Molecular pathogenesis of Gilbert's syndrome: Decreased TATA-binding protein binding affinity of UGT1A1 gene promoter

Pharmacogenetics and Genomics

Volumn 17, Issue 4, 2007, Pages 229-236

  Hsieh, Tsai Yuan ^a   Shiu, Tzu Yue ^a   Huang, Shih Ming ^b   Lin, Hsuan Hwai ^a   Lee, Tai Chi ^a   Chen, Peng Jen ^a   Chu, Heng Cheng ^a   Chang, Wei Kuo ^a   Jeng, King Song ^c   Lai, Michael M C ^c   Chao, You Chen ^a,b  

^a TRI SERVICE GENERAL HOSPITAL   (Taiwan)

^b NATIONAL DEFENSE MEDICAL CENTER   (Taiwan)

^c INSTITUTE OF MOLECULAR BIOLOGY   (Taiwan)

Author keywords

Electrophoretic mobility shift assay; Gilbert's syndrome; TATA binding protein; UDP glucuronosyltransferase 1A1

Indexed keywords

GLUCURONOSYLTRANSFERASE 1A1; OLIGONUCLEOTIDE; TATA BINDING PROTEIN;

AMINO ACID SEQUENCE; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; ENZYME ACTIVITY; GEL MOBILITY SHIFT ASSAY; GENE ACTIVITY; GENE INSERTION; GILBERT DISEASE; HEPATOMA CELL; HUMAN; HUMAN CELL; OLIGONUCLEOTIDE PROBE; PATHOGENESIS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING;

BASE SEQUENCE; CELL LINE; DNA PRIMERS; ELECTROPHORETIC MOBILITY SHIFT ASSAY; GILBERT DISEASE; GLUCURONOSYLTRANSFERASE; HUMANS; KINETICS; MUTAGENESIS, INSERTIONAL; PHARMACOGENETICS; PROMOTER REGIONS (GENETICS); TATA-BOX BINDING PROTEIN;

EID: 34247597891     PISSN: 17446872     EISSN: 17446880     Source Type: Journal    
DOI: 10.1097/FPC.0b013e328012d0da     Document Type: Article

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