TLR-4 mediated group IVA phospholipase A2 activation is phosphatidic acid phosphohydrolase 1 and protein kinase C dependent

Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids

Volumn 1791, Issue 10, 2009, Pages 975-982

  Grkovich, Andrej ^a   Armando, Aaron ^a   Quehenberger, Oswald ^b   Dennis, Edward A ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

Arachidonic acid (AA); Eicosanoid; Group IVA phospholipase 2 (GIVA PLA2); Inflammation; Lipopolysaccharide (LPS); Macrophage; Phosphatidic acid phosphohydrolase 1 (PAP 1); Protein Kinase C (PKC); Signal transduction

Indexed keywords

2 [1 (3 AMIDINOTHIOPROPYL) 1H INDOL 3 YL] 3 (1 METHYL 1H INDOL 3 YL)MALEIMIDE; 3 DEOXY MANNO OCTULOSONIC ACID; ADENOSINE TRIPHOSPHATE; ARACHIDONIC ACID; BROMOENOL LACTONE; CALCIUM ION; DIACYLGLYCEROL; LIPID A; PHOSPHATIDATE PHOSPHATASE; PHOSPHATIDIC ACID PHOSPHOHYDROLASE 1; PHOSPHOLIPASE A2 GROUP IV; PHOSPHOLIPASE A2 GROUP IVA; PROPRANOLOL; PROTEIN KINASE C; PURINERGIC P2X7 RECEPTOR; TOLL LIKE RECEPTOR 4; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CALCIUM TRANSPORT; CELL STIMULATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; HYDROLYSIS; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION;

ADENOSINE TRIPHOSPHATE; ANIMALS; ARACHIDONIC ACID; DIGLYCERIDES; DRUG SYNERGISM; EDETIC ACID; EGTAZIC ACID; ENZYME ACTIVATION; GROUP IV PHOSPHOLIPASES A2; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; NAPHTHALENES; PHOSPHATIDATE PHOSPHATASE; PROPRANOLOL; PROTEIN KINASE C; PYRONES; TIME FACTORS; TOLL-LIKE RECEPTOR 4;

EID: 69949087297     PISSN: 13881981     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbalip.2009.02.002     Document Type: Article

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