Lipopolysaccharide directly alters renal tubule transport through distinct TLR4-dependent pathways in basolateral and apical membranes

American Journal of Physiology - Renal Physiology

Volumn 297, Issue 4, 2009, Pages

  Good, David W ^a,b   George, Thampi ^a   Watts III, Bruns A ^a  

^a University of Texas Medical Branch School of Medicine   (United States)

^b UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

Author keywords

Acid base transport; Bacterial kidney infection; Medullary thick ascending limb; Na+ H+ exchange; Sepsis

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; AMILORIDE; BICARBONATE; LIPOPOLYSACCHARIDE; MAMMALIAN TARGET OF RAPAMYCIN INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE; RAPAMYCIN; TOLL LIKE RECEPTOR 4;

ANIMAL CELL; ANIMAL TISSUE; APICAL MEMBRANE; ARTICLE; BACTERIAL INFECTION; BACTERIAL VIRULENCE; BACTERIUM ADHERENCE; BASOLATERAL MEMBRANE; CONTROLLED STUDY; ENZYME INHIBITION; GRAM NEGATIVE BACTERIUM; KIDNEY FUNCTION; KIDNEY TUBULE ABSORPTION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTON SODIUM EXCHANGE; RAT;

EID: 70349639668     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00335.2009     Document Type: Article

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