    • Khosravi-Far R Cox AD Kato K Der CJ Protein prenylation: Key to ras function and cancer intervention? Cell Growth Differ 1992, 3(7):461-469. 1419908
    • (1992) Cell Growth Differ , vol.3 , Issue.7 , pp. 461-469
    • Khosravi-Far, R.1    Cox, A.D.2    Kato, K.3    Der, C.J.4
  • 32
    • 33751412300 scopus 로고    scopus 로고
    • ATF4 mediation of NF1 functions in osteoblast reveals a nutritional basis for congenital skeletal dysplasiae
    • 10.1016/j.cmet.2006.10.010 17141628
    • Elefteriou F Benson MD Sowa H Starbuck M Liu X Ron D Parada LF Karsenty G ATF4 mediation of NF1 functions in osteoblast reveals a nutritional basis for congenital skeletal dysplasiae Cell Metab 2006, 4(6):441-451. 10.1016/j.cmet.2006.10.010 17141628
    • (2006) Cell Metab , vol.4 , Issue.6 , pp. 441-451
    • Elefteriou, F.1    Benson, M.D.2    Sowa, H.3    Starbuck, M.4    Liu, X.5    Ron, D.6    Parada, L.F.7    Karsenty, G.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.