Gata3 directly regulates early inner ear expression of Fgf10

Developmental Biology

Volumn 374, Issue 1, 2013, Pages 210-222

  Economou, Androulla ^a   Datta, Preeta ^a   Georgiadis, Vassilis ^a   Cadot, Stephanie ^a   Frenz, Dorothy ^b   Maconochie, Mark ^a  

^a UNIVERSITY OF SUSSEX   (United Kingdom)

^b NEW YORK MEDICAL COLLEGE   (United States)

Author keywords

EMSA; Enhancer; Fgf10; Gata3; Inner ear; Otic vesicle; Otocyst; Retinoic acid; Transgenic mice

Indexed keywords

DNA; FIBROBLAST GROWTH FACTOR 10; TRANSCRIPTION FACTOR GATA 3;

ANIMAL TISSUE; ARTICLE; BINDING SITE; CONTROLLED STUDY; DNA FLANKING REGION; DNA SEQUENCE; EMBRYO; FEMALE; GANGLION; GEL MOBILITY SHIFT ASSAY; GENE EXPRESSION; GESTATION PERIOD; INNER EAR; MALE; MOLECULAR CLONING; MOUSE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN INTERACTION; REGULATORY MECHANISM; SITE DIRECTED MUTAGENESIS; TRANSGENE; TRANSGENIC MOUSE;

MUS; MUS MUSCULUS; VERTEBRATA;

EID: 84872422510     PISSN: 00121606     EISSN: 1095564X     Source Type: Journal    
DOI: 10.1016/j.ydbio.2012.11.028     Document Type: Article

References (58)

1. Adamska M., Herbrand H., Adamski M., Kruger M., Braun T., Bober E. FGFs control the patterning of the inner ear but are not able to induce the full ear program. Mech. Dev. 2001, 109:303-313.
2. Alvarez Y., Alonso M., Vendrell V., Zelarayan L., Chamero P., Theil T., Bosl M., Kato S., Maconochie M., Riethmacher D., Schimmang T. Requirements for FGF-3 and FGF-10 during inner ear formation. Development 2003, 130:6329-6338.
3. Bok J., Raft S., Kong K.A., Koo S.K., Drager U.C., Wu D.K. Transient retinoic acid signaling confers anterior-posterior polarity to the inner ear. Proc. Natl. Acad. Sci. USA 2011, 108:161-166.
4. Cadot S., Frenz D., Maconochie M. A novel method for retinoic acid administration reveals differential and dose-dependent downregulation of Fgf3 in the developing inner ear and anterior CNS. Dev. Dyn. 2012, 241:741-758.
5. Carnicero E., Garrido J.J., Alonso M.T., Schimmang T. Roles of fibroblast growth factor 2 during innervation of the avian inner ear. J. Neurochem. 2001, 77:786-795.
6. Chang W., Brigande J.V., Fekete D.M., Wu D.K. The development of semicircular canals in the inner ear: role of FGFs in sensory cristae. Development 2004, 131:4201-4211.
7. Deng M., Pan L., Xie X., Gan L. Requirement for Lmo4 in the vestibular morphogenesis of mouse inner ear. Dev. Biol. 2010, 338:38-49.
8. Dominguez-Frutos E., Vendrell V., Alvarez Y., Zelarayan L.C., Lopez-Hernandez I., Ros M., Schimmang T. Tissue-specific requirements for FGF8 during early inner ear development. Mech. Dev. 2009, 126:873-881.
9. Duncan J.S., Lim K.C., Engel J.D., Fritzsch B. Limited inner ear morphogenesis and neurosensory development are possible in the absence of GATA3. Int. J. Dev. Biol. 2011, 55:297-303.
10. El Agha E., Al Alam D., Carraro G., MacKenzie B., Goth K., De Langhe S.P., Voswinckel R., Hajihosseini M.K., Rehan V.K., Bellusci S. Characterization of a novel fibroblast growth factor 10 (Fgf10) knock-in mouse line to target mesenchymal progenitors during embryonic development. PLoS ONE 2012, 7:e38452.
11. Fantetti K.N., Fekete D.M. Members of the BMP, Shh and FGF morphogen families promote chicken statoacoustic ganglion neurite outgrowth and neuron survival in vitro. Dev. Neurobiol. 2012, 72:1213-1228.
12. Fekete D.M. Cell fate specification in the inner ear. Curr. Opinion Neurobiol. 1996, 6:533-541.
13. Fekete D.M., Wu D.K. Revisiting cell fate specification in the inner ear. Curr. Opinion Neurobiol. 2002, 12:35-42.
14. Frenz D.A., Liu W., Cvekl A., Xie Q., Wassef L., Quadro L., Niederreither K., Maconochie M., Shanske A. Retinoid signaling in inner ear development: a "Goldilocks" phenomenon. Am. J. Med. Genet. A 2010, 152A:2947-2961.
15. Glover J.C., Renaud J.S., Rijli F.M. Retinoic acid and hindbrain patterning. J. Neurobiol. 2006, 66:705-725.
16. Golzio C., Havis E., Daubas P., Nuel G., Babarit C., Munnich A., Vekemans M., Zaffran S., Lyonnet S., Etchevers H.C. ISL1 directly regulates FGF10 transcription during human cardiac outflow formation. PLoS ONE 2012, 7:e30677.
17. Gotea V., Visel A., Westlund J.M., Nobrega M.A., Pennacchio L.A., Ovcharenko I. Homotypic clusters of transcription factor binding sites are a key component of human promoters and enhancers. Genome Res. 2010, 20:565-577.
18. Hammond K.L., Whitfield T.T. Fgf and Hh signalling act on a symmetrical pre-pattern to specify anterior and posterior identity in the zebrafish otic placode and vesicle. Development 2011, 138:3977-3987.
19. Hans S., Christison J., Liu D., Westerfield M. Fgf-dependent otic induction requires competence provided by Foxi1 and Dlx3b. BMC Dev. Biol. 2007, 7:5.
20. Hans S., Liu D., Westerfield M. Pax8 and Pax2a function synergistically in otic specification, downstream of the Foxi1 and Dlx3b transcription factors. Development 2004, 131:5091-5102.
21. Hans S., Westerfield M. Changes in retinoic acid signaling alter otic patterning. Development 2007, 134:2449-2458.
22. Hatch E.P., Noyes C.A., Wang X., Wright T.J., Mansour S.L. Fgf3 is required for dorsal patterning and morphogenesis of the inner ear epithelium. Development 2007, 134:3615-3625.
23. Haugas M., Lillevali K., Hakanen J., Salminen M. Gata2 is required for the development of inner ear semicircular ducts and the surrounding perilymphatic space. Dev. Dyn. 2010, 239:2452-2469.
24. Haugas M., Lillevali K., Salminen M. Defects in sensory organ morphogenesis and generation of cochlear hair cells in Gata3-deficient mouse embryos. Hear. Res. 2012, 283:151-161.
25. Hayashi T., Ray C.A., Bermingham-McDonogh O. Fgf20 is required for sensory epithelial specification in the developing cochlea. J. Neurosci. 2008, 28:5991-5999.
26. Hogan B., Beddington R., Constantini F., Lacy E. Manipulating the Mouse Embryo 1994, Cold Spring Harbor Laboratory Press, New York.
27. Hossain W.A., Zhou X., Rutledge A., Baier C., Morest D.K. Basic fibroblast growth factor affects neuronal migration and differentiation in normotypic cell cultures from the cochleovestibular ganglion of the chick embryo. Exp. Neurol. 1996, 138:121-143.
28. Huh S.H., Jones J., Warchol M.E., Ornitz D.M. Differentiation of the lateral compartment of the cochlea requires a temporally restricted FGF20 signal. PLoS Biol. 2012, 10:e1001231.
29. Hutson M.R., Lewis J.E., Nguyen-Luu D., Lindberg K.H., Barald K.F. Expression of Pax2 and patterning of the chick inner ear. J. Neurocytol. 1999, 28:795-807.
30. Jacques B.E., Montcouquiol M.E., Layman E.M., Lewandoski M., Kelley M.W. Fgf8 induces pillar cell fate and regulates cellular patterning in the mammalian cochlea. Development 2007, 134:3021-3029.
31. Karis A., Pata I., van Doornick J., Grosveld F., de Zeeuw C., de Caprona D., Fritzsch B. Transcription factor Gata3 alters pathway selection of olivocochlear neurons and affects morphogenesis of the ear. J. Comp. Neurol. 2001, 429:615-630.
32. Kelly R.G., Brown N.A., Buckingham M.E. The arterial pole of the mouse heart forms from Fgf10-expressing cells in pharyngeal mesoderm. Dev. Cell 2001, 1:435-440.
33. Kiernan A.E., Steel K.P., Fekete D.M. Development of the mouse inner ear. Mouse Development, Patterning, Morphogenesis and Organogenesis 2002, Academic Press, London, pp. 539-566. J. Rossant, P. Tam (Eds.).
34. Ladher R.K., Wright T.J., Moon A., Mansour S.L., Schoenwolf G.C. FGF8 initiates inner ear induction in chick and mouse. Genes Dev. 2005, 19:603-613.
35. Lawoko-Kerali G., Rivolta M., Holley M. Expression of the transcription factors GATA3 and Pax2 during development of the mammalian inner ear. J. Comp. Neurol. 2002, 442:378-391.
36. Lifanov A.P., Makeev V.J., Nazina A.G., Papatsenko D.A. Homotypic regulatory clusters in Drosophila. Genome Res. 2003, 13:579-588.
37. Lillevali K., Haugas M., Matilainen T., Pussinen C., Karis A., Salminen M. Gata3 is required for early morphogenesis and Fgf10 expression during otic development. Mech. Dev. 2006, 123:415-429.
38. Lillevali K., Matilainen T., Karis A., Salminen M. Partially overlapping expression of Gata2 and Gata3 during inner ear development. Dev. Dyn. 2004, 231:775-781.
39. Liu D., Chu H., Maves L., Yan Y.L., Morcos P.A., Postlethwait J.H., Westerfield M. Fgf3 and Fgf8 dependent and independent transcription factors are required for otic placode specification. Development 2003, 130:2213-2224.
40. Mansour S.L., Goddard J.M., Capecchi M.R. Mice homozygous for a targeted disruption of the proto-oncogene int-2 have developmental defects in the tail and inner ear. Development 1993, 117:13-28.
41. Nardelli J., Thiesson D., Fujiwara Y., Tsai F.Y., Orkin S.H. Expression and genetic interaction of transcription factors GATA-2 and GATA-3 during development of the mouse central nervous system. Dev. Biol. 1999, 210:305-321.
42. Nonchev S., Maconochie M. Spatial analysis of gene expression. Mouse Genetics and Transgenics: A Practical Approach 1999, Oxford University Press, pp. 61-86. I.J. Jackson, C.M. Abbott (Eds.).
43. Ohuchi H., Yasue A., Ono K., Sasaoka S., Tomonari S., Takagi A., Itakura M., Moriyama K., Noji S., Nohno T. Identification of cis-element regulating expression of the mouse Fgf10 gene during inner ear development. Dev. Dyn. 2005, 233:177-187.
44. Ohyama T., Groves A.K., Martin K. The first steps towards hearing: mechanisms of otic placode induction. Int. J. Dev. Biol. 2007, 51:463-472.
45. Pata I., Studer M., van Doorninck J.H., Briscoe J., Kuuse S., Engel J.D., Grosveld F., Karis A. The transcription factor GATA3 is a downstream effector of Hoxb1 specification in rhombomere 4. Development 1999, 126:5523-5531.
46. Pauley S., Wright T., Pirvola U., Ornitz D., Biesel K., Fritzsch B. Expression and function of FGF10 in mammalian inner ear development. Dev. Dyn. 2003, 227:203-215.
47. Quandt K., Frech K., Karas H., Wingender E., Werner T. MatInd and MatInspector: New fast and versatile tools for detection of consensus matches in nucleotide sequence data. Nucleic Acids Res. 1995, 23:4878-4884.
48. Romand R., Dolle P., Hashino E. Retinoid signaling in inner ear development. J. Neurobiol. 2006, 66:687-704.
49. Romand R., Kondo T., Fraulob V., Petkovich M., Dolle P., Hashino E. Dynamic expression of retinoic acid-synthesizing and -metabolizing enzymes in the developing mouse inner ear. J. Comp. Neurol. 2006, 496:643-654.
50. Sasak H., Yamaoka T., Ohuchi H., Yasue A., Nohno T., Kawano H., Kato S., Itakura M., Nagayama M., Noji S. Identification of cis-elements regulating expression of Fgf10 during limb development. Int. J. Dev. Biol. 2002, 46:963-967.
51. Schimmang T. Expression and functions of FGF ligands during early otic development. Int. J. Dev. Biol. 2007, 51:473-481.
52. Sweet E.M., Vemaraju S., Riley B.B. Sox2 and Fgf interact with Atoh1 to promote sensory competence throughout the zebrafish inner ear. Dev. Biol. 2011, 358:113-121.
53. Torres M., Giraldez F. The development of the vertebrate inner ear. Mech. Dev. 1998, 71:5-21.
54. Tsai F.Y., Keller G., Kuo F.C., Weiss M., Chen J., Rosenblatt M., Alt F.W., Orkin S.H. An early haematopoietic defect in mice lacking the transcription factor GATA-2. Nature 1994, 371:221-226.
55. Urness L.D., Bleyl S.B., Wright T.J., Moon A.M., Mansour S.L. Redundant and dosage sensitive requirements for Fgf3 and Fgf10 in cardiovascular development. Dev. Biol. 2011, 356:383-397.
56. Wood H., Pall G., Morriss-Kay G. Exposure to retinoic acid before or after the onset of somitogenesis reveals separate effects on rhombomeric segmentation and 3' HoxB gene expression domains. Development 1994, 120:2279-2285.
57. Wright T.J., Mansour S.L. Fgf3 and Fgf10 are required for mouse otic placode induction. Development 2003, 130:3379-3390.
58. Zelarayan L.C., Vendrell V., Alvarez Y., Dominguez-Frutos E., Theil T., Alonso M.T., Maconochie M., Schimmang T. Differential requirements for FGF3, FGF8 and FGF10 during inner ear development. Dev. Biol. 2007, 308:379-391.