Effects of short-term exposure to environmentally relevant concentrations of different pharmaceutical mixtures on the immune response of the pond snail Lymnaea stagnalis

Science of the Total Environment

Volumn 445-446, Issue , 2013, Pages 210-218

  Gust, M ^a,b   Fortier, M ^c   Garric, J ^a   Fournier, M ^c   Gagne F ^b,c  

^a CEMAGREF   (France)

^b ENVIRONMENT CANADA   (Canada)

^c INRS INSTITUT ARMAND FRAPPIER   (Canada)

Author keywords

Effluent; Gastropods; Gene expression; Immunocompetence; Pharmaceuticals

Indexed keywords

AQUATIC ENVIRONMENTS; ATENOLOL; ATORVASTATIN; CARBAMAZEPINE; COMPLEX MIXTURE; DECISION TREE ANALYSIS; FUROSEMIDES; GASTROPODS; GEMFIBROZILS; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; HEAT SHOCK PROTEIN 70; HYDROCHLOROTHIAZIDE; IMMUNE RESPONSE; IMMUNE SYSTEMS; IMMUNOCOMPETENCE; ISOFORMS; LISINOPRIL; LYMNAEA STAGNALIS; MUNICIPAL EFFLUENTS; NOVOBIOCIN; OXYTETRACYCLINES (OTC); PHARMACEUTICAL MIXTURES; SHORT-TERM EXPOSURE; SULFAMETHOXAZOLE; SUPEROXIDE DISMUTASES; SYNTHETASES; TARGET SPECIES; THERAPEUTIC CLASS; THERAPEUTIC USE; TOLL-LIKE RECEPTOR 4; TRIMETHOPRIM; VENLAFAXINE;

AMIDES; ANTIGEN-ANTIBODY REACTIONS; DECISION TREES; DRUG PRODUCTS; EFFLUENTS; ENZYME ACTIVITY; GENE EXPRESSION; MIXTURES; NITRIC OXIDE; OXYGEN; PEPTIDES; SELENIUM;

ANTIBIOTICS;

ALLOGRAFT INFLAMMATORY FACTOR 1; ATENOLOL; ATORVASTATIN; BEZAFIBRATE; CARBAMAZEPINE; CIPROFLOXACIN; DIAZEPAM; DRUG; ERYTHROMYCIN; FUROSEMIDE; GEMFIBROZIL; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; HEAT SHOCK PROTEIN 70; HYDROCHLOROTHIAZIDE; INDUCIBLE NITRIC OXIDE SYNTHASE; LISINOPRIL; MESSENGER RNA; NEURONAL NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE; NOVOBIOCIN; OXYTETRACYCLINE; REACTIVE OXYGEN METABOLITE; SULFAMETHOXAZOLE; SUPEROXIDE DISMUTASE; TOLL LIKE RECEPTOR 4; TRIMETHOPRIM; VENLAFAXINE;

AQUATIC ENVIRONMENT; CONCENTRATION (COMPOSITION); DRUG; EFFLUENT; ENVIRONMENTAL FACTOR; ENVIRONMENTAL STRESS; GASTROPOD; GENE EXPRESSION; IMMUNE RESPONSE; MODELING; TOXICITY;

ARTICLE; BLOOD CELL; CELL VIABILITY; CONTROLLED STUDY; DECISION TREE; DOWN REGULATION; EFFLUENT; ENVIRONMENTAL EXPOSURE; FLOW CYTOMETRY; GASTROPOD; GENE EXPRESSION; HIGH THROUGHPUT SCREENING; IMMUNE RESPONSE; IMMUNOCOMPETENCE; LYMNAEA; LYMNAEA STAGNALIS; NONHUMAN; OXIDATIVE STRESS; PHAGOCYTOSIS; PRIORITY JOURNAL; RISK ASSESSMENT;

ANIMALS; DECISION TREES; ENVIRONMENTAL EXPOSURE; ENVIRONMENTAL MONITORING; IMMUNITY, INNATE; IMMUNOCOMPETENCE; LYMNAEA; OXIDATIVE STRESS; PONDS; RISK ASSESSMENT; TOXICITY TESTS; WATER POLLUTANTS, CHEMICAL;

GASTROPODA; LYMNAEA STAGNALIS; LYMNAEIDAE;

EID: 84872471449     PISSN: 00489697     EISSN: 18791026     Source Type: Journal    
DOI: 10.1016/j.scitotenv.2012.12.057     Document Type: Article

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