Use of biomarkers and imaging to assess pathophysiology, mechanisms of action and target engagement

Journal of Nutrition, Health and Aging

Volumn 17, Issue 1, 2013, Pages 54-63

  Hampel, Harald ^a   Lista, S ^a  

^a GOETHE UNIVERSITY   (Germany)

Author keywords

AD; Alzheimer's disease; amyloid cascade hypothesis; amyloid beta; asymptomatic; biomarkers; blood; clinical trials; CSF; disease modifying compounds; early detection; MCI; mechanism of action; neurobiochemical markers; pathophysiological mechanisms; prevention trials; prodromal; target engagement; tau; theragnostic biomarkers; therapy

Indexed keywords

ALZHEIMER DISEASE VACCINE; AMYLOID BETA PROTEIN[1-42]; BIOLOGICAL MARKER; LITHIUM; TAU PROTEIN;

ALZHEIMER DISEASE; ARTICLE; DRUG EFFECT; DRUG TARGETING; HUMAN; IMAGING; MOLECULAR MECHANICS; NONHUMAN; PATHOPHYSIOLOGY; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN CEREBROSPINAL FLUID LEVEL; PROTEIN METABOLISM;

EID: 84872464390     PISSN: 12797707     EISSN: 17604788     Source Type: Journal    
DOI: 10.1007/s12603-013-0003-1     Document Type: Article

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