Nuclear factor κB down-regulates human UDP-glucuronosyltransferase 1A1: A novel mechanism involved in inflammation-associated hyperbilirubinaemia

Biochemical Journal

Volumn 449, Issue 3, 2013, Pages 761-770

  Shiu, Tzu Yue ^a,b   Huang, Tien Yu ^b   Huang, Shih Ming ^a   Shih, Yu Lueng ^b   Chu, Heng Cheng ^b   Chang, Wei Kuo ^b   Hsieh, Tsai Yuan ^b  

^a NATIONAL DEFENSE MEDICAL CENTER   (Taiwan)

^b TRI SERVICE GENERAL HOSPITAL   (Taiwan)

Author keywords

Hyperbilirubinaemia; Inhibitor; Lipopolysaccharide (LPS); Nuclear factor B (NF B); Promoter; UDP glucuronosyltransferase 1A1 (UGT1A1)

Indexed keywords

GLUCURONOSYLTRANSFERASE 1A1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOPOLYSACCHARIDE;

ANIMAL EXPERIMENT; ARTICLE; BINDING SITE; CANCER CELL CULTURE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DISEASE ASSOCIATION; DOWN REGULATION; ENZYME ACTIVATION; GEL MOBILITY SHIFT ASSAY; HUMAN; HUMAN CELL; HYPERBILIRUBINEMIA; INFLAMMATION; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ANIMALS; BASE SEQUENCE; BINDING SITES; CELL LINE; DNA, COMPLEMENTARY; DOWN-REGULATION; GLUCURONOSYLTRANSFERASE; HEP G2 CELLS; HUMANS; HYPERBILIRUBINEMIA; INFLAMMATION; LIPOPOLYSACCHARIDES; LIVER; MICE; MICE, INBRED C57BL; MODELS, BIOLOGICAL; NF-KAPPA B; PROMOTER REGIONS, GENETIC; RNA, MESSENGER;

EID: 84872441907     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20121055     Document Type: Article

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