Soy-based diet exacerbates seizures in mouse models of neurological disease

Journal of Alzheimer's Disease

Volumn 33, Issue 3, 2013, Pages 797-805

  Westmark, Cara J ^a   Westmark, Pamela R ^a   Malter, James S ^b  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

amyloid protein precursor; Amyloid ; daidzein; isoflavone; seizure; soy

Indexed keywords

AMYLOID PRECURSOR PROTEIN; D07030301; DAIDZEIN; FENOBAM; GENISTEIN; PHYTOESTROGEN; PURINA 5015; SOYBEAN PROTEIN; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DENDRITIC CELL; DIET SUPPLEMENTATION; DISEASE EXACERBATION; DOWN SYNDROME; FEMALE; FRAGILE X SYNDROME; IN VITRO STUDY; IN VIVO STUDY; MALE; MORTALITY; MOUSE; NERVE CELL CULTURE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RUNNING; SEIZURE; SOYBEAN;

EID: 84872468914     PISSN: 13872877     EISSN: 18758908     Source Type: Journal    
DOI: 10.3233/JAD-2012-121426     Document Type: Article

References (42)

1. Berry-Kravis E, Raspa M, Loggin-Hester L, Bishop E, Holiday D, Bailey DB (2010) Seizures in fragile X syndrome: Characteristics and comorbid diagnoses. Am J Intellect Dev Disabil 115, 461-472.
2. Musumeci SA, Bosco P, Calabrese G, Bakker C, De Sarro GB, Elia M, Ferri R, Oostra BA (2000) Audiogenic seizures susceptibility in transgenic mice with fragile X syndrome. Epilepsia 41, 19-23. (Pubitemid 30036849)
3. Chen L, TothM(2001) FragileXmice develop sensory hyperreactivity to auditory stimuli. Neuroscience 103, 1043-1050. (Pubitemid 32289314)
4. Yan QJ, Rammal M, Tranfaglia M, Bauchwitz RP (2005) Suppression of two major Fragile X Syndrome mouse model phenotypes by the mGluR5 antagonist MPEP. Neuropharmacology 49, 1053-1066. (Pubitemid 41503304)
5. Berry-Kravis E (2002) Epilepsy in fragile X syndrome. Dev Med Child Neurol 44, 724-728. (Pubitemid 35230036)
6. Westmark CJ, Malter JS (2007) FMRP mediates mGluR5-dependent translation of amyloid precursor protein. PLoS Biol 5, e52.
7. Westmark CJ, Westmark PR, Malter JS (2010) Alzheimer's disease and Down syndrome rodent models exhibit audiogenic seizures. J Alzheimers Dis 20, 1009-1013.
8. Westmark CJ, Westmark P, Beard A, Hildebrandt S, Malter JS (2008) Seizure susceptibility and mortality in mice that over-Express amyloid precursor protein. Int J Clin Exp Pathol 1, 157-168.
9. Westmark CJ, Westmark PR, O'Riordan KJ, Ray BC, Hervey CM, Salamat MS, Abozeid SH, Stein KM, Stodola LA, Tranfaglia M, Burger C, Berry-Kravis EM, Malter JS (2011) Reversal of Fragile X phenotypes by manipulation of A-PP/A levels in Fmr1 mice. PLoS One 6, e26549.
10. Ricci MR, Ulman EA (2005) Laboratory animal diets: A critical part of your research. Animal Lab News 4, 1.
11. Brown NM, Setchell KD (2001) Animal models impacted by phytoestrogens in commercial chow: Implications for pathways influenced by hormones. Lab Invest 81, 735-747. (Pubitemid 32466536)
12. The Dutch-Belgian Fragile X Consortium (1994) Fmr1 knockout mice:Amodel to study fragileXmental retardation. Cell 78, 23-33.
13. Hsiao K, Chapman P, Nilsen S, Eckman C, Harigaya Y, Younkin S, Yang F, Cole G (1996) Correlative memory deficits, Abeta elevation, and amyloid plaques in transgenic mice. Science 274, 99-102. (Pubitemid 26332733)
14. Davisson MT, Schmidt C, Akeson EC (1990) Segmental trisomy of murine chromosome 16: A new model system for studying Down syndrome. Prog Clin Biol Res 360, 263-280.
15. Schlesinger K, Griek BJ (1970) The genetics and biochemistry of audiogenic seizures. In Contributions to Behavior-Genetic Analysis. The Mouse as a Prototype, Lindzey G, Thiessen DD, eds. Appleton-Century-Crofts, New York, pp. 219-257.
16. Thigpen JE, Li LA, Richter CB, Lebetkin EH, Jameson CW (1987) The mouse bioassay for the detection of estrogenic activity in rodent diets: II. Comparative estrogenic activity of purified, certified and standard open and closed formula rodent diets. Lab Anim Sci 37, 602-605.
17. Santell RC, Kieu N, Helferich WG (2000) Genistein inhibits growth of estrogen-independent human breast cancer cells in culture but not in athymic mice. J Nutr 130, 1665-1669. (Pubitemid 30451050)
18. Wisniewski KE, Segan SM, Miezejeski CM, Sersen EA, Rudelli RD (1991) The Fra(X) syndrome: Neurological, electrophysiological, and neuropathological abnormalities. Am J Med Genet 38, 476-480.
19. Volkmar FR, Nelson DS (1990) Seizure disorders in autism. J Am Acad Child Adolesc Psychiatry 29, 127-129. (Pubitemid 20077239)
20. Hauser WA, Morris ML, Heston LL, Anderson VE (1986) Seizures and myoclonus in patients with Alzheimer's disease. Neurology 36, 1226-1230. (Pubitemid 16047002)
21. Pueschel SM, Louis S, McKnight P (1991) Seizure disorders in Down syndrome. Arch Neurol 48, 318-320.
22. Chen JW, Ruff RL, Eavey R,Wasterlain CG (2009) Posttraumatic epilepsy and treatment. J Rehabil Res Dev 46, 685-696.
23. Weiss GH, Salazar AM, Vance SC, Grafman JH, Jabbari B (1986) Predicting posttraumatic epilepsy in penetrating head injury. Arch Neurol 43, 771-773. (Pubitemid 16034223)
24. Ikonomidou C, Turski L (2010) Antiepileptic drugs and brain development. Epilepsy Res 88, 11-22.
25. Noebels J (2011) A perfect storm: Converging paths of epilepsy and Alzheimer's dementia intersect in the hippocampal formation. Epilepsia 52(Suppl 1), 39-46.
26. Chang S, Bray SM, Li Z, Zarnescu DC, He C, Jin P, Warren ST (2008) Identification of small molecules rescuing fragile Xsyndrome phenotypes in Drosophila. Nat Chem Biol 4, 256-263. (Pubitemid 351419125)
27. Skeie B, Petersen AJ, Manner T, Askanazi J, Jellum E, Steen PA (1992) Branched-chain amino acids increase the seizure threshold to picrotoxin in rats. Pharmacol Biochem Behav 43, 669-671.
28. Harris RA, Joshi M, Jeoung NH, Obayashi M (2005) Overview of the molecular and biochemical basis of branched-chain amino acid catabolism. J Nutr 135, 1527S-1530S.
29. Atkinson C, Frankenfeld CL, Lampe JW (2005) Gut bacterial metabolism of the soy isoflavone daidzein: Exploring the relevance to human health. Exp Biol Med (Maywood) 230, 155-170. (Pubitemid 40293689)
30. Lephart ED, Adlercreutz H, Lund TD (2001) Dietary soy phytoestrogen effects on brain structure and aromatase in Long-Evans rats. Neuroreport 12, 3451-3455. (Pubitemid 33065476)
31. Misawa H, Sherr EH, Lee DJ, Chetkovich DM, Tan A, Schreiner CE, Bredt DS (2002) Identification of a monogenic locus (jams1) causing juvenile audiogenic seizures in mice. J Neurosci 22, 10088-10093. (Pubitemid 35416847)
32. Neumann PE, Collins RL (1991) Genetic dissection of susceptibility to audiogenic seizures in inbred mice. Proc Natl Acad Sci U S A 88, 5408-5412. (Pubitemid 21914754)
33. Mendez M, Lim G (2003) Seizures in elderly patients with dementia: Epidemiology and management. Drugs Aging 20, 791-803. (Pubitemid 37159597)
34. Musumeci SA, Hagerman RJ, Ferri R, Bosco P, Dalla Bernardina B, Tassinari CA, De Sarro GB, Elia M (1999) Epilepsy andEEGfindings in males with fragileXsyndrome. Epilepsia 40, 1092-1099.
35. Giovanardi Rossi P, Posar A, Parmeggiani A (2000) Epilepsy in adolescents and young adults with autistic disorder. Brain Dev 22, 102-106. (Pubitemid 30155636)
36. Soucy NV, Parkinson HD, Sochaski MA, Borghoff SJ (2006) Kinetics of genistein and its conjugated metabolites in pregnant Sprague-Dawley rats following single and repeated genistein administration. Toxicol Sci 90, 230-240. (Pubitemid 43264743)
37. American Academy of Pediatrics. Committee on Nutrition (1998) American Academy of Pediatrics. Committee on Nutrition. Soy protein-based formulas: Recommendations for use in infant feeding. Pediatrics 101, 148-153.
38. Setchell KD, Zimmer-Nechemias L, Cai J, Heubi JE (1997) Exposure of infants to phyto-oestrogens from soy-based infant formula. Lancet 350, 23-27.
39. Setchell KD, Zimmer-Nechemias L, Cai J, Heubi JE (1998) Isoflavone content of infant formulas and the metabolic fate of these phytoestrogens in early life. Am J Clin Nutr 68, 1453S-1461S.
40. Chen A, Rogan WJ (2004) Isoflavones in soy infant formula: A review of evidence for endocrine and other activity in infants. Annu Rev Nutr 24, 33-54. (Pubitemid 38938785)
41. Cirrito JR, Yamada KA, Finn MB, Sloviter RS, Bales KR, May PC, Schoepp DD, Paul SM, Mennerick S, HoltzmanDM (2005) Synaptic activity regulates interstitial fluid amyloidbeta levels in vivo. Neuron 48, 913-922. (Pubitemid 41814696)
42. Westmark CJ (2012) What's hAPPening at synapses? The role of amyloid -protein precursor and -amyloid in neurological disorders. Molecular Psychiatry, doi: 10.1038/mp.2012.122.